source: tags/ms_r16q4/arb_CHANGES.txt

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1ARB change log
2
3Major changes for next release:
4
5 - ARB PARSIMONY
6   * topology optimization
7     - now (by default) strictly restricted to marked/visible parts of the tree (#640)
8     - restriction now customizable (marked/all; visible/all)
9     - tree costs for protein-data were not independent from root-position (as expected by model; #633).
10       Caused infinite running optimization under some circumstances.
11     - optimize-modes now strictly restrict to clicked subtrees. single/repeated optimization possible.
12     - KL-optimizer
13       * static path reduction slightly changed meaning. changed default settings.
14       * removed randomness (was just covering some bugs)
15       * improved general optimization speed
16   * branchlength calculation
17     - "forgot" to recalculate lengths under some conditions. fixed.
18     - is now independent of tree-root position (#641)
19   * adding species
20     - 'add partial species' failed if two partial species had NO overlap (#609). fixed.
21     - in 'add species + NNI' local optimization quality depended on insert position. fixed.
22     - insertion of multiple species is now done independently (=unordered)
23     - performance improved (esp. for many added species/big trees)
24   * generally improved combine performance (using SSE)
25   * generally reduced the number of performed combines (skipping many useless)
26   * added function to randomize (parts of) the tree
27   * warns about insufficient sequence data (e.g. as result of too restrictive filtering; #631)
28   * fixed 'RESTORE' (crashed after deleting species from tree; #528)
29   * corrected handling of dots ('.') while combining anchestor sequences
30   * fixed a bunch of internal bugs (#620, #627, ...)
31   * added species-info mode
32 - DNA realigner
33   * several unjustified failures will no longer happen (fixes #419 and most likely #145)
34     - correctly re-syncs after 'X' (if possible at all)
35     - no longer fails for 'B' and 'Z'
36     - accepts 3 or more consecutive IUPAC codes in DNA
37   * added option to cut-off DNA sequence (was done at end of sequence by old version. fixed)
38   * fixed several minor bugs
39 - ARB probeSpec: visualisation of probe set specificity (thanks to Paavo Jumppanen, CSIRO)
40 - species selections (editor configurations):
41   * visualisation of multiple selections in standard tree view (#658; example in database demo.arb)
42   * order can be changed; each configuration has a comment; import stores configuration (#607)
43 - Tree shading (#443)
44   * according to values stored in database
45   * according to given topology (useful when comparing topologies)
46 - support for extra database compression (using gzip, bzip2, xz); databases cannot be opened by arb versions before 6.1.x
47 - ARB_EDIT4:
48   * display selected database fields as flags (allowing to toggle their value; #261).
49     Example use: easily mark sequence as "curated" after manually checking its alignment.
50   * allow to load missing SAIs
51   * "view differences" to a reference sequence:
52      - customizable:
53        * char used for "equality" (i.e. what is displayed where a sequence is equal to selected sequence)
54        * case-sensitivity
55        * ignore different gap-types
56      - equal data also gets hidden in consensus
57      - refresh differences of all displayed sequences, when data of selected sequences changes
58      - change reference sequence using CTRL-R or automatically let it follow the cursor
59      - added hotkey to toggle mode: CTRL-D
60      - fixed minor bugs
61   * consensus calculation in ARB_EDIT4 and calculation of CONSENSUS SAI
62     - now both calculations are strictly consistent:
63       * gaps are now ignored while deciding whether to simplify using IUPAC ambiguity codes
64       * IUPAC ambiguity codes encountered in sequence data are now counted proportionally (=> fewer 'N's occur in consensus)
65     - added sliders to consensus definition windows
66     - user defined consensus settings exchangable between both consensus setups
67     - fixed and updated documentation
68   * added species-info mode + database save
69 - SAI: MAX_FREQUENCY
70   * considers IUPAC ambiguity codes proportionally
71   * amino acids: if MAX_FREQUENCY is below 10% SAI now shows '1' (prev. it did show '0', i.e. 100%)
72 - expand zombies in tree (unfold groups)
73 - compare taxonomy (and mark differences; #651)
74 - external (command line) aligners:
75   * fixed incorrect handling of 'T' vs 'U': now all aligned sequences will contain the correct base depending on alignment type
76   * preserve gap-type ('-' vs '.') and upper-/lower-case of original alignment
77   * no longer ask what to do with aligned sequence, just overwrite it
78     - only warn about real sequence changes (so please do NOT ignore from now on!)
