| 1 | #Please insert up references in the next lines (line starts with keyword UP) |
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| 2 | UP arb.hlp |
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| 3 | UP glossary.hlp |
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| 4 | UP pa_optimizer.hlp |
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| 5 | |
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| 6 | #Please insert subtopic references (line starts with keyword SUB) |
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| 7 | #SUB subtopic.hlp |
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| 8 | |
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| 9 | # Hypertext links in helptext can be added like this: LINK{ref.hlp|http://add|bla@domain} |
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| 10 | |
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| 11 | #************* Title of helpfile !! and start of real helpfile ******** |
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| 12 | TITLE Calculate Branch Lengths |
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| 13 | |
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| 14 | OCCURRENCE ARB_PARSIMONY/Tree/Calculate Branch Lengths |
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| 15 | |
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| 16 | |
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| 17 | DESCRIPTION Calculates branchlengths for the current tree. |
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| 18 | |
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| 19 | |
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| 20 | SECTION Inner branches |
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| 21 | |
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| 22 | To calculate the lengths of non-terminal branches, branch swapping |
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| 23 | is used on them. |
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| 24 | |
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| 25 | Branch swapping (aka LINK{nni.hlp}) is the most |
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| 26 | atomic operation possible at an inner branch and has as such an effect on |
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| 27 | the overall costs of the tree (i.e. on the LINK{pa_value.hlp}). |
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| 28 | |
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| 29 | That effect is used as branchlength for inner branches. |
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| 30 | |
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| 31 | The branchlength reflects the significance of the branch, i.e. |
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| 32 | |
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| 33 | - the exact topology around SHORT inner branches has little influence |
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| 34 | on the overall tree costs, i.e. the calculated topology does most |
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| 35 | likely NOT reflect the "real phylogentic topology". |
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| 36 | |
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| 37 | - Opposed, the exact topology around LONG inner branches has big influence |
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| 38 | on the overall tree costs, i.e. the calculated topology does most |
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| 39 | likely reflect the "real phylogentic topology". |
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| 40 | |
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| 41 | SECTION Terminal branches |
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| 42 | |
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| 43 | For terminal branches ARB_PARSIMONY checks how much the overall |
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| 44 | tree costs changed by adding this species to the tree. The cost |
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| 45 | gets weighted by the base-count of the species. |
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| 46 | |
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| 47 | i.e. |
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| 48 | - if the species has an identical relative in the tree and is added |
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| 49 | as neighbor of that relative, the resulting branchlength will be zero. |
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| 50 | - if adding the species increases the tree costs by 50 (mutations) and the |
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| 51 | species contains 100 bases, the resulting branchlength will be 0.5 |
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| 52 | |
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| 53 | This does quite accurately reflect the percentage of residues changed |
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| 54 | against the rest of the tree. |
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| 55 | |
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| 56 | SECTION Partial sequences |
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| 57 | |
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| 58 | If you add species with partial sequences as fulllength-species, they |
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| 59 | might group together in subtrees. To avoid that unwanted behavior, |
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| 60 | use LINK{pa_partial.hlp}. |
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| 61 | |
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| 62 | |
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| 63 | SECTION Used terms |
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| 64 | |
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| 65 | - overall tree costs: minimum number of mutation in the tree |
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| 66 | - base-count: without filtered positions. affected by specified weights. |
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| 67 | |
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| 68 | |
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| 69 | EXAMPLES None |
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| 70 | |
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| 71 | WARNINGS None |
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| 72 | |
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| 73 | BUGS No bugs known |
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