| 1 | // =============================================================== // |
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| 2 | // // |
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| 3 | // File : AP_seq_protein.hxx // |
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| 4 | // Purpose : // |
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| 5 | // // |
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| 6 | // Institute of Microbiology (Technical University Munich) // |
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| 7 | // http://www.arb-home.de/ // |
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| 8 | // // |
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| 9 | // =============================================================== // |
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| 10 | |
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| 11 | #ifndef AP_SEQ_PROTEIN_HXX |
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| 12 | #define AP_SEQ_PROTEIN_HXX |
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| 13 | |
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| 14 | #ifndef AP_SEQUENCE_HXX |
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| 15 | #include <AP_sequence.hxx> |
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| 16 | #endif |
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| 17 | |
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| 18 | |
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| 19 | enum AP_PROTEINS { |
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| 20 | APP_ILLEGAL = 0, |
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| 21 | APP_A = (1 << 0), // Ala |
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| 22 | APP_C = (1 << 1), // Cys |
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| 23 | APP_D = (1 << 2), // Asp |
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| 24 | APP_E = (1 << 3), // Glu |
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| 25 | APP_F = (1 << 4), // Phe |
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| 26 | APP_G = (1 << 5), // Gly |
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| 27 | APP_H = (1 << 6), // His |
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| 28 | APP_I = (1 << 7), // Ile |
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| 29 | APP_K = (1 << 8), // Lys |
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| 30 | APP_L = (1 << 9), // Leu |
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| 31 | APP_M = (1 << 10), // Met |
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| 32 | APP_N = (1 << 11), // Asn |
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| 33 | APP_P = (1 << 12), // Pro |
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| 34 | APP_Q = (1 << 13), // Gln |
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| 35 | APP_R = (1 << 14), // Arg |
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| 36 | APP_S = (1 << 15), // Ser |
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| 37 | APP_T = (1 << 16), // Thr |
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| 38 | APP_V = (1 << 17), // Val |
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| 39 | APP_W = (1 << 18), // Trp |
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| 40 | APP_Y = (1 << 19), // Tyr |
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| 41 | |
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| 42 | APP_STAR = (1 << 20), // * |
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| 43 | APP_GAP = (1 << 21), // space (gap) |
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| 44 | |
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| 45 | APP_X = (APP_STAR-1), // Xxx (any real codon) |
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| 46 | |
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| 47 | APP_B = APP_D | APP_N, // Asx ( = Asp | Asn ) |
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| 48 | APP_Z = APP_E | APP_Q, // Glx ( = Glu | Gln ) |
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| 49 | }; |
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| 50 | |
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| 51 | class AP_sequence_protein : public AP_sequence { // derived from a Noncopyable |
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| 52 | AP_PROTEINS *seq_prot; |
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| 53 | |
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| 54 | AP_FLOAT count_weighted_bases() const OVERRIDE; |
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| 55 | void set(const char *isequence) OVERRIDE; |
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| 56 | void unset() OVERRIDE; |
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| 57 | |
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| 58 | public: |
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| 59 | AP_sequence_protein(const AliView *aliview); |
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| 60 | virtual ~AP_sequence_protein() OVERRIDE; |
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| 61 | |
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| 62 | const AP_PROTEINS *get_sequence() const { lazy_load_sequence(); ap_assert(seq_prot); return seq_prot; } |
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| 63 | |
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| 64 | AP_sequence *dup() const OVERRIDE; // used to get the real new element |
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| 65 | AP_FLOAT combine(const AP_sequence* lefts, const AP_sequence *rights, char *mutation_per_site = 0) OVERRIDE; |
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| 66 | void partial_match(const AP_sequence* part, long *overlap, long *penalty) const OVERRIDE; |
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| 67 | }; |
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| 68 | |
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| 69 | |
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| 70 | |
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| 71 | #else |
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| 72 | #error AP_seq_protein.hxx included twice |
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| 73 | #endif // AP_SEQ_PROTEIN_HXX |
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