| 1 | #include <stdio.h> |
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| 2 | #include <stdlib.h> |
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| 3 | #include <string.h> |
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| 4 | // #include <malloc.h> |
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| 5 | #include <iostream> |
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| 6 | #include <limits.h> |
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| 7 | #include <arbdb.h> |
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| 8 | #include <arbdbt.h> |
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| 9 | |
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| 10 | #include <aw_root.hxx> |
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| 11 | #include <aw_device.hxx> |
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| 12 | #include <aw_window.hxx> |
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| 13 | #include <aw_preset.hxx> |
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| 14 | #include <aw_awars.hxx> |
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| 15 | #include <awt_canvas.hxx> |
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| 16 | #include <awt.hxx> |
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| 17 | #include <awt_nds.hxx> |
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| 18 | |
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| 19 | #include <awt_tree.hxx> |
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| 20 | #include <awt_dtree.hxx> |
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| 21 | #include <awt_tree_cb.hxx> |
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| 22 | #include <awt_sel_boxes.hxx> |
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| 23 | |
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| 24 | #include <awt_csp.hxx> |
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| 25 | |
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| 26 | #include "AP_buffer.hxx" |
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| 27 | #include "parsimony.hxx" |
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| 28 | #include "ap_tree_nlen.hxx" |
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| 29 | #include "pars_main.hxx" |
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| 30 | #include "pars_dtree.hxx" |
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| 31 | |
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| 32 | #include <list> |
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| 33 | |
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| 34 | #if defined(DEBUG) |
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| 35 | # define TEST_FUNCTIONS |
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| 36 | #endif // DEBUG |
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| 37 | |
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| 38 | |
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| 39 | using namespace std; |
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| 40 | |
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| 41 | AW_HEADER_MAIN |
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| 42 | |
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| 43 | GBDATA *GLOBAL_gb_main; // global gb_main for arb_pars |
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| 44 | NT_global *GLOBAL_NT; |
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| 45 | |
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| 46 | // waaah more globals :( |
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| 47 | AP_main *ap_main; |
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| 48 | AWT_csp *awt_csp = 0; |
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| 49 | |
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| 50 | AW_window *create_kernighan_window(AW_root *aw_root); |
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| 51 | |
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| 52 | static void pars_export_tree(void){ |
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| 53 | // GB_ERROR error = GLOBAL_NT->tree->tree_root->AP_tree::saveTree(); |
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| 54 | GB_ERROR error = GLOBAL_NT->tree->save(0, 0, 0, 0); |
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| 55 | if (error) aw_message(error); |
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| 56 | } |
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| 57 | |
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| 58 | ATTRIBUTED(__ATTR__NORETURN, static void pars_exit(AW_window *aww)) { |
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| 59 | aww->get_root()->unlink_awars_from_DB(GLOBAL_gb_main); |
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| 60 | #if defined(DEBUG) |
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| 61 | AWT_browser_forget_db(GLOBAL_gb_main); |
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| 62 | #endif // DEBUG |
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| 63 | GB_close(GLOBAL_gb_main); |
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| 64 | exit(0); |
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| 65 | } |
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| 66 | |
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| 67 | void PARS_export_cb(AW_window *aww, AWT_canvas *, AW_CL mode){ |
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| 68 | if (mode &1){ // export tree |
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| 69 | pars_export_tree(); |
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| 70 | } |
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| 71 | if (mode &2) { |
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| 72 | //quit |
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| 73 | pars_exit(aww); |
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| 74 | } |
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| 75 | } |
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| 76 | |
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| 77 | void AP_user_push_cb(AW_window *aww, AWT_canvas *) |
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| 78 | { |
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| 79 | ap_main->user_push(); |
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| 80 | aww->get_root()->awar(AWAR_STACKPOINTER)->write_int(ap_main->user_push_counter); |
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| 81 | } |
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| 82 | |
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| 83 | void AP_user_pop_cb(AW_window *aww,AWT_canvas *ntw) |
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| 84 | { |
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| 85 | if (ap_main->user_push_counter<=0) { |
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| 86 | aw_message("No tree on stack."); |
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| 87 | return; |
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| 88 | } |
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| 89 | ap_main->user_pop(); |
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| 90 | (*ap_main->tree_root)->compute_tree(GLOBAL_gb_main); |
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| 91 | ntw->zoom_reset(); |
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| 92 | ntw->refresh(); |
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| 93 | (*ap_main->tree_root)->test_tree(); |
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| 94 | aww->get_root()->awar(AWAR_STACKPOINTER)->write_int(ap_main->user_push_counter); |
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| 95 | pars_export_tree(); |
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| 96 | |
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| 97 | if (ap_main->user_push_counter <= 0) { // last tree was popped => push again |
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| 98 | AP_user_push_cb(aww, ntw); |
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| 99 | } |
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| 100 | } |
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| 101 | |
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| 102 | struct InsertData { |
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| 103 | AP_BOOL quick_add_flag; |
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| 104 | AP_BOOL singlestatus; // update status for single species addition |
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| 105 | int abort_flag; |
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| 106 | long maxspecies; |
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| 107 | long currentspecies; |
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| 108 | |
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| 109 | InsertData(AP_BOOL quick) |
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| 110 | : quick_add_flag(quick) |
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| 111 | , singlestatus(AP_FALSE) |
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| 112 | , abort_flag(AP_FALSE) |
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| 113 | , maxspecies(0) |
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| 114 | , currentspecies(0) |
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| 115 | { |
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| 116 | } |
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| 117 | }; |
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| 118 | |
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| 119 | static long insert_species_in_tree_test(const char *key,long val, void *cd_isits) { |
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| 120 | if (!val) return val; |
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| 121 | |
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| 122 | InsertData *isits = (InsertData*)cd_isits; |
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| 123 | if (isits->abort_flag) return val; |
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| 124 | |
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| 125 | AP_tree *tree = (*ap_main->tree_root); |
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| 126 | GBDATA *gb_node = (GBDATA *)val; |
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| 127 | |
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| 128 | GB_begin_transaction(GLOBAL_gb_main); |
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| 129 | |
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| 130 | GBDATA *gb_data = GBT_read_sequence(gb_node,ap_main->use); |
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| 131 | if (!gb_data) |
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| 132 | { |
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| 133 | sprintf(AW_ERROR_BUFFER,"Warning Species '%s' has no sequence '%s'", |
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| 134 | key,ap_main->use); |
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| 135 | aw_message(); |
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| 136 | GB_commit_transaction(GLOBAL_gb_main); |
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| 137 | return val; |
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| 138 | } |
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| 139 | |
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| 140 | AP_tree *leaf = tree->dup(); |
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| 141 | leaf->gb_node = gb_node; |
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| 142 | leaf->name = strdup(key); |
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| 143 | leaf->is_leaf = GB_TRUE; |
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| 144 | |
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| 145 | leaf->sequence = leaf->tree_root->sequence_template->dup(); |
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| 146 | leaf->sequence->set(GB_read_char_pntr(gb_data)); |
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| 147 | GB_commit_transaction (GLOBAL_gb_main); |
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| 148 | |
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| 149 | if (leaf->sequence->real_len() < MIN_SEQUENCE_LENGTH) |
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| 150 | { |
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| 151 | sprintf(AW_ERROR_BUFFER, |
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| 152 | "Species %s has too short sequence (%i, minimum is %i)", |
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| 153 | key, |
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| 154 | (int)leaf->sequence->real_len(), |
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| 155 | MIN_SEQUENCE_LENGTH); |
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| 156 | aw_message(); |
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| 157 | delete leaf; |
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| 158 | return val; |
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| 159 | } |
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| 160 | |
