| 1 | #include <stdio.h> |
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| 2 | #include <stdlib.h> |
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| 3 | #include <string.h> |
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| 4 | |
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| 5 | #include <adlocal.h> |
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| 6 | #include <arbdbt.h> |
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| 7 | |
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| 8 | /* -------------------------------------------------------------------------------- */ |
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| 9 | |
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| 10 | #define MAX_SEQUENCE_PER_MASTER 50 /* was 18 till May 2008 */ |
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| 11 | |
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| 12 | #if defined(DEBUG) |
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| 13 | /* don't do optimize, only create tree and save to DB */ |
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| 14 | /* #define SAVE_COMPRESSION_TREE_TO_DB */ |
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| 15 | #endif /* DEBUG */ |
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| 16 | |
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| 17 | /* -------------------------------------------------------------------------------- */ |
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| 18 | |
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| 19 | typedef struct gb_seq_compr_tree { |
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| 20 | #ifdef FAKE_VTAB_PTR |
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| 21 | virtualTable *dummy_virtual; /* simulate pointer to virtual-table used in AP_tree */ |
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| 22 | #endif |
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| 23 | GBT_TREE_ELEMENTS(struct gb_seq_compr_tree); |
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| 24 | |
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| 25 | int index; /* master(inner nodes) or sequence(leaf nodes) index */ |
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| 26 | int sons; /* sons with sequence or masters (in subtree) */ |
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| 27 | } GB_CTREE; |
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| 28 | |
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| 29 | typedef struct { |
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| 30 | int len; |
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| 31 | char used[256]; |
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| 32 | unsigned char *con[256]; |
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| 33 | } GB_Consensus; |
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| 34 | |
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| 35 | typedef struct { |
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| 36 | GBDATA *gbd; |
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| 37 | int master; |
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| 38 | } GB_Sequence; |
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| 39 | |
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| 40 | typedef struct { |
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| 41 | GBDATA *gbd; |
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| 42 | int master; |
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| 43 | } GB_Master; |
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| 44 | |
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| 45 | /* -------------------------------------------------------------------------------- */ |
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| 46 | |
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| 47 | GB_Consensus *g_b_new_Consensus(long len){ |
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| 48 | GB_Consensus *gcon = (GB_Consensus *)GB_calloc(sizeof(GB_Consensus),1); |
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| 49 | int i; |
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| 50 | unsigned char *data = (unsigned char *)GB_calloc(sizeof(char)*256,len); |
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| 51 | gcon->len = len; |
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| 52 | |
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| 53 | for (i=0;i<256;i++){ |
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| 54 | gcon->con[i] = data + len*i; |
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| 55 | } |
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| 56 | return gcon; |
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| 57 | } |
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| 58 | |
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| 59 | |
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| 60 | void g_b_delete_Consensus(GB_Consensus *gcon){ |
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| 61 | free((char *)gcon->con[0]); |
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| 62 | free((char *)gcon); |
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| 63 | } |
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| 64 | |
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| 65 | |
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| 66 | void g_b_Consensus_add(GB_Consensus *gcon, unsigned char *seq, long seq_len){ |
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| 67 | int i; |
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| 68 | int li; |
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| 69 | int c; |
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| 70 | unsigned char *s; |
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| 71 | int last; |
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| 72 | unsigned char *p; |
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| 73 | int eq_count; |
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| 74 | const int max_priority = 255/MAX_SEQUENCE_PER_MASTER; /* No overflow possible */ |
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| 75 | |
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| 76 | ad_assert(max_priority >= 1); |
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| 77 | |
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| 78 | if (seq_len > gcon->len) seq_len = gcon->len; |
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| 79 | |
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| 80 | /* Search for runs */ |
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| 81 | s = seq; |
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| 82 | last = 0; |
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| 83 | eq_count = 0; |
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| 84 | for (li = i = 0; i < seq_len; i++ ){ |
