1 | #Please insert up references in the next lines (line starts with keyword UP) |
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2 | UP arb.hlp |
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3 | UP glossary.hlp |
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4 | |
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5 | #Please insert subtopic references (line starts with keyword SUB) |
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6 | #SUB subtopic.hlp |
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7 | |
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8 | # Hypertext links in helptext can be added like this: LINK{ref.hlp|http://add|bla@domain} |
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9 | |
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10 | #************* Title of helpfile !! and start of real helpfile ******** |
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11 | TITLE Select species to use for alignment adaption |
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12 | |
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13 | OCCURRENCE ARB_MERGE/TRANSFER SPECIES (Adapt alignment/SELECT) |
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14 | |
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15 | DESCRIPTION Helps you finding candidates for alignment preservation. |
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16 | |
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17 | Normally people have inserted new gaps in one of the two databases. |
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18 | ARB Merge tries to adapt the alignment. |
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19 | |
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20 | To be able to do this, you have to specify one or more species or SAIs |
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21 | existing in BOTH databases. ARB Merge then creates a column reference list |
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22 | and realigns all transferred species according to this list. |
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23 | |
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24 | Press the 'Find candidates' button to search both databases for candidate |
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25 | species/SAIs and rate them. |
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26 | |
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27 | A list of species/SAIs shows up. The first column contains the name, |
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28 | the second column the number of alignments containing data for this species/SAI, |
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29 | the third column shows the position-count-difference (see below), |
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30 | the fourth column is the score (higher value means better). |
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31 | |
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32 | The list is sorted by score, i.e. best candidates are listed at the top. |
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33 | |
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34 | The term 'position-count-difference' is calculated like follows: |
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35 | For all alignments the number of non-gaps (i.e. neither '-' nor '.') are counted and |
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36 | the differences between these counts are summarized for all alignments. |
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37 | Best value is 0, which normally means the sequence data of the species (or the SAI data) |
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38 | didn't change. A high value means that species changed data and isn't a good candidate |
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39 | for alignment preservation. |
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40 | |
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41 | To enable this feature, enable the 'Adapt alignment' toggle. |
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42 | |
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43 | NOTES In our database releases we provide SAIs named 'gaps_...'. |
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44 | These SAIs are the best candidates for alignment preservation. |
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45 | |
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46 | When merging similar databases with many species, searching adapt candidates |
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47 | may take a long time. Press KILL in the status window to abort the process. |
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48 | |
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49 | EXAMPLES None |
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50 | |
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51 | WARNINGS Calculated SAIs (like MAX_FREQUENCY or POS_VAR_BY_PARSIMONY) show up on top |
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52 | but they are normally NO good candidates for preservation. |
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53 | |
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54 | BUGS No bugs known |
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