79 - config-managers:
80   * possibility to restore factory defaults
81   * added comment field for configurations
82   * added them throughout arb (#647)
83 - added slide controls throughout arb (#656)
84 - tree (display) options:
85   * fine grained scaling
86   * improved auto-jump
87   * add threshold for visible support values
88   * group display (shading, customizable counters, triangle clades, optimized name+bootstrap display position)
89   * diagonal branch style
90   * parent branch position
91   * all options are now also supported by ARB_PARSIMONY
92 - synchronized tree scrolling (#683)
93 - colorsets were invalidated by generating new IDs (#660). fixed.
94 - added alternate RAxML (DNA only; version 8.2.8)
95   - multicore support (automatically activates recommended number of threads)
96   - evaluation, optimization and extension of existing trees with RAxML
97 - updated integrated documentation
98 - fix performance of "format sequences" (broken in arb-6.0.x series; #702)
99
100Minor changes
101 - corrected EMBL export filter (numbers at seq.data)
102 - NDS optionally uses only visible definitions
103
104Fixes for arb-6.0.5 (4 May 2016):
105
106 - fixes for ubuntu 16.04 build
107
108Fixes for arb-6.0.4 (2 May 2016):
109
110 - fixes for OSX build (SIP, accepted compilers)
111
112Fixes for arb-6.0.3 (19 Nov 2015):
113
114 - fixes permission problems when multiple users share databases or ptservers (thx to Alan McCulloch)
115
116Fixes for arb-6.0.2 (8 Aug 2014):
117
118 - compile issues on Snow Leopard (OSX 10.6)
119 - merge Debian security fix for CVE-2008-5378
120 - small changes to build system for Debian
121 - add desktop integration files
122
123Fixes for arb-6.0.1 (22 Jul 2014):
124
125 - arb_parsimony
126   - skip unwanted automatic branchlength recalculations (e.g. by unfolding a group)
127   - corrected branchlength calculation for "Add marked partial species"
128   - dots were treated as gaps for protein sequences (now treated as 'X'; analog to DNA treating gaps as 'N'). thx to Yan Shi for detecting that problem!
129 - print
130   - preview failed (showed empty postscript file)
131   - print to file now always saves in user home
132 - raxml (import tree with bootstrap values)
133
134Major changes for arb-6.0 (4 Jun 2014):
135
136 - merge databases allows to
137   - merge from an existing database into the database loaded in ARB_NT
138   - merge to existing databases from the database loaded in ARB_NT
139 - ARB can now
140   - be restarted with another database and
141   - a second instance of ARB can be opened
142 - ARB_DIST
143   - Detect clusters of species with similar sequences (OTUs)
144   - allow automatic recalculation of matrix and/or tree whenever some parameter or
145     data changes (only makes sense for smaller species sets)
146   - extract distance matrix from tree
147 - Rewrote chimera check. Allows filtering
148 - added RNACMA (computes clusters of correlated positions)
149 - PT-Server
150   - changed behavior
151     - no longer report less hits for a part of a probe than for the probe itself (occurred at 3'-end of alignment)
152     - reports previously missing hits in joined genes
153     - reports more hits at 3'-end of alignment (when using mismatches the PT-server now reports possible
154       matches that go beyond the end of the sequence)
155     - dots in the middle of the alignment act like the sequence ends there
156     - minimum probe length reduced to 2 (was 6)
157     - allow up to 50% of probe to mismatch
158   - performance
159     - optimized memory-estimation (will build in fewer passes)
160     - uses any number of passes (not only 1, 5, 25, ...)