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| 85 | c = *(s++); |
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| 86 | if (c == last){ |
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| 87 | continue; |
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| 88 | }else{ |
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| 89 | inc_hits: |
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| 90 | eq_count = i-li; |
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| 91 | gcon->used[c] = 1; |
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| 92 | p = gcon->con[last]; |
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| 93 | last = c; |
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| 94 | if (eq_count <= GB_RUNLENGTH_SIZE) { |
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| 95 | c = max_priority; |
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| 96 | while (li < i) p[li++] += c; |
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| 97 | }else{ |
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| 98 | c = max_priority * ( GB_RUNLENGTH_SIZE ) / eq_count; |
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| 99 | if (c){ |
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| 100 | while (li < i) p[li++] += c; |
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| 101 | }else{ |
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| 102 | while (li < i) p[li++] |= 1; |
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| 103 | } |
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| 104 | } |
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| 105 | } |
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| 106 | } |
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| 107 | if (li<seq_len){ |
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| 108 | c = last; |
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| 109 | i = seq_len; |
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| 110 | goto inc_hits; |
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| 111 | } |
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| 112 | } |
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| 113 | |
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| 114 | char *g_b_Consensus_get_sequence(GB_Consensus *gcon){ |
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| 115 | int pos; |
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| 116 | unsigned char *s; |
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| 117 | unsigned char *max = (unsigned char *)GB_calloc(sizeof(char), gcon->len); |
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| 118 | int c; |
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| 119 | char *seq = (char *)GB_calloc(sizeof(char),gcon->len+1); |
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| 120 | |
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| 121 | memset(seq,'@',gcon->len); |
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| 122 | |
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| 123 | for (c = 1; c<256;c++){ /* Find maximum frequency of non run */ |
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| 124 | if (!gcon->used[c]) continue; |
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| 125 | s = gcon->con[c]; |
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| 126 | for (pos= 0;pos<gcon->len;pos++){ |
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| 127 | if (*s > max[pos]) { |
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| 128 | max[pos] = *s; |
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| 129 | seq[pos] = c; |
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| 130 | } |
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| 131 | s++; |
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| 132 | } |
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| 133 | } |
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| 134 | free((char *)max); |
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| 135 | return seq; |
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| 136 | } |
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| 137 | |
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| 138 | |
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| 139 | int g_b_count_leafs(GB_CTREE *node){ |
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| 140 | if (node->is_leaf) return 1; |
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| 141 | node->gb_node = 0; |
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| 142 | return (g_b_count_leafs(node->leftson) + g_b_count_leafs(node->rightson)); |
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| 143 | } |
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| 144 | |
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| 145 | void g_b_put_sequences_in_container(GB_CTREE *ctree,GB_Sequence *seqs,GB_Master **masters,GB_Consensus *gcon){ |
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| 146 | if (ctree->is_leaf){ |
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| 147 | if (ctree->index >= 0) { |
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| 148 | GB_CSTR data = GB_read_char_pntr(seqs[ctree->index].gbd); |
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| 149 | long len = GB_read_string_count(seqs[ctree->index].gbd); |
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| 150 | g_b_Consensus_add(gcon,(unsigned char *)data,len); |
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| 151 | } |
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| 152 | } |
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| 153 | else if (ctree->index<0){ |
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| 154 | g_b_put_sequences_in_container(ctree->leftson,seqs,masters,gcon); |
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| 155 | g_b_put_sequences_in_container(ctree->rightson,seqs,masters,gcon); |
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| 156 | } |
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| 157 | else { |
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| 158 | GB_CSTR data = GB_read_char_pntr(masters[ctree->index]->gbd); |
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| 159 | long len = GB_read_string_count(masters[ctree->index]->gbd); |
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| 160 | g_b_Consensus_add(gcon,(unsigned char *)data,len); |
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| 161 | } |
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| 162 | } |
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| 163 | |
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| 164 | void g_b_create_master(GB_CTREE *node, GB_Sequence *seqs, GB_Master **masters, |
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| 165 | int masterCount, int *builtMasters, int my_master, |
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| 166 | const char *ali_name, long seq_len, int *aborted) |