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| 161 | if (isits->singlestatus) { |
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| 162 | sprintf(AW_ERROR_BUFFER, |
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| 163 | "Inserting Species %s (%li:%li)", |
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| 164 | key, |
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| 165 | ++isits->currentspecies, |
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| 166 | isits->maxspecies); |
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| 167 | aw_openstatus(AW_ERROR_BUFFER); |
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| 168 | } |
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| 169 | else { |
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| 170 | isits->abort_flag = aw_status(++isits->currentspecies/(double)isits->maxspecies); |
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| 171 | } |
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| 172 | |
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| 173 | { |
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| 174 | AP_FLOAT best_val = 9999999999999.0; |
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| 175 | AP_FLOAT this_val; |
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| 176 | int cnt = 0; |
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| 177 | |
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| 178 | while (cnt<2) { |
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| 179 | char buf[200]; |
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| 180 | |
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| 181 | sprintf(buf,"Pre-optimize (pars=%f)",best_val); |
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| 182 | |
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| 183 | aw_status(buf); |
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| 184 | this_val = rootEdge()->nni_rek(AP_FALSE,isits->abort_flag,-1); |
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| 185 | if (this_val<best_val) { |
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| 186 | best_val = this_val; |
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| 187 | cnt = 0; |
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| 188 | } |
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| 189 | else if (this_val==best_val) { |
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| 190 | cnt++; |
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| 191 | } |
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| 192 | else { |
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| 193 | cnt = 0; |
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| 194 | } |
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| 195 | } |
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| 196 | } |
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| 197 | |
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| 198 | rootEdge()->dumpNNI=2; |
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| 199 | |
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| 200 | aw_status("Searching best position"); |
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| 201 | |
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| 202 | AP_tree **blist; |
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| 203 | AP_tree_nlen *bl,*blf; |
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| 204 | long bsum = 0; |
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| 205 | long counter = 0; |
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| 206 | |
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| 207 | tree->buildBranchList(blist,bsum,AP_TRUE,-1); // get all branches |
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| 208 | AP_sequence::global_combineCount = 0; |
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| 209 | |
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| 210 | AP_tree *bestposl = tree->leftson; |
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| 211 | AP_tree *bestposr = tree->rightson; |
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| 212 | leaf->insert(bestposl); |
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| 213 | AP_FLOAT best_parsimony,akt_parsimony; |
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| 214 | best_parsimony = akt_parsimony = (*ap_main->tree_root)->costs(); |
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| 215 | |
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| 216 | for (counter = 0; !isits->abort_flag && blist[counter]; counter += 2) |
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| 217 | { |
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| 218 | if (isits->singlestatus && (counter & 0xf) == 0) { |
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| 219 | isits->abort_flag = (AP_BOOL)aw_status(counter/(bsum*2.0)); |
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| 220 | } |
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| 221 | |
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| 222 | bl = (AP_tree_nlen *)blist[counter]; |
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| 223 | blf = (AP_tree_nlen *)blist[counter+1]; |
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| 224 | if (blf->father == bl ) |
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| 225 | { |
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| 226 | bl = (AP_tree_nlen *)blist[counter+1]; |
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| 227 | blf = (AP_tree_nlen *)blist[counter]; |
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| 228 | } |
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| 229 | |
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| 230 | // if (blf->father) { //->father |
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| 231 | // blf->set_root(); |
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| 232 | // } |
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| 233 | |
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| 234 | if (bl->father) //->father |
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| 235 | { |
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| 236 | bl->set_root(); |
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| 237 | } |
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| 238 | |
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| 239 | leaf->moveTo(bl,0.5); |
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| 240 | akt_parsimony = (*ap_main->tree_root)->costs(); |
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| 241 | |
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| 242 | if (akt_parsimony<best_parsimony) |
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| 243 | { |
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| 244 | best_parsimony = akt_parsimony; |
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| 245 | bestposl = bl; |
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| 246 | bestposr = blf; |
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| 247 | } |
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| 248 | } |
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| 249 | delete blist; |
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| 250 | blist = 0; |
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| 251 | if (bestposl->father != bestposr) bestposl = bestposr; |
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| 252 | leaf->moveTo(bestposl,0.5); |
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| 253 | |
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| 254 | // calculate difference in father-sequence |
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| 255 | |
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| 256 | int baseDiff = 0; |
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| 257 | |
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| 258 | { |
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| 259 | AP_tree_nlen *fath = ((AP_tree_nlen*)bestposl)->Father()->Father(); |
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| 260 | char *seq_with_leaf; |
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| 261 | char *seq_without_leaf; |
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| 262 | long len_with_leaf; |
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| 263 | long len_without_leaf; |
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| 264 | long i; |
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| 265 | |
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| 266 | seq_with_leaf = fath->getSequence(); |
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| 267 | len_with_leaf = fath->sequence->sequence_len; |
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| 268 | |
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| 269 | |
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| 270 | ap_main->push(); |
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| 271 | leaf->remove(); |
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| 272 | |
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| 273 | seq_without_leaf = fath->getSequence(); |
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| 274 | len_without_leaf = fath->sequence->sequence_len; |
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| 275 | |
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| 276 | |
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| 277 | ap_main->pop(); |
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| 278 | |
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| 279 | |
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| 280 | if (len_with_leaf==len_without_leaf) { |
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| 281 | for (i=0; i<len_with_leaf; i++) { |
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| 282 | if (seq_with_leaf[i]!=seq_without_leaf[i]) { |
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| 283 | baseDiff++; |
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| 284 | } |
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| 285 | } |
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| 286 | } |
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| 287 | else { |
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| 288 | cout << "Laenge der Sequenz hat sich geaendert!!!"; |
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| 289 | } |
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| 290 | |
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| 291 | delete [] seq_with_leaf; |
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| 292 | delete [] seq_without_leaf; |
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| 293 | } |
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| 294 | |
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| 295 | rootEdge()->countSpecies(); |
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| 296 | |
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| 297 | // printf("Combines: %i\n",global_combineCount); |
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| 298 | |
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| 299 | if (!isits->quick_add_flag ) { |
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| 300 | int deep = -1; |
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| 301 | AP_tree_nlen *bestpos = (AP_tree_nlen*)bestposl; |
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| 302 | AP_tree_edge *e = bestpos->edgeTo(bestpos->Father()); |
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| 303 | |
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| 304 | if ((isits->currentspecies & 0xf ) == 0) deep = -1; |
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| 305 | |
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| 306 | aw_status("optimization"); |
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| 307 | e->dumpNNI = 1; |
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| 308 | e->distInsertBorder = e->distanceToBorder(INT_MAX,(AP_tree_nlen*)leaf); |
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| 309 | e->basesChanged = baseDiff; |
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| 310 | e->nni_rek(AP_FALSE, isits->abort_flag, deep); |
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| 311 | e->dumpNNI = 0; |
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| 312 | } |
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| 313 | |
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| 314 | return val; |
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| 315 | } |
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| 316 | |
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| 317 | static int sort_sequences_by_length(const char*, long leaf0_ptr, const char*, long leaf1_ptr) { |
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| 318 | AP_tree *leaf0 = (AP_tree*)leaf0_ptr; |
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| 319 | AP_tree *leaf1 = (AP_tree*)leaf1_ptr; |
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| 320 | |
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| 321 | AP_FLOAT len0 = leaf0->sequence->real_len(); |
