1 | |
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2 | #include "phylip.h" |
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3 | #include "disc.h" |
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4 | #include "wagner.h" |
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5 | |
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6 | /* version 3.6. (c) Copyright 1993-2002 by the University of Washington. |
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7 | Written by Joseph Felsenstein, Akiko Fuseki, Sean Lamont, and Andrew Keeffe. |
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8 | Permission is granted to copy and use this program provided no fee is |
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9 | charged for it and provided that this copyright notice is not removed. */ |
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10 | |
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11 | #define maxtrees 100 /* maximum number of tied trees stored */ |
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12 | |
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13 | typedef long *placeptr; |
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14 | |
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15 | #ifndef OLDC |
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16 | /* function prototypes */ |
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17 | void getoptions(void); |
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18 | void allocrest(void); |
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19 | void doinit(void); |
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20 | void inputoptions(void); |
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21 | void doinput(void); |
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22 | void evaluate(node2 *); |
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23 | void reroot(node2 *); |
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24 | void savetraverse(node2 *); |
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25 | void savetree(void); |
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26 | void mix_addtree(long *pos); |
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27 | |
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28 | void mix_findtree(boolean *, long *, long, long *, long **); |
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29 | void tryadd(node2 *, node2 **, node2 **); |
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30 | void addpreorder(node2 *, node2 *, node2 *); |
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31 | void tryrearr(node2 *, node2 **, boolean *); |
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32 | void repreorder(node2 *, node2 **, boolean *); |
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33 | void rearrange(node2 **r); |
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34 | void mix_addelement(node2 **, long *, long *, boolean *); |
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35 | void mix_treeread(void); |
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36 | void describe(void); |
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37 | void maketree(void); |
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38 | void reallocchars(void); |
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39 | /* function prototypes */ |
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40 | #endif |
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41 | |
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42 | |
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43 | |
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44 | Char infilename[FNMLNGTH], outfilename[FNMLNGTH], intreename[FNMLNGTH], outtreename[FNMLNGTH], weightfilename[FNMLNGTH], ancfilename[FNMLNGTH], mixfilename[FNMLNGTH]; |
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45 | node2 *root; |
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46 | long outgrno, msets, ith, njumble, jumb; |
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47 | /* outgrno indicates outgroup */ |
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48 | long inseed, inseed0; |
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49 | boolean jumble, usertree, weights, thresh, ancvar, questions, allsokal, |
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50 | allwagner, mixture, trout, noroot, outgropt, didreroot, |
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51 | progress, treeprint, stepbox, ancseq, mulsets, firstset, |
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52 | justwts; |
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53 | boolean *ancone, *anczero, *ancone0, *anczero0; |
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54 | pointptr2 treenode; /* pointers to all nodes in tree */ |
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55 | double threshold; |
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56 | double *threshwt; |
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57 | bitptr wagner, wagner0; |
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58 | longer seed; |
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59 | long *enterorder; |
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60 | double **fsteps; |
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61 | char *guess; |
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62 | long **bestrees; |
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63 | steptr numsteps, numsone, numszero; |
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64 | gbit *garbage; |
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65 | char global_ch; |
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66 | char *progname; |
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67 | |
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68 | /* Local variables for maketree: */ |
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69 | long minwhich; |
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70 | double like, bestyet, bestlike, bstlike2, minsteps; |
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71 | boolean lastrearr,full; |
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72 | double nsteps[maxuser]; |
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73 | node2 *there; |
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74 | long fullset; |
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75 | bitptr steps, zeroanc, oneanc, fulzeroanc, empzeroanc; |
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76 | long *place, col; |