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| 167 | { |
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| 168 | if (*aborted) { |
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| 169 | return; |
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| 170 | } |
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| 171 | |
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| 172 | if (node->is_leaf){ |
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| 173 | if (node->index >= 0) { |
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| 174 | GBDATA *gb_data = GBT_read_sequence(node->gb_node, ali_name); |
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| 175 | |
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| 176 | seqs[node->index].gbd = gb_data; |
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| 177 | seqs[node->index].master = my_master; |
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| 178 | } |
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| 179 | } |
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| 180 | else { |
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| 181 | if (node->index>=0){ |
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| 182 | masters[node->index]->master = my_master; |
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| 183 | my_master = node->index; |
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| 184 | } |
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| 185 | g_b_create_master(node->leftson,seqs,masters,masterCount,builtMasters,my_master,ali_name,seq_len, aborted); |
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| 186 | g_b_create_master(node->rightson,seqs,masters,masterCount,builtMasters,my_master,ali_name,seq_len, aborted); |
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| 187 | if (node->index>=0 && !*aborted) { /* build me */ |
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| 188 | char *data; |
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| 189 | GB_Consensus *gcon = g_b_new_Consensus(seq_len); |
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| 190 | |
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| 191 | g_b_put_sequences_in_container(node->leftson,seqs,masters,gcon); |
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| 192 | g_b_put_sequences_in_container(node->rightson,seqs,masters,gcon); |
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| 193 | |
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| 194 | data = g_b_Consensus_get_sequence(gcon); |
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| 195 | |
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| 196 | GB_write_string(masters[node->index]->gbd,data); |
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| 197 | GB_write_security_write(masters[node->index]->gbd,7); |
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| 198 | |
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| 199 | g_b_delete_Consensus(gcon); |
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| 200 | free(data); |
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| 201 | |
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| 202 | (*builtMasters)++; |
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| 203 | *aborted |= GB_status(*builtMasters/(double)masterCount); |
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| 204 | } |
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| 205 | } |
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| 206 | } |
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| 207 | |
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| 208 | /* ------------------------------------- */ |
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| 209 | /* distribute master sequences */ |
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| 210 | /* ------------------------------------- */ |
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| 211 | |
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| 212 | static void subtract_sons_from_tree(GB_CTREE *node, int subtract) { |
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| 213 | while (node) { |
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| 214 | node->sons -= subtract; |
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| 215 | node = node->father; |
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| 216 | } |
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| 217 | } |
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| 218 | |
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| 219 | static int set_masters_with_sons(GB_CTREE *node, int wantedSons, int *mcount) { |
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| 220 | if (!node->is_leaf) { |
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| 221 | if (node->sons == wantedSons) { |
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| 222 | /* insert new master */ |
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| 223 | ad_assert(node->index == -1); |
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| 224 | node->index = *mcount; |
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| 225 | (*mcount)++; |
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| 226 | |
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| 227 | subtract_sons_from_tree(node->father, node->sons-1); |
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| 228 | node->sons = 1; |
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| 229 | } |
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| 230 | else if (node->sons>wantedSons) { |
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| 231 | int lMax = set_masters_with_sons(node->leftson, wantedSons, mcount); |
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| 232 | int rMax = set_masters_with_sons(node->rightson, wantedSons, mcount); |
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| 233 | |
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| 234 | int maxSons = lMax<rMax ? rMax : lMax; |
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| 235 | if (node->sons <= MAX_SEQUENCE_PER_MASTER && node->sons>maxSons) { |
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| 236 | maxSons = node->sons; |
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| 237 | } |
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| 238 | return maxSons; |
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| 239 | } |
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| 240 | } |
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| 241 | return node->sons <= MAX_SEQUENCE_PER_MASTER ? node->sons : 0; |
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| 242 | } |
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| 243 | |
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| 244 | static int maxCompressionSteps(GB_CTREE *node) { |
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| 245 | if (node->is_leaf) { |
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| 246 | return 0; |
