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Last change
on this file was
7987,
checked in by westram, 13 years ago
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- support new probe match params introduced in [7986] from ARB_NT (fixes #241)
- Separate expert windows for probe match/design
- create_probe_design_variables
- renamed property-db params to make clear which awars go to props/db
- AWAR_PROBE_ADMIN_PT_SERVER now saved in
- added help for new parameters; fixed help of probe-design-expert; put bonds into own helpfile
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-
Property svn:eol-style set to
native
-
Property svn:keywords set to
Author Date Id Revision
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File size:
1.2 KB
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| 1 | #Please insert up references in the next lines (line starts with keyword UP) |
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| 2 | UP arb.hlp |
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| 3 | UP glossary.hlp |
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| 4 | UP probedesign.hlp |
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| 5 | |
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| 6 | #Please insert subtopic references (line starts with keyword SUB) |
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| 7 | #SUB bonds.hlp |
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| 8 | |
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| 9 | # Hypertext links in helptext can be added like this: LINK{ref.hlp|http://add|bla@domain} |
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| 10 | |
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| 11 | #************* Title of helpfile !! and start of real helpfile ******** |
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| 12 | TITLE Probe design (Expert) |
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| 13 | |
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| 14 | OCCURRENCE ARB_NT/Probes/Design Probes/EXPERT |
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| 15 | |
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| 16 | DESCRIPTION See LINK{bonds.hlp} for upper area. |
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| 17 | |
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| 18 | Define threshold for splitting melting domains: |
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| 19 | |
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| 20 | Type a value to the 'Threshold for Splitting' subwindow. |
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| 21 | This value is subtracted from the mean of all pairing |
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| 22 | values of the potential probe target hybrid. If the |
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| 23 | resulting value is lower than that of a particular |
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| 24 | mispairing, it is assumed that the remaining base paired |
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| 25 | stretches melt independently. The dissociation |
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| 26 | temperature of the whole hybrid is that of the more |
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| 27 | stable part of it. |
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| 28 | |
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| 29 | NOTES None |
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| 30 | |
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| 31 | EXAMPLES None |
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| 32 | |
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| 33 | WARNINGS The criteria used for probe target site ranking are based on |
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| 34 | experimental experience. However, optimum conditions have to be |
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| 35 | determined experimentally for the particular probe target |
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| 36 | hybrids. |
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| 37 | |
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| 38 | BUGS No bugs known |
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