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1 | #ifndef MSADist_h |
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2 | #define MSADist_h |
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3 | |
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4 | #include <math.h> |
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5 | |
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6 | double GetScoreDist(const MSA &msa, unsigned SeqIndex1, unsigned SeqIndex2); |
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7 | |
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8 | class MSADist |
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9 | { |
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10 | public: |
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11 | MSADist(DISTANCE Distance) |
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12 | { |
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13 | m_Distance = Distance; |
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14 | } |
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15 | |
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16 | double ComputeDist(const MSA &msa, unsigned uSeqIndex1, unsigned uSeqIndex2) |
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17 | { |
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18 | if (m_Distance == DISTANCE_ScoreDist) |
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19 | return GetScoreDist(msa, uSeqIndex1, uSeqIndex2); |
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20 | |
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21 | double dPctId = msa.GetPctIdentityPair(uSeqIndex1, uSeqIndex2); |
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22 | switch(m_Distance) |
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23 | { |
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24 | case DISTANCE_PctIdKimura: |
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25 | return KimuraDist(dPctId); |
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26 | case DISTANCE_PctIdLog: |
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27 | if (dPctId < 0.05) |
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28 | dPctId = 0.05; |
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29 | return -log(dPctId); |
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30 | } |
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31 | Quit("MSADist::ComputeDist, invalid DISTANCE_%u", m_Distance); |
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32 | return 0; |
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33 | } |
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34 | |
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35 | private: |
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36 | DISTANCE m_Distance; |
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37 | }; |
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38 | |
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39 | #endif // MSADist_h |
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