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| 247 | } |
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| 248 | |
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| 249 | int left = maxCompressionSteps(node->leftson); |
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| 250 | int right = maxCompressionSteps(node->rightson); |
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| 251 | |
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| 252 | #if defined(SAVE_COMPRESSION_TREE_TO_DB) |
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| 253 | freeset(node->name, 0); |
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| 254 | if (node->index2 != -1) { |
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| 255 | node->name = GBS_global_string_copy("master_%03i", node->index2); |
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| 256 | } |
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| 257 | #endif /* SAVE_COMPRESSION_TREE_TO_DB */ |
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| 258 | |
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| 259 | return (left>right ? left : right) + (node->index == -1 ? 0 : 1); |
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| 260 | } |
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| 261 | |
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| 262 | static int init_indices_and_count_sons(GB_CTREE *node, int *scount, const char *ali_name) { |
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| 263 | if (node->is_leaf){ |
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| 264 | if (node->gb_node ==0 || !GBT_read_sequence(node->gb_node,(char *)ali_name)) { |
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| 265 | node->index = -1; |
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| 266 | node->sons = 0; |
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| 267 | } |
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| 268 | else { |
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| 269 | node->index = *scount; |
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| 270 | node->sons = 1; |
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| 271 | (*scount)++; |
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| 272 | } |
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| 273 | } |
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| 274 | else { |
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| 275 | node->index = -1; |
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| 276 | node->sons = |
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| 277 | init_indices_and_count_sons(node->leftson, scount, ali_name) + |
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| 278 | init_indices_and_count_sons(node->rightson, scount, ali_name); |
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| 279 | } |
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| 280 | return node->sons; |
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| 281 | } |
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| 282 | |
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| 283 | static void distribute_masters(GB_CTREE *tree, int *mcount, int *max_masters) { |
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| 284 | int wantedSons = MAX_SEQUENCE_PER_MASTER; |
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| 285 | while (wantedSons >= 2) { |
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| 286 | int maxSons = set_masters_with_sons(tree, wantedSons, mcount); |
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| 287 | wantedSons = maxSons; |
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| 288 | } |
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| 289 | ad_assert(tree->sons == 1); |
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| 290 | |
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| 291 | ad_assert(tree->index != -1); |
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| 292 | *max_masters = maxCompressionSteps(tree); |
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| 293 | } |
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| 294 | |
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| 295 | /* -------------------------------------------------------------------------------- */ |
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| 296 | |
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| 297 | static GB_INLINE long g_b_read_number2(const unsigned char **s) { |
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| 298 | unsigned int c0,c1,c2,c3,c4; |
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| 299 | c0 = (*((*s)++)); |
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| 300 | if (c0 & 0x80){ |
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| 301 | c1 = (*((*s)++)); |
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| 302 | if (c0 & 0x40) { |
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| 303 | c2 = (*((*s)++)); |
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| 304 | if (c0 & 0x20) { |
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| 305 | c3 = (*((*s)++)); |
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| 306 | if (c0 &0x10) { |
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| 307 | c4 = (*((*s)++)); |
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| 308 | return c4 | (c3<<8) | (c2<<16) | (c1<<8); |
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| 309 | }else{ |
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| 310 | return (c3) | (c2<<8 ) | (c1<<16) | ((c0 & 0x0f)<<24); |
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| 311 | } |
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| 312 | }else{ |
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| 313 | return (c2) | (c1<<8) | ((c0 & 0x1f)<<16); |
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| 314 | } |
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| 315 | }else{ |
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| 316 | return (c1) | ((c0 & 0x3f)<<8); |
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| 317 | } |
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| 318 | }else{ |
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| 319 | return c0; |
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| 320 | } |
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| 321 | } |
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| 322 | |
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| 323 | static GB_INLINE void g_b_put_number2(int i, unsigned char **s) { |
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| 324 | int j; |
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| 325 | if (i< 0x80 ){ *((*s)++)=i;return; } |
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| 326 | if (i<0x4000) { |
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| 327 | j = (i>>8) | 0x80; |
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| 328 | *((*s)++)=j; |
