| 1 | #include "GDE_extglob.h" |
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| 2 | #include <ctime> |
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| 3 | #include <algorithm> |
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| 4 | |
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| 5 | /* |
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| 6 | Copyright (c) 1989-1990, University of Illinois board of trustees. All |
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| 7 | rights reserved. Written by Steven Smith at the Center for Prokaryote Genome |
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| 8 | Analysis. Design and implementation guidance by Dr. Gary Olsen and Dr. |
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| 9 | Carl Woese. |
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| 10 | |
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| 11 | Copyright (c) 1990,1991,1992 Steven Smith at the Harvard Genome Laboratory. |
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| 12 | all rights reserved. |
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| 13 | |
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| 14 | Copyright (c) 1993, Steven Smith, all rights reserved. |
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| 15 | |
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| 16 | */ |
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| 17 | |
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| 18 | static bool CheckType(char *seq, int len) { |
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| 19 | /* CheckType: Check base composition to see if the sequence |
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| 20 | * appears to be an amino acid sequence. |
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| 21 | */ |
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| 22 | int j, count1 = 0, count2 = 0; |
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| 23 | |
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| 24 | for (j=0; j<len; j++) { |
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| 25 | if (((seq[j]|32) < 'z') && ((seq[j]|32) > 'a')) { |
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| 26 | count1++; |
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| 27 | if (!strchr("ACGTUNacgtun", seq[j])) |
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| 28 | count2++; |
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| 29 | } |
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| 30 | } |
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| 31 | |
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| 32 | return (count2 > count1/4) ? true : false; |
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| 33 | } |
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| 34 | |
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| 35 | // ARB |
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| 36 | struct ARB_TIME { |
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| 37 | int yy; |
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| 38 | int mm; |
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| 39 | int dd; |
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| 40 | int hr; |
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| 41 | int mn; |
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| 42 | int sc; |
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| 43 | }; |
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| 44 | |
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| 45 | static void AsciiTime(void *b, char *asciitime) { |
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| 46 | ARB_TIME *a=(ARB_TIME*)b; |
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| 47 | int j; |
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| 48 | char temp[GBUFSIZ]; |
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| 49 | |
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| 50 | a->dd = 0; |
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| 51 | a->yy = 0; |
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| 52 | a->mm = 0; |
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| 53 | sscanf(asciitime, "%d%5c%d", &(a->dd), temp, &(a->yy)); |
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| 54 | temp[5] = '\0'; |
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| 55 | for (j=0; j<12; j++) |
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| 56 | if (strcmp(temp, GDEmonth[j]) == 0) |
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| 57 | a->mm = j+1; |
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| 58 | if (a->dd <0 || a->dd > 31 || a->yy < 0 || a->mm > 11) |
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| 59 | SetTime(a); |
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| 60 | return; |
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| 61 | } |
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| 62 | // ENDARB |
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| 63 | |
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| 64 | GB_ERROR ReadGen(char *filename, NA_Alignment& dataset) { |
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| 65 | GB_ERROR error = NULp; |
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| 66 | FILE *file = fopen(filename, "r"); |
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| 67 | if (!file) { |
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| 68 | error = GB_IO_error("reading", filename); |
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| 69 | } |
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| 70 | else { |
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| 71 | bool done = false; |
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| 72 | size_t len = 0; |
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| 73 | bool IS_REALLY_AA = false; |
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| 74 | char in_line[GBUFSIZ]; |
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| 75 | char c; |
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| 76 | char *buffer = NULp; |
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| 77 | char *gencomments = NULp; |
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| 78 | char fields[8][GBUFSIZ]; |
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| 79 | size_t buflen = 0; |
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| 80 | int genclen = 0; |
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| 81 | int curelem = 0; |
