| 1 | /*=======================================================================================*/ |
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| 2 | // |
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| 3 | // File : ED4_ProteinViewer.cxx |
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| 4 | // Purpose : Protein Viewer: Dynamical translation and display of |
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| 5 | // aminoacid sequences in the dna alignment. |
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| 6 | // Author : Yadhu Kumar (yadhu@arb-home.de) |
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| 7 | // web site : http://www.arb-home.de/ |
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| 8 | // |
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| 9 | // Copyright Department of Microbiology (Technical University Munich) |
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| 10 | // |
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| 11 | /*=======================================================================================*/ |
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| 12 | |
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| 13 | #include "ed4_ProteinViewer.hxx" |
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| 14 | #include "ed4_class.hxx" |
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| 15 | |
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| 16 | #include <awt_pro_a_nucs.hxx> |
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| 17 | #include <awt_codon_table.hxx> |
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| 18 | #include <awt_translate.hxx> |
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| 19 | #include <awt_seq_colors.hxx> |
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| 20 | #include <aw_question.hxx> |
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| 21 | #include <aw_preset.hxx> |
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| 22 | #include <aw_awars.hxx> |
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| 23 | #include <arbdbt.h> |
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| 24 | |
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| 25 | #include <iostream> |
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| 26 | |
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| 27 | using namespace std; |
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| 28 | |
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| 29 | // Definitions used |
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| 30 | #define FORWARD_STRAND 1 |
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| 31 | #define COMPLEMENTARY_STRAND 2 |
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| 32 | #define DB_FIELD_STRAND 3 |
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| 33 | |
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| 34 | #define FORWARD_STRANDS 3 |
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| 35 | #define COMPLEMENTARY_STRANDS 3 |
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| 36 | #define DB_FIELD_STRANDS 1 |
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| 37 | |
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| 38 | // typedefs |
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| 39 | typedef enum { |
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| 40 | PV_FAILED = 0, |
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| 41 | PV_SUCCESS |
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| 42 | } PV_ERROR; |
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| 43 | |
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| 44 | enum { |
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| 45 | PV_MARKED = 0, |
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| 46 | PV_SELECTED, |
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| 47 | PV_CURSOR, |
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| 48 | PV_ALL |
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| 49 | }; |
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| 50 | |
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| 51 | #define BUFFERSIZE 1000 |
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| 52 | |
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| 53 | // Global Variables |
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| 54 | extern GBDATA *GLOBAL_gb_main; |
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| 55 | |
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| 56 | static bool gTerminalsCreated = false; |
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| 57 | static int PV_AA_Terminals4Species = 0; |
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| 58 | static int gMissingTransTable = 0; |
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| 59 | static int gMissingCodonStart = 0; |
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| 60 | static bool gbWritingData = false; |
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| 61 | static int giNewAlignments = 0; |
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| 62 | |
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| 63 | static AW_repeated_question *ASKtoOverWriteData = 0; |
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| 64 | |
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| 65 | bool PV_LookForNewTerminals(AW_root *root){ |
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| 66 | bool bTerminalsFound = true; |
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| 67 | |
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| 68 | int all = root->awar(AWAR_PV_DISPLAY_ALL)->read_int(); |
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| 69 | int all_f1 = root->awar(AWAR_PROTVIEW_FORWARD_STRAND_1)->read_int(); |
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| 70 | int all_f2 = root->awar(AWAR_PROTVIEW_FORWARD_STRAND_2)->read_int(); |
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| 71 | int all_f3 = root->awar(AWAR_PROTVIEW_FORWARD_STRAND_3)->read_int(); |
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| 72 | int all_c1 = root->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_1)->read_int(); |
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| 73 | int all_c2 = root->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_2)->read_int(); |
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| 74 | int all_c3 = root->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_3)->read_int(); |
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| 75 | int all_db = root->awar(AWAR_PROTVIEW_DEFINED_FIELDS)->read_int(); |
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| 76 | |
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| 77 | int sel = root->awar(AWAR_PV_SELECTED)->read_int(); |
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| 78 | int sel_db = root->awar(AWAR_PV_SELECTED_DB)->read_int(); |
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| 79 | int sel_f1 = root->awar(AWAR_PV_SELECTED_FS_1)->read_int(); |
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| 80 | int sel_f2 = root->awar(AWAR_PV_SELECTED_FS_2)->read_int(); |
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| 81 | int sel_f3 = root->awar(AWAR_PV_SELECTED_FS_3)->read_int(); |
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| 82 | int sel_c1 = root->awar(AWAR_PV_SELECTED_CS_1)->read_int(); |
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| 83 | int sel_c2 = root->awar(AWAR_PV_SELECTED_CS_2)->read_int(); |
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| 84 | int sel_c3 = root->awar(AWAR_PV_SELECTED_CS_3)->read_int(); |
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| 85 | |
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| 86 | int mrk = root->awar(AWAR_PV_MARKED)->read_int(); |
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| 87 | int mrk_db = root->awar(AWAR_PV_MARKED_DB)->read_int(); |
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| 88 | int mrk_f1 = root->awar(AWAR_PV_MARKED_FS_1)->read_int(); |
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| 89 | int mrk_f2 = root->awar(AWAR_PV_MARKED_FS_2)->read_int(); |
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| 90 | int mrk_f3 = root->awar(AWAR_PV_MARKED_FS_3)->read_int(); |
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| 91 | int mrk_c1 = root->awar(AWAR_PV_MARKED_CS_1)->read_int(); |
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| 92 | int mrk_c2 = root->awar(AWAR_PV_MARKED_CS_2)->read_int(); |
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| 93 | int mrk_c3 = root->awar(AWAR_PV_MARKED_CS_3)->read_int(); |
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| 94 | |
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| 95 | int cur = root->awar(AWAR_PV_CURSOR)->read_int(); |
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| 96 | int cur_db = root->awar(AWAR_PV_CURSOR_DB)->read_int(); |
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| 97 | int cur_f1 = root->awar(AWAR_PV_CURSOR_FS_1)->read_int(); |
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| 98 | int cur_f2 = root->awar(AWAR_PV_CURSOR_FS_2)->read_int(); |