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| 329 | *((*s)++)=i; |
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| 330 | }else if (i<0x200000) { |
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| 331 | j = (i>>16) | 0xC0; |
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| 332 | *((*s)++)=j; |
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| 333 | j = (i>>8); |
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| 334 | *((*s)++)=j; |
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| 335 | *((*s)++)=i; |
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| 336 | } else if (i<0x10000000) { |
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| 337 | j = (i>>24) | 0xE0; |
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| 338 | *((*s)++)=j; |
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| 339 | j = (i>>16); |
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| 340 | *((*s)++)=j; |
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| 341 | j = (i>>8); |
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| 342 | *((*s)++)=j; |
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| 343 | *((*s)++)=i; |
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| 344 | } |
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| 345 | } |
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| 346 | |
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| 347 | |
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| 348 | char *gb_compress_seq_by_master(const char *master,int master_len,int master_index, |
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| 349 | GBQUARK q, const char *seq, long seq_len, |
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| 350 | long *memsize, int old_flag){ |
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| 351 | unsigned char *buffer; |
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| 352 | int rest = 0; |
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| 353 | unsigned char *d; |
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| 354 | int i,cs,cm; |
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| 355 | int last; |
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| 356 | long len = seq_len; |
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| 357 | |
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| 358 | d = buffer = (unsigned char *)GB_give_other_buffer(seq,seq_len); |
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| 359 | |
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| 360 | if (seq_len > master_len){ |
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| 361 | rest = seq_len - master_len; |
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| 362 | len = master_len; |
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| 363 | } |
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| 364 | |
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| 365 | last = -1000; /* Convert Sequence relative to Master */ |
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| 366 | for( i = len; i>0; i--){ |
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| 367 | cm = *(master++); |
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| 368 | cs = *(seq++); |
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| 369 | if (cm==cs && cs != last){ |
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| 370 | *(d++) = 0; |
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| 371 | last = 1000; |
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| 372 | }else{ |
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| 373 | *(d++) = cs; |
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| 374 | last = cs; |
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| 375 | } |
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| 376 | } |
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| 377 | for( i = rest; i>0; i--){ |
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| 378 | *(d++) = *(seq++); |
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| 379 | } |
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| 380 | |
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| 381 | { /* Append run length compression method */ |
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| 382 | unsigned char *buffer2; |
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| 383 | unsigned char *dest2; |
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| 384 | buffer2 = dest2 = (unsigned char *)GB_give_other_buffer((char *)buffer,seq_len+100); |
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| 385 | *(dest2++) = GB_COMPRESSION_SEQUENCE | old_flag; |
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| 386 | |
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| 387 | g_b_put_number2(master_index,&dest2); /* Tags */ |
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| 388 | g_b_put_number2(q,&dest2); |
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| 389 | |
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| 390 | gb_compress_equal_bytes_2((char *)buffer,seq_len,memsize,(char *)dest2); /* append runlength compressed sequences to tags */ |
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| 391 | |
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| 392 | *memsize = *memsize + (dest2-buffer2); |
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| 393 | return (char *)buffer2; |
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| 394 | } |
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| 395 | } |
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| 396 | |
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| 397 | char *gb_compress_sequence_by_master(GBDATA *gbd,const char *master,int master_len,int master_index, |
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| 398 | GBQUARK q, const char *seq, int seq_len, long *memsize) |
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| 399 | { |
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| 400 | long size; |
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| 401 | char *is = gb_compress_seq_by_master(master,master_len,master_index,q,seq,seq_len,&size,GB_COMPRESSION_LAST); |
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| 402 | char *res = gb_compress_data(gbd,0,is,size,memsize, ~(GB_COMPRESSION_DICTIONARY|GB_COMPRESSION_SORTBYTES|GB_COMPRESSION_RUNLENGTH),GB_TRUE); |
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| 403 | return res; |
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| 404 | } |
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| 405 | |
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| 406 | static GB_ERROR compress_sequence_tree(GBDATA *gb_main, GB_CTREE *tree, const char *ali_name){ |
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| 407 | GB_ERROR error = 0; |
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| 408 | long ali_len = GBT_get_alignment_len(gb_main, ali_name); |
