1 | #ifndef PS_CANDIDATE_HXX |
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2 | #define PS_CANDIDATE_HXX |
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3 | |
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4 | #ifndef PS_DEFS_HXX |
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5 | #include "ps_defs.hxx" |
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6 | #endif |
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7 | #ifndef PS_BITMAP_HXX |
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8 | #include "ps_bitmap.hxx" |
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9 | #endif |
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10 | #ifndef PS_FILEBUFFER_HXX |
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11 | #include "ps_filebuffer.hxx" |
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12 | #endif |
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13 | |
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14 | #ifndef _CPP_CLIMITS |
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15 | #include <climits> |
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16 | #endif |
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17 | |
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18 | using namespace std; |
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19 | |
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20 | class PS_Candidate; |
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21 | typedef PS_Candidate* PS_CandidatePtr; |
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22 | typedef SmartPtr<PS_Candidate> PS_CandidateSPtr; |
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23 | |
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24 | struct cmp_candidates |
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25 | { |
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26 | bool operator()(const PS_CandidateSPtr &c1, const PS_CandidateSPtr &c2) const |
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27 | { |
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28 | return &(*c1) < &(*c2); |
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29 | } |
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30 | }; |
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31 | typedef set<PS_CandidateSPtr,cmp_candidates> PS_CandidateSet; |
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32 | typedef PS_CandidateSet::iterator PS_CandidateSetIter; |
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33 | typedef PS_CandidateSet::const_iterator PS_CandidateSetCIter; |
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34 | typedef PS_CandidateSet::reverse_iterator PS_CandidateSetRIter; |
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35 | typedef PS_CandidateSet::const_reverse_iterator PS_CandidateSetCRIter; |
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36 | |
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37 | typedef map<unsigned long,PS_CandidateSPtr> PS_CandidateByGainMap; |
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38 | typedef PS_CandidateByGainMap::iterator PS_CandidateByGainMapIter; |
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39 | typedef PS_CandidateByGainMap::const_iterator PS_CandidateByGainMapCIter; |
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40 | typedef PS_CandidateByGainMap::reverse_iterator PS_CandidateByGainMapRIter; |
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41 | typedef PS_CandidateByGainMap::const_reverse_iterator PS_CandidateByGainMapCRIter; |
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42 | |
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43 | // typedef map<float,PS_CandidateSPtr> PS_CandidateByFillingMap; |
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44 | // typedef PS_CandidateByFillingMap::iterator PS_CandidateByFillingMapIter; |
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45 | // typedef PS_CandidateByFillingMap::const_iterator PS_CandidateByFillingMapCIter; |
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46 | // typedef PS_CandidateByFillingMap::reverse_iterator PS_CandidateByFillingMapRIter; |
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47 | // typedef PS_CandidateByFillingMap::const_reverse_iterator PS_CandidateByFillingMapCRIter; |
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48 | |
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49 | typedef pair<SpeciesID,PS_BitSet::IndexSet> ID2IndexSetPair; |
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50 | typedef set<ID2IndexSetPair> ID2IndexSetSet; |
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51 | typedef ID2IndexSetSet::iterator ID2IndexSetSetIter; |
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52 | typedef ID2IndexSetSet::const_iterator ID2IndexSetSetCIter; |
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53 | typedef ID2IndexSetSet::reverse_iterator ID2IndexSetSetRIter; |
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54 | typedef ID2IndexSetSet::const_reverse_iterator ID2IndexSetSetCRIter; |
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55 | |
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56 | class PS_Candidate { |
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57 | private: |
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58 | PS_Candidate(); |
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59 | PS_Candidate( const PS_Candidate& ); |
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60 | explicit PS_Candidate( float _distance, unsigned long _gain, const PS_NodePtr _ps_node, IDSet &_path, PS_CandidatePtr _parent ) { |
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61 | filling_level = 0.0; |
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62 | depth = ULONG_MAX; |
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63 | distance = _distance; |
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64 | gain = _gain; |
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65 | passes_left = MAX_PASSES; |
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66 | parent = _parent; |
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67 | //source_set = 0; |
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68 | //target_set = 0; |
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69 | false_IDs = 0; |
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70 | one_false_IDs = 0; |
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71 | one_false_IDs_matches = 0; |
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72 | map = 0; |
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73 | node = _ps_node; |
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74 | path = _path; |
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75 | } |
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76 | |
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77 | public: |
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78 | static const unsigned int MAX_PASSES = 3; |
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79 | float filling_level; |
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80 | unsigned long depth; |
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81 | float distance; |
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82 | unsigned long gain; |
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83 | unsigned int passes_left; |
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84 | PS_Candidate *parent; |
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85 | //IDSet *source_set; |