161     - allows to define used memory by setting environment variable ARB_MEMORY
162     - reduced memory needed to build/run ptserver (approx. 50%)
163     - reduced size of indexfile (.pt) to ~50%
164     - fast startup of existing ptservers
165   - probe design
166     - faster in many cases
167     - allow to design probes of length 8 (previously 10)
168     - allow to design probes with different lengths (specifying min/max length)
169     - fixed number of outgroup hits reported when decreasing temperature
170       (now each outgroup member only occurs once)
171     - show possible reasons why no probes could be designed
172   - probe match (allow any number of mismatches)
173   - next relative search
174     - can be restricted to column ranges (needs a PT-Server calculated from aligned sequences)
175     - corrected and improved scaling of relative scores
176     - more accurate scores (due to fixes in PT-Server; see below)
177     - faster in many cases
178   - show errors from ptserver build in ARB
179 - fast-aligner
180   - searches next-relatives based on selected column-block
181   - align multiple column-blocks based on SAI
182 - Rewrote alignment adaption during merge
183 - Insert/delete columns using a SAI to define affected columns
184 - ARB_EDIT4
185   - improved support for using multiple edit-windows
186   - smoother refreshes
187   - tweaked ORF display
188 - tree importer/exporter
189   - ARBs extended newick format (with bootstrap values) handled more restrictive now
190   - fixed several bugs; improved errors/warnings
191 - consensus trees
192   - calculate from multiple existing trees (also allows to merge not completely overlapping trees)
193   - fixed NJ-bootstrapping (no longer drops species)
194 - tree display
195   - Show brackets on open groups (dendrogram tree only)
196   - rewrote IRS (folded) display
197   - fixed tree key-bindings (mark, fold, ...)
198   - improved several tree-commands (move, rotate, spread, length, width)
199 - added a branch analysis tool
200   - groups several functions previously available via menuitems (e.g. mark long branches, etc.)
201   - added leaf-distance analysis
202 - other tree functionality
203   - treelist sortable now
204   - new beautify-tree modes (radial tree / according to other tree)
205   - function to remove marked/zombies from ALL trees
206   - create multifurcations (by branchlength/bootstrap limit)
207   - toggle 100% bootstrap values
208 - tweaked printing (interface, overlapping)
209 - if YOU edit a helpfile it will be automatically packed into an archive ready to be sent to ARB developers
210 - probe design:
211   - added LOAD to result window
212 - automation
213   - macro recording works in ARB client applications (ARB_EDIT4, ARB_PARS, ARB_MERGE, ..)
214   - arb_ntree can execute macro from command line
215   - added "Never ask again" to modal question boxes (for better compatibility with macros)
216   - a macro can be called for all marked species (once for each)
217   - macros can be nested (i.e. can call other macros)
218 - support for user-specific customization:
219   - of GDE menus (in ~/.arb_prop/gde)
220   - of import/export filters (in ~/.arb_prop/filter)
221 - ACI (some new commands, bugfixes)
222 - updated/added external tools:
223   - added FastTree (version 2.1.7)
224   - added MAFFT (version 7.055)
225   - added MrBayes (version 3.2.1)
226   - added MUSCLE (version 3.8.31)
227   - added PHYML (2013/07/08; also kept old version 2.4.5)
228   - added PROBCONS (version 1.12)
229   - updated RAxML (version 7.7.2)
230 - load/save for window specific settings (e.g. allows to share parts of configuration with other users)
231 - Support for mouse-wheel
232 - many unlisted bugfixes
233 - many internal refactorings
234
235
236Fixes for arb_5.5 (15 Nov 2012):
237
238 * arb_5.4 was broken (several external tools missing)
239
240
241Fixes for arb_5.4 (14 Nov 2012):
242
243 * make it obvious when probe matches are truncated. Truncate all hits beyond 1 million (was 100000)
244 * fixed realigner (better interaction with fields 'transl_table' and 'codon_start'; improved error handling)
