| 1 | // =============================================================== // |
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| 2 | // // |
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| 3 | // File : ali_pt.cxx // |
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| 4 | // Purpose : // |
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| 5 | // // |
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| 6 | // Institute of Microbiology (Technical University Munich) // |
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| 7 | // http://www.arb-home.de/ // |
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| 8 | // // |
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| 9 | // =============================================================== // |
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| 10 | |
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| 11 | #include "ali_pt.hxx" |
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| 12 | |
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| 13 | int ALI_PT::init_communication() { |
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| 14 | // Initialize the communication with the pt server |
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| 15 | const char *user = GB_getenvUSER(); |
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| 16 | if (aisc_create(link, PT_MAIN, com, |
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| 17 | MAIN_LOCS, PT_LOCS, locs, |
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| 18 | LOCS_USER, user, |
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| 19 | NULL)) |
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| 20 | { |
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| 21 | return 1; |
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| 22 | } |
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| 23 | return 0; |
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| 24 | } |
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| 25 | |
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| 26 | char *ALI_PT::get_family_member(char *specifiedfamily, unsigned long number) |
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| 27 | { |
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| 28 | char *ptr = specifiedfamily; |
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| 29 | char *end; |
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| 30 | char *buffer, *dest; |
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| 31 | |
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| 32 | while (number > 0 && *ptr != '\0' && *ptr != ';') { |
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| 33 | while (*ptr != '\0' && *ptr != ';' && *ptr != ',') |
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| 34 | ptr++; |
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| 35 | if (*ptr == ',') |
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| 36 | ptr++; |
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| 37 | number--; |
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| 38 | } |
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| 39 | |
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| 40 | if (*ptr != '\0' && *ptr != ';') { |
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| 41 | end = ptr; |
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| 42 | while (*end != '\0' && *end != ',' && *end != ';') |
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| 43 | end++; |
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| 44 | |
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| 45 | buffer = dest = (char *) CALLOC((unsigned int) |
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| 46 | (end - ptr) + 1, sizeof(char)); |
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| 47 | if (buffer == 0) |
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| 48 | ali_fatal_error("Out of memory"); |
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| 49 | |
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| 50 | while (ptr != end) |
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| 51 | *dest++ = *ptr++; |
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| 52 | *dest = '\0'; |
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| 53 | |
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| 54 | return buffer; |
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| 55 | } |
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| 56 | return 0; |
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| 57 | } |
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| 58 | |
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| 59 | char *ALI_PT::get_extension_member(char *specifiedfamily, unsigned long number) |
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| 60 | { |
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| 61 | char *ptr = specifiedfamily; |
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| 62 | char *end; |
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| 63 | char *buffer, *dest; |
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| 64 | |
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| 65 | while (*ptr != '\0' && *ptr != ';') |
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| 66 | ptr++; |
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| 67 | if (*ptr == ';') |
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| 68 | ptr++; |
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| 69 | |
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| 70 | while (number > 0 && *ptr != '\0') { |
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| 71 | while (*ptr != '\0' && *ptr != ',') |
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| 72 | ptr++; |
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| 73 | if (*ptr == ',') |
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| 74 | ptr++; |
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| 75 | number--; |
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| 76 | } |
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| 77 | |
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| 78 | if (*ptr != '\0') { |
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| 79 | end = ptr; |
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| 80 | while (*end != '\0' && *end != ',') |
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| 81 | end++; |
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| 82 | |
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| 83 | buffer = dest = (char *) CALLOC((unsigned int) (end - ptr) + 1, sizeof(char)); |
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| 84 | if (buffer == 0) |
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| 85 | ali_fatal_error("Out of memory"); |
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| 86 | |
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| 87 | while (ptr != end) |
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| 88 | *dest++ = *ptr++; |
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| 89 | *dest = '\0'; |
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| 90 | |
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| 91 | return buffer; |
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| 92 | } |
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| 93 | |
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| 94 | return 0; |
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| 95 | } |
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| 96 | |
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| 97 | |
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| 98 | int ALI_PT::open(char *servername) |
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| 99 | { |
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| 100 | if (arb_look_and_start_server(AISC_MAGIC_NUMBER, servername)) { |
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| 101 | ali_message ("Cannot contact Probe bank server"); |
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| 102 | return -1; |
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| 103 | } |
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| 104 | |
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| 105 | const char *socketid = GBS_read_arb_tcp(servername); |
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| 106 | |
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| 107 | if (!socketid) { |
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| 108 | ali_message(GB_await_error()); |
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| 109 | return -1; |
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| 110 | } |
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| 111 | |
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| 112 | GB_ERROR openerr = NULL; |
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| 113 | link = aisc_open(socketid, com, AISC_MAGIC_NUMBER, &openerr); |
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| 114 | |
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| 115 | if (openerr) { |
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| 116 | ali_message (openerr); |