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77 | |
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78 | void getoptions() |
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79 | { |
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80 | /* interactively set options */ |
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81 | long loopcount, loopcount2; |
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82 | Char ch, ch2; |
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83 | |
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84 | fprintf(outfile, "\nMixed parsimony algorithm, version %s\n\n",VERSION); |
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85 | putchar('\n'); |
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86 | jumble = false; |
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87 | njumble = 1; |
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88 | outgrno = 1; |
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89 | outgropt = false; |
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90 | thresh = false; |
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91 | threshold = spp; |
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92 | trout = true; |
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93 | usertree = false; |
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94 | weights = false; |
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95 | justwts = false; |
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96 | ancvar = false; |
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97 | allsokal = false; |
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98 | allwagner = true; |
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99 | mixture = false; |
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100 | printdata = false; |
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101 | progress = true; |
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102 | treeprint = true; |
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103 | stepbox = false; ancseq = false; |
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104 | loopcount = 0; |
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105 | for (;;) { |
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106 | cleerhome(); |
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107 | printf("\nMixed parsimony algorithm, version %s\n\n",VERSION); |
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108 | printf("Settings for this run:\n"); |
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109 | printf(" U Search for best tree? %s\n", |
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110 | (usertree ? "No, use user trees in input file" : "Yes")); |
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111 | printf(" X Use Mixed method? %s\n", |
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112 | (mixture ? "Yes" : "No")); |
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113 | printf(" P Parsimony method?"); |
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114 | if (!mixture) { |
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115 | printf(" %s\n",(allwagner ? "Wagner" : "Camin-Sokal")); |
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116 | } else |
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117 | printf(" (methods in mixture)\n"); |
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118 | if (!usertree) { |
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119 | printf(" J Randomize input order of species?"); |
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120 | if (jumble) |
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121 | printf(" Yes (seed =%8ld,%3ld times)\n", inseed0, njumble); |
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122 | else |
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123 | printf(" No. Use input order\n"); |
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124 | } |
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125 | printf(" O Outgroup root?"); |
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126 | if (outgropt) |
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127 | printf(" Yes, at species number%3ld\n", outgrno); |
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128 | else |
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129 | printf(" No, use as outgroup species%3ld\n", outgrno); |
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130 | printf(" T Use Threshold parsimony?"); |
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131 | if (thresh) |
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132 | printf(" Yes, count steps up to%4.1f per char.\n", threshold); |
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133 | else |
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134 | printf(" No, use ordinary parsimony\n"); |
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135 | printf(" A Use ancestral states in input file? %s\n", |
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136 | (ancvar ? "Yes" : "No")); |
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137 | printf(" W Sites weighted? %s\n", |
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138 | (weights ? "Yes" : "No")); |
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139 | printf(" M Analyze multiple data sets?"); |
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140 | if (mulsets) |
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141 | printf(" Yes, %2ld %s\n", msets, |
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142 | (justwts ? "sets of weights" : "data sets")); |
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143 | else |
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144 | printf(" No\n"); |
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145 | printf(" 0 Terminal type (IBM PC, ANSI, none)? %s\n", |
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146 | (ibmpc ? "IBM PC" : ansi ? "ANSI" : "(none)")); |
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147 | printf(" 1 Print out the data at start of run %s\n", |
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148 | (printdata ? "Yes" : "No")); |
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149 | printf(" 2 Print indications of progress of run %s\n", |
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150 | (progress ? "Yes" : "No")); |
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151 | printf(" 3 Print out tree %s\n", |
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152 | (treeprint ? "Yes" : "No")); |