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| 322 | AP_FLOAT len1 = leaf1->sequence->real_len(); |
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| 323 | |
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| 324 | return len0<len1 ? 1 : (len0>len1 ? -1 : 0); // longest sequence first |
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| 325 | } |
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| 326 | |
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| 327 | static long transform_gbd_to_leaf(const char *key,long val, void *) { |
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| 328 | if (!val) return val; |
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| 329 | |
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| 330 | AP_tree *tree = (*ap_main->tree_root); |
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| 331 | GBDATA *gb_node = (GBDATA *)val; |
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| 332 | GBDATA *gb_data = GBT_read_sequence(gb_node,ap_main->use); |
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| 333 | |
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| 334 | if (!gb_data) { |
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| 335 | sprintf(AW_ERROR_BUFFER,"Warning Species '%s' has no sequence '%s'", |
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| 336 | key,ap_main->use); |
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| 337 | aw_message(); |
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| 338 | return 0; |
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| 339 | } |
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| 340 | AP_tree *leaf = tree->dup(); |
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| 341 | leaf->gb_node = gb_node; |
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| 342 | leaf->name = strdup(key); |
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| 343 | leaf->is_leaf = GB_TRUE; |
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| 344 | leaf->sequence = leaf->tree_root->sequence_template->dup(); |
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| 345 | leaf->sequence->set(GB_read_char_pntr(gb_data)); |
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| 346 | return (long)leaf; |
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| 347 | } |
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| 348 | |
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| 349 | static AP_tree *insert_species_in_tree(const char *key, AP_tree *leaf, void *cd_isits) |
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| 350 | { |
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| 351 | if (!leaf) return leaf; |
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| 352 | |
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| 353 | InsertData *isits = (InsertData*)cd_isits; |
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| 354 | if (isits->abort_flag) return leaf; |
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| 355 | |
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| 356 | AP_tree *tree = (*ap_main->tree_root); |
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| 357 | |
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| 358 | |
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| 359 | if (leaf->sequence->real_len() < MIN_SEQUENCE_LENGTH) { |
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| 360 | sprintf(AW_ERROR_BUFFER,"Species %s has too short sequence (%i, minimum is %i)", |
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| 361 | key, (int)leaf->sequence->real_len(), MIN_SEQUENCE_LENGTH); |
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| 362 | aw_message(); |
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| 363 | delete leaf; |
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| 364 | return 0; |
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| 365 | } |
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| 366 | |
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| 367 | ++isits->currentspecies; |
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| 368 | if (isits->singlestatus) { |
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| 369 | sprintf(AW_ERROR_BUFFER, "Inserting Species %s (%li:%li)", |
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| 370 | key, isits->currentspecies, isits->maxspecies); |
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| 371 | aw_openstatus(AW_ERROR_BUFFER); |
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| 372 | } |
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| 373 | aw_status("Searching best position"); |
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| 374 | |
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| 375 | AP_tree **blist; |
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| 376 | AP_tree_nlen *bl,*blf; |
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| 377 | long bsum = 0; |
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| 378 | long counter = 0; |
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| 379 | |
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| 380 | tree->buildBranchList(blist,bsum,AP_TRUE,-1); // get all branches |
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| 381 | AP_sequence::global_combineCount = 0; |
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| 382 | |
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| 383 | AP_tree *bestposl = tree->leftson; |
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| 384 | AP_tree *bestposr = tree->rightson; |
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| 385 | leaf->insert(bestposl); |
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| 386 | AP_FLOAT best_parsimony,akt_parsimony; |
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| 387 | best_parsimony = akt_parsimony = (*ap_main->tree_root)->costs(); |
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| 388 | |
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| 389 | for (counter = 0;!isits->abort_flag && blist[counter];counter += 2) { |
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| 390 | if (isits->singlestatus && (counter & 0xf) == 0) { |
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| 391 | isits->abort_flag = (AP_BOOL)aw_status(counter/(bsum*2.0)); |
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| 392 | } |
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| 393 | bl = (AP_tree_nlen *)blist[counter]; |
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| 394 | blf = (AP_tree_nlen *)blist[counter+1]; |
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| 395 | if (blf->father == bl ) { |
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| 396 | bl = (AP_tree_nlen *)blist[counter+1]; |
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| 397 | blf = (AP_tree_nlen *)blist[counter]; |
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| 398 | } |
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| 399 | |
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| 400 | if (bl->father) { //->father |
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| 401 | bl->set_root(); |
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| 402 | } |
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| 403 | |
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| 404 | leaf->moveTo(bl,0.5); |
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| 405 | akt_parsimony = (*ap_main->tree_root)->costs(); |
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| 406 | if (akt_parsimony < best_parsimony) { |
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| 407 | best_parsimony = akt_parsimony; |
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| 408 | bestposl = bl; |
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| 409 | bestposr = blf; |
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| 410 | } |
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| 411 | |
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| 412 | } |
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| 413 | delete blist;blist = 0; |
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| 414 | if (bestposl->father != bestposr){ |
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| 415 | bestposl = bestposr; |
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| 416 | } |
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| 417 | leaf->moveTo(bestposl,0.5); |
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| 418 | |
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| 419 | if (!isits->quick_add_flag) { |
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| 420 | int deep = 5; |
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| 421 | if ( (isits->currentspecies & 0xf ) == 0) deep = -1; |
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| 422 | aw_status("optimization"); |
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| 423 | ((AP_tree_nlen *)bestposl->father)-> |
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| 424 | nn_interchange_rek(AP_FALSE, isits->abort_flag, deep, AP_BL_NNI_ONLY, GB_TRUE); |
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| 425 | } |
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| 426 | AP_tree *brother = leaf->brother(); |
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| 427 | if ( brother->is_leaf && // brother is a short sequence |
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| 428 | brother->sequence->real_len() *2 < leaf->sequence->real_len() && |
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| 429 | leaf->father->father){ // There are more than two species |
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| 430 | brother->remove(); |
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| 431 | leaf->remove(); |
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| 432 | isits->currentspecies--; |
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| 433 | char *label = GBS_global_string_copy("2:%s",leaf->name); |
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| 434 | insert_species_in_tree(label, leaf, cd_isits); // reinsert species |
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| 435 | delete label; |
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| 436 | isits->currentspecies--; |
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| 437 | label = GBS_global_string_copy("shortseq:%s",brother->name); |
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| 438 | insert_species_in_tree(label, brother, cd_isits); // reinsert short sequence |
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| 439 | delete label; |
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| 440 | } |
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| 441 | |
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| 442 | if (!isits->singlestatus) { |
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| 443 | isits->abort_flag |= aw_status(isits->currentspecies/(double)isits->maxspecies); |
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| 444 | } |
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| 445 | |
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| 446 | return leaf; |
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| 447 | } |
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| 448 | |
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| 449 | static long hash_insert_species_in_tree(const char *key, long leaf, void *cd_isits) { |
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| 450 | return (long)insert_species_in_tree(key, (AP_tree*)leaf, cd_isits); |
|---|
| 451 | } |
|---|
| 452 | |
|---|
| 453 | static long count_hash_elements(const char *,long val, void *cd_isits) { |
|---|
| 454 | if (val) { |
|---|
| 455 | InsertData *isits = (InsertData*)cd_isits; |
|---|
| 456 | isits->maxspecies++; |
|---|
| 457 | } |
|---|
| 458 | return val; |
|---|
| 459 | } |
|---|
| 460 | |
|---|
| 461 | static void nt_add(AW_window *, AWT_canvas *ntw, int what, AP_BOOL quick, int test) |
|---|
| 462 | { |
|---|
| 463 | GB_begin_transaction(GLOBAL_gb_main); |
|---|
| 464 | GB_HASH *hash = 0; |
|---|
| 465 | GB_ERROR error = 0; |
|---|
| 466 | AP_tree *oldrootleft = (*ap_main->tree_root)->leftson; |
|---|
| 467 | AP_tree *oldrootright = (*ap_main->tree_root)->rightson; |
|---|
| 468 | aw_openstatus("Search selected species"); |
|---|
| 469 | |
|---|
| 470 | if (what) |
|---|
| 471 | { |
|---|
| 472 | char *name = GBT_readOrCreate_string(GLOBAL_gb_main, AWAR_SPECIES_NAME, ""); |
|---|
| 473 | if (name && strlen(name)) { |
|---|
| 474 | GBDATA *gb_species = GBT_find_species(GLOBAL_gb_main,name); |
|---|
| 475 | if (gb_species) { |
|---|
| 476 | hash = GBS_create_hash(10, GB_MIND_CASE); |
|---|
| 477 | GBS_write_hash(hash,name,(long)gb_species); |
|---|
| 478 | } |
|---|
| 479 | else { |
|---|
| 480 | error = "Error: Selected Species not found"; |
|---|
| 481 | } |
|---|
| 482 | } |
|---|
| 483 | else { |
|---|
| 484 | error= "Please select an species" |
|---|
| 485 | " to select an species: 1. arb_edit: enable global cursor and select sequence" |
|---|
| 486 | " 2. arb_ntree: species/search and select species"; |
|---|
| 487 | } |
|---|
