source: branches/stable/GDE/TREEPUZZLE/README

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treepuzzle

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1TREE-PUZZLE 5.0
2
3TREE-PUZZLE is a computer program to reconstruct phylogenetic trees
4from molecular sequence data by maximum likelihood. It implements a
5fast tree search algorithm, quartet puzzling, that allows analysis of
6large data sets and automatically assigns estimations of support to each
7internal branch. TREE-PUZZLE also computes pairwise maximum likelihood
8distances as well as branch lengths for user specified trees. Branch
9lengths can also be calculated under the clock-assumption. In addition,
10TREE-PUZZLE offers a novel method, likelihood mapping, to investigate
11the support of a hypothesized internal branch without computing an overall
12tree and to visualize the phylogenetic content of a sequence alignment.
13TREE-PUZZLE also conducts a number of statistical tests on the data set
14(chi-square test for homogeneity of base composition, likelihood ratio
15to test the clock hypothesis, Kishino-Hasegawa test). The models of
16substitution provided by TREE-PUZZLE are TN, HKY, F84, SH for
17nucleotides, Dayhoff, JTT, mtREV24, BLOSUM 62, VT, WAG for amino acids,
18and F81 for two-state data. Rate heterogeneity is modelled by a
19discrete Gamma distribution and by allowing invariable sites.
20The corresponding parameters can be inferred from the data set.
21
22INSTALLATION
23
24For compile an intall instructions see INSTALL and doc/manual.html
25
26In most cases on UNIX machines the following should work:
27
28   sh ./configure
29   make
30   make intall
31
32
33
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