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153 | printf(" 4 Print out steps in each character %s\n", |
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154 | (stepbox ? "Yes" : "No")); |
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155 | printf(" 5 Print states at all nodes of tree %s\n", |
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156 | (ancseq ? "Yes" : "No")); |
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157 | printf(" 6 Write out trees onto tree file? %s\n", |
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158 | (trout ? "Yes" : "No")); |
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159 | if(weights && justwts){ |
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160 | printf( |
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161 | "WARNING: W option and Multiple Weights options are both on. "); |
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162 | printf( |
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163 | "The W menu option is unnecessary and has no additional effect. \n"); |
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164 | } |
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165 | printf("\nAre these settings correct? "); |
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166 | printf("(type Y or the letter for one to change)\n"); |
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167 | #ifdef WIN32 |
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168 | phyFillScreenColor(); |
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169 | #endif |
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170 | scanf("%c%*[^\n]", &ch); |
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171 | getchar(); |
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172 | if (ch == '\n') |
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173 | ch = ' '; |
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174 | uppercase(&ch); |
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175 | if (ch == 'Y') |
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176 | break; |
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177 | if (strchr("WJOTUMPAX1234560",ch) != NULL){ |
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178 | switch (ch) { |
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179 | |
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180 | case 'W': |
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181 | weights = !weights; |
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182 | break; |
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183 | |
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184 | case 'U': |
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185 | usertree = !usertree; |
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186 | break; |
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187 | |
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188 | case 'X': |
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189 | mixture = !mixture; |
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190 | break; |
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191 | |
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192 | case 'P': |
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193 | allwagner = !allwagner; |
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194 | break; |
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195 | |
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196 | case 'A': |
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197 | ancvar = !ancvar; |
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198 | break; |
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199 | |
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200 | case 'J': |
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201 | jumble = !jumble; |
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202 | if (jumble) |
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203 | initjumble(&inseed, &inseed0, seed, &njumble); |
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204 | else njumble = 1; |
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205 | break; |
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206 | |
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207 | case 'O': |
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208 | outgropt = !outgropt; |
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209 | if (outgropt) |
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210 | initoutgroup(&outgrno, spp); |
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211 | break; |
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212 | |
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213 | case 'T': |
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214 | thresh = !thresh; |
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215 | if (thresh) |
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216 | initthreshold(&threshold); |
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217 | break; |
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218 | |
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219 | case 'M': |
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220 | mulsets = !mulsets; |
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221 | if (mulsets){ |
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222 | printf("Multiple data sets or multiple weights?"); |
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223 | loopcount2 = 0; |
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224 | do { |
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225 | printf(" (type D or W)\n"); |
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226 | #ifdef WIN32 |
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227 | phyFillScreenColor(); |
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228 | #endif |
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229 | scanf("%c%*[^\n]", &ch2); |
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230 | getchar(); |
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231 | if (ch2 == '\n') |
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232 | ch2 = ' '; |
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233 | uppercase(&ch2); |
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234 | countup(&loopcount2, 10); |
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235 | } while ((ch2 != 'W') && (ch2 != 'D')); |
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236 | justwts = (ch2 == 'W'); |
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237 | if (justwts) |
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238 | justweights(&msets); |