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| 117 | return -1; |
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| 118 | } |
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| 119 | |
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| 120 | if (!link) { |
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| 121 | ali_message ("Cannot contact Probe bank server "); |
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| 122 | return -1; |
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| 123 | } |
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| 124 | |
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| 125 | if (init_communication()) { |
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| 126 | ali_message ("Cannot contact Probe bank server (2)"); |
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| 127 | return -1; |
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| 128 | } |
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| 129 | |
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| 130 | return 0; |
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| 131 | } |
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| 132 | |
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| 133 | void ALI_PT::close() |
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| 134 | { |
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| 135 | if (link) aisc_close(link, com); |
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| 136 | link = 0; |
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| 137 | } |
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| 138 | |
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| 139 | ALI_PT::ALI_PT(ALI_PT_CONTEXT *context) |
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| 140 | { |
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| 141 | link = 0; |
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| 142 | |
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| 143 | fam_list_max = context->fam_list_max; |
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| 144 | ext_list_max = context->ext_list_max; |
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| 145 | percent_min = context->percent_min; |
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| 146 | matches_min = context->matches_min; |
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| 147 | |
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| 148 | family_list = 0; |
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| 149 | extension_list = 0; |
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| 150 | |
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| 151 | if (context->use_specified_family != 0) { |
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| 152 | mode = SpecifiedMode; |
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| 153 | specified_family = strdup(context->use_specified_family); |
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| 154 | } |
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| 155 | else { |
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| 156 | mode = ServerMode; |
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| 157 | specified_family = 0; |
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| 158 | |
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| 159 | ali_message("Connecting to PT server"); |
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| 160 | if (open(context->servername) != 0) { |
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| 161 | ali_fatal_error("Can't connect to PT server"); |
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| 162 | } |
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| 163 | ali_message("Connection established"); |
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| 164 | } |
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| 165 | } |
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| 166 | |
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| 167 | ALI_PT::~ALI_PT() |
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| 168 | { |
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| 169 | close(); |
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| 170 | |
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| 171 | if (family_list != 0 && !family_list->is_empty()) { |
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| 172 | delete family_list->first(); |
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| 173 | while (family_list->is_next()) |
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| 174 | delete family_list->next(); |
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| 175 | delete family_list; |
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| 176 | } |
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| 177 | if (extension_list != 0 && !extension_list->is_empty()) { |
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| 178 | delete extension_list->first(); |
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| 179 | while (extension_list->is_next()) |
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| 180 | delete extension_list->next(); |
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| 181 | delete extension_list; |
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| 182 | } |
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| 183 | } |
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| 184 | |
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| 185 | |
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| 186 | int ALI_PT::find_family(ALI_SEQUENCE *sequence, int find_type) |
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| 187 | { |
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| 188 | unsigned long number; |
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| 189 | int matches, max_matches; |
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| 190 | char *seq_name; |
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| 191 | T_PT_FAMILYLIST f_list; |
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| 192 | ali_pt_member *pt_member; |
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| 193 | char *species; |
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| 194 | |
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| 195 | bytestring bs; |
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| 196 | bs.data = sequence->string(); |
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| 197 | bs.size = strlen(bs.data)+1; |
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| 198 | |
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| 199 | family_list = new ALI_TLIST<ali_pt_member *>; |
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| 200 | extension_list = new ALI_TLIST<ali_pt_member *>; |
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| 201 | if (family_list == 0 || extension_list == 0) |
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| 202 | ali_fatal_error("Out of memory"); |
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| 203 | |
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| 204 | if (mode == ServerMode) { |
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| 205 | /* Start find_family() at the PT_SERVER |
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| 206 | * |
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| 207 | * Here we have to make a loop, until the match count of the |
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| 208 | * first member is big enought |
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| 209 | */ |
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| 210 | |
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| 211 | T_PT_FAMILYFINDER ffinder; |
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| 212 | if (aisc_create(link, PT_LOCS, locs, |
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| 213 | LOCS_FFINDER, PT_FAMILYFINDER, ffinder, |
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| 214 | FAMILYFINDER_FIND_TYPE, find_type, |
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| 215 | FAMILYFINDER_FIND_FAMILY, &bs, |
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| 216 | NULL)) |
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| 217 | { |
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| 218 | ali_message ("Communication Error (2)"); |
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| 219 | return -1; |
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| 220 | } |
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| 221 | |
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| 222 | // Read family list |
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| 223 | aisc_get(link, PT_FAMILYFINDER, ffinder, |
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| 224 | FAMILYFINDER_FAMILY_LIST, f_list.as_result_param(), |
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| 225 | NULL); |
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| 226 | if (!f_list.exists()) |
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| 227 | ali_error("Family not found in PT Server"); |
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| 228 | |