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| 82 | int n = 0; |
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| 83 | int start_col = -1; |
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| 84 | |
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| 85 | NA_Sequence *this_elem = NULp; |
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| 86 | |
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| 87 | for (; fgets(in_line, GBUFSIZ, file);) { |
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| 88 | if (in_line[strlen(in_line)-1] == '\n') { |
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| 89 | in_line[strlen(in_line)-1] = '\0'; |
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| 90 | } |
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| 91 | if (Find(in_line, "LOCUS")) { |
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| 92 | curelem = Arbdb_get_curelem(dataset); |
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| 93 | this_elem = &(dataset.element[curelem]); |
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| 94 | n = sscanf(in_line, "%s %s %s %s %s %s %s %s", |
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| 95 | fields[0], fields[1], fields[2], fields[3], fields[4], |
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| 96 | fields[5], fields[6], fields[7]); |
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| 97 | |
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| 98 | if (IS_REALLY_AA) { |
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| 99 | InitNASeq(this_elem, PROTEIN); |
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| 100 | } |
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| 101 | else if (Find(in_line, "DNA")) { |
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| 102 | InitNASeq(this_elem, DNA); |
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| 103 | } |
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| 104 | else if (Find(in_line, "RNA")) { |
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| 105 | InitNASeq(this_elem, RNA); |
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| 106 | } |
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| 107 | else if (Find(in_line, "MASK")) { |
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| 108 | InitNASeq(this_elem, MASK); |
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| 109 | } |
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| 110 | else if (Find(in_line, "TEXT")) { |
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| 111 | InitNASeq(this_elem, TEXT); |
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| 112 | } |
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| 113 | else if (Find(in_line, "PROT")) { |
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| 114 | InitNASeq(this_elem, PROTEIN); |
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| 115 | } |
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| 116 | else { |
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| 117 | InitNASeq(this_elem, DNA); |
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| 118 | } |
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| 119 | |
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| 120 | strcpy_truncate(this_elem->short_name, fields[1], SIZE_SHORT_NAME); |
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| 121 | AsciiTime(&(this_elem->t_stamp.origin), fields[n-1]); |
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| 122 | this_elem->attr = DEFAULT_X_ATTR; |
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| 123 | |
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| 124 | if (Find(in_line, "Circular")) { |
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| 125 | this_elem->attr |= IS_CIRCULAR; |
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| 126 | } |
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| 127 | gencomments = NULp; |
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| 128 | genclen = 0; |
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| 129 | } |
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| 130 | else if (Find(in_line, "DEFINITION")) { |
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| 131 | strcpy_truncate(this_elem->description, in_line+12, SIZE_DESCRIPTION); |
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| 132 | } |
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| 133 | else if (Find(in_line, "AUTHOR")) { |
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| 134 | strcpy_truncate(this_elem->authority, in_line+12, SIZE_AUTHORITY); |
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| 135 | } |
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| 136 | else if (Find(in_line, " ORGANISM")) { |
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| 137 | strcpy_truncate(this_elem->seq_name, in_line+12, SIZE_SEQ_NAME); |
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| 138 | } |
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| 139 | else if (Find(in_line, "ACCESSION")) { |
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| 140 | strcpy_truncate(this_elem->id, in_line+12, SIZE_ID); |
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| 141 | } |
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| 142 | else if (Find(in_line, "ORIGIN")) { |
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| 143 | done = false; |
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| 144 | len = 0; |
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| 145 | for (; !done && fgets(in_line, GBUFSIZ, file);) { |
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| 146 | if (in_line[0] != '/') { |
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| 147 | if (buflen == 0) { |
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| 148 | buflen = GBUFSIZ; |
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| 149 | ARB_calloc(buffer, buflen); |
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| 150 | } |
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| 151 | else if (len+strlen(in_line) >= buflen) { |
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| 152 | size_t new_buflen = buflen+GBUFSIZ; |
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| 153 | ARB_recalloc(buffer, buflen, new_buflen); |
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| 154 | buflen = new_buflen; |
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| 155 | } |
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| 156 | // Search for the fist column of data (whitespace-number-whitespace)data |