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239 | else |
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240 | initdatasets(&msets); |
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241 | if (!jumble) { |
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242 | jumble = true; |
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243 | initjumble(&inseed, &inseed0, seed, &njumble); |
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244 | } |
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245 | } |
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246 | break; |
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247 | |
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248 | case '0': |
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249 | initterminal(&ibmpc, &ansi); |
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250 | break; |
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251 | |
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252 | case '1': |
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253 | printdata = !printdata; |
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254 | break; |
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255 | |
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256 | case '2': |
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257 | progress = !progress; |
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258 | break; |
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259 | |
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260 | case '3': |
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261 | treeprint = !treeprint; |
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262 | break; |
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263 | |
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264 | case '4': |
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265 | stepbox = !stepbox; |
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266 | break; |
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267 | |
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268 | case '5': |
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269 | ancseq = !ancseq; |
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270 | break; |
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271 | |
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272 | case '6': |
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273 | trout = !trout; |
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274 | break; |
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275 | } |
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276 | } else |
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277 | printf("Not a possible option!\n"); |
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278 | countup(&loopcount, 100); |
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279 | } |
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280 | allsokal = (!allwagner && !mixture); |
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281 | } /* getoptions */ |
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282 | |
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283 | void reallocchars() |
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284 | { |
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285 | long i; |
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286 | |
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287 | if (usertree) { |
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288 | for (i = 0; i < maxuser; i++) { |
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289 | free (fsteps[i]); |
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290 | fsteps[i] = (double *)Malloc(chars*sizeof(double)); |
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291 | } |
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292 | } |
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293 | free(extras); |
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294 | free(weight); |
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295 | free(threshwt); |
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296 | free(numsteps); |
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297 | free(numszero); |
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298 | free(numsone); |
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299 | free(guess); |
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300 | free(ancone); |
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301 | free(anczero); |
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302 | free(ancone0); |
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303 | free(anczero0); |
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304 | |
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305 | extras = (steptr)Malloc(chars*sizeof(long)); |
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306 | weight = (steptr)Malloc(chars*sizeof(long)); |
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307 | threshwt = (double *)Malloc(chars*sizeof(double)); |
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308 | numsteps = (steptr)Malloc(chars*sizeof(long)); |
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309 | numszero = (steptr)Malloc(chars*sizeof(long)); |
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310 | numsone = (steptr)Malloc(chars*sizeof(long)); |
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311 | guess = (Char *)Malloc(chars*sizeof(Char)); |
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312 | ancone = (boolean *)Malloc(chars*sizeof(boolean)); |
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313 | anczero = (boolean *)Malloc(chars*sizeof(boolean)); |
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314 | ancone0 = (boolean *)Malloc(chars*sizeof(boolean)); |
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315 | anczero0 = (boolean *)Malloc(chars*sizeof(boolean)); |
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316 | } |
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317 | |
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318 | void allocrest() |
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319 | { |
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320 | long i; |
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321 | |
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322 | if (usertree) { |
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323 | fsteps = (double **)Malloc(maxuser*sizeof(double *)); |