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| 99 | int cur_f3 = root->awar(AWAR_PV_CURSOR_FS_3)->read_int(); |
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| 100 | int cur_c1 = root->awar(AWAR_PV_CURSOR_CS_1)->read_int(); |
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| 101 | int cur_c2 = root->awar(AWAR_PV_CURSOR_CS_2)->read_int(); |
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| 102 | int cur_c3 = root->awar(AWAR_PV_CURSOR_CS_3)->read_int(); |
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| 103 | |
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| 104 | // Test whether any of the options are selected or not? |
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| 105 | if ((all && (all_f1 || all_f2 || all_f3 || all_c1 || all_c2 || all_c3 || all_db)) || |
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| 106 | (sel && (sel_db || sel_f1 || sel_f2 || sel_f3 || sel_c1 || sel_c2 || sel_c3)) || |
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| 107 | (mrk && (mrk_db || mrk_f1 || mrk_f2 || mrk_f3 || mrk_c1 || mrk_c2 || mrk_c3)) || |
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| 108 | (cur && (cur_db || cur_f1 || cur_f2 || cur_f3 || cur_c1 || cur_c2 || cur_c3))) |
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| 109 | { |
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| 110 | // if so, then test whether the terminals are created already or not? |
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| 111 | if(gTerminalsCreated) { |
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| 112 | // if yes, then set the flag to true |
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| 113 | bTerminalsFound = true; |
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| 114 | } |
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| 115 | else { |
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| 116 | //if not, then new terminals has to be created |
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| 117 | bTerminalsFound = false; |
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| 118 | } |
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| 119 | } |
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| 120 | return bTerminalsFound; |
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| 121 | } |
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| 122 | |
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| 123 | void PV_HideTerminal(ED4_AA_sequence_terminal *aaSeqTerminal) { |
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| 124 | ED4_sequence_manager *seqManager = aaSeqTerminal->get_parent(ED4_L_SEQUENCE)->to_sequence_manager(); |
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| 125 | seqManager->hide_children(); |
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| 126 | } |
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| 127 | |
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| 128 | void PV_UnHideTerminal(ED4_AA_sequence_terminal *aaSeqTerminal) { |
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| 129 | ED4_sequence_manager *seqManager = aaSeqTerminal->get_parent(ED4_L_SEQUENCE)->to_sequence_manager(); |
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| 130 | seqManager->make_children_visible(); |
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| 131 | } |
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| 132 | |
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| 133 | void PV_HideAllTerminals(){ |
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| 134 | ED4_terminal *terminal = 0; |
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| 135 | for( terminal = ED4_ROOT->root_group_man->get_first_terminal(); |
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| 136 | terminal; |
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| 137 | terminal = terminal->get_next_terminal()) |
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| 138 | { |
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| 139 | if(terminal->is_sequence_terminal()) { |
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| 140 | ED4_species_manager *speciesManager = terminal->get_parent(ED4_L_SPECIES)->to_species_manager(); |
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| 141 | if (speciesManager && !speciesManager->flag.is_consensus && !speciesManager->flag.is_SAI) { |
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| 142 | // hide all AA_Sequence terminals |
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| 143 | for(int i=0; i<PV_AA_Terminals4Species; i++) { |
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| 144 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
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| 145 | // $$$$$ sequence_terminal->sequence_info_terminal->aa_sequence_terminal $$$$$$ |
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| 146 | terminal = terminal->get_next_terminal()->get_next_terminal(); |
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| 147 | // Make sure it is AA sequence terminal |
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| 148 | if (terminal->is_aa_sequence_terminal()) { |
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| 149 | ED4_AA_sequence_terminal *aaSeqTerminal = terminal->to_aa_sequence_terminal(); |
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| 150 | PV_HideTerminal(aaSeqTerminal); |
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| 151 | } |
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| 152 | } |
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| 153 | } |
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| 154 | } |
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| 155 | } |
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| 156 | } |
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| 157 | |
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| 158 | |
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| 159 | void PV_ManageTerminalDisplay(AW_root *root, ED4_AA_sequence_terminal *aaSeqTerminal,long int DispMode){ |
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| 160 | |
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| 161 | int all, af_1,af_2,af_3,ac_1,ac_2,ac_3,adb; |
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| 162 | all = root->awar(AWAR_PV_DISPLAY_ALL)->read_int(); |
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| 163 | adb = root->awar(AWAR_PROTVIEW_DEFINED_FIELDS)->read_int(); |
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| 164 | af_1 = root->awar(AWAR_PROTVIEW_FORWARD_STRAND_1)->read_int(); |
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| 165 | af_2 = root->awar(AWAR_PROTVIEW_FORWARD_STRAND_2)->read_int(); |
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| 166 | af_3 = root->awar(AWAR_PROTVIEW_FORWARD_STRAND_3)->read_int(); |
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| 167 | ac_1 = root->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_1)->read_int(); |
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| 168 | ac_2 = root->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_2)->read_int(); |
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| 169 | ac_3 = root->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_3)->read_int(); |
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| 170 | |
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| 171 | int mrk, mf_1,mf_2,mf_3,mc_1,mc_2,mc_3,mdb; |
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| 172 | mrk = root->awar(AWAR_PV_MARKED)->read_int(); |
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| 173 | mdb = root->awar(AWAR_PV_MARKED_DB)->read_int(); |
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| 174 | mf_1 = root->awar(AWAR_PV_MARKED_FS_1)->read_int(); |
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| 175 | mf_2 = root->awar(AWAR_PV_MARKED_FS_2)->read_int(); |
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| 176 | mf_3 = root->awar(AWAR_PV_MARKED_FS_3)->read_int(); |
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| 177 | mc_1 = root->awar(AWAR_PV_MARKED_CS_1)->read_int(); |
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| 178 | mc_2 = root->awar(AWAR_PV_MARKED_CS_2)->read_int(); |
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| 179 | mc_3 = root->awar(AWAR_PV_MARKED_CS_3)->read_int(); |
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| 180 | |
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| 181 | int sel, sf_1,sf_2,sf_3,sc_1,sc_2,sc_3,sdb; |
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| 182 | sel = root->awar(AWAR_PV_SELECTED)->read_int(); |
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| 183 | sdb = root->awar(AWAR_PV_SELECTED_DB)->read_int(); |
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| 184 | sf_1 = root->awar(AWAR_PV_SELECTED_FS_1)->read_int(); |
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| 185 | sf_2 = root->awar(AWAR_PV_SELECTED_FS_2)->read_int(); |
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| 186 | sf_3 = root->awar(AWAR_PV_SELECTED_FS_3)->read_int(); |
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| 187 | sc_1 = root->awar(AWAR_PV_SELECTED_CS_1)->read_int(); |