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| 409 | int main_clock = GB_read_clock(gb_main); |
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| 410 | |
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| 411 | GB_ERROR warning = NULL; |
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| 412 | |
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| 413 | if (ali_len<0){ |
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| 414 | warning = GBS_global_string("Skipping alignment '%s' (not a valid alignment; len=%li).", ali_name, ali_len); |
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| 415 | } |
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| 416 | else { |
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| 417 | int leafcount = g_b_count_leafs(tree); |
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| 418 | if (!leafcount) { |
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| 419 | error = "Tree is empty"; |
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| 420 | } |
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| 421 | else { |
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| 422 | /* Distribute masters in tree */ |
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| 423 | int mastercount = 0; |
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| 424 | int max_compSteps = 0; // in one branch |
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| 425 | int seqcount = 0; |
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| 426 | |
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| 427 | GB_status2("Create master sequences"); |
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| 428 | GB_status(0); |
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| 429 | |
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| 430 | init_indices_and_count_sons(tree, &seqcount, ali_name); |
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| 431 | if (!seqcount) { |
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| 432 | warning = GBS_global_string("Tree contains no sequences with data in '%s'\n" |
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| 433 | "Skipping compression for this alignment", |
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| 434 | ali_name); |
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| 435 | } |
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| 436 | else { |
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| 437 | distribute_masters(tree, &mastercount, &max_compSteps); |
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| 438 | |
|---|
| 439 | #if defined(SAVE_COMPRESSION_TREE_TO_DB) |
|---|
| 440 | { |
|---|
| 441 | error = GBT_link_tree((GBT_TREE*)tree, gb_main, 0, NULL, NULL); |
|---|
| 442 | if (!error) error = GBT_write_tree(gb_main,0,"tree_compression_new",(GBT_TREE*)tree); |
|---|
| 443 | GB_information("Only generated compression tree (do NOT save DB anymore)"); |
|---|
| 444 | return error; |
|---|
| 445 | } |
|---|
| 446 | #endif /* SAVE_COMPRESSION_TREE_TO_DB */ |
|---|
| 447 | |
|---|
| 448 | // detect degenerated trees |
|---|
| 449 | { |
|---|
| 450 | int min_masters = ((seqcount-1)/MAX_SEQUENCE_PER_MASTER)+1; |
|---|
| 451 | int min_compSteps = 1; |
|---|
| 452 | { |
|---|
| 453 | int m = min_masters; |
|---|
| 454 | while (m>1) { |
|---|
| 455 | m = ((m-1)/MAX_SEQUENCE_PER_MASTER)+1; |
|---|
| 456 | min_masters += m; |
|---|
| 457 | min_compSteps++; |
|---|
| 458 | } |
|---|
| 459 | } |
|---|
| 460 | |
|---|
| 461 | int acceptable_masters = (3*min_masters)/2; // accept 50% overhead |
|---|
| 462 | int acceptable_compSteps = 11*min_compSteps; // accept 1000% overhead |
|---|
| 463 | |
|---|
| 464 | if (mastercount>acceptable_masters || max_compSteps>acceptable_compSteps) { |
|---|
| 465 | GB_warningf("Tree is ill-suited for compression (cause of deep branches)\n" |
|---|
| 466 | " Used tree Optimal tree Overhead\n" |
|---|
| 467 | "Compression steps %5i %5i %4i%% (speed)\n" |
|---|
| 468 | "Master sequences %5i %5i %4i%% (size)\n" |
|---|
| 469 | "If you like to restart with a better tree,\n" |
|---|
| 470 | "press 'Abort' to stop compression", |
|---|
| 471 | max_compSteps, min_compSteps, (100*max_compSteps)/min_compSteps-100, |
|---|
| 472 | mastercount, min_masters, (100*mastercount)/min_masters-100); |
|---|
| 473 | } |
|---|
| 474 | } |
|---|
| 475 | |
|---|
| 476 | ad_assert(mastercount>0); |
|---|
| 477 | } |
|---|
| 478 | |
|---|
| 479 | if (!warning) { |
|---|
| 480 | GBDATA *gb_master_ali = 0; |
|---|
| 481 | GBDATA *old_gb_master_ali = 0; |
|---|
| 482 | GB_Sequence *seqs = 0; |
|---|
| 483 | GB_MAIN_TYPE *Main = GB_MAIN(gb_main); |
|---|
| 484 | GBQUARK ali_quark = gb_key_2_quark(Main,ali_name); |
|---|
| 485 | unsigned long long sumorg = 0; |
|---|
| 486 | unsigned long long sumold = 0; |
|---|
| 487 | unsigned long long sumnew = 0; |
|---|
| 488 | GB_Master **masters = (GB_Master **)GB_calloc(sizeof(*masters),leafcount); |
|---|
| 489 | int si; |
|---|
| 490 | |
|---|
| 491 | { |
|---|
| 492 | char *masterfoldername = GBS_global_string_copy("%s/@master_data/@%s",GB_SYSTEM_FOLDER,ali_name); |
|---|
| 493 | old_gb_master_ali = GB_search(gb_main, masterfoldername,GB_FIND); |
|---|
| 494 | free(masterfoldername); |
|---|
| 495 | } |
|---|
| 496 | |
|---|
| 497 | // create masters |
|---|
| 498 | if (!error) { |
|---|
| 499 | { |
|---|
| 500 | char *master_data_name = GBS_global_string_copy("%s/@master_data",GB_SYSTEM_FOLDER); |
|---|
| 501 | char *master_name = GBS_global_string_copy("@%s",ali_name); |
|---|
| 502 | GBDATA *gb_master_data = gb_search(gb_main, master_data_name,GB_CREATE_CONTAINER,1); |
|---|
| 503 | |
|---|
| 504 | /* create a master container, the old is deleted as soon as all sequences are compressed by the new method*/ |
|---|
| 505 | gb_master_ali = gb_create_container(gb_master_data, master_name); |
|---|
| 506 | GB_write_security_delete(gb_master_ali,7); |
|---|
| 507 | |
|---|
| 508 | free(master_name); |
|---|
| 509 | free(master_data_name); |
|---|
| 510 | } |
|---|
| 511 | for (si = 0; si<mastercount; si++) { |
|---|
| 512 | masters[si] = (GB_Master *)GB_calloc(sizeof(GB_Master),1); |
|---|
| 513 | masters[si]->gbd = gb_create(gb_master_ali,"@master",GB_STRING); |
|---|
| 514 | } |
|---|
| 515 | seqs = (GB_Sequence *)GB_calloc(sizeof(*seqs),leafcount); |
|---|
| 516 | { |
|---|
| 517 | int builtMasters = 0; |
|---|
| 518 | int aborted = 0; |
|---|
| 519 | GB_status2("Building %i master sequences", mastercount); |
|---|
| 520 | g_b_create_master(tree,seqs,masters,mastercount,&builtMasters,-1,ali_name,ali_len, &aborted); |
|---|
| 521 | if (aborted) error = "User abort"; |
|---|
| 522 | } |
|---|
| 523 | } |
|---|
| 524 | |
|---|
| 525 | /* Compress sequences in tree */ |
|---|
| 526 | if (!error) { |
|---|
| 527 | GB_status2("Compressing %i sequences in tree", seqcount); |
|---|
| 528 | GB_status(0); |
|---|
| 529 | |
|---|
| 530 | for (si=0;si<seqcount;si++){ |
|---|
| 531 | int mi = seqs[si].master; |
|---|