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324 | for (i = 0; i < maxuser; i++) |
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325 | fsteps[i] = (double *)Malloc(chars*sizeof(double)); |
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326 | } |
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327 | bestrees = (long **)Malloc(maxtrees*sizeof(long *)); |
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328 | for (i = 1; i <= maxtrees; i++) |
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329 | bestrees[i - 1] = (long *)Malloc(spp*sizeof(long)); |
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330 | extras = (steptr)Malloc(chars*sizeof(long)); |
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331 | weight = (steptr)Malloc(chars*sizeof(long)); |
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332 | threshwt = (double *)Malloc(chars*sizeof(double)); |
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333 | numsteps = (steptr)Malloc(chars*sizeof(long)); |
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334 | numszero = (steptr)Malloc(chars*sizeof(long)); |
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335 | numsone = (steptr)Malloc(chars*sizeof(long)); |
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336 | guess = (Char *)Malloc(chars*sizeof(Char)); |
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337 | nayme = (naym *)Malloc(spp*sizeof(naym)); |
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338 | enterorder = (long *)Malloc(spp*sizeof(long)); |
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339 | ancone = (boolean *)Malloc(chars*sizeof(boolean)); |
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340 | anczero = (boolean *)Malloc(chars*sizeof(boolean)); |
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341 | ancone0 = (boolean *)Malloc(chars*sizeof(boolean)); |
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342 | anczero0 = (boolean *)Malloc(chars*sizeof(boolean)); |
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343 | wagner = (bitptr)Malloc(words*sizeof(long)); |
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344 | wagner0 = (bitptr)Malloc(words*sizeof(long)); |
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345 | place = (long *)Malloc(nonodes*sizeof(long)); |
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346 | steps = (bitptr)Malloc(words*sizeof(long)); |
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347 | zeroanc = (bitptr)Malloc(words*sizeof(long)); |
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348 | oneanc = (bitptr)Malloc(words*sizeof(long)); |
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349 | fulzeroanc = (bitptr)Malloc(words*sizeof(long)); |
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350 | empzeroanc = (bitptr)Malloc(words*sizeof(long)); |
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351 | } /* allocrest */ |
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352 | |
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353 | |
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354 | void doinit() |
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355 | { |
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356 | /* initializes variables */ |
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357 | |
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358 | inputnumbers(&spp, &chars, &nonodes, 1); |
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359 | words = chars / bits + 1; |
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360 | getoptions(); |
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361 | if (printdata) |
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362 | fprintf(outfile, "%ld species, %ld characters\n\n", spp, chars); |
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363 | alloctree2(&treenode); |
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364 | setuptree2(treenode); |
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365 | allocrest(); |
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366 | } /* doinit */ |
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367 | |
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368 | |
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369 | void inputoptions() |
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370 | { |
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371 | /* input the information on the options */ |
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372 | long i; |
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373 | |
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374 | if(justwts){ |
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375 | if(firstset){ |
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376 | scan_eoln(infile); |
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377 | if (ancvar) |
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378 | inputancestorsnew(anczero0, ancone0); |
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379 | if (mixture) |
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380 | inputmixturenew(wagner0); |
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381 | } |
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382 | for (i = 0; i < (chars); i++) |
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383 | weight[i] = 1; |
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384 | inputweights(chars, weight, &weights); |
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385 | for (i = 0; i < (words); i++) { |
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386 | if (mixture) |
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387 | wagner[i] = wagner0[i]; |
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388 | else if (allsokal) |
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389 | wagner[i] = 0; |
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390 | else |
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391 | wagner[i] = (1L << (bits + 1)) - (1L << 1); |
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392 | } |
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393 | } |
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394 | else { |
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395 | if (!firstset) { |
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396 | samenumsp(&chars, ith); |
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397 | reallocchars(); |
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398 | } |
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399 | scan_eoln(infile); |
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400 | for (i = 0; i < (chars); i++) |