| 488 | free(name); |
|---|
| 489 | } |
|---|
| 490 | else { |
|---|
| 491 | hash = GBT_create_marked_species_hash(GLOBAL_gb_main); |
|---|
| 492 | } |
|---|
| 493 | GB_commit_transaction(GLOBAL_gb_main); |
|---|
| 494 | |
|---|
| 495 | if (!error) { |
|---|
| 496 | NT_remove_species_in_tree_from_hash(*ap_main->tree_root,hash); |
|---|
| 497 | |
|---|
| 498 | InsertData isits(quick); |
|---|
| 499 | |
|---|
| 500 | GBS_hash_do_loop(hash, count_hash_elements, &isits); |
|---|
| 501 | |
|---|
| 502 | aw_openstatus(GBS_global_string("Adding %li species", isits.maxspecies)); |
|---|
| 503 | |
|---|
| 504 | if (test) { |
|---|
| 505 | GBS_hash_do_loop(hash, insert_species_in_tree_test, &isits); |
|---|
| 506 | } |
|---|
| 507 | else { |
|---|
| 508 | aw_status("reading database"); |
|---|
| 509 | GB_begin_transaction(GLOBAL_gb_main); |
|---|
| 510 | GBS_hash_do_loop(hash, transform_gbd_to_leaf, NULL); |
|---|
| 511 | GB_commit_transaction(GLOBAL_gb_main); |
|---|
| 512 | GBS_hash_do_sorted_loop(hash, hash_insert_species_in_tree, sort_sequences_by_length, &isits); |
|---|
| 513 | } |
|---|
| 514 | if (!quick ) { |
|---|
| 515 | aw_status("final optimization"); |
|---|
| 516 | rootEdge()->nni_rek(AP_FALSE,isits.abort_flag,-1,GB_FALSE, AP_BL_NNI_ONLY); |
|---|
| 517 | } |
|---|
| 518 | |
|---|
| 519 | aw_status("Calculating Branch lengths"); |
|---|
| 520 | rootEdge()->nni_rek(AP_FALSE,isits.abort_flag,-1, GB_FALSE ,AP_BL_BL_ONLY); |
|---|
| 521 | |
|---|
| 522 | rootNode()->test_tree(); |
|---|
| 523 | rootNode()->compute_tree(GLOBAL_gb_main); |
|---|
| 524 | |
|---|
| 525 | if (oldrootleft->father == oldrootright) oldrootleft->set_root(); |
|---|
| 526 | else oldrootright->set_root(); |
|---|
| 527 | |
|---|
| 528 | aw_closestatus(); |
|---|
| 529 | } |
|---|
| 530 | |
|---|
| 531 | if (hash) GBS_free_hash(hash); |
|---|
| 532 | if (error) aw_message(error); |
|---|
| 533 | |
|---|
| 534 | AWT_TREE(ntw)->resort_tree(0); |
|---|
| 535 | ntw->zoom_reset(); |
|---|
| 536 | if (!error) pars_export_tree(); |
|---|
| 537 | } |
|---|
| 538 | |
|---|
| 539 | // ----------------------------------------- |
|---|
| 540 | // Adding partial sequences to tree |
|---|
| 541 | // ----------------------------------------- |
|---|
| 542 | |
|---|
| 543 | class PartialSequence { |
|---|
| 544 | GBDATA *gb_species; |
|---|
| 545 | mutable AP_tree *self; // self converted to leaf (ready for insertion) |
|---|
| 546 | const AP_tree *best_full_match; // full sequence position which matched best |
|---|
| 547 | long overlap; // size of overlapping region |
|---|
| 548 | long penalty; // weighted mismatches |
|---|
| 549 | bool released; |
|---|
| 550 | bool multi_match; |
|---|
| 551 | string multi_list; // list of equal-rated insertion-points (not containing self) |
|---|
| 552 | |
|---|
| 553 | AP_tree *get_self() const { |
|---|
| 554 | if (!self) { |
|---|
| 555 | ap_assert(!released); // request not possible, because leaf has already been released! |
|---|
| 556 | |
|---|
| 557 | self = (AP_tree*)transform_gbd_to_leaf(GBT_read_name(gb_species), (long)gb_species, NULL); |
|---|
| 558 | ap_assert(self); |
|---|
| 559 | } |
|---|
| 560 | return self; |
|---|
| 561 | } |
|---|
| 562 | |
|---|
| 563 | public: |
|---|
| 564 | PartialSequence(GBDATA *gb_species_) |
|---|
| 565 | : gb_species(gb_species_), self(0), best_full_match(0) |
|---|
| 566 | , overlap(0) , penalty(LONG_MAX), released(false), multi_match(false) |
|---|
| 567 | { |
|---|
| 568 | } |
|---|
| 569 | |
|---|
| 570 | ~PartialSequence() { ap_assert(self == 0); } |
|---|
| 571 | |
|---|
| 572 | GBDATA *get_species() const { return gb_species; } |
|---|
| 573 | const AP_tree *get_best_match() const { return best_full_match; } |
|---|
| 574 | AP_FLOAT get_branchlength() const { return AP_FLOAT(penalty)/overlap; } |
|---|
| 575 | void test_match(const AP_tree *leaf_full); |
|---|
| 576 | bool is_multi_match() const { return multi_match; } |
|---|
| 577 | |
|---|
| 578 | const char *get_name() const { |
|---|
| 579 | const char *name = get_self()->name; |
|---|
| 580 | ap_assert(name); |
|---|
| 581 | return name; |
|---|
| 582 | } |
|---|
| 583 | |
|---|
| 584 | string get_multilist() const { |
|---|
| 585 | ap_assert(is_multi_match()); |
|---|
| 586 | return string(best_full_match->name)+multi_list; |
|---|
| 587 | } |
|---|
| 588 | |
|---|
| 589 | AP_tree *release() { |
|---|
| 590 | AP_tree *s = self; |
|---|
| 591 | self = 0; |
|---|
| 592 | released = true; |
|---|
| 593 | return s; |
|---|
| 594 | } |
|---|
| 595 | |
|---|
| 596 | void dump() const { |
|---|
| 597 | printf("best match for '%s' is '%s' (overlap=%li penalty=%li)\n", |
|---|
| 598 | get_name(), best_full_match->name, |
|---|
| 599 | overlap, penalty); |
|---|
| 600 | } |
|---|
| 601 | |
|---|
| 602 | }; |
|---|
| 603 | |
|---|
| 604 | void PartialSequence::test_match(const AP_tree *leaf_full) { |
|---|
| 605 | long curr_overlap; |
|---|
| 606 | long curr_penalty; |
|---|
| 607 | |
|---|
| 608 | leaf_full->sequence->partial_match(get_self()->sequence, &curr_overlap, &curr_penalty); |
|---|
| 609 | |
|---|
| 610 | bool better = false; |
|---|
| 611 | |
|---|
| 612 | if (curr_overlap > overlap) { |
|---|
| 613 | better = true; |
|---|
| 614 | } |
|---|
| 615 | else if (curr_overlap == overlap) { |
|---|
| 616 | if (curr_penalty<penalty) { |
|---|
| 617 | better = true; |
|---|
| 618 | } |
|---|
| 619 | else if (curr_penalty == penalty) { |
|---|
| 620 | // found two equal-rated insertion points -> store data for warning |
|---|
| 621 | #if defined(DEBUG) |
|---|
| 622 | if (!multi_match) dump(); |
|---|
| 623 | printf("Another equal match is against '%s' (overlap=%li penalty=%li)\n", leaf_full->name, curr_overlap, curr_penalty); |
|---|
| 624 | #endif // DEBUG |
|---|
| 625 | // aw_message("Several full sequences match equal against one partial sequence"); |
|---|
| 626 | // aw_message("Please save a copy of the current database and inform Ralf!!!!"); |
|---|
| 627 | |
|---|
| 628 | multi_match = true; |
|---|
| 629 | multi_list.append(1, '/'); |
|---|
| 630 | multi_list.append(leaf_full->name); |
|---|
| 631 | } |
|---|
| 632 | } |
|---|
| 633 | |
|---|
| 634 | if (better) { |
|---|
| 635 | overlap = curr_overlap; |
|---|
| 636 | penalty = curr_penalty; |
|---|
| 637 | best_full_match = leaf_full; |
|---|
| 638 | multi_match = false; |
|---|
| 639 | multi_list = ""; |
|---|
| 640 | } |
|---|
| 641 | } |
|---|
| 642 | |
|---|
| 643 | static GB_ERROR nt_best_partial_match_rek(list<PartialSequence>& partial, AP_tree *tree) { |
|---|
| 644 | GB_ERROR error = 0; |
|---|
| 645 | |
|---|
| 646 | if (tree) { |
|---|
| 647 | if (tree->is_leaf && tree->name) { |
|---|
| 648 | if (tree->gb_node) { |
|---|
| 649 | int is_partial = GBT_is_partial(tree->gb_node, 0, true); // marks undef as 'full sequence' |
|---|
| 650 | if (is_partial == 0) { // do not consider other partial sequences |
|---|
| 651 | list<PartialSequence>::iterator i = partial.begin(); |
|---|
| 652 | list<PartialSequence>::iterator e = partial.end(); |
|---|
| 653 | for (; i != e; ++i) { |
|---|
| 654 | i->test_match(tree); |
|---|
| 655 | } |
|---|
| 656 | } |
|---|
| 657 | else if (is_partial == -1) { |
|---|
| 658 | error = GB_await_error(); |
|---|
| 659 | } |
|---|
| 660 | } |
|---|
| 661 | } |
|---|
| 662 | else { |
|---|
| 663 | error = nt_best_partial_match_rek(partial, tree->leftson); |
|---|
| 664 | if (!error) error = nt_best_partial_match_rek(partial, tree->rightson); |
|---|
| 665 | } |
|---|
| 666 | } |
|---|
| 667 | return error; |
|---|
| 668 | } |
|---|
| 669 | |
|---|
| 670 | static void count_partial_and_full(AP_tree *at, int *partial, int *full, int *zombies, int default_value, int define_if_undef) { |
|---|
| 671 | if (at->is_leaf) { |
|---|
| 672 | if (at->gb_node) { |
|---|
| 673 | int is_partial = GBT_is_partial(at->gb_node, default_value, define_if_undef); |
|---|
| 674 | if (is_partial) ++(*partial); |
|---|
| 675 | else ++(*full); |
|---|
| 676 | } |
|---|
| 677 | else { |
|---|
| 678 | ++(*zombies); |
|---|
| 679 | } |
|---|
| 680 | } |
|---|
| 681 | else { |
|---|
| 682 | count_partial_and_full(at->leftson, partial, full, zombies, default_value, define_if_undef); |
|---|
| 683 | count_partial_and_full(at->rightson, partial, full, zombies, default_value, define_if_undef); |
|---|
| 684 | } |
|---|
| 685 | } |
|---|
| 686 | |
|---|
| 687 | static AP_tree *find_least_deep_leaf(AP_tree *at, int depth, int *min_depth) { |
|---|
| 688 | if (depth >= *min_depth) { |
|---|
| 689 | return 0; // already found better or equal |
|---|
| 690 | } |
|---|
| 691 | |
|---|
| 692 | if (at->is_leaf) { |
|---|
| 693 | if (at->gb_node) { |
|---|
| 694 | *min_depth = depth; |
|---|
| 695 | return at; |
|---|
| 696 | } |
|---|
| 697 | return 0; |
|---|
| 698 | } |
|---|
| 699 | |
|---|
| 700 | AP_tree *left = find_least_deep_leaf(at->leftson, depth+1, min_depth); |
|---|
| 701 | AP_tree *right = find_least_deep_leaf(at->rightson, depth+1, min_depth); |
|---|
| 702 | |
|---|
| 703 | return right ? right : left; |
|---|
| 704 | } |
|---|
| 705 | |
|---|
| 706 | static long push_partial(const char *, long val, void *cd_partial) { |
|---|
| 707 | list<PartialSequence> *partial = reinterpret_cast<list<PartialSequence> *>(cd_partial); |
|---|
| 708 | partial->push_back(PartialSequence((GBDATA*)val)); |
|---|
| 709 | return val; |
|---|
| 710 | } |
|---|
| 711 | |
|---|
| 712 | static void nt_add_partial(AW_window */*aww*/, AWT_canvas *ntw) { |
|---|
| 713 | GB_begin_transaction(GLOBAL_gb_main); |
|---|
| 714 | GB_ERROR error = 0; |
|---|
| 715 | int full_marked_sequences = 0; |
|---|
| 716 | int partial_marked_sequences = 0; |
|---|
| 717 | int no_data = 0; // no data in alignment |
|---|
| 718 | |
|---|
| 719 | aw_openstatus("Adding partial sequences"); |
|---|
| 720 | |
|---|
| 721 | { |
|---|
| 722 | list<PartialSequence> partial; |
|---|
| 723 | { |
|---|
| 724 | GB_HASH *partial_hash = GBS_create_hash(GBT_get_species_hash_size(GLOBAL_gb_main), GB_MIND_CASE); |
|---|
| 725 | int marked_found = 0; |
|---|
| 726 | |
|---|
| 727 | for (GBDATA *gb_marked = GBT_first_marked_species(GLOBAL_gb_main); |
|---|
| 728 | !error && gb_marked; |
|---|
| 729 | gb_marked = GBT_next_marked_species(gb_marked)) |
|---|
| 730 | { |
|---|
| 731 | ++marked_found; |
|---|
| 732 | |
|---|
| 733 | if (GBT_read_sequence(gb_marked,ap_main->use)) { // species has sequence in alignment |
|---|
| 734 | const char *name = GBT_read_name(gb_marked); |
|---|
| 735 | |
|---|
| 736 | switch (GBT_is_partial(gb_marked, 1, true)) { // marks undef as 'partial sequence' |
|---|
| 737 | case 0: { // full sequences |
|---|
| 738 | aw_message(GBS_global_string("'%s' is a full sequence (cannot add partial)", name)); |
|---|
| 739 | ++full_marked_sequences; |
|---|
| 740 | break; |
|---|
| 741 | } |
|---|
| 742 | case 1: // partial sequences |
|---|
| 743 | ++partial_marked_sequences; |
|---|
| 744 | GBS_write_hash(partial_hash, name, (long)gb_marked); |
|---|
| 745 | break; |
|---|
| 746 | case -1: // error |
|---|
| 747 | error = GB_await_error(); |
|---|
| 748 | break; |
|---|
| 749 | default : |
|---|
| 750 | ap_assert(0); |
|---|
| 751 | break; |
|---|
| 752 | } |
|---|
| 753 | } |
|---|
| 754 | else { |
|---|
| 755 | no_data++; |
|---|
| 756 | } |
|---|
| 757 | } |
|---|
| 758 | |
|---|
| 759 | if (!error && !marked_found) error = "There are no marked species"; |
|---|
| 760 | |
|---|
| 761 | if (!error) { |
|---|
| 762 | NT_remove_species_in_tree_from_hash(*ap_main->tree_root,partial_hash); // skip all species which are in tree |
|---|
| 763 | GBS_hash_do_loop(partial_hash, push_partial, &partial); // build partial list from hash |
|---|
| 764 | |
|---|
| 765 | int partials_already_in_tree = partial_marked_sequences - partial.size(); |
|---|
| 766 | |
|---|
| 767 | if (no_data>0) aw_message(GBS_global_string("%i marked species have no data in '%s'", no_data, ap_main->use)); |
|---|
| 768 | if (full_marked_sequences>0) aw_message(GBS_global_string("%i marked species are declared full sequences", full_marked_sequences)); |
|---|
| 769 | if (partials_already_in_tree>0) aw_message(GBS_global_string("%i marked species are already in tree", partials_already_in_tree)); |
|---|
| 770 | |
|---|
| 771 | if (partial.empty()) error = "No species left to add"; |
|---|
| 772 | } |
|---|
| 773 | } |
|---|
| 774 | |
|---|
| 775 | if (!error) { |
|---|
| 776 | // find best matching full sequence for each partial sequence |
|---|
| 777 | error = nt_best_partial_match_rek(partial, *ap_main->tree_root); |
|---|
| 778 | |
|---|
| 779 | list<PartialSequence>::iterator i = partial.begin(); |
|---|
| 780 | list<PartialSequence>::iterator e = partial.end(); |
|---|
| 781 | |
|---|
| 782 | #if defined(DEBUG) |
|---|
| 783 | // show results : |
|---|
| 784 | for (; i != e; ++i) i->dump(); |
|---|
| 785 | i = partial.begin(); |
|---|
| 786 | #endif // DEBUG |
|---|
| 787 | |
|---|
| 788 | for (; i != e && !error; ++i) { |
|---|
| 789 | const char *name = i->get_name(); |
|---|
| 790 | |
|---|
| 791 | if (i->is_multi_match()) { |
|---|
| 792 | aw_message(GBS_global_string("Insertion of '%s' is ambiguous.\n" |
|---|
| 793 | "(took first of equal scored insertion points: %s)", |
|---|
| 794 | name, i->get_multilist().c_str())); |
|---|
| 795 | } |
|---|
| 796 | |
|---|
| 797 | AP_tree *part_leaf = i->release(); |
|---|