245 * fixed several compilation issues (OSX; recent distro releases)
246
247
248Fixes for arb_5.3 (10 Nov 2011):
249
250 - bugfixes
251   - fixed wrong absolute/ecoli position reported for some designed probes
252   - decompression error handling (pt-server build issues)
253   - fixed 'codon_start' generated with wrong type
254   - fixed a buffer overflow in ACI
255   - report failures to write to /tmp
256 - changes
257   - markSpecies.pl:
258     mark by accession number
259     partial/ambiguous matches
260 - internal fixes
261   - compilation fixes for OSX
262   - some patches for debian version (removed refs to xview, textedit, removed molphy(protml))
263   - removed obsolete dependency from libXp
264
265
266Fixes for arb_5.2 (5 Sep 2010):
267
268 - bugfixes
269   - quicksave did silently do nothing (especially not save anything) if an error occurred
270   - ARB_EDIT4: crashed when using config with MANY unknown species
271   - ARB_SECEDIT: crashed when trying to paint strand w/o any base
272   - ARB_NTREE/ARB_PARS: crashed when clicking on inner tree node w/o groupinfo
273 - changes
274   - ARB uses xdg-open to display web-pages
275 - internal fixes
276   - karmic koala (gcc 4.4.1)
277   - installation script
278   - arb build process uses xsltproc instead of sablotron
279
280
281Fixes for arb_5.1 (1 Oct 2009):
282
283 - fixed a bug in 'Create species from consensus' (created sequence was corrupted)
284 - fixed 2 bugs in optimize DB (alignment w/o data, missing transaction)
285 - updated installation instructions, fixed install script, added OSX instruction (thx to Matt Cottrell)
286 - fixed broken demo.arb
287
288
289Major changes for arb_5.00 (4 Sep 2009):
290
291 - ARB 64bit version
292 - new genome importer
293 - search for next relatives improved (normal search and fast-aligner)
294   - new parameters to precise search
295   - improved speed
296   - partial sequence reach normal scores
297 - search&query
298   - supports regular expressions and ACI
299   - track hit information
300   - result sorting
301 - Nameservers with add.field have to be started with default value
302   You need to correct parameter -f in lib/arb_tcp.dat (according to lib/arb_tcp_org.dat)
303 - multiple PT-servers may be used in parallel
304 - fixed multiprobe
305 - type-conversion for DB fields
306 - SILVA compatible import filters
307 - Newick tree export:
308   - optionally save in human-readable format (big)
309   - closer to newick standard format (quoting style, comment, special chars in data)
310 - Upgraded RAxML to 7.0.3 (many features now usable from ARB interface)
311 - Fixed sequence quality calculation
312 - Secondary structures for proteins (DSSP)
313 - Distance matrix (arb_dist): mark by distance to selected
314 - ARB core
315   - many bugfixes and improvements to reliability
316   - faster sorting (general speedup)
317   - improved sequence compression (avoid worse trees, better ratio)
318   - improved handling of temporary files (permission/removal)
319   - prints backtraces in userland
320   - regular expression are POSIX standard now
321 - macro record/playback
322   - fixed several bugs
323   - you need to re-record your old macros!
324 - GUI:
325   - disabled auto-focus, you need to click now
326   - auto-raise windows on access
327 - Minor things:
328   - Ubuntu: packet installation for ARB
329   - Fixed novice/expert mode
330   - Mark deep/degenerated branches
331   - Increased NDS entries
332 - up-to-date Mac port (thx to Matt Cottrell)
333
334Major changes in ARB 07.12.07org (7 Dec 2007):
335
336 - rewrote secondary structure editor
337 - Sequence quality check
338 - Nameserver may use one field additional to 'acc' (useful to keep multiple species with same acc)
339 - tweaked base frequency filter generation
340 - Normal export (not using readseq) improved:
341   - supports filters and gap removal
342   - optimized for big amount of data
343   - reworked export filters
344 - Display translation with different ORFs in EDIT4
345 - ARB exports in FIG 3.2 format (optionally in colors). Thanks to Elmar Pruesse.