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| 188 | sc_2 = root->awar(AWAR_PV_SELECTED_CS_2)->read_int(); |
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| 189 | sc_3 = root->awar(AWAR_PV_SELECTED_CS_3)->read_int(); |
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| 190 | |
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| 191 | int cur, cf_1,cf_2,cf_3,cc_1,cc_2,cc_3,cdb; |
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| 192 | cur = root->awar(AWAR_PV_CURSOR)->read_int(); |
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| 193 | cdb = root->awar(AWAR_PV_CURSOR_DB)->read_int(); |
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| 194 | cf_1 = root->awar(AWAR_PV_CURSOR_FS_1)->read_int(); |
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| 195 | cf_2 = root->awar(AWAR_PV_CURSOR_FS_2)->read_int(); |
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| 196 | cf_3 = root->awar(AWAR_PV_CURSOR_FS_3)->read_int(); |
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| 197 | cc_1 = root->awar(AWAR_PV_CURSOR_CS_1)->read_int(); |
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| 198 | cc_2 = root->awar(AWAR_PV_CURSOR_CS_2)->read_int(); |
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| 199 | cc_3 = root->awar(AWAR_PV_CURSOR_CS_3)->read_int(); |
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| 200 | |
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| 201 | // Get the AA sequence flag - says which strand we are in |
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| 202 | int aaStrandType = int(aaSeqTerminal->GET_aaStrandType()); |
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| 203 | // Check the display options and make visible or hide the AA seq terminal |
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| 204 | switch (aaStrandType) |
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| 205 | { |
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| 206 | case FORWARD_STRAND: |
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| 207 | { |
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| 208 | int aaStartPos = int(aaSeqTerminal->GET_aaStartPos()); |
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| 209 | switch (aaStartPos){ |
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| 210 | case 1: |
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| 211 | switch (DispMode){ |
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| 212 | case PV_ALL: (all && af_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 213 | case PV_MARKED: (mrk && mf_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 214 | case PV_SELECTED: (sel && sf_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 215 | case PV_CURSOR: (cur && cf_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 216 | } |
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| 217 | break; |
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| 218 | case 2: |
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| 219 | switch (DispMode){ |
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| 220 | case PV_ALL: (all && af_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 221 | case PV_MARKED: (mrk && mf_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 222 | case PV_SELECTED: (sel && sf_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 223 | case PV_CURSOR: (cur && cf_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 224 | } |
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| 225 | break; |
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| 226 | case 3: |
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| 227 | switch (DispMode){ |
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| 228 | case PV_ALL: (all && af_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 229 | case PV_MARKED: (mrk && mf_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 230 | case PV_SELECTED: (sel && sf_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 231 | case PV_CURSOR: (cur && cf_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 232 | } |
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| 233 | break; |
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| 234 | } |
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| 235 | } |
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| 236 | break; |
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| 237 | case COMPLEMENTARY_STRAND: |
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| 238 | { |
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| 239 | int aaStartPos = int(aaSeqTerminal->GET_aaStartPos()); |
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| 240 | switch (aaStartPos){ |
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| 241 | case 1: |
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| 242 | switch (DispMode){ |
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| 243 | case PV_ALL: (all && ac_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 244 | case PV_MARKED: (mrk && mc_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 245 | case PV_SELECTED: (sel && sc_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 246 | case PV_CURSOR: (cur && cc_1)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 247 | } |
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| 248 | break; |
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| 249 | case 2: |
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| 250 | switch (DispMode){ |
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| 251 | case PV_ALL: (all && ac_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 252 | case PV_MARKED: (mrk && mc_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 253 | case PV_SELECTED: (sel && sc_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 254 | case PV_CURSOR: (cur && cc_2)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 255 | } |
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| 256 | break; |
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| 257 | case 3: |
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| 258 | switch (DispMode){ |
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| 259 | case PV_ALL: (all && ac_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 260 | case PV_MARKED: (mrk && mc_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 261 | case PV_SELECTED: (sel && sc_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 262 | case PV_CURSOR: (cur && cc_3)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 263 | } |
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| 264 | break; |
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| 265 | } |
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| 266 | } |
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| 267 | break; |
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| 268 | case DB_FIELD_STRAND: |
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| 269 | switch (DispMode){ |
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| 270 | case PV_ALL: (all && adb)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 271 | case PV_MARKED: (mrk && mdb)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 272 | case PV_SELECTED: (sel && sdb)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 273 | case PV_CURSOR: (cur && cdb)? PV_UnHideTerminal(aaSeqTerminal): PV_HideTerminal(aaSeqTerminal); break; |
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| 274 | } |
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| 275 | break; |
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| 276 | } |
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| 277 | } |
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| 278 | |
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| 279 | void PV_ManageTerminals(AW_root *root){ |
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| 280 | |
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| 281 | // First Hide all AA_sequence Terminals |
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| 282 | PV_HideAllTerminals(); |
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| 283 | |
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| 284 | int dispAll = root->awar(AWAR_PV_DISPLAY_ALL)->read_int(); |
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| 285 | if (dispAll) |
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| 286 | { |
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| 287 | ED4_terminal *terminal = 0; |
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| 288 | for( terminal = ED4_ROOT->root_group_man->get_first_terminal(); |
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| 289 | terminal; |
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| 290 | terminal = terminal->get_next_terminal()) |
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| 291 | { |
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| 292 | if(terminal->is_sequence_terminal()) { |
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| 293 | ED4_species_manager *speciesManager = terminal->get_parent(ED4_L_SPECIES)->to_species_manager(); |
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| 294 | if (speciesManager && !speciesManager->flag.is_consensus && !speciesManager->flag.is_SAI) { |