| 798 | AP_tree *full_seq = const_cast<AP_tree*>(i->get_best_match()); |
|---|
| 799 | AP_tree *brother = full_seq->brother(); |
|---|
| 800 | int is_partial = 0; |
|---|
| 801 | AP_tree *target = 0; |
|---|
| 802 | |
|---|
| 803 | if (brother->is_leaf) { |
|---|
| 804 | if (brother->gb_node) { |
|---|
| 805 | is_partial = GBT_is_partial(brother->gb_node, 0, 1); |
|---|
| 806 | |
|---|
| 807 | if (is_partial) { // brother is partial sequence |
|---|
| 808 | target = brother; // insert as brother of brother |
|---|
| 809 | } |
|---|
| 810 | else { |
|---|
| 811 | target = full_seq; // insert as brother of full_seq |
|---|
| 812 | } |
|---|
| 813 | } |
|---|
| 814 | else { |
|---|
| 815 | error = "There are zombies in your tree - please remove them"; |
|---|
| 816 | } |
|---|
| 817 | } |
|---|
| 818 | else { |
|---|
| 819 | int partial_count = 0; |
|---|
| 820 | int full_count = 0; |
|---|
| 821 | int zombie_count = 0; |
|---|
| 822 | |
|---|
| 823 | count_partial_and_full(brother, &partial_count, &full_count, &zombie_count, 0, 1); |
|---|
| 824 | |
|---|
| 825 | if (zombie_count) { |
|---|
| 826 | error = "There are zombies in your tree - please remove them"; |
|---|
| 827 | } |
|---|
| 828 | else if (full_count) { |
|---|
| 829 | // brother is a subtree containing full sequences |
|---|
| 830 | // -> add new brother to full_seq found above |
|---|
| 831 | target = full_seq; |
|---|
| 832 | } |
|---|
| 833 | else { // brother subtree only contains partial sequences |
|---|
| 834 | // find one of the least-deep leafs |
|---|
| 835 | int depth = INT_MAX; |
|---|
| 836 | target = find_least_deep_leaf(brother, 0, &depth); |
|---|
| 837 | is_partial = 1; |
|---|
| 838 | } |
|---|
| 839 | } |
|---|
| 840 | |
|---|
| 841 | |
|---|
| 842 | if (!error) { |
|---|
| 843 | #if defined(DEBUG) |
|---|
| 844 | printf("inserting '%s'\n", name); |
|---|
| 845 | #endif // DEBUG |
|---|
| 846 | part_leaf->insert(target); |
|---|
| 847 | |
|---|
| 848 | // we need to create the sequence of the father node! |
|---|
| 849 | AP_tree *father = part_leaf->father; |
|---|
| 850 | father->costs(); |
|---|
| 851 | |
|---|
| 852 | // ensure full-sequence is always on top |
|---|
| 853 | if (father->rightson == target) { |
|---|
| 854 | father->swap_sons(); |
|---|
| 855 | } |
|---|
| 856 | |
|---|
| 857 | if (!error) { |
|---|
| 858 | // now correct the branch lengths. |
|---|
| 859 | // First calc the original branchlen |
|---|
| 860 | GBT_LEN orglen = father->get_branchlength()+target->get_branchlength(); |
|---|
| 861 | |
|---|
| 862 | if (is_partial) { // we now have a subtree of partial sequences |
|---|
| 863 | brother->set_branchlength(orglen); // each partial sequence has it's branchlength. |
|---|
| 864 | father->set_branchlength(0); // all father branches are zero length |
|---|
| 865 | } |
|---|
| 866 | else { // we have a subtree of one full+one partial sequence |
|---|
| 867 | father->set_branchlength(orglen); // father branch represents original length (w/o partial seq) |
|---|
| 868 | full_seq->set_branchlength(0); // full seq has no sub-branch length |
|---|
| 869 | } |
|---|
| 870 | part_leaf->set_branchlength(i->get_branchlength()); |
|---|
| 871 | printf("Adding with branchlength=%f\n", i->get_branchlength()); |
|---|
| 872 | } |
|---|
| 873 | } |
|---|
| 874 | else { |
|---|
| 875 | delete part_leaf; |
|---|
| 876 | } |
|---|
| 877 | } |
|---|
| 878 | } |
|---|
| 879 | } |
|---|
| 880 | |
|---|
| 881 | aw_closestatus(); |
|---|
| 882 | |
|---|
| 883 | if (full_marked_sequences) { |
|---|
| 884 | aw_message(GBS_global_string("%i marked full sequences were not added", full_marked_sequences)); |
|---|
| 885 | } |
|---|
| 886 | |
|---|
| 887 | if (error) { |
|---|
| 888 | aw_message(error); |
|---|
| 889 | GB_abort_transaction(GLOBAL_gb_main); |
|---|
| 890 | } |
|---|
| 891 | else { |
|---|
| 892 | GB_commit_transaction(GLOBAL_gb_main); |
|---|
| 893 | } |
|---|
| 894 | |
|---|
| 895 | // AWT_TREE(ntw)->resort_tree(0); |
|---|
| 896 | ntw->zoom_reset(); |
|---|
| 897 | if (!error) pars_export_tree(); |
|---|
| 898 | } |
|---|
| 899 | |
|---|
| 900 | // ----------------------------- |
|---|
| 901 | // add marked / selected |
|---|
| 902 | // ----------------------------- |
|---|
| 903 | |
|---|
| 904 | // normal versions : |
|---|
| 905 | |
|---|
| 906 | static void NT_add(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 907 | // what == 0 marked ==1 selected |
|---|
| 908 | nt_add(aww,ntw,what,AP_FALSE,0); |
|---|
| 909 | } |
|---|
| 910 | |
|---|
| 911 | static void NT_quick_add(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 912 | // what == 0 marked ==1 selected |
|---|
| 913 | nt_add(aww,ntw,what,AP_TRUE,0); |
|---|
| 914 | } |
|---|
| 915 | |
|---|
| 916 | // test versions : |
|---|
| 917 | |
|---|
| 918 | #if defined(TEST_FUNCTIONS) |
|---|
| 919 | static void NT_add_test(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 920 | // what == 0 marked ==1 selected |
|---|
| 921 | nt_add(aww,ntw,what,AP_FALSE,1); |
|---|
| 922 | } |
|---|
| 923 | |
|---|
| 924 | static void NT_quick_add_test(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 925 | // what == 0 marked ==1 selected |
|---|
| 926 | nt_add(aww,ntw,what,AP_TRUE,1); |
|---|
| 927 | } |
|---|
| 928 | #endif // TEST_FUNCTIONS |
|---|
| 929 | |
|---|
| 930 | // ----------------------------------------- |
|---|
| 931 | // remove and add marked / selected |
|---|
| 932 | // ----------------------------------------- |
|---|
| 933 | |
|---|
| 934 | static void NT_radd_internal(AW_window * aww, AWT_canvas *ntw, int what, AP_BOOL quick, int test) { |
|---|
| 935 | // what == 0 marked ==1 selected |
|---|
| 936 | |
|---|
| 937 | AW_awar *awar_best_pars = aww->get_root()->awar(AWAR_BEST_PARSIMONY); |
|---|
| 938 | int oldparsval = awar_best_pars->read_int(); |
|---|
| 939 | |
|---|
| 940 | NT_remove_leafs(0,ntw,AWT_REMOVE_BUT_DONT_FREE | AWT_REMOVE_MARKED); |
|---|
| 941 | |
|---|
| 942 | // restore old parsimony value (otherwise the state where species were removed would count) : |
|---|
| 943 | awar_best_pars->write_int(oldparsval); |
|---|
| 944 | |
|---|
| 945 | nt_add(aww,ntw,what,quick,test); |
|---|
| 946 | } |
|---|
| 947 | |
|---|
| 948 | // normal versions : |
|---|
| 949 | |
|---|
| 950 | static void NT_radd(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 951 | // what == 0 marked ==1 selected |
|---|
| 952 | NT_radd_internal(aww, ntw, what, AP_FALSE, 0); |
|---|
| 953 | } |
|---|
| 954 | |
|---|
| 955 | static void NT_rquick_add(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 956 | // what == 0 marked ==1 selected |
|---|
| 957 | NT_radd_internal(aww, ntw, what, AP_TRUE, 0); |
|---|
| 958 | } |
|---|
| 959 | |
|---|
| 960 | // static void NT_radd_test_internal(AW_window * aww, AWT_canvas *ntw, int what, AP_BOOL quick) { |
|---|
| 961 | // // what == 0 marked ==1 selected |
|---|
| 962 | // NT_remove_leafs(0,ntw,AWT_REMOVE_BUT_DONT_FREE | AWT_REMOVE_MARKED); |
|---|
| 963 | // nt_add(aww,ntw,what,quick,1); |
|---|
| 964 | // } |
|---|
| 965 | |
|---|
| 966 | // test versions : |
|---|
| 967 | |
|---|
| 968 | #if defined(TEST_FUNCTIONS) |
|---|
| 969 | static void NT_radd_test(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 970 | // what == 0 marked ==1 selected |
|---|
| 971 | NT_radd_internal(aww, ntw, what, AP_FALSE, 1); |
|---|
| 972 | } |
|---|
| 973 | |
|---|
| 974 | static void NT_rquick_add_test(AW_window * aww, AWT_canvas *ntw, int what) { |
|---|
| 975 | // what == 0 marked ==1 selected |
|---|
| 976 | NT_radd_internal(aww, ntw, what, AP_TRUE, 1); |
|---|
| 977 | } |
|---|
| 978 | #endif // TEST_FUNCTIONS |
|---|
| 979 | |
|---|
| 980 | // -------------------------------------------------------------------------------- |
|---|
| 981 | // Add Partial sequences |
|---|
| 982 | // -------------------------------------------------------------------------------- |
|---|
| 983 | |
|---|
| 984 | |
|---|
| 985 | static void NT_partial_add(AW_window *aww, AW_CL cl_ntw, AW_CL) { |
|---|
| 986 | AWT_canvas *ntw = (AWT_canvas*)cl_ntw; |
|---|
| 987 | nt_add_partial(aww, ntw); |
|---|
| 988 | } |
|---|
| 989 | |
|---|
| 990 | // -------------------------------------------------------------------------------- |
|---|
| 991 | |
|---|
| 992 | static void NT_branch_lengths(AW_window *, AWT_canvas *ntw) { |
|---|
| 993 | aw_openstatus("Calculating Branch Lengths"); |
|---|
| 994 | int abort_flag = AP_FALSE; |
|---|
| 995 | rootEdge()->nni_rek(AP_FALSE, abort_flag, -1, GB_FALSE, AP_BL_BL_ONLY); |
|---|
| 996 | |
|---|
| 997 | aw_closestatus(); |
|---|
| 998 | AWT_TREE(ntw)->resort_tree(0); |
|---|
| 999 | |
|---|
| 1000 | ntw->zoom_reset(); |
|---|
| 1001 | ntw->refresh(); |
|---|
| 1002 | pars_export_tree(); |
|---|
| 1003 | } |
|---|
| 1004 | |
|---|
| 1005 | static void NT_bootstrap(AW_window *aw,AWT_canvas *ntw,AW_CL limit_only) |
|---|
| 1006 | { |
|---|
| 1007 | AW_POPUP_HELP(aw, (AW_CL)"pa_bootstrap.hlp"); |
|---|
| 1008 | aw_openstatus("Calculating Bootstrap Limit"); |
|---|
| 1009 | int abort_flag = AP_FALSE; |
|---|
| 1010 | rootEdge()->nni_rek(AP_FALSE, abort_flag, -1, GB_FALSE, |
|---|
| 1011 | limit_only ? AP_BL_BOOTSTRAP_LIMIT : AP_BL_BOOTSTRAP_ESTIMATE); |
|---|
| 1012 | aw_closestatus(); |
|---|
| 1013 | |
|---|
| 1014 | AWT_TREE(ntw)->resort_tree(0); |
|---|
| 1015 | |
|---|
| 1016 | AWT_TREE(ntw)->tree_root_display = AWT_TREE(ntw)->tree_root; |
|---|
| 1017 | ntw->zoom_reset(); |
|---|
| 1018 | ntw->refresh(); |
|---|
| 1019 | pars_export_tree(); |
|---|
| 1020 | } |
|---|
| 1021 | |
|---|
| 1022 | static void NT_optimize(AW_window *, AWT_canvas *ntw) |
|---|
| 1023 | { |
|---|
| 1024 | aw_openstatus("Optimize Tree"); |
|---|
| 1025 | |
|---|
| 1026 | PARS_optimizer_cb((*ap_main->tree_root)); |
|---|
| 1027 | rootNode()->test_tree(); |
|---|
| 1028 | |
|---|
| 1029 | aw_openstatus("Calculating Branch Lengths"); |
|---|
| 1030 | int abort_flag = AP_FALSE; |
|---|
| 1031 | rootEdge()->nni_rek(AP_FALSE, abort_flag, -1, GB_FALSE, AP_BL_BL_ONLY); |
|---|
| 1032 | AWT_TREE(ntw)->resort_tree(0); |
|---|
| 1033 | rootNode()->compute_tree(GLOBAL_gb_main); |
|---|
| 1034 | aw_closestatus(); |
|---|
| 1035 | ntw->zoom_reset(); |
|---|
| 1036 | ntw->refresh(); |
|---|
| 1037 | pars_export_tree(); |
|---|
| 1038 | } |
|---|
| 1039 | |
|---|
| 1040 | static void NT_recursiveNNI(AW_window *,AWT_canvas *ntw) |
|---|
| 1041 | { |
|---|
| 1042 | aw_openstatus("Recursive NNI"); |
|---|
| 1043 | int abort_flag = AP_FALSE; |
|---|
| 1044 | |
|---|
| 1045 | AP_FLOAT thisPars = rootNode()->costs(); |
|---|
| 1046 | AP_FLOAT lastPars = -1.0; |
|---|
| 1047 | |
|---|
| 1048 | aw_status(GBS_global_string("Old parsimony: %f", thisPars)); |
|---|
| 1049 | while (thisPars!=lastPars && abort_flag == AP_FALSE) { |
|---|
| 1050 | lastPars = thisPars; |
|---|
| 1051 | thisPars = rootEdge()->nni_rek(AP_FALSE, abort_flag, -1, GB_TRUE); |
|---|
| 1052 | abort_flag |= aw_status(GBS_global_string("New Parsimony: %f",thisPars)); |
|---|
| 1053 | } |
|---|
| 1054 | |
|---|
| 1055 | aw_status("Calculating Branch Lengths"); |
|---|
| 1056 | abort_flag = AP_FALSE; |
|---|
| 1057 | rootEdge()->nni_rek(AP_FALSE, abort_flag, -1, GB_FALSE, AP_BL_BL_ONLY); |
|---|
| 1058 | |
|---|
| 1059 | AWT_TREE(ntw)->resort_tree(0); |
|---|
| 1060 | rootNode()->compute_tree(GLOBAL_gb_main); |
|---|
| 1061 | aw_closestatus(); |
|---|
| 1062 | ntw->zoom_reset(); |
|---|
| 1063 | ntw->refresh(); |
|---|
| 1064 | pars_export_tree(); |
|---|
| 1065 | } |
|---|
| 1066 | |
|---|
| 1067 | static AW_window *NT_create_tree_setting(AW_root *aw_root) |
|---|
| 1068 | { |
|---|
| 1069 | static AW_window_simple *aws = 0; |
|---|
| 1070 | if (aws) return (AW_window *)aws; |
|---|
| 1071 | |
|---|
| 1072 | aws = new AW_window_simple; |
|---|
| 1073 | aws->init( aw_root, "SAVE_DB","SAVE ARB DB"); |
|---|
| 1074 | aws->load_xfig("awt/tree_settings.fig"); |
|---|
| 1075 | |
|---|
| 1076 | aws->at("close");aws->callback((AW_CB0)AW_POPDOWN); |
|---|
| 1077 | aws->create_button("CLOSE","CLOSE","C"); |
|---|
| 1078 | |
|---|
| 1079 | aws->at("help");aws->callback(AW_POPUP_HELP,(AW_CL)"nt_tree_settings.hlp"); |
|---|
| 1080 | aws->create_button("HELP","HELP","H"); |
|---|
| 1081 | |
|---|
| 1082 | aws->at("button"); |
|---|
| 1083 | aws->auto_space(10,10); |
|---|
| 1084 | aws->label_length(30); |
|---|
| 1085 | |
|---|
| 1086 | aws->label("Base Line Width"); |
|---|
| 1087 | aws->create_input_field(AWAR_DTREE_BASELINEWIDTH,4); |
|---|
| 1088 | aws->at_newline(); |
|---|
| 1089 | |
|---|
| 1090 | aws->label("Relative vert. Dist"); |
|---|
| 1091 | aws->create_input_field(AWAR_DTREE_VERICAL_DIST,4); |
|---|
| 1092 | aws->at_newline(); |
|---|
| 1093 | |
|---|
| 1094 | aws->label("Auto Jump (list tree)"); |
|---|
| 1095 | aws->create_toggle(AWAR_DTREE_AUTO_JUMP); |
|---|
| 1096 | aws->at_newline(); |
|---|
| 1097 | |
|---|
| 1098 | |
|---|
| 1099 | return (AW_window *)aws; |
|---|
| 1100 | |
|---|
| 1101 | } |
|---|
| 1102 | |
|---|
| 1103 | static void PA_focus_cb(AW_window *,GBDATA *gb_main_par) |
|---|
| 1104 | { |
|---|
| 1105 | GB_transaction dummy(gb_main_par); |
|---|
| 1106 | } |
|---|
| 1107 | |
|---|
| 1108 | /****************************************************** |
|---|
| 1109 | Test-Funktionen |
|---|
| 1110 | ******************************************************/ |
|---|
| 1111 | |