346 - added PHYML 2.4.5 (thanks to Stephane Guidon for the permission to distribute that great tool)
347 - more compact display in EDIT4
348 - capable to use iso10646 fonts
349 - supports various gcc versions (2.95.3 - 4.1.1)
350 - fixed a bug in DB optimization (occurred when fields had bigger protection than current)
351 - Bootstrap circles may be displayed as ellipses; upper size limit configurable; uses
352   different color for size-limited circles; fixed xfig-export-bug
353 - Allows Branchlength <-> Bootstrap value transfer (lossy!)
354 - fixed several scaling bugs in "folded tree"-mode
355 - improved import-filter error-messages
356 - NDS-display of groups (e.g. in tree) is now handled by ACI-command 'taxonomy'. This gives
357   several new possibilities:
358   - export taxonomy via 'Export NDS list'
359   - display taxonomy in Editor etc.
360   - display of cascaded taxonomies
361   - display taxonomy of tree_1 in tree_2
362   - allows to write taxonomy into database field of species
363   - compare taxonomies of two trees
364   - ...
365 - ACI:
366   - many new ACI commands
367   - unified handling of binary ACI-operators
368   - tracing of ACI actions for debugging purpose
369 - ARB Neighbour joining:
370   - bootstrap limit configurable
371   - bugfix: when aborting bootstrap calculation, sometimes no tree was generated
372 - EDIT4:
373   - added unalign right (block-op)
374   - added 'Save loaded properties'
375 - GENE MAP:
376   - multiple views possible at the same time
377   - origin now at "12 o'clock"
378   - implemented 'jump to gene'
379 - tweaked file selection
380 - Enhanced Search Depth for Probe Match --> max 20 MM
381 - CLUSTALW:
382   - separated menus for fast and slow alignment
383   - most parameters accessible from inside ARB now
384 - upgraded to PHYLIP 3.6 (adds PROML)
385 - external programs may be called parallel (e.g. several treeing programs)
386 - fixed bugs in protml and integration of protml
387 - rewrote ASCII database import
388 - arb_repair for databases of any size (script for database repair)
389 - fixed bug in data compression
390 - increased internal cache size (alignments up to 400.000bp possible w/o performance collapse)
391 - ARBparsimony: increase hardcoded species limit (50.000 -> 250.000)
392 - GDE menus cleanup
393 - translation/re-alignment tweaked
394 - unalign right (EDIT4)
395 - visualization of SAIs in Probe Match Results
396 - changed formatting of probe match results; increase # of allowed matches to 100.000;
397   warn if results are truncated
398 - PT server for genes
399 - Probe design performance optimized
400 - fixed NEXUS export format
401 - exports group names into Newick format
402 - import XML tree files
403 - help for external tools now properly shown inside ARB
404
405Major changes in Beta 2003_08_22 (22 Aug 2003):
406
407 - automatic formatting of alignments
408 - SECEDIT may use EDIT4 colors
409 - fixed bootstrapping (DNAPARS, PROTPARS, PROTML(experimental!))