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86 | //IDSet *target_set; |
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87 | //ID2IndexSetSet *false_IDs; |
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88 | unsigned long false_IDs; |
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89 | ID2IDSet *one_false_IDs; |
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90 | unsigned long one_false_IDs_matches; |
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91 | PS_BitMap_Counted *map; |
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92 | IDSet path; |
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93 | PS_NodePtr node; |
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94 | PS_CandidateByGainMap children; |
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95 | |
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96 | unsigned long initFalseIDs( const SpeciesID _min_id, |
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97 | const SpeciesID _max_id, |
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98 | SpeciesID &_min_sets_id, |
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99 | SpeciesID &_max_sets_id ) { |
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100 | // if i already have the set return its size |
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101 | if (one_false_IDs) { |
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102 | // for (ID2IndexSetSetCIter i = false_IDs->begin(); |
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103 | // i != false_IDs->end(); |
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104 | // ++i ) { |
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105 | // if (i->first < _min_sets_id) _min_sets_id = i->first; |
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106 | // if (i->first > _max_sets_id) _max_sets_id = i->first; |
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107 | // if (*i->second.begin() < _min_sets_id) _min_sets_id = *i->second.begin(); |
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108 | // if (*i->second.rbegin() > _max_sets_id) _max_sets_id = *i->second.rbegin(); |
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109 | // countFalses += i->second.size(); |
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110 | // //printf( "\n[%i] (%i)", i->first, i->second.size() ); |
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111 | // } |
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112 | return one_false_IDs->size(); |
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113 | } else { |
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114 | one_false_IDs = new ID2IDSet(); |
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115 | false_IDs = 0; |
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116 | //false_IDs = new ID2IndexSetSet(); |
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117 | PS_BitSet::IndexSet falseIndices; // temp. set to hold IDs of falses per ID |
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118 | // iterate over _min_id .. _max_id range in map |
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119 | for ( SpeciesID id1 = _min_id; |
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120 | id1 <= _max_id; |
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121 | ++id1) { |
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122 | if (map->getCountFor( id1 ) == _max_id+1) continue; // skip ID if its already filled |
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123 | if (id1 < _min_sets_id) _min_sets_id = id1; |
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124 | if (id1 > _max_sets_id) _max_sets_id = id1; |
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125 | map->getFalseIndicesFor( id1, falseIndices ); |
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126 | while ((*(falseIndices.begin()) < id1) && |
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127 | !falseIndices.empty()) falseIndices.erase( *falseIndices.begin() ); |
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128 | if (falseIndices.empty()) continue; |
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129 | if (*falseIndices.begin() < _min_sets_id) _min_sets_id = *falseIndices.begin(); |
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130 | if (*falseIndices.rbegin() > _max_sets_id) _max_sets_id = *falseIndices.rbegin(); |
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131 | // store |
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132 | false_IDs += falseIndices.size(); |
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133 | if (falseIndices.size() == 1) { |
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134 | one_false_IDs->insert( ID2IDPair(id1,*falseIndices.begin()) ); |
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135 | } |
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136 | //false_IDs->insert( ID2IndexSetPair( id1,falseIndices ) ); |
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137 | // print |
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138 | // printf( "\n[%i] (%i) ", id1, falseIndices.size() ); |
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139 | // for ( PS_BitSet::IndexSet::const_iterator i = falseIndices.begin(); |
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140 | // i != falseIndices.end(); |
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141 | // ++i ) { |
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142 | // printf( " %li", *i ); |
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143 | // } |
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144 | } |
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145 | } |
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146 | return one_false_IDs->size(); |
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147 | } |
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148 | |
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149 | unsigned long matchPathOnOneFalseIDs( IDSet &_path ) { |
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150 | unsigned long matches = 0; |
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151 | IDSetCIter path_end = _path.end(); |
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152 | for ( ID2IDSetCIter p = one_false_IDs->begin(); |
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153 | p != one_false_IDs->end(); |
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154 | ++p ) { |
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155 | if (_path.find( p->first ) == path_end) { |
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156 | if (_path.find( p->second ) != path_end) ++matches; |
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157 | } else { |
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158 | if (_path.find( p->second ) == path_end) ++matches; |
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159 | } |
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160 | } |
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161 | return matches; |
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162 | } |
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163 | |
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164 | void decreasePasses() { |
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165 | --passes_left; |
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166 | if (passes_left == 0) { |
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167 | //if (source_set) { delete source_set; source_set = 0; } |