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401 | weight[i] = 1; |
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402 | if (ancvar) |
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403 | inputancestorsnew(anczero0, ancone0); |
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404 | if (mixture) |
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405 | inputmixturenew(wagner0); |
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406 | if (weights) |
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407 | inputweights(chars, weight, &weights); |
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408 | for (i = 0; i < (words); i++) { |
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409 | if (mixture) |
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410 | wagner[i] = wagner0[i]; |
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411 | else if (allsokal) |
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412 | wagner[i] = 0; |
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413 | else |
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414 | wagner[i] = (1L << (bits + 1)) - (1L << 1); |
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415 | } |
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416 | } |
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417 | for (i = 0; i < (chars); i++) { |
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418 | if (!ancvar) { |
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419 | anczero[i] = true; |
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420 | ancone[i] = (((1L << (i % bits + 1)) & wagner[i / bits]) != 0); |
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421 | } else { |
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422 | anczero[i] = anczero0[i]; |
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423 | ancone[i] = ancone0[i]; |
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424 | } |
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425 | } |
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426 | noroot = true; |
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427 | questions = false; |
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428 | for (i = 0; i < (chars); i++) { |
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429 | if (weight[i] > 0) { |
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430 | noroot = (noroot && ancone[i] && anczero[i] && |
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431 | ((((1L << (i % bits + 1)) & wagner[i / bits]) != 0) |
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432 | || threshold <= 2.0)); |
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433 | } |
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434 | questions = (questions || (ancone[i] && anczero[i])); |
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435 | threshwt[i] = threshold * weight[i]; |
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436 | } |
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437 | } /* inputoptions */ |
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438 | |
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439 | |
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440 | void doinput() |
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441 | { |
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442 | /* reads the input data */ |
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443 | inputoptions(); |
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444 | if(!justwts || firstset) |
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445 | inputdata2(treenode); |
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446 | } /* doinput */ |
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447 | |
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448 | |
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449 | void evaluate(node2 *r) |
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450 | { |
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451 | /* Determines the number of steps needed for a tree. |
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452 | This is the minimum number needed to evolve chars on |
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453 | this tree */ |
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454 | long i, stepnum, smaller; |
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455 | double sum, term; |
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456 | |
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457 | sum = 0.0; |
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458 | for (i = 0; i < (chars); i++) { |
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459 | numszero[i] = 0; |
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460 | numsone[i] = 0; |
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461 | } |
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462 | full = true; |
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463 | for (i = 0; i < (words); i++) |
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464 | zeroanc[i] = fullset; |
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465 | postorder(r, fullset, full, wagner, zeroanc); |
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466 | cpostorder(r, full, zeroanc, numszero, numsone); |
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467 | count(r->fulstte1, zeroanc, numszero, numsone); |
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468 | for (i = 0; i < (words); i++) |
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469 | zeroanc[i] = 0; |
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470 | full = false; |
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471 | postorder(r, fullset, full, wagner, zeroanc); |
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472 | cpostorder(r, full, zeroanc, numszero, numsone); |
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473 | count(r->empstte0, zeroanc, numszero, numsone); |
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474 | for (i = 0; i < (chars); i++) { |
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475 | smaller = spp * weight[i]; |
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476 | numsteps[i] = smaller; |
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477 | if (anczero[i]) { |
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478 | numsteps[i] = numszero[i]; |
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479 | smaller = numszero[i]; |
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480 | } |