410 - updated clustalw to version 1.83
411 - Restore window sizes for ALL windows (too small sizes are ignored)
412 - new algorithm to add partial sequences to an existing tree
413 - PROT-parsimony was completely redesigned and works now most similar to DNA/RNA-parsimony
414 - Top area of ARB_NTREE may be reduced to maximize display area
415 - All arb menus may be detached (click dashed line at top of menu)
416 - visualization of SAIs (as background color behind Sequences)
417 - ARB_EDIT4 may save/use alignment-specific and alignment-type-specific properties
418 - PT-server occupies more memory => does less passes; more diagnostic output
419 - small changes to status window (unhide behavior/time estimation)
420 - menus and menu-hotkeys reorganized
421 - colored buttons in color config windows
422 - alignment concatenation (e.g. several different genes)
423 - merging data of similar species (according selected database field)
424 - keyboard commands for ARB_NTREE (mark/unmark/invert, collapse/expand)
425 - expanded sellists
426 - save/load fixed for multi probes
427 - Binary SAIs are editable in ARB_EDIT4
428 - Information windows are detachable (allows to have multiple windows showing different items)
429 - Scanning for hidden/unknown database fields improved and separated;
430   possibility to remove unused fields.
431 - new tabbed format in 'Export NDS' and 'Export matrix' (useful for star-calc/excel/etc.)
432 - updated fastDNAml to 1.2.2
433 - added AxML (accelerated fastDNAml 1.2.2)
434 - Field transfer definitions for exporting gene-species
435 - File Selection: - recursive search available
436 - The ARB_NTREE macro recording/execution has been fixed
437 - Colorize species (see demo.arb)
438 - Fixed missing-character-bug in Xfig, Print and Edit4-Info-Display
439 - 'IslandHopper' -- a new integrated aligner (beta)
440 - Many improvements and bugfixes to secondary structure editor:
441   - highlighting of search (i.e for probes) like in EDIT4
442   - interactive constraint editing (stretch/compress)
443   - probe info
444   - editing secondary structure in XFIG now possible
445   - visualization of SAIs
446 - import reads Unix, DOS, and MAC linefeeds
447 - NTREE/SAI/Etc/GnuPlot: calls gnuplot directly; more plotting features; basic help
448 - tree and sequence export to XML ( DTDs are provided in ./lib/dtd )
449   (reloading of these XML files is planned for the future)
450 - fixed problems with phylip-tree import/export (bootstrap values,comments,...)
451 - search in all database fields possible ('[all fields]')
452 - up to 10 quicksaves are kept
453 - new ACI functions: upper, lower, caps, eval
454 - variables for import filter programming
455 - extract gene-species: creates acc; extraction to existing alignments
456 - sequence of selected gene is mirrored in ARB_EDIT4/local_signature
457   (=> selected gene can be highlighted in primary editor)
458 - PCR primer-design for single genes
459 - when selecting a gene, the corresponding gene-species is selected (if found)
460 - save configuration for several windows (e.g. Search&Query, WWW, NDS, ...)
461 - file selection box in import window
462 - mark item with double click works in all search&query windows
463 - User masks: create new; 'edit enable' and 'marked' toggles (like in info window)
464 - Fixed command line help for all Arb-modules
465 - Fixed problem parsing fonts (should fix display problems with default fonts)
466 - Mark mode now works in list-view as well (ARB_NTREE)
467 - Fixed appearance of 'tiny little boxes' (everywhere)
468 - Redesign of ARB help:
469     - a HTML version is in $ARBHOME/lib/help_html
470     - a text version is in $ARBHOME/lib/help (like before, but now generated)
471
472Major changes in Beta 2001_11_07 (7 Nov 2001):
473
474 - design probes to maximum length of 60 nucleotides
475 - fastAligner1.03 bug fixed (chooses best match now in 'auto search' mode)
476 - import default changed to foreign data format, ali name '16s'
477 - printing of multi-page-trees works again
478 - implemented user defineable masks to access database fields
479 - fixed bugs in pt-server (lockup, unknown species just after building pt-server)
480 - improved performance during pt-server-build
481 - several programs coming along with ARB where updated (PHYLIP,...)
482 - reads EMBL genom files
483 - support for experiments (genom databases only)
484
485Major changes in Beta 2001_07_24 (24 Jul 2001):
486
487 - basic support for genoms (Gene Map, reads Genebank files)
488 - ported to libc6
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