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| 295 | // we are in the sequence terminal section of a species |
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| 296 | // walk through all the corresponding AA sequence terminals for the speecies and |
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| 297 | // hide or unhide the terminals based on the display options set by the user |
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| 298 | for(int i=0; i<PV_AA_Terminals4Species; i++) { |
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| 299 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
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| 300 | // $$$$$ sequence_terminal->sequence_info_terminal->aa_sequence_terminal $$$$$$ |
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| 301 | terminal = terminal->get_next_terminal()->get_next_terminal(); |
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| 302 | // Make sure it is AA sequence terminal |
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| 303 | if (terminal->is_aa_sequence_terminal()) { |
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| 304 | ED4_AA_sequence_terminal *aaSeqTerminal = terminal->to_aa_sequence_terminal(); |
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| 305 | PV_ManageTerminalDisplay(root, aaSeqTerminal, PV_ALL); |
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| 306 | } |
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| 307 | } |
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| 308 | } |
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| 309 | } |
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| 310 | } |
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| 311 | } |
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| 312 | |
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| 313 | int dispMarked = root->awar(AWAR_PV_MARKED)->read_int(); |
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| 314 | if (dispMarked) |
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| 315 | { |
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| 316 | GB_transaction dummy(GLOBAL_gb_main); |
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| 317 | int marked = GBT_count_marked_species(GLOBAL_gb_main); |
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| 318 | if (marked) { |
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| 319 | GBDATA *gbSpecies; |
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| 320 | for (gbSpecies = GBT_first_marked_species(GLOBAL_gb_main); |
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| 321 | gbSpecies; |
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| 322 | gbSpecies = GBT_next_marked_species(gbSpecies)) |
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| 323 | { |
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| 324 | ED4_species_name_terminal *spNameTerm = ED4_find_species_name_terminal(GBT_read_name(gbSpecies)); |
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| 325 | if (spNameTerm && spNameTerm->is_species_name_terminal()) |
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| 326 | { |
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| 327 | ED4_terminal *terminal = spNameTerm->corresponding_sequence_terminal(); |
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| 328 | for(int i=0; i<PV_AA_Terminals4Species; i++) { |
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| 329 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
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| 330 | // $$$$$ sequence_terminal->sequence_info_terminal->aa_sequence_terminal $$$$$$ |
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| 331 | terminal = terminal->get_next_terminal()->get_next_terminal(); |
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| 332 | // Make sure it is AA sequence terminal |
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| 333 | if (terminal->is_aa_sequence_terminal()) { |
|---|
| 334 | ED4_AA_sequence_terminal *aaSeqTerminal = terminal->to_aa_sequence_terminal(); |
|---|
| 335 | PV_ManageTerminalDisplay(root, aaSeqTerminal, PV_MARKED); |
|---|
| 336 | } |
|---|
| 337 | } |
|---|
| 338 | } |
|---|
| 339 | } |
|---|
| 340 | } |
|---|
| 341 | } |
|---|
| 342 | |
|---|
| 343 | int dispSelected = root->awar(AWAR_PV_SELECTED)->read_int(); |
|---|
| 344 | if (dispSelected) |
|---|
| 345 | { |
|---|
| 346 | ED4_terminal *terminal = 0; |
|---|
| 347 | for( terminal = ED4_ROOT->root_group_man->get_first_terminal(); |
|---|
| 348 | terminal; |
|---|
| 349 | terminal = terminal->get_next_terminal()) |
|---|
| 350 | { |
|---|
| 351 | if(terminal->is_sequence_terminal()) { |
|---|
| 352 | ED4_species_manager *speciesManager = terminal->get_parent(ED4_L_SPECIES)->to_species_manager(); |
|---|
| 353 | if (speciesManager && !speciesManager->flag.is_consensus && !speciesManager->flag.is_SAI) { |
|---|
| 354 | // we are in the sequence terminal section of a species |
|---|
| 355 | // walk through all the corresponding AA sequence terminals for the speecies and |
|---|
| 356 | // hide or unhide the terminals based on the display options set by the user |
|---|
| 357 | ED4_species_name_terminal *speciesNameTerm = speciesManager->search_spec_child_rek(ED4_L_SPECIES_NAME)->to_species_name_terminal(); |
|---|
| 358 | if (speciesNameTerm->flag.selected) { |
|---|
| 359 | for(int i=0; i<PV_AA_Terminals4Species; i++) { |
|---|
| 360 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
|---|
| 361 | // $$$$$ sequence_terminal->sequence_info_terminal->aa_sequence_terminal $$$$$$ |
|---|
| 362 | terminal = terminal->get_next_terminal()->get_next_terminal(); |
|---|
| 363 | // Make sure it is AA sequence terminal |
|---|
| 364 | if (terminal->is_aa_sequence_terminal()) { |
|---|
| 365 | ED4_AA_sequence_terminal *aaSeqTerminal = terminal->to_aa_sequence_terminal(); |
|---|
| 366 | PV_ManageTerminalDisplay(root, aaSeqTerminal,PV_SELECTED); |
|---|
| 367 | } |
|---|
| 368 | } |
|---|
| 369 | } |
|---|
| 370 | } |
|---|
| 371 | } |
|---|
| 372 | } |
|---|
| 373 | } |
|---|
| 374 | |
|---|
| 375 | int dispAtCursor = root->awar(AWAR_PV_CURSOR)->read_int(); |
|---|
| 376 | if (dispAtCursor) |
|---|
| 377 | { |
|---|
| 378 | // Display Only Terminals Corresponding To The Cursor Position in the multiple alignment |
|---|
| 379 | ED4_cursor *cursor = &ED4_ROOT->get_ed4w()->cursor; |
|---|
| 380 | if (cursor->owner_of_cursor) { |
|---|
| 381 | // Get The Cursor Terminal And The Corresponding Aa_Sequence Terminals And Set The Display Options |
|---|
| 382 | ED4_terminal *cursorTerminal = cursor->owner_of_cursor->to_terminal(); |
|---|
| 383 | if (!cursorTerminal->parent->parent->flag.is_consensus) { |
|---|
| 384 | for(int i=0; i<PV_AA_Terminals4Species; i++) { |
|---|
| 385 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
|---|
| 386 | // $$$$$ sequence_terminal->sequence_info_terminal->aa_sequence_terminal $$$$$$ |
|---|
| 387 | cursorTerminal = cursorTerminal->get_next_terminal()->get_next_terminal(); |
|---|
| 388 | // Make sure it is AA sequence terminal |
|---|
| 389 | if (cursorTerminal->is_aa_sequence_terminal()) { |
|---|
| 390 | ED4_AA_sequence_terminal *aaSeqTerminal = cursorTerminal->to_aa_sequence_terminal(); |
|---|
| 391 | PV_ManageTerminalDisplay(root, aaSeqTerminal, PV_CURSOR); |
|---|
| 392 | } |
|---|
| 393 | } |
|---|
| 394 | } |
|---|
| 395 | } |
|---|
| 396 | } |
|---|
| 397 | } |
|---|
| 398 | |
|---|
| 399 | void PV_RefreshWindow(AW_root *root){ |
|---|
| 400 | // Manage the terminals showing only those selected by the user |
|---|
| 401 | if(gTerminalsCreated) { |
|---|
| 402 | PV_ManageTerminals(root); |
|---|
| 403 | } |
|---|
| 404 | //Refresh all windows |
|---|
| 405 | ED4_refresh_window(0, 0, 0); |
|---|
| 406 | ED4_ROOT->refresh_all_windows(0); |
|---|
| 407 | } |
|---|
| 408 | |
|---|
| 409 | PV_ERROR PV_ComplementarySequence(char *sequence) |
|---|
| 410 | { |
|---|
| 411 | char T_or_U; |
|---|
| 412 | GB_ERROR error = GBT_determine_T_or_U(ED4_ROOT->alignment_type, &T_or_U, "complement"); |
|---|
| 413 | if (error) { |
|---|
| 414 | cout<<error<<endl; |
|---|
| 415 | return PV_FAILED; |
|---|
| 416 | } |
|---|
| 417 | |
|---|
| 418 | int seqLen = strlen(sequence); |
|---|
| 419 | char *complementarySeq = GBT_complementNucSequence((const char*) sequence, seqLen, T_or_U); |
|---|
| 420 | strcpy(sequence, complementarySeq); |
|---|
| 421 | return PV_SUCCESS; |
|---|
| 422 | } |
|---|
| 423 | |
|---|
| 424 | static void PV_WriteTranslatedSequenceToDB(ED4_AA_sequence_terminal *aaSeqTerm, char *spName) { |
|---|
| 425 | GB_begin_transaction(GLOBAL_gb_main); //open database for transaction |
|---|
| 426 | |
|---|
| 427 | GB_ERROR error = 0; |
|---|
| 428 | GBDATA *gb_species = GBT_find_species(GLOBAL_gb_main, spName); |
|---|
| 429 | char *defaultAlignment = GBT_get_default_alignment(GLOBAL_gb_main); |
|---|
| 430 | GBDATA *gb_SeqData = GBT_read_sequence(gb_species, defaultAlignment); |
|---|
| 431 | |
|---|
| 432 | char *str_SeqData = 0; |
|---|
| 433 | int len = 0; |
|---|
| 434 | if (gb_SeqData) { |
|---|
| 435 | str_SeqData = GB_read_string(gb_SeqData); |
|---|
| 436 | len = GB_read_string_count(gb_SeqData); |
|---|
| 437 | } |
|---|