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481 | if (ancone[i] && numsone[i] < smaller) |
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482 | numsteps[i] = numsone[i]; |
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483 | stepnum = numsteps[i] + extras[i]; |
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484 | if (stepnum <= threshwt[i]) |
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485 | term = stepnum; |
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486 | else |
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487 | term = threshwt[i]; |
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488 | sum += term; |
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489 | if (usertree && which <= maxuser) |
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490 | fsteps[which - 1][i] = term; |
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491 | guess[i] = '?'; |
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492 | if (!ancone[i] || (anczero[i] && numszero[i] < numsone[i])) |
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493 | guess[i] = '0'; |
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494 | else if (!anczero[i] || (ancone[i] && numsone[i] < numszero[i])) |
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495 | guess[i] = '1'; |
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496 | } |
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497 | if (usertree && which <= maxuser) { |
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498 | nsteps[which - 1] = sum; |
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499 | if (which == 1) { |
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500 | minwhich = 1; |
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501 | minsteps = sum; |
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502 | } else if (sum < minsteps) { |
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503 | minwhich = which; |
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504 | minsteps = sum; |
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505 | } |
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506 | } |
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507 | like = -sum; |
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508 | } /* evaluate */ |
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509 | |
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510 | |
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511 | void reroot(node2 *outgroup) |
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512 | { |
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513 | /* reorients tree, putting outgroup in desired position. */ |
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514 | node2 *p, *q; |
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515 | |
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516 | if (outgroup->back->index == root->index) |
---|
517 | return; |
---|
518 | p = root->next; |
---|
519 | q = root->next->next; |
---|
520 | p->back->back = q->back; |
---|
521 | q->back->back = p->back; |
---|
522 | p->back = outgroup; |
---|
523 | q->back = outgroup->back; |
---|
524 | outgroup->back->back = q; |
---|
525 | outgroup->back = p; |
---|
526 | } /* reroot */ |
---|
527 | |
---|
528 | |
---|
529 | void savetraverse(node2 *p) |
---|
530 | { |
---|
531 | /* sets BOOLEANs that indicate which way is down */ |
---|
532 | p->bottom = true; |
---|
533 | if (p->tip) |
---|
534 | return; |
---|
535 | p->next->bottom = false; |
---|
536 | savetraverse(p->next->back); |
---|
537 | p->next->next->bottom = false; |
---|
538 | savetraverse(p->next->next->back); |
---|
539 | } /* savetraverse */ |
---|
540 | |
---|
541 | |
---|
542 | void savetree() |
---|
543 | { |
---|
544 | /* record in place where each species has to be |
---|
545 | added to reconstruct this tree */ |
---|
546 | long i, j; |
---|
547 | node2 *p; |
---|
548 | boolean done; |
---|
549 | |
---|
550 | if (noroot) |
---|
551 | reroot(treenode[outgrno - 1]); |
---|
552 | savetraverse(root); |
---|
553 | for (i = 0; i < (nonodes); i++) |
---|
554 | place[i] = 0; |
---|
555 | place[root->index - 1] = 1; |
---|
556 | for (i = 1; i <= (spp); i++) { |
---|
557 | p = treenode[i - 1]; |
---|
558 | while (place[p->index - 1] == 0) { |
---|
559 | place[p->index - 1] = i; |
---|
560 | while (!p->bottom) |
---|
561 | p = p->next; |
---|
562 | p = p->back; |
---|
563 | } |
---|
564 | if (i > 1) { |
---|
565 | place[i - 1] = place[p->index - 1]; |
---|
566 | j = place[p->index - 1]; |
---|
567 | done = false; |
---|
568 | while (!done) { |
---|
569 | place[p->index - 1] = spp + i - 1; |
---|
570 | while (!p->bottom) |
---|
571 | p = p->next; |
---|
572 | p = p->back; |
---|
573 | done = (p == NULL); |
---|
574 | if (!done) |
---|
575 | done = (place[p->index - 1] != j); |
---|
576 | } |
---|
577 | } |
---|
578 | } |
---|
579 | } /* savetree */ |
---|
580 | |
---|
581 | |
---|
582 | void mix_addtree(long *pos) |
---|
583 | { |
---|
584 | /* puts tree from ARRAY place in its proper position |
---|
585 | in ARRAY bestrees */ |
---|
586 | long i; |
---|
587 | for (i =nextree - 1; i >= (*pos); i--) |
---|
588 | memcpy(bestrees[i], bestrees[i - 1], spp*sizeof(long)); |
---|
589 | for (i = 0; i < (spp); i++) |
---|
590 | bestrees[(*pos) - 1][i] = place[i]; |
---|
591 | nextree++; |
---|
592 | } /* mix_addtree */ |
---|
593 | |
---|
594 | |
---|
595 | void mix_findtree(boolean *found, long *pos, long local_nextree, |
---|
596 | long *local_place, long **local_bestrees) |
---|
597 | { |
---|
598 | /* finds tree given by ARRAY local_place in ARRAY local_bestrees by binary search */ |
---|
599 | /* used by dnacomp, dnapars, dollop, mix, & protpars */ |
---|
600 | long i, lower, upper; |
---|
601 | boolean below, done; |
---|
602 | |
---|
603 | below = false; |
---|
604 | lower = 1; |
---|
605 | upper = local_nextree - 1; |
---|
606 | (*found) = false; |
---|
607 | while (!(*found) && lower <= upper) { |
---|
608 | (*pos) = (lower + upper) / 2; |
---|
609 | i = 3; |
---|
610 | done = false; |
---|
611 | while (!done) { |
---|
612 | done = (i > spp); |
---|
613 | if (!done) |
---|
614 | done = (local_place[i - 1] != local_bestrees[(*pos) - 1][i - 1]); |
---|
615 | if (!done) |
---|
616 | i++; |
---|
617 | } |
---|
618 | (*found) = (i > spp); |
---|
619 | below = (local_place[i - 1] < local_bestrees[(*pos )- 1][i - 1]); |
---|
620 | if (*found) |
---|
621 | break; |
---|
622 | if (below) |
---|
623 | upper = (*pos) - 1; |
---|
624 | else |
---|
625 | lower = (*pos) + 1; |
---|
626 | } |
---|
627 | if (!(*found) && !below) |
---|
628 | (*pos)++; |
---|
629 | } /* mix_findtree */ |
---|
630 | |
---|
631 | |
---|