| 532 | GB_Master *master = masters[mi]; |
|---|
| 533 | GBDATA *gbd = seqs[si].gbd; |
|---|
| 534 | |
|---|
| 535 | if (GB_read_clock(gbd) >= main_clock){ |
|---|
| 536 | GB_warning("A species seems to be more than once in the tree"); |
|---|
| 537 | } |
|---|
| 538 | else { |
|---|
| 539 | char *seq = GB_read_string(gbd); |
|---|
| 540 | int seq_len = GB_read_string_count(gbd); |
|---|
| 541 | long sizen = GB_read_memuse(gbd); |
|---|
| 542 | char *seqm = GB_read_string(master->gbd); |
|---|
| 543 | int master_len = GB_read_string_count(master->gbd); |
|---|
| 544 | long sizes; |
|---|
| 545 | char *ss = gb_compress_sequence_by_master(gbd,seqm,master_len,mi,ali_quark,seq,seq_len,&sizes); |
|---|
| 546 | |
|---|
| 547 | gb_write_compressed_pntr(gbd,ss,sizes,seq_len); |
|---|
| 548 | sizes = GB_read_memuse(gbd); // check real usage |
|---|
| 549 | |
|---|
| 550 | sumnew += sizes; |
|---|
| 551 | sumold += sizen; |
|---|
| 552 | sumorg += seq_len; |
|---|
| 553 | |
|---|
| 554 | free(seqm); |
|---|
| 555 | free(seq); |
|---|
| 556 | } |
|---|
| 557 | |
|---|
| 558 | if (GB_status((si+1)/(double)seqcount)) { |
|---|
| 559 | error = "User abort"; |
|---|
| 560 | break; |
|---|
| 561 | } |
|---|
| 562 | } |
|---|
| 563 | } |
|---|
| 564 | |
|---|
| 565 | /* Compress rest of sequences */ |
|---|
| 566 | if (!error) { |
|---|
| 567 | int pass; /* pass 1 : count species to compress, pass 2 : compress species */ |
|---|
| 568 | int speciesNotInTree = 0; |
|---|
| 569 | |
|---|
| 570 | GB_status2("Compressing sequences NOT in tree"); |
|---|
| 571 | GB_status(0); |
|---|
| 572 | |
|---|
| 573 | for (pass = 1; pass <= 2; ++pass) { |
|---|
| 574 | GBDATA *gb_species_data = GB_search(gb_main,"species_data",GB_CREATE_CONTAINER); |
|---|
| 575 | GBDATA *gb_species; |
|---|
| 576 | int count = 0; |
|---|
| 577 | |
|---|
| 578 | for (gb_species = GBT_first_species_rel_species_data(gb_species_data); |
|---|
| 579 | gb_species; |
|---|
| 580 | gb_species = GBT_next_species(gb_species)) |
|---|
| 581 | { |
|---|
| 582 | GBDATA *gbd = GBT_read_sequence(gb_species,ali_name); |
|---|
| 583 | |
|---|
| 584 | if(!gbd) continue; |
|---|
| 585 | if (GB_read_clock(gbd) >= main_clock) continue; /* Compress only those which are not compressed by masters */ |
|---|
| 586 | count++; |
|---|
| 587 | if (pass == 2) { |
|---|
| 588 | char *data = GB_read_string(gbd); |
|---|
| 589 | long seq_len = GB_read_string_count(gbd); |
|---|
| 590 | long size = GB_read_memuse(gbd); |
|---|
| 591 | |
|---|
| 592 | GB_write_string(gbd,""); |
|---|
| 593 | GB_write_string(gbd,data); |
|---|
| 594 | free(data); |
|---|
| 595 | |
|---|
| 596 | sumold += size; |
|---|
| 597 | |
|---|
| 598 | size = GB_read_memuse(gbd); |
|---|
| 599 | sumnew += size; |
|---|
| 600 | sumorg += seq_len; |
|---|
| 601 | |
|---|
| 602 | if (GB_status(count/(double)speciesNotInTree)) { |
|---|
| 603 | error = "User abort"; |
|---|
| 604 | break; |
|---|
| 605 | } |
|---|
| 606 | } |
|---|
| 607 | } |
|---|
| 608 | if (pass == 1) { |
|---|
| 609 | speciesNotInTree = count; |
|---|
| 610 | if (GB_status2("Compressing %i sequences NOT in tree", speciesNotInTree)) { |
|---|
| 611 | error = "User abort"; |
|---|
| 612 | break; |
|---|
| 613 | } |
|---|
| 614 | } |
|---|
| 615 | } |
|---|
| 616 | } |
|---|
| 617 | |
|---|
| 618 | if (!error) { |
|---|
| 619 | GB_status2("Compressing %i master-sequences", mastercount); |
|---|
| 620 | GB_status(0); |
|---|
| 621 | |
|---|
| 622 | /* Compress all masters */ |
|---|
| 623 | for (si=0;si<mastercount;si++){ |
|---|
| 624 | int mi = masters[si]->master; |
|---|
| 625 | |
|---|
| 626 | if (mi>0) { /* master available */ |
|---|
| 627 | GBDATA *gbd = masters[si]->gbd; |
|---|
| 628 | |
|---|
| 629 | ad_assert(mi>si); /* we don't want a recursion, because we cannot uncompress sequence compressed masters, Main->gb_master_data is wrong */ |
|---|
| 630 | |
|---|
| 631 | if (gb_read_nr(gbd) != si) { /* Check database */ |
|---|
| 632 | GB_internal_error("Sequence Compression: Master Index Conflict"); |
|---|
| 633 | error = GB_export_error("Sequence Compression: Master Index Conflict"); |
|---|
| 634 | break; |
|---|
| 635 | } |
|---|
| 636 | |
|---|
| 637 | { |
|---|
| 638 | GB_Master *master = masters[mi]; |
|---|
| 639 | char *seqm = GB_read_string(master->gbd); |
|---|
| 640 | int master_len = GB_read_string_count(master->gbd); |
|---|
| 641 | char *seq = GB_read_string(gbd); |
|---|
| 642 | int seq_len = GB_read_string_count(gbd); |
|---|
| 643 | long sizes; |
|---|
| 644 | char *ss = gb_compress_sequence_by_master(gbd,seqm,master_len,mi,ali_quark,seq,seq_len,&sizes); |
|---|
| 645 | |
|---|
| 646 | gb_write_compressed_pntr(gbd,ss,sizes,seq_len); |
|---|
| 647 | sumnew += sizes; |
|---|
| 648 | |
|---|
| 649 | free(seq); |
|---|
| 650 | free(seqm); |
|---|
| 651 | } |
|---|
| 652 | |
|---|
| 653 | if (GB_status((si+1)/(double)mastercount)) { |
|---|
| 654 | error = "User abort"; |
|---|
| 655 | break; |
|---|
| 656 | } |
|---|
| 657 | } |
|---|
| 658 | else { // count size of top master |
|---|
| 659 | GBDATA *gbd = masters[si]->gbd; |
|---|
| 660 | sumnew += GB_read_memuse(gbd); |
|---|
| 661 | } |
|---|
| 662 | } |
|---|
| 663 | |
|---|
| 664 | // count size of old master data |
|---|
| 665 | if (!error) { |
|---|
| 666 | GBDATA *gb_omaster; |
|---|
| 667 | for (gb_omaster = GB_entry(old_gb_master_ali, "@master"); |
|---|
| 668 | gb_omaster; |
|---|
| 669 | gb_omaster = GB_nextEntry(gb_omaster)) |
|---|
| 670 | { |
|---|
| 671 | long size = GB_read_memuse(gb_omaster); |
|---|
| 672 | sumold += size; |
|---|
| 673 | } |
|---|
| 674 | } |
|---|
| 675 | |
|---|
| 676 | if (!error) { |
|---|
| 677 | char *sizeOrg = strdup(GBS_readable_size(sumorg)); |
|---|
| 678 | char *sizeOld = strdup(GBS_readable_size(sumold)); |
|---|
| 679 | char *sizeNew = strdup(GBS_readable_size(sumnew)); |
|---|
| 680 | |
|---|
| 681 | GB_warningf("Alignment '%s':\n" |
|---|
| 682 | " Uncompressed data: %7s\n" |
|---|
| 683 | " Old compressed data: %7s = %6.2f%%\n" |
|---|
| 684 | " New compressed data: %7s = %6.2f%%", |
|---|
| 685 | ali_name, sizeOrg, |
|---|
| 686 | sizeOld, (100.0*sumold)/sumorg, |
|---|
| 687 | sizeNew, (100.0*sumnew)/sumorg); |
|---|
| 688 | |
|---|
| 689 | free(sizeNew); |
|---|
| 690 | free(sizeOld); |
|---|
| 691 | free(sizeOrg); |
|---|
| 692 | } |
|---|
| 693 | } |
|---|
| 694 | |
|---|
| 695 | |
|---|
| 696 | if (!error) { |
|---|
| 697 | if (old_gb_master_ali){ |
|---|
| 698 | error = GB_delete(old_gb_master_ali); |
|---|
| 699 | } |
|---|
| 700 | Main->keys[ali_quark].gb_master_ali = gb_master_ali; |
|---|
| 701 | } |
|---|
| 702 | |
|---|
| 703 | // free data |
|---|
| 704 | free(seqs); |
|---|
| 705 | for (si=0;si<mastercount;si++) free(masters[si]); |
|---|
| 706 | free(masters); |
|---|
| 707 | } |
|---|
| 708 | } |
|---|
| 709 | } |
|---|
| 710 | |
|---|
| 711 | if (warning) GB_information(warning); |
|---|
| 712 | |
|---|
| 713 | return error; |
|---|
| 714 | } |
|---|
| 715 | |
|---|
| 716 | /* Compress sequences, call only outside a transaction */ |