| 438 | else error = "error in reading sequence from database!"; |
|---|
| 439 | |
|---|
| 440 | if (!error) { |
|---|
| 441 | GBDATA *gb_ProSeqData = 0; |
|---|
| 442 | char newAlignmentName[100]; |
|---|
| 443 | int aaStrandType = int(aaSeqTerm->GET_aaStrandType()); |
|---|
| 444 | { // If strandType is complementary strand then Get complementary sequence |
|---|
| 445 | if(aaStrandType == COMPLEMENTARY_STRAND) { |
|---|
| 446 | PV_ERROR pvError = PV_ComplementarySequence(str_SeqData); |
|---|
| 447 | if (pvError == PV_FAILED) { |
|---|
| 448 | error = "Getting complementary strand failed!!"; |
|---|
| 449 | } |
|---|
| 450 | } |
|---|
| 451 | } |
|---|
| 452 | |
|---|
| 453 | if (!error) { |
|---|
| 454 | int aaStartPos = int(aaSeqTerm->GET_aaStartPos()); |
|---|
| 455 | switch (aaStrandType) { |
|---|
| 456 | case FORWARD_STRAND: |
|---|
| 457 | sprintf(newAlignmentName, "ali_pro_ProtView_forward_start_pos_%ld", (long int) aaStartPos); break; |
|---|
| 458 | case COMPLEMENTARY_STRAND: |
|---|
| 459 | sprintf(newAlignmentName, "ali_pro_ProtView_complementary_start_pos_%ld", (long int) aaStartPos); break; |
|---|
| 460 | case DB_FIELD_STRAND: |
|---|
| 461 | sprintf(newAlignmentName, "ali_pro_ProtView_database_field_start_pos_%ld", (long int) aaStartPos); break; |
|---|
| 462 | } |
|---|
| 463 | |
|---|
| 464 | AWT_pro_a_nucs_convert(AWT_default_protein_type(), str_SeqData, len, aaStartPos-1, false, true, false, 0); |
|---|
| 465 | |
|---|
| 466 | // Create alignment data to store the translated sequence |
|---|
| 467 | GBDATA *gb_presets = GB_search(GLOBAL_gb_main, "presets", GB_CREATE_CONTAINER); |
|---|
| 468 | GBDATA *gb_alignment_exists = GB_find_string(gb_presets, "alignment_name", newAlignmentName, GB_IGNORE_CASE, down_2_level); |
|---|
| 469 | GBDATA *gb_new_alignment = 0; |
|---|
| 470 | |
|---|
| 471 | if (gb_alignment_exists) { |
|---|
| 472 | int skip_sp = 0; |
|---|
| 473 | char *question = 0; |
|---|
| 474 | GBDATA *gb_seq_data = GBT_read_sequence(gb_species, newAlignmentName); |
|---|
| 475 | if (gb_seq_data) { |
|---|
| 476 | e4_assert(ASKtoOverWriteData); |
|---|
| 477 | question = GBS_global_string_copy("\"%s\" contain data in the alignment \"%s\"!", spName, newAlignmentName); |
|---|
| 478 | skip_sp = ASKtoOverWriteData->get_answer(question, "Overwrite, Skip Species", "all", false); |
|---|
| 479 | } |
|---|
| 480 | if (skip_sp) { |
|---|
| 481 | error = GBS_global_string_copy("%s You chose to skip this Species!", question); |
|---|
| 482 | } |
|---|
| 483 | else { |
|---|
| 484 | gb_new_alignment = GBT_get_alignment(GLOBAL_gb_main,newAlignmentName); |
|---|
| 485 | if (!gb_new_alignment) error = GB_await_error(); |
|---|
| 486 | } |
|---|
| 487 | free(question); |
|---|
| 488 | } |
|---|
| 489 | else { |
|---|
| 490 | long aliLen = GBT_get_alignment_len(GLOBAL_gb_main,defaultAlignment); |
|---|
| 491 | gb_new_alignment = GBT_create_alignment(GLOBAL_gb_main,newAlignmentName,aliLen/3+1,0,1,"ami"); |
|---|
| 492 | |
|---|
| 493 | if (!gb_new_alignment) error = GB_await_error(); |
|---|
| 494 | else giNewAlignments++; |
|---|
| 495 | } |
|---|
| 496 | |
|---|
| 497 | if (!error) { |
|---|
| 498 | gb_ProSeqData = GBT_add_data(gb_species,newAlignmentName,"data", GB_STRING); |
|---|
| 499 | if (gb_ProSeqData) error = GB_write_string(gb_ProSeqData,str_SeqData); |
|---|
| 500 | else error = GB_await_error(); |
|---|
| 501 | } |
|---|
| 502 | } |
|---|
| 503 | free(str_SeqData); |
|---|
| 504 | } |
|---|
| 505 | |
|---|
| 506 | if (!error) error = GBT_check_data(GLOBAL_gb_main,0); |
|---|
| 507 | |
|---|
| 508 | GB_end_transaction_show_error(GLOBAL_gb_main, error, aw_message); |
|---|
| 509 | } |
|---|
| 510 | |
|---|
| 511 | void PV_SaveData(AW_window *aww){ |
|---|
| 512 | //IDEA: |
|---|
| 513 | //1. walk thru the AA_sequence terminals |
|---|
| 514 | //2. check the visibility status |
|---|
| 515 | //3. select only the visible terminals |
|---|
| 516 | //4. get the corresponding species name |
|---|
| 517 | //5. translate the sequence |
|---|
| 518 | //6. write to the database |
|---|
| 519 | gbWritingData = true; |
|---|
| 520 | if(gTerminalsCreated) { |
|---|
| 521 | ASKtoOverWriteData = new AW_repeated_question(); |
|---|
| 522 | |
|---|
| 523 | ED4_terminal *terminal = 0; |
|---|
| 524 | for( terminal = ED4_ROOT->root_group_man->get_first_terminal(); |
|---|
| 525 | terminal; |
|---|
| 526 | terminal = terminal->get_next_terminal()) |
|---|
| 527 | { |
|---|
| 528 | if(terminal->is_sequence_terminal()) { |
|---|
| 529 | char *speciesName = terminal->to_sequence_terminal()->species_name; |
|---|
| 530 | ED4_species_manager *speciesManager = terminal->get_parent(ED4_L_SPECIES)->to_species_manager(); |
|---|
| 531 | if (speciesManager && !speciesManager->flag.is_consensus && !speciesManager->flag.is_SAI) { |
|---|
| 532 | for(int i=0; i<PV_AA_Terminals4Species; i++) { |
|---|
| 533 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
|---|
| 534 | terminal = terminal->get_next_terminal()->get_next_terminal(); |
|---|
| 535 | // Make sure it is AA sequence terminal |
|---|
| 536 | if (terminal->is_aa_sequence_terminal()) { |
|---|
| 537 | ED4_AA_sequence_terminal *aaSeqTerminal = terminal->to_aa_sequence_terminal(); |
|---|
| 538 | ED4_base *base = (ED4_base*)aaSeqTerminal; |
|---|
| 539 | if(!base->flag.hidden) { |
|---|
| 540 | PV_WriteTranslatedSequenceToDB(aaSeqTerminal, speciesName);//, ASKtoOverWriteData); |
|---|
| 541 | } |
|---|
| 542 | } |
|---|
| 543 | } |
|---|
| 544 | } |
|---|
| 545 | } |
|---|
| 546 | } |
|---|
| 547 | if (giNewAlignments>0) { |
|---|
| 548 | char *msg = GBS_global_string_copy("Protein data saved to NEW alignments.\n%d new alignments were created and named ali_prot_ProtView_XXXX", giNewAlignments); |
|---|
| 549 | |
|---|
| 550 | aw_popup_ok(msg, false); |
|---|
| 551 | aw_message(msg); |
|---|
| 552 | |
|---|
| 553 | free(msg); |
|---|
| 554 | |
|---|
| 555 | giNewAlignments = 0; |
|---|
| 556 | } |
|---|
| 557 | } |
|---|
| 558 | gbWritingData = false; |
|---|
| 559 | AWUSE(aww); |
|---|
| 560 | } |
|---|
| 561 | |
|---|
| 562 | // This function translates gene sequence to aminoacid sequence and stores into the respective AA_Sequence_terminal |
|---|
| 563 | static void TranslateGeneToAminoAcidSequence(AW_root */*root*/, ED4_AA_sequence_terminal *seqTerm, char *speciesName, int startPos4Translation, int translationMode){ |
|---|
| 564 | GBDATA *gb_species = GBT_find_species(GLOBAL_gb_main, speciesName); |
|---|
| 565 | char *defaultAlignment = GBT_get_default_alignment(GLOBAL_gb_main); |
|---|
| 566 | GBDATA *gb_SeqData = GBT_read_sequence(gb_species, defaultAlignment); |
|---|
| 567 | |
|---|
| 568 | e4_assert(startPos4Translation>=0 && startPos4Translation<=2); |
|---|
| 569 | |
|---|
| 570 | char *str_SeqData = 0; |
|---|
| 571 | int len = 0; |
|---|
| 572 | if (gb_SeqData) { |
|---|
| 573 | str_SeqData = GB_read_string(gb_SeqData); |
|---|
| 574 | len = GB_read_string_count(gb_SeqData); |
|---|
| 575 | } |
|---|
| 576 | |
|---|
| 577 | GB_ERROR error = 0; |
|---|
| 578 | PV_ERROR pvError; |
|---|
| 579 | |
|---|
| 580 | int translationTable = AWT_default_protein_type(GLOBAL_gb_main); |
|---|
| 581 | |
|---|
| 582 | switch(translationMode) { |
|---|
| 583 | case FORWARD_STRAND: |
|---|
| 584 | break; |
|---|
| 585 | case COMPLEMENTARY_STRAND: |
|---|
| 586 | // for complementary strand - get the complementary sequence and then perform translation |
|---|
| 587 | pvError = PV_ComplementarySequence(str_SeqData); |
|---|
| 588 | if (pvError == PV_FAILED) { |
|---|
| 589 | error = "Could not get complementary strand"; |
|---|
| 590 | } |
|---|
| 591 | break; |
|---|
| 592 | case DB_FIELD_STRAND: |
|---|
| 593 | // for use database field options - fetch codon start and translation table from the respective species data |
|---|
| 594 | GBDATA *gb_translTable = GB_entry(gb_species, "transl_table"); |
|---|
| 595 | if (gb_translTable) { |
|---|
| 596 | int sp_embl_table = atoi(GB_read_char_pntr(gb_translTable)); |
|---|
| 597 | translationTable = AWT_embl_transl_table_2_arb_code_nr(sp_embl_table); |
|---|
| 598 | } |
|---|
| 599 | else { // use selected translation table as default (if 'transl_table' field is missing) |
|---|
| 600 | gMissingTransTable++; |
|---|
| 601 | } |
|---|
| 602 | GBDATA *gb_codonStart = GB_entry(gb_species, "codon_start"); |
|---|
| 603 | if (gb_codonStart) { |
|---|
| 604 | startPos4Translation = atoi(GB_read_char_pntr(gb_codonStart))-1; |
|---|
| 605 | if (startPos4Translation<0 || startPos4Translation>2) { |
|---|
| 606 | error = GB_export_errorf("'%s' has invalid codon_start entry %i (allowed: 1..3)", |
|---|
| 607 | speciesName, startPos4Translation+1); |
|---|
| 608 | break; |
|---|
| 609 | } |
|---|
| 610 | } |
|---|
| 611 | else { |
|---|
| 612 | gMissingCodonStart++; |
|---|
| 613 | startPos4Translation = 0; |
|---|
| 614 | } |
|---|
| 615 | break; |
|---|
| 616 | } |
|---|
| 617 | |
|---|
| 618 | if (!error) { |
|---|
| 619 | // do the translation: |
|---|
| 620 | AWT_pro_a_nucs_convert(translationTable, str_SeqData, len, startPos4Translation, false, true, false, 0); |
|---|
| 621 | |
|---|
| 622 | char *s = new char[len+1]; |
|---|
| 623 | int i,j; |
|---|
| 624 | char spChar = ' '; |
|---|
| 625 | { |
|---|
| 626 | int iDisplayMode = ED4_ROOT->aw_root->awar(AWAR_PROTVIEW_DISPLAY_OPTIONS)->read_int(); |