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| 157 | if (start_col == -1) { |
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| 158 | for (start_col=0; in_line[start_col] == ' ' || in_line[start_col] == '\t'; start_col++) ; |
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| 159 | for (start_col++; strchr("1234567890", in_line[start_col]); start_col++) ; |
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| 160 | for (start_col++; in_line[start_col] == ' ' || in_line[start_col] == '\t'; start_col++) ; |
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| 161 | } |
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| 162 | for (int j=start_col; (c = in_line[j]) != '\0'; j++) { |
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| 163 | if ((c != '\n') && ((j-start_col + 1) % 11 != 0)) { |
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| 164 | buffer[len++] = c; |
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| 165 | } |
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| 166 | } |
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| 167 | } |
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| 168 | else { |
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| 169 | AppendNA((NA_Base*)buffer, len, &(dataset.element[curelem])); |
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| 170 | for (size_t j=0; j<len; j++) buffer[j] = '\0'; |
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| 171 | len = 0; |
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| 172 | done = true; |
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| 173 | dataset.element[curelem].comments = gencomments; |
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| 174 | dataset.element[curelem].comments_len= genclen - 1; |
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| 175 | dataset.element[curelem].comments_maxlen = genclen; |
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| 176 | |
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| 177 | gencomments = NULp; |
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| 178 | genclen = 0; |
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| 179 | } |
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| 180 | } |
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| 181 | /* Test if sequence should be converted by the translation table |
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| 182 | * If it looks like a protein... |
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| 183 | */ |
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| 184 | if (dataset.element[curelem].rmatrix && !IS_REALLY_AA) { |
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| 185 | IS_REALLY_AA = CheckType((char*)dataset.element[curelem]. sequence, dataset.element[curelem].seqlen); |
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| 186 | |
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| 187 | if (!IS_REALLY_AA) |
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| 188 | Ascii2NA((char*)dataset.element[curelem].sequence, |
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| 189 | dataset.element[curelem].seqlen, |
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| 190 | dataset.element[curelem].rmatrix); |
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| 191 | else { |
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| 192 | // Force the sequence to be AA |
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| 193 | dataset.element[curelem].elementtype = PROTEIN; |
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| 194 | dataset.element[curelem].rmatrix = NULp; |
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| 195 | dataset.element[curelem].tmatrix = NULp; |
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| 196 | dataset.element[curelem].col_lut = Default_PROColor_LKUP; |
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| 197 | } |
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| 198 | } |
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| 199 | } |
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| 200 | else if (Find(in_line, "ZZZZZ")) { |
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| 201 | free(gencomments); |
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| 202 | genclen = 0; |
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| 203 | } |
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| 204 | else { |
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| 205 | if (!gencomments) { |
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| 206 | gencomments = ARB_strdup(in_line); |
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| 207 | genclen = strlen(gencomments)+1; |
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| 208 | } |
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| 209 | else { |
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| 210 | genclen += strlen(in_line)+1; |
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| 211 | ARB_realloc(gencomments, genclen); |
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| 212 | strncat(gencomments, in_line, GBUFSIZ); |
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| 213 | strncat(gencomments, "\n", GBUFSIZ); |
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| 214 | } |
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| 215 | } |
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| 216 | } |
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| 217 | free(buffer); |
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| 218 | fclose(file); |
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| 219 | } |
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| 220 | for (size_t j=0; j<dataset.numelements; j++) { |
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| 221 | dataset.maxlen = std::max(dataset.maxlen, |
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| 222 | dataset.element[j].seqlen+dataset.element[j].offset); |
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| 223 | } |
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| 224 | return error; |
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| 225 | } |
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| 226 | |
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| 227 | int WriteGen(NA_Alignment& aln, char *filename, int method) { |
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| 228 | int i; |
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| 229 | size_t j; |