|---|
| 717 | GB_ERROR GBT_compress_sequence_tree2(GBDATA *gb_main, const char *tree_name, const char *ali_name){ |
|---|
| 718 | GB_ERROR error = 0; |
|---|
| 719 | GB_CTREE *ctree; |
|---|
| 720 | GB_UNDO_TYPE undo_type = GB_get_requested_undo_type(gb_main); |
|---|
| 721 | GB_MAIN_TYPE *Main = GB_MAIN(gb_main); |
|---|
| 722 | char *to_free = 0; |
|---|
| 723 | |
|---|
| 724 | if (Main->transaction>0){ |
|---|
| 725 | GB_internal_error("Internal Error: Compress Sequences called during a running transaction"); |
|---|
| 726 | return GB_export_error("Internal Error: Compress Sequences called during a running transaction"); |
|---|
| 727 | } |
|---|
| 728 | |
|---|
| 729 | GB_request_undo_type(gb_main,GB_UNDO_KILL); |
|---|
| 730 | GB_begin_transaction(gb_main); |
|---|
| 731 | GB_push_my_security(gb_main); |
|---|
| 732 | |
|---|
| 733 | if (!tree_name || !strlen(tree_name)) { |
|---|
| 734 | to_free = GBT_find_largest_tree(gb_main); |
|---|
| 735 | tree_name = to_free; |
|---|
| 736 | } |
|---|
| 737 | ctree = (GB_CTREE *)GBT_read_tree(gb_main,(char *)tree_name,-sizeof(GB_CTREE)); |
|---|
| 738 | if (!ctree) { |
|---|
| 739 | error = GB_export_errorf("Tree %s not found in database",tree_name); |
|---|
| 740 | } |
|---|
| 741 | else { |
|---|
| 742 | error = GBT_link_tree((GBT_TREE *)ctree, gb_main, GB_FALSE, 0, 0); |
|---|
| 743 | if (!error) error = compress_sequence_tree(gb_main,ctree,ali_name); |
|---|
| 744 | GBT_delete_tree((GBT_TREE *)ctree); |
|---|
| 745 | } |
|---|
| 746 | |
|---|
| 747 | GB_pop_my_security(gb_main); |
|---|
| 748 | if (error) { |
|---|
| 749 | GB_abort_transaction(gb_main); |
|---|
| 750 | } |
|---|
| 751 | else { |
|---|
| 752 | GB_commit_transaction(gb_main); |
|---|
| 753 | GB_disable_quicksave(gb_main,"Database optimized"); |
|---|
| 754 | } |
|---|
| 755 | GB_request_undo_type(gb_main,undo_type); |
|---|
| 756 | |
|---|
| 757 | if (to_free) free(to_free); |
|---|
| 758 | |
|---|
| 759 | #if defined(SAVE_COMPRESSION_TREE_TO_DB) |
|---|
| 760 | error = "fake error"; |
|---|
| 761 | #endif /* SAVE_COMPRESSION_TREE_TO_DB */ |
|---|
| 762 | |
|---|
| 763 | return error; |
|---|
| 764 | } |
|---|
| 765 | |
|---|
| 766 | void GBT_compression_test(void *dummy, GBDATA *gb_main) { |
|---|
| 767 | GB_ERROR error = GB_begin_transaction(gb_main); |
|---|
| 768 | char *ali_name = GBT_get_default_alignment(gb_main); |
|---|
| 769 | char *tree_name = GBT_read_string(gb_main, "focus/tree_name"); |
|---|
| 770 | |
|---|
| 771 | GBUSE(dummy); |
|---|
| 772 | if (!ali_name || !tree_name) error = GB_await_error(); |
|---|
| 773 | |
|---|
| 774 | error = GB_end_transaction(gb_main, error); |
|---|
| 775 | |
|---|
| 776 | if (!error) { |
|---|
| 777 | printf("Recompression data in alignment '%s' using tree '%s'\n", ali_name, tree_name); |
|---|
| 778 | error = GBT_compress_sequence_tree2(gb_main, tree_name, ali_name); |
|---|
| 779 | } |
|---|
| 780 | |
|---|
| 781 | if (error) GB_warning(error); |
|---|
| 782 | free(tree_name); |
|---|
| 783 | free(ali_name); |
|---|
| 784 | } |
|---|
| 785 | |
|---|
| 786 | |
|---|
| 787 | |
|---|
| 788 | /* ******************** Decompress Sequences ******************** */ |
|---|
| 789 | |
|---|
| 790 | char *g_b_uncompress_single_sequence_by_master(const char *s, const char *master, long size, long *new_size) { |
|---|
| 791 | const signed char *source = (signed char *)s; |
|---|
| 792 | char *dest; |
|---|
| 793 | const char *m = master; |
|---|
| 794 | unsigned int c; |
|---|
| 795 | int j; |
|---|
| 796 | int i; |
|---|
| 797 | char *buffer; |
|---|
| 798 | |
|---|
| 799 | dest = buffer = GB_give_other_buffer((char *)source,size); |
|---|
| 800 | |
|---|
| 801 | for (i=size;i;) { |
|---|
| 802 | j = *(source++); |
|---|
| 803 | if (j>0) { /* uncompressed data block */ |
|---|
| 804 | if (j>i) j=i; |
|---|
| 805 | i -= j; |
|---|
| 806 | for (;j;j--) { |
|---|
| 807 | c = *(source++); |
|---|
| 808 | if (!c) c = *m; |
|---|
| 809 | *(dest++) = c; |
|---|
| 810 | m++; |
|---|
| 811 | } |
|---|
| 812 | }else{ /* equal bytes compressed */ |
|---|
| 813 | if (!j) break; /* end symbol */ |
|---|
| 814 | if (j== -122) { |
|---|
| 815 | j = *(source++) & 0xff; |
|---|
| 816 | j |= ((*(source++)) <<8) &0xff00; |
|---|
| 817 | j = -j; |
|---|
| 818 | } |
|---|
| 819 | c = *(source++); |
|---|
| 820 | i += j; |
|---|
| 821 | if (i<0) { |
|---|
| 822 | GB_internal_error("Internal Error: Missing end in data"); |
|---|
| 823 | j += -i; |
|---|
| 824 | i = 0; |
|---|
| 825 | } |
|---|
| 826 | if (c==0) { |
|---|
| 827 | memcpy(dest, m, -j); |
|---|
| 828 | dest+= -j; |
|---|
| 829 | m+= -j; |
|---|
| 830 | } else { |
|---|
| 831 | memset(dest, c, -j); |
|---|
| 832 | dest+= -j; |
|---|
| 833 | m+= -j; |
|---|
| 834 | } |
|---|
| 835 | } |
|---|
| 836 | } |
|---|
| 837 | *(dest++) = 0; /* NULL of NULL terminated string */ |
|---|
| 838 | |
|---|
| 839 | *new_size = dest-buffer; |
|---|
| 840 | ad_assert(size == *new_size); // buffer overflow |
|---|
| 841 | |
|---|
| 842 | return buffer; |
|---|
| 843 | } |
|---|
| 844 | |
|---|
| 845 | char *gb_uncompress_by_sequence(GBDATA *gbd, const char *ss,long size, GB_ERROR *error, long *new_size) { |
|---|
| 846 | char *dest = 0; |
|---|
| 847 | |
|---|
| 848 | *error = 0; |
|---|
| 849 | if (!GB_FATHER(gbd)) { |
|---|
| 850 | *error = "Cannot uncompress this sequence: Sequence has no father"; |
|---|
| 851 | } |
|---|
| 852 | else { |
|---|
| 853 | GB_MAIN_TYPE *Main = GB_MAIN(gbd); |
|---|
| 854 | GBDATA *gb_main = (GBDATA*)Main->data; |
|---|
| 855 | char *to_free = GB_check_out_buffer(ss); /* Remove 'ss' from memory management, otherwise load_single_key_data() may destroy it */ |
|---|
| 856 | int index; |
|---|
| 857 | GBQUARK quark; |
|---|
| 858 | |
|---|
| 859 | { |
|---|
| 860 | const unsigned char *s = (const unsigned char *)ss; |
|---|
| 861 | |
|---|
| 862 | index = g_b_read_number2(&s); |
|---|
| 863 | quark = g_b_read_number2(&s); |
|---|
| 864 | |
|---|
| 865 | ss = (const char *)s; |
|---|
| 866 | } |
|---|
| 867 | |
|---|
| 868 | if (!Main->keys[quark].gb_master_ali){ |
|---|
| 869 | gb_load_single_key_data(gb_main,quark); |
|---|
| 870 | } |
|---|
| 871 | |
|---|
| 872 | if (!Main->keys[quark].gb_master_ali){ |
|---|
| 873 | *error = "Cannot uncompress this sequence: Cannot find a master sequence"; |
|---|
| 874 | } |
|---|
| 875 | else { |
|---|
| 876 | GBDATA *gb_master = gb_find_by_nr(Main->keys[quark].gb_master_ali,index); |
|---|
| 877 | if (gb_master){ |
|---|
| 878 | const char *master = GB_read_char_pntr(gb_master); /* make sure that this is not a buffer !!! */ |
|---|
| 879 | |
|---|
| 880 | ad_assert((GB_read_string_count(gb_master)+1) == size); // size mismatch between master and slave |
|---|
| 881 | dest = g_b_uncompress_single_sequence_by_master(ss, master, size, new_size); |
|---|
| 882 | } |
|---|
| 883 | else { |
|---|
| 884 | *error = GB_await_error(); |
|---|
| 885 | } |
|---|
| 886 | } |
|---|
| 887 | free(to_free); |
|---|
| 888 | } |
|---|
| 889 | |
|---|
| 890 | return dest; |
|---|
| 891 | } |
|---|