| 1 | # main topics: |
|---|
| 2 | UP arb.hlp |
|---|
| 3 | UP glossary.hlp |
|---|
| 4 | |
|---|
| 5 | # sub topics: |
|---|
| 6 | #SUB subtopic.hlp |
|---|
| 7 | |
|---|
| 8 | # format described in ../help.readme |
|---|
| 9 | |
|---|
| 10 | |
|---|
| 11 | TITLE Alignment adaption (select species) |
|---|
| 12 | |
|---|
| 13 | Select species to use for alignment adaption |
|---|
| 14 | |
|---|
| 15 | OCCURRENCE ARB_MERGE/TRANSFER SPECIES (Adapt alignment/SELECT) |
|---|
| 16 | |
|---|
| 17 | DESCRIPTION Helps you finding candidates for alignment preservation. |
|---|
| 18 | |
|---|
| 19 | Normally people have inserted new gaps in one of the two databases. |
|---|
| 20 | ARB Merge tries to adapt the alignment. |
|---|
| 21 | |
|---|
| 22 | To be able to do this, you have to specify one or more species or SAIs |
|---|
| 23 | existing in BOTH databases. ARB Merge then creates a column reference list |
|---|
| 24 | and realigns all transferred species according to this list. |
|---|
| 25 | |
|---|
| 26 | Press the 'Find candidates' button to search both databases for candidate |
|---|
| 27 | species/SAIs and rate them. |
|---|
| 28 | |
|---|
| 29 | A list of species/SAIs shows up. The first column contains the name, |
|---|
| 30 | the second column the number of alignments containing data for this species/SAI, |
|---|
| 31 | the third column shows the position-count-difference (see below), |
|---|
| 32 | the fourth column is the score (higher value means better). |
|---|
| 33 | |
|---|
| 34 | The list is sorted by score, i.e. best candidates are listed at the top. |
|---|
| 35 | |
|---|
| 36 | The term 'position-count-difference' is calculated like follows: |
|---|
| 37 | For all alignments the number of non-gaps (i.e. neither '-' nor '.') are counted and |
|---|
| 38 | the differences between these counts are summarized for all alignments. |
|---|
| 39 | Best value is 0, which normally means the sequence data of the species (or the SAI data) |
|---|
| 40 | didn't change. A high value means that species changed data and isn't a good candidate |
|---|
| 41 | for alignment preservation. |
|---|
| 42 | |
|---|
| 43 | To enable this feature, enable the 'Adapt alignment' toggle. |
|---|
| 44 | |
|---|
| 45 | NOTES In our database releases we provide SAIs named 'gaps_...'. |
|---|
| 46 | These SAIs are the best candidates for alignment preservation. |
|---|
| 47 | |
|---|
| 48 | When merging similar databases with many species, searching adapt candidates |
|---|
| 49 | may take a long time. Press KILL in the status window to abort the process. |
|---|
| 50 | |
|---|
| 51 | EXAMPLES None |
|---|
| 52 | |
|---|
| 53 | WARNINGS Calculated SAIs (like MAX_FREQUENCY or POS_VAR_BY_PARSIMONY) show up on top |
|---|
| 54 | but they are normally NO good candidates for preservation. |
|---|
| 55 | |
|---|
| 56 | BUGS No bugs known |
|---|