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168 | //if (target_set) { delete target_set; target_set = 0; } |
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169 | //if (false_IDs) { delete false_IDs; false_IDs = 0; } |
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170 | //if (one_false_IDs) { delete one_false_IDs; one_false_IDs = 0; } |
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171 | } |
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172 | } |
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173 | |
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174 | void getParentMap() { |
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175 | if (!parent) return; |
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176 | map = parent->map; // grab parents version of the map |
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177 | parent->map = 0; // unbind parent from map |
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178 | } |
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179 | |
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180 | bool hasChild( PS_NodePtr _ps_node ) const { |
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181 | PS_CandidateByGainMapCIter found = children.end(); |
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182 | for ( PS_CandidateByGainMapCIter child = children.begin(); |
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183 | (child != children.end()) && (found == children.end()); |
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184 | ++child ) { |
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185 | if (child->second->node == _ps_node) found = child; |
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186 | } |
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187 | return (found != children.end()); |
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188 | } |
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189 | |
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190 | bool alreadyUsedNode( const PS_NodePtr _ps_node ) const { |
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191 | if (node.Null()) return false; |
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192 | if (_ps_node == node) { |
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193 | return true; |
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194 | } else { |
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195 | return parent->alreadyUsedNode( _ps_node ); |
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196 | } |
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197 | } |
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198 | |
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199 | int addChild( unsigned long _distance, |
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200 | unsigned long _gain, |
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201 | const PS_NodePtr _node, |
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202 | IDSet &_path ) { |
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203 | PS_CandidateByGainMapIter found = children.find( _gain ); |
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204 | if (found == children.end()) { |
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205 | PS_CandidateSPtr new_child( new PS_Candidate(_distance, _gain, _node, _path, this) ); |
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206 | children[ _gain ] = new_child; |
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207 | return 2; |
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208 | } else if (_distance < found->second->distance) { |
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209 | children.erase( _gain ); |
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210 | PS_CandidateSPtr new_child( new PS_Candidate(_distance, _gain, _node, _path, this) ); |
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211 | children[ _gain ] = new_child; |
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212 | return 1; |
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213 | } |
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214 | return 0; |
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215 | } |
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216 | |
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217 | bool updateBestChild( const unsigned long _gain, |
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218 | const unsigned long _one_false_IDs_matches, |
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219 | const float _filling_level, |
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220 | const PS_NodePtr _node, |
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221 | IDSet &_path ) { |
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222 | if (children.size() == 0) { |
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223 | // no child yet |
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224 | PS_CandidateSPtr new_child( new PS_Candidate(0,_gain,_node,_path,this) ); |
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225 | new_child->depth = depth+1; |
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226 | new_child->filling_level = _filling_level; |
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227 | if (_filling_level >= 100.0) new_child->passes_left = 0; |
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228 | children[ 0 ] = new_child; |
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229 | one_false_IDs_matches = _one_false_IDs_matches; |
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230 | return true; |
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231 | } |
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232 | // return false if new child matches less 'must matches' than best child so far |
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233 | if (_one_false_IDs_matches < one_false_IDs_matches ) return false; |
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234 | // return false if new child matches same 'must matches' but has less total gain |
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235 | if ((_one_false_IDs_matches == one_false_IDs_matches) && |
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236 | (_gain <= children[ 0 ]->gain)) return false; |
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237 | |
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238 | children.clear(); |
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239 | PS_CandidateSPtr new_child( new PS_Candidate(0,_gain,_node,_path,this) ); |
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240 | new_child->depth = depth+1; |
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241 | new_child->filling_level = _filling_level; |
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242 | if (_filling_level >= 100.0) new_child->passes_left = 0; |
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243 | children[ 0 ] = new_child; |
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244 | one_false_IDs_matches = _one_false_IDs_matches; |
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245 | return true; |
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246 | } |
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247 | |
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248 | void reduceChildren( const float _filling_level ) { |
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249 | if (children.size() == 0) return; |
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250 | // prepare |