|---|
| 627 | if (iDisplayMode == PV_AA_NAME) |
|---|
| 628 | { |
|---|
| 629 | for( i=0, j=0; i<len && j<len; ) { |
|---|
| 630 | // start from the start pos of aa sequence |
|---|
| 631 | for (;i<startPos4Translation;) s[i++] = spChar; |
|---|
| 632 | char base = str_SeqData[j++]; |
|---|
| 633 | const char *AAname = 0; |
|---|
| 634 | if(base>='A' && base<='Z') { |
|---|
| 635 | AAname = AWT_get_protein_name(base); |
|---|
| 636 | } |
|---|
| 637 | else if (base=='*') { |
|---|
| 638 | AAname = "End"; |
|---|
| 639 | } |
|---|
| 640 | else { |
|---|
| 641 | for(int m =0;m<3 && i<len ;m++) |
|---|
| 642 | s[i++]=base; |
|---|
| 643 | } |
|---|
| 644 | if (AAname) { |
|---|
| 645 | for(unsigned int n =0; n<strlen(AAname) && i<len ;n++) { |
|---|
| 646 | s[i++]=AAname[n]; |
|---|
| 647 | } |
|---|
| 648 | } |
|---|
| 649 | } |
|---|
| 650 | } |
|---|
| 651 | else |
|---|
| 652 | { |
|---|
| 653 | int k = startPos4Translation+1; |
|---|
| 654 | for(i=0, j=0; i<len; i++) { |
|---|
| 655 | if((k==i) && (j<len)) { |
|---|
| 656 | s[i]=str_SeqData[j++]; |
|---|
| 657 | k+=3; |
|---|
| 658 | } |
|---|
| 659 | else |
|---|
| 660 | s[i] = spChar; |
|---|
| 661 | } |
|---|
| 662 | } |
|---|
| 663 | s[i]='\0'; // close the string |
|---|
| 664 | } |
|---|
| 665 | |
|---|
| 666 | seqTerm->SET_aaSequence_pointer(strdup(s)); |
|---|
| 667 | |
|---|
| 668 | delete s; |
|---|
| 669 | } |
|---|
| 670 | free(str_SeqData); |
|---|
| 671 | |
|---|
| 672 | if (error) aw_message(GBS_global_string("Error: %s", error)); |
|---|
| 673 | } |
|---|
| 674 | |
|---|
| 675 | void PV_PrintMissingDBentryInformation(void){ |
|---|
| 676 | if(gMissingCodonStart>0){ |
|---|
| 677 | aw_message(GBS_global_string("WARNING: 'codon start' entry not found in %d of %d species! Using 1st base as codon start...", |
|---|
| 678 | gMissingCodonStart, |
|---|
| 679 | (int)GBT_count_marked_species(GLOBAL_gb_main))); |
|---|
| 680 | gMissingCodonStart = 0; |
|---|
| 681 | } |
|---|
| 682 | if(gMissingTransTable>0){ |
|---|
| 683 | aw_message(GBS_global_string("WARNING: 'translation table' entry not found in %d of %d species! Using selected translation table as a default table...", |
|---|
| 684 | gMissingTransTable, |
|---|
| 685 | (int)GBT_count_marked_species(GLOBAL_gb_main))); |
|---|
| 686 | gMissingTransTable = 0; |
|---|
| 687 | } |
|---|
| 688 | } |
|---|
| 689 | |
|---|
| 690 | void PV_DisplayAminoAcidNames(AW_root *root) { |
|---|
| 691 | GB_transaction dummy(GLOBAL_gb_main); |
|---|
| 692 | |
|---|
| 693 | ED4_terminal *terminal = 0; |
|---|
| 694 | for( terminal = ED4_ROOT->root_group_man->get_first_terminal(); |
|---|
| 695 | terminal; |
|---|
| 696 | terminal = terminal->get_next_terminal()) |
|---|
| 697 | { |
|---|
| 698 | if(terminal->is_sequence_terminal()) { |
|---|
| 699 | ED4_sequence_terminal *seqTerminal = terminal->to_sequence_terminal(); |
|---|
| 700 | char *speciesName = seqTerminal->species_name; |
|---|
| 701 | |
|---|
| 702 | ED4_species_manager *speciesManager = terminal->get_parent(ED4_L_SPECIES)->to_species_manager(); |
|---|
| 703 | if (speciesManager && !speciesManager->flag.is_consensus && !speciesManager->flag.is_SAI) |
|---|
| 704 | { |
|---|
| 705 | // we are in the sequence terminal section of a species |
|---|
| 706 | // walk through all the corresponding AA sequence terminals for the speecies and |
|---|
| 707 | // hide or unhide the terminals based on the display options set by the user |
|---|
| 708 | for(int i=0; i<PV_AA_Terminals4Species; i++) |
|---|
| 709 | { |
|---|
| 710 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
|---|
| 711 | terminal = terminal->get_next_terminal()->get_next_terminal(); |
|---|
| 712 | // Make sure it is AA sequence terminal |
|---|
| 713 | if (terminal->is_aa_sequence_terminal()) { |
|---|
| 714 | ED4_AA_sequence_terminal *aaSeqTerminal = terminal->to_aa_sequence_terminal(); |
|---|
| 715 | // we are in AA sequence terminal |
|---|
| 716 | int aaStartPos = int(aaSeqTerminal->GET_aaStartPos()); |
|---|
| 717 | int aaStrandType = int(aaSeqTerminal->GET_aaStrandType()); |
|---|
| 718 | // retranslate the genesequence and store it to the AA_sequnce_terminal |
|---|
| 719 | TranslateGeneToAminoAcidSequence(root, aaSeqTerminal, speciesName, aaStartPos-1, aaStrandType); |
|---|
| 720 | } |
|---|
| 721 | } |
|---|
| 722 | } |
|---|
| 723 | } |
|---|
| 724 | } |
|---|
| 725 | // Print missing DB entries |
|---|
| 726 | PV_PrintMissingDBentryInformation(); |
|---|
| 727 | PV_RefreshWindow(root); |
|---|
| 728 | } |
|---|
| 729 | |
|---|
| 730 | void PV_RefreshDisplay(AW_root *root) { |
|---|
| 731 | PV_DisplayAminoAcidNames(root); |
|---|
| 732 | } |
|---|
| 733 | |
|---|
| 734 | void PV_RefreshProtViewDisplay(AW_window *aww){ |
|---|
| 735 | if(gTerminalsCreated) { |
|---|
| 736 | PV_RefreshDisplay(aww->get_root()); |
|---|
| 737 | } |
|---|
| 738 | } |
|---|
| 739 | |
|---|
| 740 | void PV_AA_SequenceUpdate_CB(GB_CB_TYPE gbtype) |
|---|
| 741 | { |
|---|
| 742 | if (gbtype==GB_CB_CHANGED && |
|---|
| 743 | gTerminalsCreated && |
|---|
| 744 | (ED4_ROOT->alignment_type == GB_AT_DNA) && |
|---|
| 745 | !gbWritingData) |
|---|
| 746 | { |
|---|
| 747 | GB_transaction dummy(GLOBAL_gb_main); |
|---|
| 748 | |
|---|
| 749 | ED4_cursor *cursor = &ED4_ROOT->get_ed4w()->cursor; |
|---|
| 750 | if (cursor->owner_of_cursor) { |
|---|
| 751 | ED4_terminal *cursorTerminal = cursor->owner_of_cursor->to_terminal(); |
|---|
| 752 | |
|---|
| 753 | if (!cursorTerminal->parent->parent->flag.is_consensus) |
|---|
| 754 | { |
|---|
| 755 | ED4_sequence_terminal *seqTerminal = cursorTerminal->to_sequence_terminal(); |
|---|
| 756 | char *speciesName = seqTerminal->species_name; |
|---|
| 757 | |
|---|
| 758 | for(int i=0; i<PV_AA_Terminals4Species; i++) |
|---|
| 759 | { |
|---|
| 760 | // get the corresponding AA_sequence_terminal skipping sequence_info terminal |
|---|
| 761 | // $$$$$ sequence_terminal->sequence_info_terminal->aa_sequence_terminal $$$$$$ |
|---|
| 762 | cursorTerminal = cursorTerminal->get_next_terminal()->get_next_terminal(); |
|---|
| 763 | // Make sure it is AA sequence terminal |
|---|
| 764 | if (cursorTerminal->is_aa_sequence_terminal()) { |
|---|
| 765 | ED4_AA_sequence_terminal *aaSeqTerminal = cursorTerminal->to_aa_sequence_terminal(); |
|---|
| 766 | // Get the AA sequence flag - says which strand we are in |
|---|
| 767 | int aaStartPos = int(aaSeqTerminal->GET_aaStartPos()); |
|---|
| 768 | int aaStrandType = int(aaSeqTerminal->GET_aaStrandType()); |
|---|
| 769 | // retranslate the genesequence and store it to the AA_sequnce_terminal |
|---|
| 770 | TranslateGeneToAminoAcidSequence(ED4_ROOT->aw_root, aaSeqTerminal, speciesName, aaStartPos-1, aaStrandType); |
|---|
| 771 | } |
|---|
| 772 | } |
|---|
| 773 | // Print missing DB entries |
|---|
| 774 | PV_PrintMissingDBentryInformation(); |
|---|
| 775 | PV_RefreshWindow(ED4_ROOT->aw_root); |
|---|
| 776 | } |
|---|
| 777 | } |
|---|
| 778 | } |
|---|
| 779 | } |
|---|
| 780 | |
|---|
| 781 | void PV_AddNewAAseqTerminals(ED4_sequence_terminal *seqTerminal, ED4_species_manager *speciesManager){ |
|---|
| 782 | int translationMode = 0; |
|---|
| 783 | char namebuffer[BUFFERSIZE]; |
|---|
| 784 | for(int i = 0; i<PV_AA_Terminals4Species; i++) |
|---|
| 785 | { |
|---|
| 786 | int count = 1; |
|---|
| 787 | int startPos = 0; |
|---|
| 788 | |
|---|
| 789 | sprintf( namebuffer, "Sequence_Manager.%ld.%d", ED4_counter, count++); |
|---|
| 790 | ED4_multi_sequence_manager *multiSeqManager = speciesManager->search_spec_child_rek(ED4_L_MULTI_SEQUENCE)->to_multi_sequence_manager(); |
|---|
| 791 | ED4_sequence_manager *new_SeqManager = new ED4_sequence_manager(namebuffer, 0, 0, 0, 0, multiSeqManager); |
|---|
| 792 | new_SeqManager->set_properties(ED4_P_MOVABLE); |
|---|
| 793 | multiSeqManager->children->append_member(new_SeqManager); |
|---|
| 794 | |
|---|
| 795 | ED4_sequence_info_terminal *new_SeqInfoTerminal = 0; |
|---|
| 796 | if (i<FORWARD_STRANDS) |
|---|
| 797 | sprintf(namebuffer, "F%d ProtienInfo_Term%ld.%d",i+1,ED4_counter, count++); |
|---|
| 798 | else if ((i-FORWARD_STRANDS)<COMPLEMENTARY_STRANDS) |
|---|
| 799 | sprintf(namebuffer, "C%dProtienInfo_Term%ld.%d",(i-FORWARD_STRANDS)+1,ED4_counter, count++); |
|---|
| 800 | else |
|---|
| 801 | sprintf(namebuffer, "DBProtienInfo_Term%ld.%d",ED4_counter, count++); |
|---|
| 802 | new_SeqInfoTerminal = new ED4_sequence_info_terminal(namebuffer, 0, 0, SEQUENCEINFOSIZE, TERMINALHEIGHT, new_SeqManager ); |
|---|
| 803 | new_SeqInfoTerminal->set_properties( (ED4_properties) (ED4_P_SELECTABLE | ED4_P_DRAGABLE | ED4_P_IS_HANDLE) ); |
|---|
| 804 | ED4_sequence_info_terminal *seqInfoTerminal = speciesManager->search_spec_child_rek(ED4_L_SEQUENCE_INFO)->to_sequence_info_terminal(); |
|---|
| 805 | new_SeqInfoTerminal->set_links( seqInfoTerminal, seqInfoTerminal ); |
|---|
| 806 | new_SeqManager->children->append_member( new_SeqInfoTerminal ); |
|---|
| 807 | |
|---|
| 808 | ED4_AA_sequence_terminal *AA_SeqTerminal = 0; |
|---|
| 809 | sprintf(namebuffer, "AA_Sequence_Term%ld.%d",ED4_counter, count++); |
|---|
| 810 | AA_SeqTerminal = new ED4_AA_sequence_terminal(namebuffer, SEQUENCEINFOSIZE, 0, 0, TERMINALHEIGHT, new_SeqManager); |
|---|