|---|
| 1112 | #if defined(TEST_FUNCTIONS) |
|---|
| 1113 | static void refreshTree(AWT_canvas *ntw) { |
|---|
| 1114 | GB_transaction gb_dummy(ntw->gb_main); |
|---|
| 1115 | |
|---|
| 1116 | AWT_TREE(ntw)->check_update(ntw->gb_main); |
|---|
| 1117 | GB_ERROR error = AWT_TREE(ntw)->save(ntw->gb_main,0,0,0); |
|---|
| 1118 | if (error) aw_message(error); |
|---|
| 1119 | ntw->zoom_reset(); |
|---|
| 1120 | ntw->refresh(); |
|---|
| 1121 | } |
|---|
| 1122 | |
|---|
| 1123 | static void testTree(AP_tree_nlen *tree,int *nodeCount, int *edgeCount) |
|---|
| 1124 | { |
|---|
| 1125 | tree->test(); |
|---|
| 1126 | (*nodeCount)++; |
|---|
| 1127 | |
|---|
| 1128 | if (tree->father) // we do only test edges if were not at root |
|---|
| 1129 | { |
|---|
| 1130 | AP_tree_edge *e =0; |
|---|
| 1131 | int skipTest=0; |
|---|
| 1132 | |
|---|
| 1133 | if (tree->father->father) |
|---|
| 1134 | { |
|---|
| 1135 | e = tree->edgeTo(tree->Father()); |
|---|
| 1136 | } |
|---|
| 1137 | else // son of root! |
|---|
| 1138 | { |
|---|
| 1139 | if (tree->father->leftson==(AP_tree*)tree) // to not test twice |
|---|
| 1140 | { |
|---|
| 1141 | e = tree->edgeTo(tree->Brother()); |
|---|
| 1142 | } |
|---|
| 1143 | else |
|---|
| 1144 | { |
|---|
| 1145 | skipTest=1; |
|---|
| 1146 | } |
|---|
| 1147 | } |
|---|
| 1148 | |
|---|
| 1149 | if (!skipTest) |
|---|
| 1150 | { |
|---|
| 1151 | if (e) |
|---|
| 1152 | { |
|---|
| 1153 | int dist2bord; |
|---|
| 1154 | |
|---|
| 1155 | e->test(); |
|---|
| 1156 | (*edgeCount)++; |
|---|
| 1157 | |
|---|
| 1158 | dist2bord = e->distanceToBorder(); |
|---|
| 1159 | if (dist2bord != e->Distance()) |
|---|
| 1160 | { |
|---|
| 1161 | cout << *e << "distance error: should=" << dist2bord << " is=" << e->Distance() << endl; |
|---|
| 1162 | } |
|---|
| 1163 | } |
|---|
| 1164 | else |
|---|
| 1165 | { |
|---|
| 1166 | cout << *tree << "has no edge to father\n"; |
|---|
| 1167 | } |
|---|
| 1168 | } |
|---|
| 1169 | } |
|---|
| 1170 | |
|---|
| 1171 | if (!tree->is_leaf) |
|---|
| 1172 | { |
|---|
| 1173 | testTree((AP_tree_nlen*)tree->leftson,nodeCount,edgeCount); |
|---|
| 1174 | testTree((AP_tree_nlen*)tree->rightson,nodeCount,edgeCount); |
|---|
| 1175 | } |
|---|
| 1176 | } |
|---|
| 1177 | |
|---|
| 1178 | static void TEST_testWholeTree(AW_window *, AWT_canvas *) |
|---|
| 1179 | // Tests the whole tree structure (edges and nodes) for consistency |
|---|
| 1180 | { |
|---|
| 1181 | AP_tree_nlen *root = (AP_tree_nlen*)*ap_main->tree_root; |
|---|
| 1182 | int nodes = 0; |
|---|
| 1183 | int edges = 0; |
|---|
| 1184 | |
|---|
| 1185 | if (root->father) |
|---|
| 1186 | { |
|---|
| 1187 | int m = INT_MAX; |
|---|
| 1188 | |
|---|
| 1189 | cout << "OOPS! Root has father:\n" << *root << '\n'; |
|---|
| 1190 | while (m-- && root->father) root = root->Father(); |
|---|
| 1191 | |
|---|
| 1192 | if (root->father) |
|---|
| 1193 | { |
|---|
| 1194 | cout << "Root node lost between:\n" |
|---|
| 1195 | << *root << '\n' |
|---|
| 1196 | << *(root->Father()) << '\n'; |
|---|
| 1197 | } |
|---|
| 1198 | else |
|---|
| 1199 | { |
|---|
| 1200 | cout << "Found a root:\n" << *root << "\n Let's test from here:\n"; |
|---|
| 1201 | } |
|---|
| 1202 | } |
|---|
| 1203 | |
|---|
| 1204 | root->test_tree(); |
|---|
| 1205 | testTree(root, &nodes, &edges); |
|---|
| 1206 | |
|---|
| 1207 | cout << "Nodes tested: " << nodes << '\n' |
|---|
| 1208 | << "Edges tested: " << edges << '\n'; |
|---|
| 1209 | } |
|---|
| 1210 | #endif // TEST_FUNCTIONS |
|---|
| 1211 | |
|---|
| 1212 | static int dumpNodes(AP_tree_nlen *node) |
|---|
| 1213 | { |
|---|
| 1214 | int cnt = 1; |
|---|
| 1215 | |
|---|
| 1216 | cout << *node |
|---|
| 1217 | << "(llen=" << node->leftlen |
|---|
| 1218 | << ",rlen=" << node->rightlen << ")\n"; |
|---|
| 1219 | |
|---|
| 1220 | if (!node->is_leaf) |
|---|
| 1221 | { |
|---|
| 1222 | cnt += dumpNodes(node->Leftson()); |
|---|
| 1223 | cnt += dumpNodes(node->Rightson()); |
|---|
| 1224 | } |
|---|
| 1225 | |
|---|
| 1226 | return cnt; |
|---|
| 1227 | } |
|---|
| 1228 | |
|---|
| 1229 | #if defined(TEST_FUNCTIONS) |
|---|
| 1230 | static void TEST_dumpNodes(AW_window *, AWT_canvas *) |
|---|
| 1231 | { |
|---|
| 1232 | AP_tree_nlen *root = (AP_tree_nlen*)*ap_main->tree_root; |
|---|
| 1233 | int cnt; |
|---|
| 1234 | |
|---|
| 1235 | cout << "----- Dumping all nodes in tree\n"; |
|---|
| 1236 | cnt = dumpNodes(root); |
|---|
| 1237 | cout << "----- " << cnt << "nodes dumped!\n"; |
|---|
| 1238 | } |
|---|
| 1239 | #endif // TEST_FUNCTIONS |
|---|
| 1240 | |
|---|
| 1241 | static void setBranchlens(AP_tree_nlen *node,double newLen) |
|---|
| 1242 | { |
|---|
| 1243 | node->setBranchlen(newLen,newLen); |
|---|
| 1244 | |
|---|
| 1245 | if (!node->is_leaf) |
|---|
| 1246 | { |
|---|
| 1247 | setBranchlens(node->Leftson(),newLen); |
|---|
| 1248 | setBranchlens(node->Rightson(),newLen); |
|---|
| 1249 | } |
|---|
| 1250 | } |
|---|
| 1251 | #if defined(TEST_FUNCTIONS) |
|---|
| 1252 | static void TEST_setBranchlen(AW_window *, AWT_canvas *ntw) |
|---|
| 1253 | { |
|---|
| 1254 | AP_tree_nlen *root = (AP_tree_nlen*)*ap_main->tree_root; |
|---|
| 1255 | |
|---|
| 1256 | setBranchlens(root,1.0); |
|---|
| 1257 | refreshTree(ntw); |
|---|
| 1258 | } |
|---|
| 1259 | #endif // TEST_FUNCTIONS |
|---|
| 1260 | |
|---|
| 1261 | /* |
|---|
| 1262 | static AP_tree_nlen *getRandomSonOf(AP_tree_nlen *daddy, int innerNodeAllowed,int rootAllowed) |
|---|
| 1263 | { |
|---|
| 1264 | if (daddy->is_leaf) return daddy; |
|---|
| 1265 | int r = rand() % (innerNodeAllowed && rootAllowed ? 3 : 2); |
|---|
| 1266 | if (r==2) return daddy; |
|---|
| 1267 | return getRandomSonOf(r ? daddy->Leftson() : daddy->Rightson(), |
|---|
| 1268 | innerNodeAllowed, 1); |
|---|
| 1269 | } |
|---|
| 1270 | static void TEST_performRandomMoves(AW_window *aww,AWT_canvas *ntw) |
|---|
| 1271 | { |
|---|
| 1272 | AWUSE(aww); |
|---|
| 1273 | |
|---|
| 1274 | int cnt=10000; |
|---|
| 1275 | |
|---|
| 1276 | while(cnt) |
|---|
| 1277 | { |
|---|
| 1278 | AP_tree_nlen *root = (AP_tree_nlen*)*ap_main->tree_root; |
|---|
| 1279 | AP_tree_nlen *source = getRandomSonOf(root,1,0); |
|---|
| 1280 | AP_tree_nlen *dest = getRandomSonOf(root,1,0); |
|---|
| 1281 | |
|---|
| 1282 | if (source!=dest && !dest->is_son(source)) |
|---|
| 1283 | { |
|---|
| 1284 | root->setBranchlen(1.0,1.0); |
|---|
| 1285 | source->setBranchlen(1.0,1.0); |
|---|
| 1286 | dest->setBranchlen(1.0,1.0); |
|---|
| 1287 | |
|---|
| 1288 | char *error = source->move(dest,0.5); |
|---|
| 1289 | |
|---|
| 1290 | if (error) |
|---|
| 1291 | { |
|---|
| 1292 | cout << error << '\n'; |
|---|
| 1293 | break; |
|---|
| 1294 | } |
|---|
| 1295 | |
|---|
| 1296 | cnt--; |
|---|
| 1297 | // cout << "Moves left: " << cnt << '\n'; |
|---|
| 1298 | } |
|---|
| 1299 | } |
|---|
| 1300 | |
|---|
| 1301 | cout << "Testing tree\n"; |
|---|
| 1302 | TEST_testWholeTree(aww,ntw); |
|---|
| 1303 | |
|---|
| 1304 | // cout << "setting branchlens\n"; |
|---|
| 1305 | // TEST_setBranchlen(aww,ntw); |
|---|
| 1306 | |
|---|
| 1307 | // cout << "dumping nodes\n"; |
|---|
| 1308 | // TEST_dumpNodes(aww,ntw); |
|---|
| 1309 | |
|---|
| 1310 | cout << "done\n"; |
|---|
| 1311 | // refreshTree(ntw); |
|---|
| 1312 | } |
|---|
| 1313 | */ |
|---|
| 1314 | |
|---|
| 1315 | #if defined(TEST_FUNCTIONS) |
|---|
| 1316 | static void TEST_mixTree(AW_window *, AWT_canvas *ntw) |
|---|
| 1317 | { |
|---|
| 1318 | rootEdge()->mixTree(100); |
|---|
| 1319 | refreshTree(ntw); |
|---|
| 1320 | } |
|---|
| 1321 | |
|---|
| 1322 | static void TEST_sortTreeByName(AW_window *, AWT_canvas *ntw) |
|---|
| 1323 | { |
|---|
| 1324 | AP_tree_nlen *root = (AP_tree_nlen*)*ap_main->tree_root; |
|---|
| 1325 | |
|---|
| 1326 | root->sortByName(); |
|---|
| 1327 | refreshTree(ntw); |
|---|
| 1328 | } |
|---|
| 1329 | |
|---|
| 1330 | static void TEST_buildAndDumpChain(AW_window *, AWT_canvas *) |
|---|
| 1331 | { |
|---|
| 1332 | AP_tree_nlen *root = (AP_tree_nlen*)*ap_main->tree_root; |
|---|
| 1333 | |
|---|
| 1334 | root->Leftson()->edgeTo(root->Rightson())->testChain(2); |
|---|
| 1335 | root->Leftson()->edgeTo(root->Rightson())->testChain(3); |
|---|
| 1336 | root->Leftson()->edgeTo(root->Rightson())->testChain(4); |
|---|
| 1337 | root->Leftson()->edgeTo(root->Rightson())->testChain(5); |
|---|
| 1338 | root->Leftson()->edgeTo(root->Rightson())->testChain(6); |
|---|
| 1339 | root->Leftson()->edgeTo(root->Rightson())->testChain(7); |
|---|
| 1340 | root->Leftson()->edgeTo(root->Rightson())->testChain(8); |
|---|
| 1341 | root->Leftson()->edgeTo(root->Rightson())->testChain(9); |
|---|
| 1342 | root->Leftson()->edgeTo(root->Rightson())->testChain(10); |
|---|
| 1343 | root->Leftson()->edgeTo(root->Rightson())->testChain(11); |
|---|
| 1344 | root->Leftson()->edgeTo(root->Rightson())->testChain(-1); |
|---|
| 1345 | } |
|---|
| 1346 | |
|---|
| 1347 | static void init_TEST_menu(AW_window_menu_modes *awm,AWT_canvas *ntw) |
|---|
| 1348 | { |
|---|
| 1349 | awm->create_menu("Test[debug]", "T", "", AWM_ALL ); |
|---|
| 1350 | |
|---|
| 1351 | awm->insert_menu_topic(0, "Test edges", "T", "", AWM_ALL, (AW_CB)TEST_testWholeTree, (AW_CL)ntw, 0); |
|---|
| 1352 | awm->insert_menu_topic(0, "Mix tree", "M", "", AWM_ALL, (AW_CB)TEST_mixTree, (AW_CL)ntw, 0); |
|---|
| 1353 | awm->insert_menu_topic(0, "Dump nodes", "D", "", AWM_ALL, (AW_CB)TEST_dumpNodes, (AW_CL)ntw, 0); |
|---|
| 1354 | awm->insert_menu_topic(0, "Set branchlens", "b", "", AWM_ALL, (AW_CB)TEST_setBranchlen, (AW_CL)ntw, 0); |
|---|
| 1355 | awm->insert_menu_topic(0, "Sort tree by name", "S", "", AWM_ALL, (AW_CB)TEST_sortTreeByName, (AW_CL)ntw, 0); |
|---|
| 1356 | awm->insert_menu_topic(0, "Build & dump chain", "c", "", AWM_ALL, (AW_CB)TEST_buildAndDumpChain, (AW_CL)ntw, 0); |
|---|
| 1357 | awm->insert_separator(); |
|---|
| 1358 | awm->insert_menu_topic(0, "Add marked species", "A", "pa_quick.hlp", AWM_ALL, (AW_CB)NT_quick_add_test, (AW_CL)ntw, 0); |
|---|
| 1359 | awm->insert_menu_topic(0, "Add marked species + NNI", "N", "pa_add.hlp", AWM_ALL, (AW_CB)NT_add_test, (AW_CL)ntw, 0); |
|---|
| 1360 | awm->insert_menu_topic(0, "Remove & add marked species", "o", "pa_add.hlp", AWM_ALL, (AW_CB)NT_rquick_add_test, (AW_CL)ntw, 0); |
|---|
| 1361 | awm->insert_menu_topic(0, "Remove & add marked + NNI", "v", "pa_add.hlp", AWM_ALL, (AW_CB)NT_radd_test, (AW_CL)ntw, 0); |
|---|
| 1362 | awm->insert_separator(); |
|---|
| 1363 | awm->insert_menu_topic(0, "Add selected species", "l", "pa_quick_sel.hlp", AWM_ALL, (AW_CB)NT_quick_add_test, (AW_CL)ntw, 1); |
|---|
| 1364 | awm->insert_menu_topic(0, "Add selected species + NNI", "I", "pa_add_sel.hlp", AWM_ALL, (AW_CB)NT_add_test, (AW_CL)ntw, 1); |
|---|
| 1365 | } |
|---|
| 1366 | #endif // TEST_FUNCTIONS |
|---|
| 1367 | |
|---|
| 1368 | static GB_ERROR pars_check_size(AW_root *awr){ |
|---|
| 1369 | char *tree_name = awr->awar(AWAR_TREE)->read_string(); |
|---|
| 1370 | char *filter = awr->awar(AWAR_FILTER_FILTER)->read_string(); |
|---|
| 1371 | GB_ERROR error = 0; |
|---|
| 1372 | long ali_len = 0; |
|---|
| 1373 | if (strlen(filter)){ |
|---|
| 1374 | int i; |
|---|
| 1375 | for (i=0;filter[i];i++){ |
|---|
| 1376 | if (filter[i] != '0') ali_len++; |
|---|
| 1377 | } |
|---|
| 1378 | }else{ |
|---|
| 1379 | char *ali_name = awr->awar(AWAR_ALIGNMENT)->read_string(); |
|---|
| 1380 | ali_len = GBT_get_alignment_len(GLOBAL_gb_main,ali_name); |
|---|
| 1381 | delete ali_name; |
|---|
| 1382 | } |
|---|
| 1383 | |
|---|
| 1384 | long tree_size = GBT_size_of_tree(GLOBAL_gb_main,tree_name); |
|---|
| 1385 | if (tree_size == -1) { |
|---|
| 1386 | error = GB_export_error("Please select an existing tree"); |
|---|
| 1387 | } |
|---|
| 1388 | else { |
|---|
| 1389 | if ((unsigned long)(ali_len * tree_size * 4/ 1000) > GB_get_physical_memory()){ |
|---|
| 1390 | error = GB_export_error("Very big tree"); |
|---|
| 1391 | } |
|---|
| 1392 | } |
|---|
| 1393 | free(filter); |
|---|
| 1394 | free(tree_name); |
|---|
| 1395 | return error; |
|---|
| 1396 | } |
|---|
| 1397 | |
|---|
| 1398 | static void pars_reset_optimal_parsimony(AW_window *aww, AW_CL *cl_ntw) { |
|---|
| 1399 | AW_root *awr = aww->get_root(); |
|---|
| 1400 | awr->awar(AWAR_BEST_PARSIMONY)->write_int(awr->awar(AWAR_PARSIMONY)->read_int()); |
|---|
| 1401 | |
|---|
| 1402 | AWT_canvas *ntw = (AWT_canvas*)cl_ntw; |
|---|
| 1403 | ntw->refresh(); |
|---|
| 1404 | } |
|---|
| 1405 | |
|---|
| 1406 | /****************************************************** |
|---|
| 1407 | |
|---|
| 1408 | ******************************************************/ |
|---|
| 1409 | |
|---|
| 1410 | static void pars_start_cb(AW_window *aw_parent, AW_CL cd_adfiltercbstruct) { |
|---|
| 1411 | AW_root *awr = aw_parent->get_root(); |
|---|
| 1412 | GB_begin_transaction(GLOBAL_gb_main); |
|---|
| 1413 | { |
|---|
| 1414 | GB_ERROR error = pars_check_size(awr); |
|---|
| 1415 | if (error){ |
|---|
| 1416 | if (!aw_ask_sure("This program will need a lot of computer memory\n" |
|---|
| 1417 | " (Hint: the use of a filter often helps)\n" |
|---|
| 1418 | "Do you want to continue?")) { |
|---|
| 1419 | GB_commit_transaction(GLOBAL_gb_main); |
|---|
| 1420 | return; |
|---|
| 1421 | } |
|---|
| 1422 | } |
|---|
| 1423 | } |
|---|
| 1424 | |
|---|
| 1425 | |
|---|
| 1426 | AW_window_menu_modes *awm = new AW_window_menu_modes(); |