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251 | unsigned long best_gain = children.rbegin()->first; |
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252 | unsigned long worst_gain = children.begin()->first; |
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253 | unsigned long middle_gain = (best_gain + worst_gain) >> 1; |
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254 | PS_CandidateByGainMapIter middle_child = children.find( middle_gain ); |
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255 | if (middle_child == children.end()) { |
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256 | middle_child = children.lower_bound( middle_gain ); |
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257 | middle_gain = middle_child->first; |
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258 | } |
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259 | PS_CandidateByGainMapIter to_delete = children.end(); |
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260 | // delete unwanted childs depending on filling level |
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261 | if (_filling_level < 50.0) { |
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262 | if (children.size() <= 3) return; |
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263 | for ( PS_CandidateByGainMapIter c = children.begin(); |
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264 | c != children.end(); |
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265 | ++c ) { |
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266 | if (to_delete != children.end()) { |
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267 | children.erase( to_delete ); |
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268 | to_delete = children.end(); |
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269 | } |
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270 | if ((c->first != worst_gain) && |
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271 | (c->first != middle_gain) && |
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272 | (c->first != best_gain)) { |
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273 | to_delete = c; |
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274 | } |
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275 | } |
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276 | } else if (_filling_level < 75.0) { |
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277 | if (children.size() <= 2) return; |
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278 | for ( PS_CandidateByGainMapIter c = children.begin(); |
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279 | c != children.end(); |
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280 | ++c ) { |
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281 | if (to_delete != children.end()) { |
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282 | children.erase( to_delete ); |
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283 | to_delete = children.end(); |
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284 | } |
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285 | if ((c->first != middle_gain) && |
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286 | (c->first != best_gain)) { |
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287 | to_delete = c; |
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288 | } |
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289 | } |
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290 | } else { |
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291 | if (children.size() <= 1) return; |
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292 | for ( PS_CandidateByGainMapIter c = children.begin(); |
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293 | c != children.end(); |
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294 | ++c ) { |
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295 | if (to_delete != children.end()) { |
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296 | children.erase( to_delete ); |
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297 | to_delete = children.end(); |
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298 | } |
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299 | if (c->first != best_gain) { |
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300 | to_delete = c; |
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301 | } |
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302 | } |
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303 | } |
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304 | if (to_delete != children.end()) { |
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305 | children.erase( to_delete ); |
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306 | to_delete = children.end(); |
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307 | } |
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308 | } |
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309 | |
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310 | void printProbes( const SpeciesID _species_count, |
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311 | const unsigned long _depth = 0, |
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312 | const bool _descend = true ) const { |
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313 | for (unsigned long i = 0; i < _depth; ++i) { |
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314 | printf( "| " ); |
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315 | } |
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316 | printf( "\n" ); |
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317 | if (node.Null()) { |
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318 | for (unsigned long i = 0; i < _depth; ++i) { |
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319 | printf( "| " ); |
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320 | } |
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321 | printf( "[%p] depth (%lu) no node\n", this, _depth ); |
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322 | } else if (node->countProbes() == 0) { |
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323 | for (unsigned long i = 0; i < _depth; ++i) { |
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324 | printf( "| " ); |
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325 | } |
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326 | printf( "[%p] depth (%lu) node (%p) no probes\n", this, _depth, &(*node) ); |
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327 | } else { |
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328 | for ( PS_ProbeSetCIter probe = node->getProbesBegin(); |
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329 | probe != node->getProbesEnd(); |
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330 | ++probe ) { |
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331 | for (unsigned long i = 0; i < _depth; ++i) { |
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332 | printf( "| " ); |
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333 | } |
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334 | printf( "[%p] depth (%lu) node (%p) matches (%zu) %u %u\n", |
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335 | this, |
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336 | _depth, |
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337 | &(*node), |
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338 | ((*probe)->quality > 0) ? path.size() : _species_count - path.size(), |