| 811 | AA_SeqTerminal->set_links( seqTerminal, seqTerminal ); |
|---|
| 812 | |
|---|
| 813 | char *speciesName = seqTerminal->species_name; |
|---|
| 814 | if (i<FORWARD_STRANDS){ |
|---|
| 815 | startPos = i; |
|---|
| 816 | translationMode = FORWARD_STRAND; |
|---|
| 817 | } |
|---|
| 818 | else if ((i-FORWARD_STRANDS)<COMPLEMENTARY_STRANDS){ |
|---|
| 819 | startPos = i-FORWARD_STRANDS; |
|---|
| 820 | translationMode = COMPLEMENTARY_STRAND; |
|---|
| 821 | } |
|---|
| 822 | else { |
|---|
| 823 | startPos = 0; |
|---|
| 824 | translationMode = DB_FIELD_STRAND; |
|---|
| 825 | } |
|---|
| 826 | TranslateGeneToAminoAcidSequence(ED4_ROOT->aw_root, AA_SeqTerminal, speciesName, startPos, translationMode); |
|---|
| 827 | AA_SeqTerminal->SET_aaSeqFlags(startPos+1,translationMode); |
|---|
| 828 | new_SeqManager->children->append_member(AA_SeqTerminal); |
|---|
| 829 | |
|---|
| 830 | ED4_counter++; |
|---|
| 831 | |
|---|
| 832 | new_SeqManager->resize_requested_by_child(); |
|---|
| 833 | } |
|---|
| 834 | } |
|---|
| 835 | |
|---|
| 836 | void PV_AddCorrespondingAAseqTerminals(ED4_species_name_terminal *spNameTerm) { |
|---|
| 837 | if(gTerminalsCreated) { |
|---|
| 838 | if (spNameTerm && spNameTerm->is_species_name_terminal()) |
|---|
| 839 | { |
|---|
| 840 | ED4_sequence_terminal *seqTerminal = spNameTerm->corresponding_sequence_terminal()->to_sequence_terminal(); |
|---|
| 841 | ED4_species_manager *speciesManager = spNameTerm->get_parent(ED4_L_SPECIES)->to_species_manager(); |
|---|
| 842 | PV_AddNewAAseqTerminals(seqTerminal,speciesManager); |
|---|
| 843 | PV_RefreshWindow(ED4_ROOT->aw_root); |
|---|
| 844 | } |
|---|
| 845 | } |
|---|
| 846 | } |
|---|
| 847 | |
|---|
| 848 | void PV_AddAAseqTerminalsToLoadedSpecies() { |
|---|
| 849 | if(gTerminalsCreated) { |
|---|
| 850 | GB_transaction dummy(GLOBAL_gb_main); |
|---|
| 851 | int marked = GBT_count_marked_species(GLOBAL_gb_main); |
|---|
| 852 | if (marked) { |
|---|
| 853 | GBDATA *gbSpecies; |
|---|
| 854 | for(gbSpecies = GBT_first_marked_species(GLOBAL_gb_main); |
|---|
| 855 | gbSpecies; |
|---|
| 856 | gbSpecies = GBT_next_marked_species(gbSpecies)) |
|---|
| 857 | { |
|---|
| 858 | const char *spName = GBT_read_name(gbSpecies); |
|---|
| 859 | cout<<marked--<<". "<<spName<<endl; |
|---|
| 860 | ED4_species_name_terminal *spNameTerm = ED4_find_species_name_terminal(spName); |
|---|
| 861 | if (spNameTerm && spNameTerm->is_species_name_terminal()) |
|---|
| 862 | { |
|---|
| 863 | ED4_terminal *terminal = spNameTerm->corresponding_sequence_terminal(); |
|---|
| 864 | // $$$ If next terminal is species_name terminal => corresponding AA seq terminal doesnt exist ==> create one $$$ |
|---|
| 865 | terminal = terminal->get_next_terminal(); |
|---|
| 866 | if (terminal->is_species_name_terminal() || terminal->is_spacer_terminal()) |
|---|
| 867 | { |
|---|
| 868 | ED4_sequence_terminal *seqTerminal = spNameTerm->corresponding_sequence_terminal()->to_sequence_terminal(); |
|---|
| 869 | ED4_species_manager *speciesManager = spNameTerm->get_parent(ED4_L_SPECIES)->to_species_manager(); |
|---|
| 870 | PV_AddNewAAseqTerminals(seqTerminal,speciesManager); |
|---|
| 871 | } |
|---|
| 872 | } |
|---|
| 873 | } |
|---|
| 874 | PV_RefreshWindow(ED4_ROOT->aw_root); |
|---|
| 875 | } |
|---|
| 876 | } |
|---|
| 877 | } |
|---|
| 878 | |
|---|
| 879 | void PV_CreateAllTerminals(AW_root *root) { |
|---|
| 880 | // 1. Get the species terminal pointer |
|---|
| 881 | // 2. Append the second terminal |
|---|
| 882 | // 3. resize the multi-species manager |
|---|
| 883 | // 4. refresh all the terminals including new appended terminals |
|---|
| 884 | |
|---|
| 885 | // Look for already created terminals, if found do nothing, otherwise, create |
|---|
| 886 | // new terminals and set gTerminalsCreated to true |
|---|
| 887 | bool bTerminalsFound = PV_LookForNewTerminals(root); |
|---|
| 888 | // if terminals are already created then do nothing exit the function |
|---|
| 889 | if(bTerminalsFound) return; |
|---|
| 890 | |
|---|
| 891 | GB_transaction dummy(GLOBAL_gb_main); |
|---|
| 892 | |
|---|
| 893 | // Number of AA sequence terminals to be created = 3 forward strands + 3 complementary strands + 1 DB field strand |
|---|
| 894 | // totally 7 strands has to be created |
|---|
| 895 | int aaTerminalsToBeCreated = FORWARD_STRANDS + COMPLEMENTARY_STRANDS + DB_FIELD_STRANDS; |
|---|
| 896 | PV_AA_Terminals4Species = aaTerminalsToBeCreated; |
|---|
| 897 | |
|---|
| 898 | ED4_terminal *terminal = 0; |
|---|
| 899 | for( terminal = ED4_ROOT->root_group_man->get_first_terminal(); |
|---|
| 900 | terminal; |
|---|
| 901 | terminal = terminal->get_next_terminal()) |
|---|
| 902 | { |
|---|
| 903 | if(terminal->is_sequence_terminal()) { |
|---|
| 904 | ED4_sequence_terminal *seqTerminal = terminal->to_sequence_terminal(); |
|---|
| 905 | if(seqTerminal->species_name) |
|---|
| 906 | { |
|---|
| 907 | ED4_species_manager *speciesManager = terminal->get_parent(ED4_L_SPECIES)->to_species_manager(); |
|---|
| 908 | if (speciesManager && !speciesManager->flag.is_consensus && !speciesManager->flag.is_SAI) |
|---|
| 909 | { |
|---|
| 910 | PV_AddNewAAseqTerminals(seqTerminal,speciesManager); |
|---|
| 911 | } |
|---|
| 912 | } |
|---|
| 913 | } |
|---|
| 914 | } |
|---|
| 915 | ED4_ROOT->main_manager->update_info.set_resize(1); |
|---|
| 916 | ED4_ROOT->main_manager->resize_requested_by_parent(); |
|---|
| 917 | |
|---|
| 918 | gTerminalsCreated = true; |
|---|
| 919 | |
|---|
| 920 | // Print missing DB entries |
|---|
| 921 | PV_PrintMissingDBentryInformation(); |
|---|
| 922 | |
|---|
| 923 | // ED4_ROOT->refresh_all_windows(0); |
|---|
| 924 | } |
|---|
| 925 | |
|---|
| 926 | void PV_CallBackFunction(AW_root *root) { |
|---|
| 927 | // Create New Terminals If Aminoacid Sequence Terminals Are Not Created |
|---|
| 928 | if (!gTerminalsCreated) { |
|---|
| 929 | // AWAR_PROTEIN_TYPE is not initialized (if called from ED4_main before creating proteinViewer window) |
|---|
| 930 | // so, initilize it here |
|---|
| 931 | root->awar_int(AWAR_PROTEIN_TYPE, AWAR_PROTEIN_TYPE_bacterial_code_index, GLOBAL_gb_main); |
|---|
| 932 | PV_CreateAllTerminals(root); |
|---|
| 933 | } |
|---|
| 934 | |
|---|
| 935 | PV_RefreshWindow(root); |
|---|
| 936 | } |
|---|
| 937 | |
|---|
| 938 | // -------------------------------------------------------------------------------- |
|---|
| 939 | // Binding callback function to the AWARS |
|---|
| 940 | // -------------------------------------------------------------------------------- |
|---|
| 941 | void PV_AddCallBacks(AW_root *awr) { |
|---|
| 942 | |
|---|
| 943 | awr->awar(AWAR_PV_DISPLAY_ALL)->add_callback(PV_CallBackFunction); |
|---|
| 944 | awr->awar(AWAR_PROTVIEW_FORWARD_STRAND_1)->add_callback(PV_CallBackFunction); |
|---|
| 945 | awr->awar(AWAR_PROTVIEW_FORWARD_STRAND_2)->add_callback(PV_CallBackFunction); |
|---|
| 946 | awr->awar(AWAR_PROTVIEW_FORWARD_STRAND_3)->add_callback(PV_CallBackFunction); |
|---|
| 947 | awr->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_1)->add_callback(PV_CallBackFunction); |
|---|
| 948 | awr->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_2)->add_callback(PV_CallBackFunction); |
|---|
| 949 | awr->awar(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_3)->add_callback(PV_CallBackFunction); |
|---|
| 950 | awr->awar(AWAR_PROTVIEW_DEFINED_FIELDS)->add_callback(PV_CallBackFunction); |
|---|
| 951 | |
|---|
| 952 | awr->awar(AWAR_PROTVIEW_DISPLAY_OPTIONS)->add_callback(PV_RefreshDisplay); |
|---|
| 953 | awr->awar(AWAR_SPECIES_NAME)->add_callback(PV_CallBackFunction); |
|---|
| 954 | |
|---|
| 955 | awr->awar(AWAR_PV_SELECTED)->add_callback(PV_CallBackFunction); |
|---|
| 956 | awr->awar(AWAR_PV_SELECTED_DB)->add_callback(PV_CallBackFunction); |
|---|
| 957 | awr->awar(AWAR_PV_SELECTED_FS_1)->add_callback(PV_CallBackFunction); |
|---|
| 958 | awr->awar(AWAR_PV_SELECTED_FS_2)->add_callback(PV_CallBackFunction); |
|---|
| 959 | awr->awar(AWAR_PV_SELECTED_FS_3)->add_callback(PV_CallBackFunction); |
|---|
| 960 | awr->awar(AWAR_PV_SELECTED_CS_1)->add_callback(PV_CallBackFunction); |
|---|
| 961 | awr->awar(AWAR_PV_SELECTED_CS_2)->add_callback(PV_CallBackFunction); |
|---|
| 962 | awr->awar(AWAR_PV_SELECTED_CS_3)->add_callback(PV_CallBackFunction); |
|---|
| 963 | |
|---|
| 964 | awr->awar(AWAR_PV_MARKED)->add_callback(PV_CallBackFunction); |
|---|
| 965 | awr->awar(AWAR_PV_MARKED_DB)->add_callback(PV_CallBackFunction); |
|---|
| 966 | awr->awar(AWAR_PV_MARKED_FS_1)->add_callback(PV_CallBackFunction); |
|---|
| 967 | awr->awar(AWAR_PV_MARKED_FS_2)->add_callback(PV_CallBackFunction); |
|---|
| 968 | awr->awar(AWAR_PV_MARKED_FS_3)->add_callback(PV_CallBackFunction); |
|---|
| 969 | awr->awar(AWAR_PV_MARKED_CS_1)->add_callback(PV_CallBackFunction); |
|---|
| 970 | awr->awar(AWAR_PV_MARKED_CS_2)->add_callback(PV_CallBackFunction); |
|---|
| 971 | awr->awar(AWAR_PV_MARKED_CS_3)->add_callback(PV_CallBackFunction); |
|---|
| 972 | |
|---|
| 973 | awr->awar(AWAR_PV_CURSOR)->add_callback(PV_CallBackFunction); |
|---|
| 974 | awr->awar(AWAR_PV_CURSOR_DB)->add_callback(PV_CallBackFunction); |
|---|
| 975 | awr->awar(AWAR_PV_CURSOR_FS_1)->add_callback(PV_CallBackFunction); |
|---|
| 976 | awr->awar(AWAR_PV_CURSOR_FS_2)->add_callback(PV_CallBackFunction); |