|---|
| 1427 | awm->init(awr,"ARB_PARSIMONY", "ARB_PARSIMONY", 400,200); |
|---|
| 1428 | |
|---|
| 1429 | AW_gc_manager aw_gc_manager = 0; |
|---|
| 1430 | GLOBAL_NT->tree = PARS_generate_tree(awr); |
|---|
| 1431 | |
|---|
| 1432 | AWT_canvas *ntw; |
|---|
| 1433 | { |
|---|
| 1434 | AP_tree_sort old_sort_type = GLOBAL_NT->tree->tree_sort; |
|---|
| 1435 | GLOBAL_NT->tree->set_tree_type(AP_LIST_SIMPLE); // avoid NDS warnings during startup |
|---|
| 1436 | ntw = new AWT_canvas(GLOBAL_gb_main, (AW_window *)awm, GLOBAL_NT->tree, aw_gc_manager, AWAR_TREE); |
|---|
| 1437 | GLOBAL_NT->tree->set_tree_type(old_sort_type); |
|---|
| 1438 | } |
|---|
| 1439 | |
|---|
| 1440 | { |
|---|
| 1441 | aw_openstatus("load tree"); |
|---|
| 1442 | NT_reload_tree_event(awr,ntw,GB_TRUE); // load first tree and set delete callbacks |
|---|
| 1443 | if (!GLOBAL_NT->tree->tree_root) { |
|---|
| 1444 | aw_closestatus(); |
|---|
| 1445 | aw_popup_exit("I cannot load the selected tree"); |
|---|
| 1446 | } |
|---|
| 1447 | |
|---|
| 1448 | AP_tree_edge::initialize((AP_tree_nlen*)*ap_main->tree_root); // builds edges |
|---|
| 1449 | GLOBAL_NT->tree->tree_root->remove_leafs(ntw->gb_main, AWT_REMOVE_DELETED); |
|---|
| 1450 | |
|---|
| 1451 | adfiltercbstruct *acbs = (adfiltercbstruct*)cd_adfiltercbstruct; |
|---|
| 1452 | NT_tree_init(GLOBAL_NT->tree, acbs); |
|---|
| 1453 | |
|---|
| 1454 | GLOBAL_NT->tree->tree_root->remove_leafs(ntw->gb_main, AWT_REMOVE_DELETED | AWT_REMOVE_NO_SEQUENCE); |
|---|
| 1455 | |
|---|
| 1456 | GB_commit_transaction(ntw->gb_main); |
|---|
| 1457 | aw_status("Calculating inner nodes"); |
|---|
| 1458 | GLOBAL_NT->tree->tree_root->costs(); |
|---|
| 1459 | |
|---|
| 1460 | aw_closestatus(); |
|---|
| 1461 | } |
|---|
| 1462 | |
|---|
| 1463 | awr->awar( AWAR_COLOR_GROUPS_USE)->add_callback( (AW_RCB)NT_recompute_cb, (AW_CL)ntw,0); |
|---|
| 1464 | |
|---|
| 1465 | if (ap_main->commands.add_marked) NT_quick_add(awm,ntw,0); |
|---|
| 1466 | if (ap_main->commands.add_selected) NT_quick_add(awm,ntw,1); |
|---|
| 1467 | if (ap_main->commands.calc_branch_lenths) NT_branch_lengths(awm,ntw); |
|---|
| 1468 | if (ap_main->commands.calc_bootstrap) NT_bootstrap(awm,ntw,0); |
|---|
| 1469 | if (ap_main->commands.quit) pars_exit(awm); |
|---|
| 1470 | |
|---|
| 1471 | GB_transaction dummy(ntw->gb_main); |
|---|
| 1472 | |
|---|
| 1473 | GBDATA *gb_arb_presets = GB_search(ntw->gb_main,"arb_presets", GB_CREATE_CONTAINER); |
|---|
| 1474 | GB_add_callback(gb_arb_presets,GB_CB_CHANGED, (GB_CB)AWT_expose_cb,(int *)ntw); |
|---|
| 1475 | |
|---|
| 1476 | #if defined(DEBUG) |
|---|
| 1477 | AWT_create_debug_menu(awm); |
|---|
| 1478 | #endif // DEBUG |
|---|
| 1479 | |
|---|
| 1480 | awm->create_menu("File", "F", "pars_file.hlp", AWM_ALL ); |
|---|
| 1481 | { |
|---|
| 1482 | awm->insert_menu_topic("print_tree", "Print Tree ...", "P","tree2prt.hlp", AWM_ALL, AWT_popup_print_window, (AW_CL)ntw, 0 ); |
|---|
| 1483 | awm->insert_menu_topic( "quit", "Quit", "Q","quit.hlp", AWM_ALL, (AW_CB)PARS_export_cb, (AW_CL)ntw,2); |
|---|
| 1484 | } |
|---|
| 1485 | |
|---|
| 1486 | awm->create_menu("Species", "S", "nt_tree.hlp", AWM_ALL ); |
|---|
| 1487 | { |
|---|
| 1488 | NT_insert_mark_submenus(awm, ntw, 0); |
|---|
| 1489 | |
|---|
| 1490 | } |
|---|
| 1491 | awm->create_menu("Tree", "T", "nt_tree.hlp", AWM_ALL ); |
|---|
| 1492 | { |
|---|
| 1493 | |
|---|
| 1494 | awm->insert_menu_topic( "nds", "NDS (Node Display Setup) ...", "N","props_nds.hlp", AWM_ALL, AW_POPUP, (AW_CL)AWT_create_nds_window, (AW_CL)ntw->gb_main ); |
|---|
| 1495 | |
|---|
| 1496 | awm->insert_separator(); |
|---|
| 1497 | awm->insert_menu_topic("tree_2_xfig", "Edit Tree View using XFIG ...", "E", "tree2file.hlp", AWM_ALL, AWT_popup_tree_export_window, (AW_CL)ntw, 0); |
|---|
| 1498 | awm->insert_menu_topic("tree_print", "Print Tree View to Printer ...", "P", "tree2prt.hlp", AWM_ALL, AWT_popup_print_window, (AW_CL)ntw, 0); |
|---|
| 1499 | awm->insert_separator(); |
|---|
| 1500 | awm->insert_sub_menu("Collapse/Expand Tree", "C"); |
|---|
| 1501 | { |
|---|
| 1502 | awm->insert_menu_topic("tree_group_all", "Group All", "A","tgroupall.hlp", AWM_ALL, (AW_CB)NT_group_tree_cb, (AW_CL)ntw, 0 ); |
|---|
| 1503 | awm->insert_menu_topic("tree_group_not_marked", "Group All Except Marked", "M","tgroupnmrkd.hlp", AWM_ALL, (AW_CB)NT_group_not_marked_cb, (AW_CL)ntw, 0 ); |
|---|
| 1504 | awm->insert_menu_topic("tree_ungroup_all", "Ungroup All", "U","tungroupall.hlp", AWM_ALL, (AW_CB)NT_ungroup_all_cb, (AW_CL)ntw, 0 ); |
|---|
| 1505 | awm->insert_separator(); |
|---|
| 1506 | NT_insert_color_collapse_submenu(awm, ntw); |
|---|
| 1507 | } |
|---|
| 1508 | awm->close_sub_menu(); |
|---|
| 1509 | awm->insert_separator(); |
|---|
| 1510 | awm->insert_sub_menu("Remove Species from Tree", "R"); |
|---|
| 1511 | { |
|---|
| 1512 | awm->insert_menu_topic("tree_remove_deleted", "Remove Zombies", "Z", "trm_del.hlp", AWM_ALL, (AW_CB)NT_remove_leafs, (AW_CL)ntw, AWT_REMOVE_DELETED|AWT_REMOVE_BUT_DONT_FREE); |
|---|
| 1513 | awm->insert_menu_topic("tree_remove_marked", "Remove Marked", "M", "trm_mrkd.hlp", AWM_ALL, (AW_CB)NT_remove_leafs, (AW_CL)ntw, AWT_REMOVE_MARKED|AWT_REMOVE_BUT_DONT_FREE); |
|---|
| 1514 | awm->insert_menu_topic("tree_keep_marked", "Keep Marked", "K", "tkeep_mrkd.hlp", AWM_ALL, (AW_CB)NT_remove_leafs, (AW_CL)ntw, AWT_REMOVE_NOT_MARKED|AWT_REMOVE_DELETED|AWT_REMOVE_BUT_DONT_FREE); |
|---|
| 1515 | } |
|---|
| 1516 | awm->close_sub_menu(); |
|---|
| 1517 | awm->insert_sub_menu("Add Species to Tree", "A"); |
|---|
| 1518 | { |
|---|
| 1519 | awm->insert_menu_topic("add_marked", "Add Marked Species", "M", "pa_quick.hlp", AWM_ALL, (AW_CB)NT_quick_add, (AW_CL)ntw, 0); |
|---|
| 1520 | awm->insert_menu_topic("add_marked_nni", "Add Marked Species + Local Optimization (NNI)", "N", "pa_add.hlp", AWM_ALL, (AW_CB)NT_add, (AW_CL)ntw, 0); |
|---|
| 1521 | awm->insert_menu_topic("rm_add_marked", "Remove & Add Marked Species", "R", "pa_add.hlp", AWM_ALL, (AW_CB)NT_rquick_add, (AW_CL)ntw, 0); |
|---|
| 1522 | awm->insert_menu_topic("rm_add_marked_nni|", "Remove & Add Marked + Local Optimization (NNI)", "L", "pa_add.hlp", AWM_ALL, (AW_CB)NT_radd, (AW_CL)ntw, 0); |
|---|
| 1523 | awm->insert_separator(); |
|---|
| 1524 | awm->insert_menu_topic("add_marked_partial", "Add Marked Partial Species", "P", "pa_partial.hlp", AWM_ALL, NT_partial_add, (AW_CL)ntw, (AW_CL)0); |
|---|
| 1525 | awm->insert_separator(); |
|---|
| 1526 | awm->insert_menu_topic("add_selected", "Add Selected Species", "S", "pa_quick_sel.hlp", AWM_ALL, (AW_CB)NT_quick_add, (AW_CL)ntw, 1); |
|---|
| 1527 | awm->insert_menu_topic("add_selected_nni", "Add Selected Species + Local Optimization (NNI)", "O", "pa_add_sel.hlp", AWM_ALL, (AW_CB)NT_add, (AW_CL)ntw, 1); |
|---|
| 1528 | } |
|---|
| 1529 | awm->close_sub_menu(); |
|---|
| 1530 | awm->insert_separator(); |
|---|
| 1531 | awm->insert_sub_menu("Tree Optimization", "O"); |
|---|
| 1532 | { |
|---|
| 1533 | awm->insert_menu_topic("nni", "Local Optimization (NNI) of Marked Visible Nodes", "L","", AWM_ALL, (AW_CB)NT_recursiveNNI, (AW_CL)ntw, 0 ); |
|---|
| 1534 | awm->insert_menu_topic("kl_optimization", "Global Optimization of Marked Visible Nodes", "G","pa_optimizer.hlp", AWM_ALL, (AW_CB)NT_optimize, (AW_CL)ntw, 0 ); |
|---|
| 1535 | } |
|---|
| 1536 | awm->close_sub_menu(); |
|---|
| 1537 | awm->insert_menu_topic("reset", "Reset optimal parsimony", "s", "", AWM_ALL, (AW_CB)pars_reset_optimal_parsimony, (AW_CL)ntw, 0); |
|---|
| 1538 | awm->insert_separator(); |
|---|
| 1539 | awm->insert_menu_topic("beautify_tree", "Beautify Tree", "B", "resorttree.hlp", AWM_ALL, (AW_CB)NT_resort_tree_cb, (AW_CL)ntw, 0); |
|---|
| 1540 | awm->insert_menu_topic("calc_branch_lenths", "Calculate Branch Lengths", "L", "pa_branchlengths.hlp", AWM_ALL, (AW_CB)NT_branch_lengths, (AW_CL)ntw, 0); |
|---|
| 1541 | awm->insert_separator(); |
|---|
| 1542 | awm->insert_menu_topic("calc_upper_bootstrap_indep", "Calculate Upper Bootstrap Limit (dependent NNI)", "d", "pa_bootstrap.hlp", AWM_ALL, (AW_CB)NT_bootstrap, (AW_CL)ntw, 0); |
|---|
| 1543 | awm->insert_menu_topic("calc_upper_bootstrap_dep", "Calculate Upper Bootstrap Limit (independent NNI)", "i", "pa_bootstrap.hlp", AWM_ALL, (AW_CB)NT_bootstrap, (AW_CL)ntw, 1); |
|---|
| 1544 | awm->insert_menu_topic("tree_remove_remark", "Remove Bootstrap Values", "V", "trm_boot.hlp", AWM_ALL, (AW_CB)NT_remove_bootstrap, (AW_CL)ntw, 0); |
|---|
| 1545 | } |
|---|
| 1546 | |
|---|
| 1547 | #if defined(TEST_FUNCTIONS) |
|---|
| 1548 | init_TEST_menu(awm,ntw); |
|---|
| 1549 | #endif // TEST_FUNCTIONS |
|---|
| 1550 | |
|---|
| 1551 | awm->create_menu("Properties","r","properties.hlp", AWM_ALL); |
|---|
| 1552 | { |
|---|
| 1553 | awm->insert_menu_topic("props_menu", "Menu: Colors and Fonts ...", "M", "props_frame.hlp", AWM_ALL, AW_POPUP,(AW_CL)AW_preset_window, 0); |
|---|
| 1554 | awm->insert_menu_topic("props_tree", "Tree: Colors and Fonts ...", "C", "pars_props_data.hlp", AWM_ALL, AW_POPUP,(AW_CL)AW_create_gc_window, (AW_CL)aw_gc_manager ); |
|---|
| 1555 | awm->insert_menu_topic("props_tree2", "Tree: Settings ...", "T", "nt_tree_settings.hlp", AWM_ALL, AW_POPUP,(AW_CL)NT_create_tree_setting, (AW_CL)ntw ); |
|---|
| 1556 | awm->insert_menu_topic("props_kl", "KERN. LIN ...", "K", "kernlin.hlp", AWM_ALL, AW_POPUP,(AW_CL)create_kernighan_window, 0); |
|---|
| 1557 | awm->insert_menu_topic("save_props", "Save Defaults (in ~/.arb_prop/pars.arb)", "D", "savedef.hlp", AWM_ALL, (AW_CB)AW_save_defaults, 0, 0); |
|---|
| 1558 | } |
|---|
| 1559 | awm->button_length(5); |
|---|
| 1560 | |
|---|
| 1561 | awm->create_menu("ETC","E","nt_etc.hlp", AWM_ALL); |
|---|
| 1562 | { |
|---|
| 1563 | awm->insert_menu_topic("reset_logical_zoom", "Reset Logical Zoom", "L","rst_log_zoom.hlp", AWM_ALL, (AW_CB)NT_reset_lzoom_cb, (AW_CL)ntw, 0 ); |
|---|
| 1564 | awm->insert_menu_topic("reset_physical_zoom", "Reset Physical Zoom", "P","rst_phys_zoom.hlp",AWM_ALL, (AW_CB)NT_reset_pzoom_cb, (AW_CL)ntw, 0 ); |
|---|
| 1565 | } |
|---|
| 1566 | |
|---|
| 1567 | awm->insert_help_topic("How to use Help", "H", "help.hlp", AWM_ALL, (AW_CB)AW_POPUP_HELP, (AW_CL)"help.hlp", 0); |
|---|
| 1568 | awm->insert_help_topic("ARB Help", "A", "arb.hlp", AWM_ALL, (AW_CB)AW_POPUP_HELP, (AW_CL)"arb.hlp", 0); |
|---|
| 1569 | awm->insert_help_topic("ARB PARSIMONY Help", "N", "arb_pars.hlp", AWM_ALL, (AW_CB)AW_POPUP_HELP, (AW_CL)"arb_pars.hlp", 0); |
|---|
| 1570 | |
|---|
| 1571 | awm->create_mode("select.bitmap", "mode_select.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_SELECT); |
|---|
| 1572 | awm->create_mode("mark.bitmap", "mode_mark.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_MARK); |
|---|
| 1573 | awm->create_mode("group.bitmap", "mode_group.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_GROUP); |
|---|
| 1574 | awm->create_mode("pzoom.bitmap", "mode_pzoom.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_ZOOM); |
|---|
| 1575 | awm->create_mode("lzoom.bitmap", "mode_lzoom.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_LZOOM); |
|---|
| 1576 | awm->create_mode("swap.bitmap", "mode_swap.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_SWAP); |
|---|
| 1577 | awm->create_mode("move.bitmap", "mode_move.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_MOVE); |
|---|
| 1578 | #ifdef NNI_MODES |
|---|
| 1579 | awm->create_mode("nearestn.bitmap", "mode_nni.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_NNI); |
|---|
| 1580 | awm->create_mode("kernlin.bitmap", "mode_kernlin.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_KERNINGHAN); |
|---|
| 1581 | awm->create_mode("optimize.bitmap", "mode_optimize.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_OPTIMIZE); |
|---|
| 1582 | #endif // NNI_MODES |
|---|
| 1583 | awm->create_mode("setroot.bitmap", "mode_set_root.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_SETROOT); |
|---|
| 1584 | awm->create_mode("reset.bitmap", "mode_reset.hlp", AWM_ALL, (AW_CB)nt_mode_event, (AW_CL)ntw, (AW_CL)AWT_MODE_RESET); |
|---|
| 1585 | |
|---|
| 1586 | awm->at(5,2); |
|---|
| 1587 | awm->auto_space(0,-2); |
|---|
| 1588 | awm->shadow_width(1); |
|---|
| 1589 | |
|---|
| 1590 | |
|---|
| 1591 | int db_treex,db_treey; |
|---|
| 1592 | awm->get_at_position( &db_treex,&db_treey ); |
|---|
| 1593 | awm->callback(AW_POPUP_HELP,(AW_CL)"nt_tree_select.hlp"); |
|---|
| 1594 | awm->button_length(16); |
|---|
| 1595 | awm->help_text("nt_tree_select.hlp"); |
|---|
| 1596 | awm->create_button(0,AWAR_TREE); |
|---|
| 1597 | |
|---|
| 1598 | |
|---|
| 1599 | int db_stackx,db_stacky; |
|---|
| 1600 | awm->label_length(8); |
|---|
| 1601 | awm->label("Stored"); |
|---|
| 1602 | awm->get_at_position( &db_stackx,&db_stacky ); |
|---|
| 1603 | awm->button_length(6); |
|---|
| 1604 | awm->callback( AW_POPUP_HELP, (AW_CL)"ap_stack.hlp"); |
|---|
| 1605 | awm->help_text("ap_stack.hlp"); |
|---|
| 1606 | awm->create_button(0,AWAR_STACKPOINTER); |
|---|
| 1607 | |
|---|
| 1608 | int db_parsx,db_parsy; |
|---|
| 1609 | awm->label_length(14); |
|---|
| 1610 | awm->label("Current Pars:"); |
|---|
| 1611 | awm->get_at_position( &db_parsx,&db_parsy ); |
|---|
| 1612 | |
|---|
| 1613 | awm->button_length(10); |
|---|
| 1614 | awm->create_button(0,AWAR_PARSIMONY); |
|---|
| 1615 | |
|---|