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339 | (*probe)->length, |
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340 | (*probe)->GC_content ); |
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341 | } |
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342 | } |
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343 | fflush( stdout ); |
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344 | |
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345 | if ( _descend) { |
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346 | for ( PS_CandidateByGainMapCRIter child = children.rbegin(); |
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347 | child != children.rend(); |
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348 | ++child ) { |
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349 | child->second->printProbes( _species_count, _depth+1 ); |
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350 | } |
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351 | } |
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352 | |
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353 | } |
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354 | |
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355 | void print ( const unsigned long _depth = 0, |
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356 | const bool _print_one_false_IDs = false, |
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357 | const bool _descend = true ) const { |
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358 | for (unsigned long i = 0; i < _depth; ++i) { |
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359 | printf( "| " ); |
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360 | } |
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361 | printf( "[%p] passes left (%u) filling level (%.5f) distance (%6.2f) gain (%6lu) depth (%3lu) path length (%4zu) ", |
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362 | this, |
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363 | passes_left, |
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364 | filling_level, |
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365 | distance, |
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366 | gain, |
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367 | depth, |
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368 | path.size() ); |
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369 | if (node.Null()) { |
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370 | printf( "node (undefined) children (%2zu) ", children.size() ); |
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371 | } else { |
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372 | printf( "node (%p) children (%2zu) ", &(*node), children.size() ); |
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373 | } |
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374 | // unsigned long count = 0; |
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375 | // for ( ID2IndexSetSetCIter i = false_IDs->begin(); |
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376 | // i != false_IDs->end(); |
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377 | // ++i ) { |
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378 | // count += i->second.size(); |
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379 | // } |
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380 | printf( "(%4lu %4zu)/%lu", one_false_IDs_matches, (one_false_IDs) ? one_false_IDs->size() : 0, false_IDs ); |
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381 | if (_print_one_false_IDs) { |
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382 | printf( "\n" ); |
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383 | for (unsigned long i = 0; i < _depth; ++i) { |
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384 | printf( "| " ); |
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385 | } |
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386 | printf( " one_false_IDs : " ); |
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387 | if (one_false_IDs) { |
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388 | for ( ID2IDSetCIter p = one_false_IDs->begin(); |
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389 | p != one_false_IDs->end(); |
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390 | ++p ) { |
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391 | printf( "(%i %i) ", p->first, p->second ); |
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392 | } |
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393 | } else { |
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394 | printf( "none" ); |
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395 | } |
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396 | } |
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397 | printf( "\n" ); fflush( stdout ); |
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398 | if (_descend) { |
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399 | for ( PS_CandidateByGainMapCRIter child = children.rbegin(); |
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400 | child != children.rend(); |
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401 | ++child ) { |
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402 | child->second->print(_depth+1); |
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403 | } |
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404 | } |
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405 | } |
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406 | |
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407 | void save( PS_FileBuffer *_file, |
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408 | const unsigned long _bits_in_map ) { |
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409 | unsigned long count; |
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410 | // gain |
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411 | _file->put_ulong( gain ); |
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412 | // passes_left |
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413 | _file->put_uint( passes_left ); |
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414 | // false_IDs |
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415 | _file->put_ulong( false_IDs ); |
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416 | // one_false_IDs |
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417 | if (one_false_IDs) { |
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418 | count = one_false_IDs->size(); |
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419 | _file->put_ulong( count ); |
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420 | for ( ID2IDSetCIter p = one_false_IDs->begin(); |
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421 | p != one_false_IDs->end(); |
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422 | ++p ) { |
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423 | _file->put_int( p->first ); |
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424 | _file->put_int( p->second ); |
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425 | } |
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426 | } else { |
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427 | _file->put_ulong( 0 ); |
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428 | } |
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429 | // one_false_IDs_matches |