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| 230 | int k; |
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| 231 | NA_Sequence *this_elem; |
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| 232 | |
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| 233 | FILE *file = fopen(filename, "w"); |
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| 234 | if (!file) { |
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| 235 | Warning("Cannot open file for output"); |
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| 236 | return 1; |
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| 237 | } |
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| 238 | |
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| 239 | for (j=0; j<aln.numelements; j++) { |
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| 240 | this_elem = &(aln.element[j]); |
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| 241 | if (method == ALL) { |
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| 242 | fprintf(file, |
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| 243 | "LOCUS %10s%8d bp %4s %10s %2d%5s%4d\n", |
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| 244 | this_elem->short_name, this_elem->seqlen+this_elem->offset, |
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| 245 | (this_elem->elementtype == DNA) ? "DNA" : |
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| 246 | (this_elem->elementtype == RNA) ? "RNA" : |
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| 247 | (this_elem->elementtype == MASK) ? "MASK" : |
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| 248 | (this_elem->elementtype == PROTEIN) ? "PROT" : "TEXT", |
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| 249 | this_elem->attr & IS_CIRCULAR ? "Circular" : "", |
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| 250 | this_elem->t_stamp.origin.dd, |
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| 251 | GDEmonth[this_elem->t_stamp.origin.mm-1], |
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| 252 | (this_elem->t_stamp.origin.yy>1900) ? this_elem->t_stamp.origin.yy : |
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| 253 | this_elem->t_stamp.origin.yy+1900); |
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| 254 | |
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| 255 | if (this_elem->description[0]) fprintf(file, "DEFINITION %s\n", this_elem->description); |
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| 256 | if (this_elem->seq_name[0]) fprintf(file, " ORGANISM %s\n", this_elem->seq_name); |
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| 257 | if (this_elem->id[0]) fprintf(file, " ACCESSION %s\n", this_elem->id); |
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| 258 | if (this_elem->authority[0]) fprintf(file, " AUTHORS %s\n", this_elem->authority); |
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| 259 | if (this_elem->comments) fprintf(file, "%s\n", this_elem->comments); |
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| 260 | |
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| 261 | fprintf(file, "ORIGIN"); |
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| 262 | |
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| 263 | if (this_elem->tmatrix) { |
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| 264 | for (i=0, k=0; k<this_elem->seqlen+this_elem->offset; k++) { |
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| 265 | if (i%60 == 0) fprintf(file, "\n%9d", i+1); |
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| 266 | if (i%10 == 0) fprintf(file, " "); |
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| 267 | fprintf(file, "%c", this_elem->tmatrix[getelem(this_elem, k)]); |
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| 268 | i++; |
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| 269 | } |
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| 270 | } |
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| 271 | else { |
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| 272 | for (i=0, k=0; k<this_elem->seqlen+this_elem->offset; k++) { |
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| 273 | if (i%60 == 0) fprintf(file, "\n%9d", i+1); |
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| 274 | if (i%10 == 0) fprintf(file, " "); |
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| 275 | fprintf(file, "%c", getelem(this_elem, k)); |
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| 276 | i++; |
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| 277 | } |
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| 278 | } |
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| 279 | fprintf(file, "\n//\n"); |
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| 280 | } |
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| 281 | } |
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| 282 | fclose(file); |
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| 283 | return 0; |
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| 284 | } |
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| 285 | |
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| 286 | |
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| 287 | void SetTime(void *b) { |
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| 288 | ARB_TIME *a=(ARB_TIME*)b; |
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| 289 | struct tm *tim; |
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| 290 | time_t clock; |
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| 291 | |
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| 292 | clock = time(NULp); |
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| 293 | tim = localtime(&clock); |
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| 294 | |
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| 295 | a->yy = tim->tm_year; |
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| 296 | a->mm = tim->tm_mon+1; |
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| 297 | a->dd = tim->tm_mday; |
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| 298 | a->hr = tim->tm_hour; |
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| 299 | a->mn = tim->tm_min; |
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| 300 | a->sc = tim->tm_sec; |
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| 301 | return; |
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| 302 | } |
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| 303 | |
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