| 1616 | awm->button_length(0); |
|---|
| 1617 | |
|---|
| 1618 | awm->callback((AW_CB)NT_jump_cb,(AW_CL)ntw,1); |
|---|
| 1619 | awm->help_text("tr_jump.hlp"); |
|---|
| 1620 | awm->create_button("JUMP","#pjump.bitmap",0); |
|---|
| 1621 | |
|---|
| 1622 | awm->callback(AW_POPUP_HELP,(AW_CL)"arb_pars.hlp"); |
|---|
| 1623 | awm->help_text("help.hlp"); |
|---|
| 1624 | awm->create_button("HELP","HELP","H"); |
|---|
| 1625 | |
|---|
| 1626 | awm->at_newline(); |
|---|
| 1627 | |
|---|
| 1628 | awm->button_length(8); |
|---|
| 1629 | awm->at_x(db_stackx); |
|---|
| 1630 | awm->callback((AW_CB1)AP_user_pop_cb,(AW_CL)ntw); |
|---|
| 1631 | awm->help_text("ap_stack.hlp"); |
|---|
| 1632 | awm->create_button("POP","RESTORE",0); |
|---|
| 1633 | |
|---|
| 1634 | awm->button_length(6); |
|---|
| 1635 | awm->callback((AW_CB1)AP_user_push_cb,(AW_CL)ntw); |
|---|
| 1636 | awm->help_text("ap_stack.hlp"); |
|---|
| 1637 | awm->create_button("PUSH", "STORE",0); |
|---|
| 1638 | |
|---|
| 1639 | awm->button_length(7); |
|---|
| 1640 | |
|---|
| 1641 | awm->at_x(db_treex); |
|---|
| 1642 | awm->callback((AW_CB)NT_set_tree_style,(AW_CL)ntw,(AW_CL)AP_TREE_RADIAL); |
|---|
| 1643 | awm->help_text("tr_type_radial.hlp"); |
|---|
| 1644 | awm->create_button("RADIAL_TREE", "#radial.bitmap",0); |
|---|
| 1645 | |
|---|
| 1646 | awm->callback((AW_CB)NT_set_tree_style,(AW_CL)ntw,(AW_CL)AP_TREE_NORMAL); |
|---|
| 1647 | awm->help_text("tr_type_list.hlp"); |
|---|
| 1648 | awm->create_button("LIST_TREE", "#list.bitmap",0); |
|---|
| 1649 | |
|---|
| 1650 | awm->at_x(db_parsx); |
|---|
| 1651 | awm->label_length(14); |
|---|
| 1652 | awm->label("Optimal Pars:"); |
|---|
| 1653 | |
|---|
| 1654 | awm->button_length(10); |
|---|
| 1655 | awm->create_button(0,AWAR_BEST_PARSIMONY); |
|---|
| 1656 | |
|---|
| 1657 | awm->at_newline(); |
|---|
| 1658 | |
|---|
| 1659 | { |
|---|
| 1660 | AW_at_maxsize maxSize; // store size (so AWAR_FOOTER does not affect min. window size) |
|---|
| 1661 | maxSize.store(awm->_at); |
|---|
| 1662 | awm->button_length(AWAR_FOOTER_MAX_LEN); |
|---|
| 1663 | awm->create_button(0,AWAR_FOOTER); |
|---|
| 1664 | awm->at_newline(); |
|---|
| 1665 | maxSize.restore(awm->_at); |
|---|
| 1666 | } |
|---|
| 1667 | |
|---|
| 1668 | // awm->button_length(AWAR_FOOTER_MAX_LEN); |
|---|
| 1669 | // awm->create_button(0,AWAR_FOOTER); |
|---|
| 1670 | |
|---|
| 1671 | // awm->at_newline(); |
|---|
| 1672 | awm->get_at_position( &db_treex,&db_treey ); |
|---|
| 1673 | awm->set_info_area_height( db_treey+6 ); |
|---|
| 1674 | |
|---|
| 1675 | awm->set_bottom_area_height( 0 ); |
|---|
| 1676 | awm->set_focus_callback((AW_CB)PA_focus_cb,(AW_CL)ntw->gb_main,0); |
|---|
| 1677 | |
|---|
| 1678 | aw_parent->hide(); // hide parent |
|---|
| 1679 | awm->show(); |
|---|
| 1680 | |
|---|
| 1681 | AP_user_push_cb(aw_parent, ntw); // push initial tree |
|---|
| 1682 | } |
|---|
| 1683 | |
|---|
| 1684 | static AW_window *create_pars_init_window(AW_root *awr) |
|---|
| 1685 | { |
|---|
| 1686 | AW_window_simple *aws = new AW_window_simple; |
|---|
| 1687 | aws->init( awr, "PARS_PROPS", "SET PARSIMONY OPTIONS"); |
|---|
| 1688 | aws->load_xfig("pars/init.fig"); |
|---|
| 1689 | |
|---|
| 1690 | aws->button_length( 10 ); |
|---|
| 1691 | aws->label_length( 10 ); |
|---|
| 1692 | |
|---|
| 1693 | aws->callback(pars_exit); |
|---|
| 1694 | aws->at("close"); |
|---|
| 1695 | aws->create_button("ABORT","ABORT","A"); |
|---|
| 1696 | |
|---|
| 1697 | aws->callback(AW_POPUP_HELP,(AW_CL)"arb_pars_init.hlp"); |
|---|
| 1698 | aws->at("help"); |
|---|
| 1699 | aws->create_button("HELP","HELP","H"); |
|---|
| 1700 | |
|---|
| 1701 | aws->at("filter"); |
|---|
| 1702 | adfiltercbstruct *filtercd = awt_create_select_filter(aws->get_root(),GLOBAL_gb_main,AWAR_FILTER_NAME); |
|---|
| 1703 | aws->callback(AW_POPUP, (AW_CL)awt_create_select_filter_win, (AW_CL)filtercd); |
|---|
| 1704 | aws->create_button("SELECT_FILTER",AWAR_FILTER_NAME); |
|---|
| 1705 | |
|---|
| 1706 | aws->callback(pars_start_cb, (AW_CL)filtercd); |
|---|
| 1707 | aws->at("go"); |
|---|
| 1708 | aws->create_button("GO","GO","G"); |
|---|
| 1709 | |
|---|
| 1710 | aws->at("alignment"); |
|---|
| 1711 | awt_create_selection_list_on_ad(GLOBAL_gb_main,(AW_window *)aws,AWAR_ALIGNMENT,"*="); |
|---|
| 1712 | |
|---|
| 1713 | aws->at("tree"); |
|---|
| 1714 | awt_create_selection_list_on_trees(GLOBAL_gb_main,(AW_window *)aws,AWAR_TREE); |
|---|
| 1715 | |
|---|
| 1716 | awt_csp = new AWT_csp(GLOBAL_gb_main,awr,"tmp/pars/csp/name"); |
|---|
| 1717 | |
|---|
| 1718 | aws->at("weights"); |
|---|
| 1719 | aws->callback(AW_POPUP,(AW_CL)create_csp_window,(AW_CL)awt_csp); |
|---|
| 1720 | aws->sens_mask(AWM_EXP); |
|---|
| 1721 | aws->create_button("SELECT_CSP","tmp/pars/csp/name"); |
|---|
| 1722 | aws->sens_mask(AWM_ALL); |
|---|
| 1723 | |
|---|
| 1724 | return (AW_window *)aws; |
|---|
| 1725 | } |
|---|
| 1726 | |
|---|
| 1727 | static void create_parsimony_variables(AW_root *aw_root, AW_default def) |
|---|
| 1728 | { |
|---|
| 1729 | // parsimony |
|---|
| 1730 | #if 0 |
|---|
| 1731 | aw_root->awar_float("genetic/m_rate",0,def); |
|---|
| 1732 | aw_root->awar_int("genetic/input_1",0,def); |
|---|
| 1733 | aw_root->awar_int("genetic/input_2",0,def); |
|---|
| 1734 | aw_root->awar_float("genetic/input_3",0,def); |
|---|
| 1735 | aw_root->awar_float("genetic/input_4",0,def); |
|---|
| 1736 | aw_root->awar_float("genetic/input_5",0,def); |
|---|
| 1737 | aw_root->awar_float("genetic/input_6",0,def); |
|---|
| 1738 | aw_root->awar_float("genetic/input_7",0,def); |
|---|
| 1739 | aw_root->awar_float("genetic/input_8",0,def); |
|---|
| 1740 | aw_root->awar_float("genetic/input_9",0,def); |
|---|
| 1741 | aw_root->awar_float("genetic/input_10",0,def); |
|---|
| 1742 | aw_root->awar_float("genetic/input_11",0,def); |
|---|
| 1743 | aw_root->awar_int("genetic/out_1",0,def); |
|---|
| 1744 | aw_root->awar_float("genetic/out_2",0,def); |
|---|
| 1745 | aw_root->awar_float("genetic/out_3",0,def); |
|---|
| 1746 | aw_root->awar_float("genetic/out_4",0,def); |
|---|
| 1747 | aw_root->awar_float("genetic/out_5",0,def); |
|---|
| 1748 | aw_root->awar_float("genetic/out_6",0,def); |
|---|
| 1749 | aw_root->awar_float("genetic/out_7",0,def); |
|---|
| 1750 | aw_root->awar_float("genetic/out_8",0,def); |
|---|
| 1751 | #endif |
|---|
| 1752 | // kernighan |
|---|
| 1753 | |
|---|
| 1754 | aw_root->awar_float("genetic/kh/nodes",1.7,def); |
|---|
| 1755 | aw_root->awar_int("genetic/kh/maxdepth",15,def); |
|---|
| 1756 | aw_root->awar_int("genetic/kh/incdepth",5,def); |
|---|
| 1757 | |
|---|
| 1758 | aw_root->awar_int("genetic/kh/static/enable",1,def); |
|---|
| 1759 | aw_root->awar_int("genetic/kh/static/depth0",2,def); |
|---|
| 1760 | aw_root->awar_int("genetic/kh/static/depth1",2,def); |
|---|
| 1761 | aw_root->awar_int("genetic/kh/static/depth2",2,def); |
|---|
| 1762 | aw_root->awar_int("genetic/kh/static/depth3",2,def); |
|---|
| 1763 | aw_root->awar_int("genetic/kh/static/depth4",1,def); |
|---|
| 1764 | |
|---|
| 1765 | aw_root->awar_int("genetic/kh/dynamic/enable",1,def); |
|---|
| 1766 | aw_root->awar_int("genetic/kh/dynamic/start",100,def); |
|---|
| 1767 | aw_root->awar_int("genetic/kh/dynamic/maxx",6,def); |
|---|
| 1768 | aw_root->awar_int("genetic/kh/dynamic/maxy",150,def); |
|---|
| 1769 | |
|---|
| 1770 | aw_root->awar_int("genetic/kh/function_type",AP_QUADRAT_START,def); |
|---|
| 1771 | |
|---|
| 1772 | awt_create_dtree_awars(aw_root,def); |
|---|
| 1773 | } |
|---|
| 1774 | |
|---|
| 1775 | static void pars_create_all_awars(AW_root *awr, AW_default aw_def) |
|---|
| 1776 | { |
|---|
| 1777 | awr->awar_string(AWAR_SPECIES_NAME, "", GLOBAL_gb_main); |
|---|
| 1778 | awr->awar_string(AWAR_FOOTER, "", aw_def); |
|---|
| 1779 | awr->awar_string(AWAR_FILTER_NAME, "none", GLOBAL_gb_main); |
|---|
| 1780 | |
|---|
| 1781 | { |
|---|
| 1782 | GB_transaction ta(GLOBAL_gb_main); |
|---|
| 1783 | char *dali = GBT_get_default_alignment(GLOBAL_gb_main); |
|---|
| 1784 | |
|---|
| 1785 | awr->awar_string( AWAR_ALIGNMENT,dali ,GLOBAL_gb_main )->write_string(dali); |
|---|
| 1786 | free(dali); |
|---|
| 1787 | } |
|---|
| 1788 | |
|---|
| 1789 | awt_set_awar_to_valid_filter_good_for_tree_methods(GLOBAL_gb_main,awr,AWAR_FILTER_NAME); |
|---|
| 1790 | |
|---|
| 1791 | awr->awar_string(AWAR_FILTER_FILTER,"" ,GLOBAL_gb_main); |
|---|
| 1792 | awr->awar_string(AWAR_FILTER_ALIGNMENT,"" ,aw_def) ; |
|---|
| 1793 | awr->awar (AWAR_FILTER_ALIGNMENT) ->map(AWAR_ALIGNMENT); |
|---|
| 1794 | |
|---|
| 1795 | awr->awar_string( "tmp/pars/csp/alignment",0 ,aw_def ); |
|---|
| 1796 | awr->awar("tmp/pars/csp/alignment")->map(AWAR_ALIGNMENT); |
|---|
| 1797 | |
|---|
| 1798 | awr->awar_int( AWAR_PARS_TYPE,PARS_WAGNER ,GLOBAL_gb_main ); |
|---|
| 1799 | |
|---|
| 1800 | { |
|---|
| 1801 | GB_transaction ta(GLOBAL_gb_main); |
|---|
| 1802 | GBDATA *gb_tree_name = GB_search(GLOBAL_gb_main,AWAR_TREE,GB_STRING); |
|---|
| 1803 | char *tree_name = GB_read_string(gb_tree_name); |
|---|
| 1804 | |
|---|
| 1805 | awr->awar_string( AWAR_TREE,0 ,aw_def )->write_string(tree_name); |
|---|
| 1806 | free(tree_name); |
|---|
| 1807 | } |
|---|
| 1808 | |
|---|
| 1809 | awr->awar_int(AWAR_PARSIMONY, 0, aw_def); |
|---|
| 1810 | awr->awar_int(AWAR_BEST_PARSIMONY, 0, aw_def); |
|---|
| 1811 | awr->awar_int(AWAR_STACKPOINTER, 0, aw_def); |
|---|
| 1812 | |
|---|
| 1813 | create_parsimony_variables(awr, GLOBAL_gb_main); |
|---|
| 1814 | create_nds_vars(awr,aw_def,GLOBAL_gb_main); |
|---|
| 1815 | |
|---|
| 1816 | #if defined(DEBUG) |
|---|
| 1817 | AWT_create_db_browser_awars(awr, aw_def); |
|---|
| 1818 | #endif // DEBUG |
|---|
| 1819 | |
|---|
| 1820 | GB_ERROR error = ARB_init_global_awars(awr, aw_def, GLOBAL_gb_main); |
|---|
| 1821 | if (error) aw_message(error); |
|---|
| 1822 | } |
|---|
| 1823 | |
|---|
| 1824 | static AW_root *AD_map_viewer_aw_root = 0; |
|---|
| 1825 | |
|---|
| 1826 | void AD_map_viewer(GBDATA *gb_species, AD_MAP_VIEWER_TYPE vtype) { |
|---|
| 1827 | if (vtype == ADMVT_SELECT && AD_map_viewer_aw_root && gb_species) { |
|---|
| 1828 | AD_map_viewer_aw_root->awar(AWAR_SPECIES_NAME)->write_string(GBT_read_name(gb_species)); |
|---|
| 1829 | } |
|---|
| 1830 | } |
|---|
| 1831 | |
|---|
| 1832 | int main(int argc, char **argv) |
|---|
| 1833 | { |
|---|
| 1834 | AW_root *aw_root; |
|---|
| 1835 | AW_default aw_default; |
|---|
| 1836 | AW_window *aww; |
|---|
| 1837 | |
|---|
| 1838 | aw_initstatus(); |
|---|
| 1839 | |
|---|
| 1840 | aw_root = new AW_root; |
|---|
| 1841 | aw_default = aw_root->open_default(".arb_prop/pars.arb"); |
|---|
| 1842 | aw_root->init_variables(aw_default); |
|---|
| 1843 | aw_root->init_root("ARB_PARS", false); |
|---|
| 1844 | |
|---|
| 1845 | AD_map_viewer_aw_root = aw_root; |
|---|
| 1846 | |
|---|
| 1847 | ap_main = new AP_main; |
|---|
| 1848 | |
|---|
| 1849 | GLOBAL_NT = (NT_global *)calloc(sizeof(NT_global),1); |
|---|
| 1850 | GLOBAL_NT->awr = aw_root; |
|---|
| 1851 | |
|---|
| 1852 | const char *db_server = ":"; |
|---|
| 1853 | |
|---|
| 1854 | while (argc>=2 && argv[1][0] == '-'){ |
|---|
| 1855 | argc--; |
|---|
| 1856 | argv++; |
|---|
| 1857 | if (!strcmp(argv[0],"-quit")){ |
|---|
| 1858 | ap_main->commands.quit = 1; |
|---|
| 1859 | continue; |
|---|
| 1860 | } |
|---|
| 1861 | if (!strcmp(argv[0],"-add_marked")){ |
|---|
| 1862 | ap_main->commands.add_marked = 1; |
|---|
| 1863 | continue; |
|---|
| 1864 | } |
|---|
| 1865 | if (!strcmp(argv[0],"-add_selected")){ |
|---|
| 1866 | ap_main->commands.add_selected = 1; |
|---|
| 1867 | continue; |
|---|
| 1868 | } |
|---|
| 1869 | if (!strcmp(argv[0],"-calc_branchlengths")){ |
|---|
| 1870 | ap_main->commands.calc_branch_lenths = 1; |
|---|
| 1871 | continue; |
|---|
| 1872 | } |
|---|
| 1873 | if (!strcmp(argv[0],"-calc_bootstrap")){ |
|---|
| 1874 | ap_main->commands.calc_bootstrap = 1; |
|---|
| 1875 | continue; |
|---|
| 1876 | } |
|---|
| 1877 | GB_export_errorf("Unknown option '%s'",argv[0]); |
|---|
| 1878 | GB_print_error(); |
|---|
| 1879 | printf(" Options: Meaning:\n" |
|---|
| 1880 | "\n" |
|---|
| 1881 | " -add_marked add marked species (without changing topology)\n" |
|---|
| 1882 | " -add_selected add selected species (without changing topology)\n" |
|---|
| 1883 | " -calc_branchlengths calculate branch lengths only\n" |
|---|
| 1884 | " -calc_bootstrap estimate bootstrap values\n" |
|---|
| 1885 | " -quit quit after performing operations\n" |
|---|
| 1886 | ); |
|---|
| 1887 | |
|---|
| 1888 | exit(-1); |
|---|
| 1889 | } |
|---|
| 1890 | |
|---|
| 1891 | |
|---|
| 1892 | if (argc==2) { |
|---|
| 1893 | db_server = argv[1]; |
|---|
| 1894 | } |
|---|
| 1895 | |
|---|
| 1896 | GLOBAL_gb_main = GBT_open(db_server,"rw",0); |
|---|
| 1897 | if (!GLOBAL_gb_main) aw_popup_exit(GB_await_error()); // exits |
|---|
| 1898 | |
|---|
| 1899 | #if defined(DEBUG) |
|---|
| 1900 | AWT_announce_db_to_browser(GLOBAL_gb_main, GBS_global_string("ARB-database (%s)", db_server)); |
|---|
| 1901 | #endif // DEBUG |
|---|
| 1902 | |
|---|
| 1903 | pars_create_all_awars(aw_root,aw_default); |
|---|
| 1904 | |
|---|
| 1905 | aww = create_pars_init_window(aw_root); |
|---|
| 1906 | aww->show(); |
|---|
| 1907 | |
|---|
| 1908 | aw_root->main_loop(); |
|---|
| 1909 | return EXIT_SUCCESS; |
|---|
| 1910 | } |
|---|
| 1911 | |
|---|
| 1912 | |
|---|