|---|
| 977 | awr->awar(AWAR_PV_CURSOR_FS_3)->add_callback(PV_CallBackFunction); |
|---|
| 978 | awr->awar(AWAR_PV_CURSOR_CS_1)->add_callback(PV_CallBackFunction); |
|---|
| 979 | awr->awar(AWAR_PV_CURSOR_CS_2)->add_callback(PV_CallBackFunction); |
|---|
| 980 | awr->awar(AWAR_PV_CURSOR_CS_3)->add_callback(PV_CallBackFunction); |
|---|
| 981 | } |
|---|
| 982 | |
|---|
| 983 | // -------------------------------------------------------------------------------- |
|---|
| 984 | // Creating AWARS to be used by the PROTVIEW module |
|---|
| 985 | // -------------------------------------------------------------------------------- |
|---|
| 986 | void PV_CreateAwars(AW_root *root, AW_default aw_def){ |
|---|
| 987 | |
|---|
| 988 | root->awar_int(AWAR_PV_DISPLAY_ALL, 0, aw_def); |
|---|
| 989 | |
|---|
| 990 | root->awar_int(AWAR_PROTVIEW_FORWARD_STRAND_1, 0, aw_def); |
|---|
| 991 | root->awar_int(AWAR_PROTVIEW_FORWARD_STRAND_2, 0, aw_def); |
|---|
| 992 | root->awar_int(AWAR_PROTVIEW_FORWARD_STRAND_3, 0, aw_def); |
|---|
| 993 | |
|---|
| 994 | root->awar_int(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_1, 0, aw_def); |
|---|
| 995 | root->awar_int(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_2, 0, aw_def); |
|---|
| 996 | root->awar_int(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_3, 0, aw_def); |
|---|
| 997 | |
|---|
| 998 | root->awar_int(AWAR_PROTVIEW_DEFINED_FIELDS, 0, aw_def); |
|---|
| 999 | root->awar_int(AWAR_PROTVIEW_DISPLAY_OPTIONS, 0, aw_def); |
|---|
| 1000 | |
|---|
| 1001 | root->awar_int(AWAR_PV_SELECTED, 0, aw_def); |
|---|
| 1002 | root->awar_int(AWAR_PV_SELECTED_DB, 0, aw_def); |
|---|
| 1003 | root->awar_int(AWAR_PV_SELECTED_FS_1, 0, aw_def); |
|---|
| 1004 | root->awar_int(AWAR_PV_SELECTED_FS_2, 0, aw_def); |
|---|
| 1005 | root->awar_int(AWAR_PV_SELECTED_FS_3, 0, aw_def); |
|---|
| 1006 | root->awar_int(AWAR_PV_SELECTED_CS_1, 0, aw_def); |
|---|
| 1007 | root->awar_int(AWAR_PV_SELECTED_CS_2, 0, aw_def); |
|---|
| 1008 | root->awar_int(AWAR_PV_SELECTED_CS_3, 0, aw_def); |
|---|
| 1009 | |
|---|
| 1010 | root->awar_int(AWAR_PV_MARKED, 0, aw_def); |
|---|
| 1011 | root->awar_int(AWAR_PV_MARKED_DB, 0, aw_def); |
|---|
| 1012 | root->awar_int(AWAR_PV_MARKED_FS_1, 0, aw_def); |
|---|
| 1013 | root->awar_int(AWAR_PV_MARKED_FS_2, 0, aw_def); |
|---|
| 1014 | root->awar_int(AWAR_PV_MARKED_FS_3, 0, aw_def); |
|---|
| 1015 | root->awar_int(AWAR_PV_MARKED_CS_1, 0, aw_def); |
|---|
| 1016 | root->awar_int(AWAR_PV_MARKED_CS_2, 0, aw_def); |
|---|
| 1017 | root->awar_int(AWAR_PV_MARKED_CS_3, 0, aw_def); |
|---|
| 1018 | |
|---|
| 1019 | root->awar_int(AWAR_PV_CURSOR, 0, aw_def); |
|---|
| 1020 | root->awar_int(AWAR_PV_CURSOR_DB, 0, aw_def); |
|---|
| 1021 | root->awar_int(AWAR_PV_CURSOR_FS_1, 0, aw_def); |
|---|
| 1022 | root->awar_int(AWAR_PV_CURSOR_FS_2, 0, aw_def); |
|---|
| 1023 | root->awar_int(AWAR_PV_CURSOR_FS_3, 0, aw_def); |
|---|
| 1024 | root->awar_int(AWAR_PV_CURSOR_CS_1, 0, aw_def); |
|---|
| 1025 | root->awar_int(AWAR_PV_CURSOR_CS_2, 0, aw_def); |
|---|
| 1026 | root->awar_int(AWAR_PV_CURSOR_CS_3, 0, aw_def); |
|---|
| 1027 | } |
|---|
| 1028 | |
|---|
| 1029 | AW_window *ED4_CreateProteinViewer_window(AW_root *aw_root) { |
|---|
| 1030 | GB_transaction dummy(GLOBAL_gb_main); |
|---|
| 1031 | |
|---|
| 1032 | static AW_window_simple *aws = 0; |
|---|
| 1033 | if (aws) return aws; |
|---|
| 1034 | |
|---|
| 1035 | aws = new AW_window_simple; |
|---|
| 1036 | |
|---|
| 1037 | aws->init( aw_root, "PROTEIN_VIEWER", "Protein Viewer"); |
|---|
| 1038 | aws->load_xfig("proteinViewer.fig"); |
|---|
| 1039 | |
|---|
| 1040 | aws->at("refresh"); |
|---|
| 1041 | aws->callback(PV_RefreshProtViewDisplay); |
|---|
| 1042 | aws->button_length(0); |
|---|
| 1043 | aws->create_button("REFRESH","#refresh_text.xpm"); |
|---|
| 1044 | |
|---|
| 1045 | aws->callback( AW_POPUP_HELP,(AW_CL)"proteinViewer.hlp"); |
|---|
| 1046 | aws->at("help"); |
|---|
| 1047 | aws->button_length(0); |
|---|
| 1048 | aws->create_button("HELP","#help_text.xpm"); |
|---|
| 1049 | |
|---|
| 1050 | aws->at("close"); |
|---|
| 1051 | aws->callback((AW_CB0)AW_POPDOWN); |
|---|
| 1052 | aws->button_length(0); |
|---|
| 1053 | aws->create_button("CLOSE","#close_text.xpm"); |
|---|
| 1054 | |
|---|
| 1055 | { |
|---|
| 1056 | aw_root->awar_int(AWAR_PROTEIN_TYPE, AWAR_PROTEIN_TYPE_bacterial_code_index, GLOBAL_gb_main); |
|---|
| 1057 | aws->at("table"); |
|---|
| 1058 | aws->create_option_menu(AWAR_PROTEIN_TYPE); |
|---|
| 1059 | for (int code_nr=0; code_nr<AWT_CODON_TABLES; code_nr++) { |
|---|
| 1060 | aws->insert_option(AWT_get_codon_code_name(code_nr), "", code_nr); |
|---|
| 1061 | } |
|---|
| 1062 | aws->update_option_menu(); |
|---|
| 1063 | |
|---|
| 1064 | aws->at("all"); |
|---|
| 1065 | aws->create_toggle(AWAR_PV_DISPLAY_ALL); |
|---|
| 1066 | |
|---|
| 1067 | aws->at("f1"); |
|---|
| 1068 | aws->create_toggle(AWAR_PROTVIEW_FORWARD_STRAND_1); |
|---|
| 1069 | |
|---|
| 1070 | aws->at("f2"); |
|---|
| 1071 | aws->create_toggle(AWAR_PROTVIEW_FORWARD_STRAND_2); |
|---|
| 1072 | |
|---|
| 1073 | aws->at("f3"); |
|---|
| 1074 | aws->create_toggle(AWAR_PROTVIEW_FORWARD_STRAND_3); |
|---|
| 1075 | |
|---|
| 1076 | aws->at("c1"); |
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| 1077 | aws->create_toggle(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_1); |
|---|
| 1078 | |
|---|
| 1079 | aws->at("c2"); |
|---|
| 1080 | aws->create_toggle(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_2); |
|---|
| 1081 | |
|---|
| 1082 | aws->at("c3"); |
|---|
| 1083 | aws->create_toggle(AWAR_PROTVIEW_COMPLEMENTARY_STRAND_3); |
|---|
| 1084 | |
|---|
| 1085 | aws->at("defined"); |
|---|
| 1086 | aws->create_toggle(AWAR_PROTVIEW_DEFINED_FIELDS); |
|---|
| 1087 | |
|---|
| 1088 | aws->at("dispOption"); |
|---|
| 1089 | aws->create_toggle_field(AWAR_PROTVIEW_DISPLAY_OPTIONS,0); |
|---|
| 1090 | aws->insert_toggle("Single Letter Code", "S", 0); |
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| 1091 | aws->insert_toggle("Triple Letter Code", "T", 1); |
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| 1092 | aws->insert_toggle("Colored Box", "B", 2); |
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| 1093 | aws->update_toggle_field(); |
|---|
| 1094 | |
|---|
| 1095 | aws->at("colMaps"); |
|---|
| 1096 | aws->callback(AW_POPUP,(AW_CL)create_seq_colors_window, (AW_CL)ED4_ROOT->sequence_colors); |
|---|
| 1097 | aws->button_length(0); |
|---|
| 1098 | aws->create_button("COLORMAPS","#colorMaps.xpm"); |
|---|
| 1099 | |
|---|
| 1100 | aws->at("colors"); |
|---|
| 1101 | aws->callback(AW_POPUP,(AW_CL)AW_create_gc_window, (AW_CL)ED4_ROOT->aw_gc_manager); |
|---|
| 1102 | aws->button_length(0); |
|---|
| 1103 | aws->create_button("COLORS","#colors.xpm"); |
|---|
| 1104 | |
|---|
| 1105 | { |
|---|
| 1106 | aws->at("sel"); aws->create_toggle(AWAR_PV_SELECTED); |
|---|
| 1107 | aws->at("sf1"); aws->create_toggle(AWAR_PV_SELECTED_FS_1); |
|---|
| 1108 | aws->at("sf2"); aws->create_toggle(AWAR_PV_SELECTED_FS_2); |
|---|
| 1109 | aws->at("sf3"); aws->create_toggle(AWAR_PV_SELECTED_FS_3); |
|---|
| 1110 | aws->at("sc1"); aws->create_toggle(AWAR_PV_SELECTED_CS_1); |
|---|
| 1111 | aws->at("sc2"); aws->create_toggle(AWAR_PV_SELECTED_CS_2); |
|---|
| 1112 | aws->at("sc3"); aws->create_toggle(AWAR_PV_SELECTED_CS_3); |
|---|
| 1113 | aws->at("sdb"); aws->create_toggle(AWAR_PV_SELECTED_DB); |
|---|
| 1114 | |
|---|
| 1115 | aws->at("mrk"); aws->create_toggle(AWAR_PV_MARKED); |
|---|
| 1116 | aws->at("mf1"); aws->create_toggle(AWAR_PV_MARKED_FS_1); |
|---|
| 1117 | aws->at("mf2"); aws->create_toggle(AWAR_PV_MARKED_FS_2); |
|---|
| 1118 | aws->at("mf3"); aws->create_toggle(AWAR_PV_MARKED_FS_3); |
|---|
| 1119 | aws->at("mc1"); aws->create_toggle(AWAR_PV_MARKED_CS_1); |
|---|
| 1120 | aws->at("mc2"); aws->create_toggle(AWAR_PV_MARKED_CS_2); |
|---|
| 1121 | aws->at("mc3"); aws->create_toggle(AWAR_PV_MARKED_CS_3); |
|---|
| 1122 | aws->at("mdb"); aws->create_toggle(AWAR_PV_MARKED_DB); |
|---|
| 1123 | |
|---|
| 1124 | aws->at("cur"); aws->create_toggle(AWAR_PV_CURSOR); |
|---|
| 1125 | aws->at("cf1"); aws->create_toggle(AWAR_PV_CURSOR_FS_1); |
|---|
| 1126 | aws->at("cf2"); aws->create_toggle(AWAR_PV_CURSOR_FS_2); |
|---|
| 1127 | aws->at("cf3"); aws->create_toggle(AWAR_PV_CURSOR_FS_3); |
|---|
| 1128 | aws->at("cc1"); aws->create_toggle(AWAR_PV_CURSOR_CS_1); |
|---|
| 1129 | aws->at("cc2"); aws->create_toggle(AWAR_PV_CURSOR_CS_2); |
|---|
| 1130 | aws->at("cc3"); aws->create_toggle(AWAR_PV_CURSOR_CS_3); |
|---|
| 1131 | aws->at("cdb"); aws->create_toggle(AWAR_PV_CURSOR_DB); |
|---|
| 1132 | } |
|---|
| 1133 | |
|---|
| 1134 | aws->at("save"); |
|---|
| 1135 | aws->callback(PV_SaveData); |
|---|
| 1136 | aws->button_length(5); |
|---|
| 1137 | aws->create_button("SAVE","#save.xpm"); |
|---|
| 1138 | } |
|---|
| 1139 | |
|---|
| 1140 | // binding callback function to the AWARS |
|---|
| 1141 | PV_AddCallBacks(aw_root); |
|---|
| 1142 | |
|---|
| 1143 | // Create All Terminals |
|---|
| 1144 | PV_CreateAllTerminals(aw_root); |
|---|
| 1145 | |
|---|
| 1146 | aws->show(); |
|---|
| 1147 | |
|---|
| 1148 | return (AW_window *)aws; |
|---|
| 1149 | } |
|---|
| 1150 | |
|---|
| 1151 | #undef BUFFERSIZE |
|---|