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| 229 | aisc_get(link, PT_FAMILYLIST, f_list, |
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| 230 | FAMILYLIST_NAME, &seq_name, |
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| 231 | FAMILYLIST_MATCHES, &matches, |
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| 232 | FAMILYLIST_NEXT, f_list.as_result_param(), |
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| 233 | NULL); |
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| 234 | |
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| 235 | while (strcmp(seq_name, sequence->name()) == 0) { |
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| 236 | free(seq_name); |
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| 237 | if (!f_list.exists()) |
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| 238 | ali_error("Family too small in PT Server"); |
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| 239 | aisc_get(link, PT_FAMILYLIST, f_list, |
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| 240 | FAMILYLIST_NAME, &seq_name, |
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| 241 | FAMILYLIST_MATCHES, &matches, |
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| 242 | FAMILYLIST_NEXT, f_list.as_result_param(), |
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| 243 | NULL); |
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| 244 | } |
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| 245 | // found the first element |
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| 246 | |
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| 247 | // make the family list |
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| 248 | max_matches = matches; |
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| 249 | number = 0; |
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| 250 | do { |
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| 251 | pt_member = new ali_pt_member(seq_name, matches); |
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| 252 | family_list->append_end(pt_member); |
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| 253 | number++; |
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| 254 | do { |
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| 255 | if (!f_list.exists()) |
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| 256 | ali_error("Family too small in PT Server"); |
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| 257 | aisc_get(link, PT_FAMILYLIST, f_list, |
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| 258 | FAMILYLIST_NAME, &seq_name, |
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| 259 | FAMILYLIST_MATCHES, &matches, |
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| 260 | FAMILYLIST_NEXT, f_list.as_result_param(), |
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| 261 | NULL); |
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| 262 | if (strcmp(seq_name, sequence->name()) == 0) |
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| 263 | free(seq_name); |
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| 264 | } while (strcmp(seq_name, sequence->name()) == 0); |
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| 265 | } while (number < fam_list_max && |
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| 266 | (float) matches / (float) max_matches > percent_min); |
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| 267 | |
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| 268 | // make the extension list |
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| 269 | number = 0; |
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| 270 | while (number < ext_list_max) { |
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| 271 | pt_member = new ali_pt_member(seq_name, matches); |
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| 272 | extension_list->append_end(pt_member); |
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| 273 | number++; |
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| 274 | do { |
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| 275 | if (!f_list.exists()) |
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| 276 | ali_error("Family too small in PT Server"); |
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| 277 | aisc_get(link, PT_FAMILYLIST, f_list, |
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| 278 | FAMILYLIST_NAME, &seq_name, |
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| 279 | FAMILYLIST_MATCHES, &matches, |
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| 280 | FAMILYLIST_NEXT, f_list.as_result_param(), |
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| 281 | NULL); |
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| 282 | if (strcmp(seq_name, sequence->name()) == 0) |
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| 283 | free(seq_name); |
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| 284 | } while (strcmp(seq_name, sequence->name()) == 0); |
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| 285 | } |
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| 286 | } |
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| 287 | else { |
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| 288 | number = 0; |
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| 289 | while ((species = get_family_member(specified_family, number)) != 0) { |
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| 290 | pt_member = new ali_pt_member(species, matches_min); |
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| 291 | if (pt_member == 0) |
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| 292 | ali_fatal_error("Out of memory"); |
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| 293 | family_list->append_end(pt_member); |
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| 294 | number++; |
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| 295 | } |
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| 296 | |
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| 297 | if (number == 0) |
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| 298 | ali_fatal_error("Specified family too small"); |
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| 299 | |
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| 300 | number = 0; |
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| 301 | while ((species = get_extension_member(specified_family, number)) != 0) { |
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| 302 | pt_member = new ali_pt_member(species, |
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| 303 | (int) (matches_min * percent_min) - 1); |
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| 304 | if (pt_member == 0) |
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| 305 | ali_fatal_error("Out of memory"); |
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| 306 | extension_list->append_end(pt_member); |
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| 307 | number++; |
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| 308 | } |
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| 309 | } |
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| 310 | |
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| 311 | free(bs.data); |
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| 312 | return 0; |
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| 313 | } |
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| 314 | |
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| 315 | |
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| 316 | ALI_TLIST<ali_pt_member *> *ALI_PT::get_family_list() |
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| 317 | { |
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| 318 | ALI_TLIST<ali_pt_member *> *ret; |
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| 319 | |
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| 320 | ret = family_list; |
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| 321 | family_list = 0; |
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| 322 | |
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| 323 | return ret; |
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| 324 | } |
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| 325 | |
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| 326 | |
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| 327 | ALI_TLIST<ali_pt_member *> *ALI_PT::get_extension_list() |
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| 328 | { |
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| 329 | ALI_TLIST<ali_pt_member *> *ret; |
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| 330 | |
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| 331 | ret = extension_list; |
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| 332 | extension_list = 0; |
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| 333 | |
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| 334 | return ret; |
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| 335 | } |
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| 336 | |
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