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430 | _file->put_ulong( one_false_IDs_matches ); |
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431 | // path |
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432 | count = path.size(); |
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433 | _file->put_ulong( count ); |
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434 | for ( IDSetCIter id = path.begin(); |
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435 | id != path.end(); |
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436 | ++id ) { |
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437 | _file->put_int( *id ); |
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438 | } |
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439 | // children |
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440 | count = children.size(); |
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441 | _file->put_ulong( count ); |
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442 | for ( PS_CandidateByGainMapIter child = children.begin(); |
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443 | child != children.end(); |
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444 | ++child ) { |
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445 | child->second->save( _file, _bits_in_map ); |
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446 | } |
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447 | } |
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448 | |
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449 | void load( PS_FileBuffer *_file, |
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450 | const unsigned long _bits_in_map, |
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451 | const PS_NodePtr _root_node ) { |
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452 | unsigned long count; |
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453 | // gain |
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454 | _file->get_ulong( gain ); |
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455 | // passes_left |
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456 | _file->get_uint( passes_left ); |
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457 | // false_IDs & filling_level |
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458 | _file->get_ulong( false_IDs ); |
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459 | filling_level = (float)(_bits_in_map - false_IDs) / _bits_in_map * 100.0; |
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460 | // one_false_IDs |
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461 | SpeciesID id1; |
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462 | SpeciesID id2; |
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463 | _file->get_ulong( count ); |
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464 | one_false_IDs = (count) ? new ID2IDSet() : 0; |
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465 | for ( ; count > 0; --count ) { |
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466 | _file->get_int( id1 ); |
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467 | _file->get_int( id2 ); |
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468 | one_false_IDs->insert( ID2IDPair( id1,id2 ) ); |
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469 | } |
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470 | // one_false_IDs_matches |
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471 | _file->get_ulong( one_false_IDs_matches ); |
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472 | // path & node |
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473 | _file->get_ulong( count ); |
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474 | if (count) node = _root_node; |
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475 | for ( ; count > 0; --count ) { |
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476 | _file->get_int( id1 ); |
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477 | path.insert( id1 ); |
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478 | node = node->getChild( id1 ).second; |
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479 | } |
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480 | // children |
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481 | _file->get_ulong( count ); |
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482 | for ( ; count > 0; --count ) { |
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483 | PS_CandidateSPtr new_child( new PS_Candidate( 0.0 ) ); |
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484 | new_child->depth = depth+1; |
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485 | new_child->parent = this; |
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486 | new_child->load( _file, _bits_in_map, _root_node ); |
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487 | children[ new_child->gain ] = new_child; |
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488 | } |
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489 | } |
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490 | |
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491 | explicit PS_Candidate( float _distance ) { |
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492 | filling_level = 0.0; |
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493 | depth = 0; |
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494 | distance = _distance; |
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495 | gain = 0; |
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496 | passes_left = 0; |
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497 | parent = 0; |
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498 | //source_set = 0; |
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499 | //target_set = 0; |
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500 | false_IDs = 0; |
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501 | one_false_IDs = 0; |
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502 | one_false_IDs_matches = 0; |
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503 | map = 0; |
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504 | node.SetNull(); |
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505 | } |
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506 | ~PS_Candidate() { |
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507 | if (map) delete map; |
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508 | if (one_false_IDs) delete one_false_IDs; |
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509 | //if (false_IDs) delete false_IDs; |
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510 | //if (source_set) delete source_set; |
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511 | //if (target_set) delete target_set; |
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512 | if (path.size() > 0) path.clear(); |
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513 | if (children.size() > 0) children.clear(); |
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514 | } |
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515 | }; |
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516 | |
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517 | #else |
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518 | #error ps_candidate.hxx included twice |
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519 | #endif |
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