632 | void tryadd(node2 *p, node2 **item, node2 **nufork) |
---|
633 | { |
---|
634 | /* temporarily adds one fork and one tip to the tree. |
---|
635 | if the location where they are added yields greater |
---|
636 | "likelihood" than other locations tested up to that |
---|
637 | time, then keeps that location as there */ |
---|
638 | |
---|
639 | long pos; |
---|
640 | boolean found; |
---|
641 | node2 *rute; |
---|
642 | |
---|
643 | add3(p, *item, *nufork, &root, treenode); |
---|
644 | evaluate(root); |
---|
645 | if (lastrearr) { |
---|
646 | if (like >= bstlike2) { |
---|
647 | rute = root->next->back; |
---|
648 | savetree(); |
---|
649 | reroot(rute); |
---|
650 | if (like > bstlike2) { |
---|
651 | bestlike = bstlike2 = like; |
---|
652 | pos = 1; |
---|
653 | nextree = 1; |
---|
654 | mix_addtree(&pos); |
---|
655 | } else { |
---|
656 | pos = 0; |
---|
657 | mix_findtree(&found, &pos, nextree, place, bestrees); |
---|
658 | if (!found) { |
---|
659 | if (nextree <= maxtrees) |
---|
660 | mix_addtree(&pos); |
---|
661 | } |
---|
662 | } |
---|
663 | } |
---|
664 | } |
---|
665 | if (like > bestyet) { |
---|
666 | bestyet = like; |
---|
667 | there = p; |
---|
668 | } |
---|
669 | re_move3(item, nufork, &root, treenode); |
---|
670 | } /* tryadd */ |
---|
671 | |
---|
672 | |
---|
673 | void addpreorder(node2 *p, node2 *item, node2 *nufork) |
---|
674 | { |
---|
675 | /* traverses a binary tree, calling PROCEDURE tryadd |
---|
676 | at a node before calling tryadd at its descendants */ |
---|
677 | |
---|
678 | if (p == NULL) |
---|
679 | return; |
---|
680 | tryadd(p, &item, &nufork); |
---|
681 | if (!p->tip) { |
---|
682 | addpreorder(p->next->back, item, nufork); |
---|
683 | addpreorder(p->next->next->back, item, nufork); |
---|
684 | } |
---|
685 | } /* addpreorder */ |
---|
686 | |
---|
687 | |
---|
688 | void tryrearr(node2 *p, node2 **r, boolean *success) |
---|
689 | { |
---|
690 | /* evaluates one rearrangement of the tree. |
---|
691 | if the new tree has greater "likelihood" than the old |
---|
692 | one sets success := TRUE and keeps the new tree. |
---|
693 | otherwise, restores the old tree */ |
---|
694 | node2 *frombelow, *whereto, *forknode; |
---|
695 | double oldlike; |
---|
696 | |
---|
697 | if (p->back == NULL) |
---|
698 | return; |
---|
699 | forknode = treenode[p->back->index - 1]; |
---|
700 | if (forknode->back == NULL) |
---|
701 | return; |
---|
702 | oldlike = bestyet; |
---|
703 | if (p->back->next->next == forknode) |
---|
704 | frombelow = forknode->next->next->back; |
---|
705 | else |
---|
706 | frombelow = forknode->next->back; |
---|
707 | whereto = treenode[forknode->back->index - 1]; |
---|
708 | re_move3(&p, &forknode, &root, treenode); |
---|
709 | add3(whereto, p, forknode, &root, treenode); |
---|
710 | evaluate(*r); |
---|
711 | if (like <= oldlike) { |
---|
712 | re_move3(&p, &forknode, &root, treenode); |
---|
713 | add3(frombelow, p, forknode, &root, treenode); |
---|
714 | } else { |
---|
715 | *success = true; |
---|
716 | bestyet = like; |
---|
717 | } |
---|
718 | } /* tryrearr */ |
---|
719 | |
---|
720 | |
---|
721 | void repreorder(node2 *p, node2 **r, boolean *success) |
---|
722 | { |
---|
723 | /* traverses a binary tree, calling PROCEDURE tryrearr |
---|
724 | at a node before calling tryrearr at its descendants */ |
---|
725 | if (p == NULL) |
---|
726 | return; |
---|
727 | tryrearr(p, r, success); |
---|
728 | if (!p->tip) { |
---|
729 | repreorder(p->next->back, r,success); |
---|
730 | repreorder(p->next->next->back, r,success); |
---|
731 | } |
---|
732 | } /* repreorder */ |
---|
733 | |
---|
734 | |
---|
735 | void rearrange(node2 **r) |
---|
736 | { |
---|
737 | /* traverses the tree (preorder), finding any local |
---|
738 | rearrangement which decreases the number of steps. |
---|
739 | if traversal succeeds in increasing the tree's |
---|
740 | "likelihood", PROCEDURE rearrange runs traversal again */ |
---|
741 | boolean success=true; |
---|
742 | while (success) { |
---|
743 | success = false; |
---|
744 | repreorder(*r,r,&success); |
---|
745 | } |
---|
746 | } /* rearrange */ |
---|
747 | |
---|
748 | |
---|
749 | void mix_addelement(node2 **p, long *nextnode, long *lparens, |
---|
750 | boolean *names) |
---|
751 | { |
---|
752 | /* recursive procedure adds nodes to user-defined tree */ |
---|
753 | node2 *q; |
---|
754 | long i, n; |
---|
755 | boolean found; |
---|
756 | Char str[nmlngth]; |
---|
757 | |
---|
758 | getch(&global_ch, lparens, intree); |
---|
759 | if (global_ch == '(' ) { |
---|
760 | if ((*lparens) >= spp) { |
---|
761 | printf("\n\nERROR IN USER TREE: Too many left parentheses\n\n"); |
---|
762 | exxit(-1); |
---|
763 | } |
---|
764 | (*nextnode)++; |
---|
765 | q = treenode[(*nextnode) - 1]; |
---|
766 | mix_addelement(&q->next->back, nextnode, lparens, names); |
---|
767 | q->next->back->back = q->next; |
---|
768 | findch(',', &global_ch, which); |
---|
769 | mix_addelement(&q->next->next->back, nextnode, lparens, names); |
---|
770 | q->next->next->back->back = q->next->next; |
---|
771 | findch(')', &global_ch, which); |
---|
772 | *p = q; |
---|
773 | return; |
---|
774 | } |
---|
775 | for (i = 0; i < nmlngth; i++) |
---|
776 | str[i] = ' '; |
---|
777 | n = 1; |
---|
778 | do { |
---|
779 | if (global_ch == '_') |
---|
780 | global_ch = ' '; |
---|
781 | str[n - 1] =global_ch; |
---|
782 | if (eoln(intree)) |
---|
783 | scan_eoln(intree); |
---|
784 | global_ch = gettc(intree); |
---|
785 | if (global_ch == '\n') |
---|
786 | global_ch = ' '; |
---|
787 | n++; |
---|
788 | } while (global_ch != ',' && global_ch != ')' && global_ch != ':' && n <= nmlngth); |
---|
789 | n = 1; |
---|
790 | do { |
---|
791 | found = true; |
---|
792 | for (i = 0; i < nmlngth; i++) |
---|
793 | found = (found && ((str[i] == nayme[n - 1][i]) || |
---|
794 | ((nayme[n - 1][i] == '_') && (str[i] == ' ')))); |
---|
795 | if (found) { |
---|
796 | if (names[n - 1] == false) { |
---|
797 | *p = treenode[n - 1]; |
---|
798 | names[n - 1] = true; |
---|
799 | } else { |
---|
800 | printf("\n\nERROR IN USER TREE: Duplicate name found: "); |
---|
801 | for (i = 0; i < nmlngth; i++) |
---|
802 | putchar(nayme[n - 1][i]); |
---|
803 | printf("\n\n"); |
---|
804 | exxit(-1); |
---|
805 | } |
---|
806 | } else |
---|
807 | n++; |
---|
808 | } while (!(n > spp || found )); |
---|
809 | if (n <= spp) |
---|
810 | return; |
---|
811 | printf("CANNOT FIND SPECIES: "); |
---|
812 | for (i = 0; i < nmlngth; i++) |
---|
813 | putchar(str[i]); |
---|
814 | putchar('\n'); |
---|
815 | } /* mix_addelement */ |
---|
816 | |
---|
817 | |
---|
818 | void mix_treeread() |
---|
819 | { |
---|
820 | /* read in user-defined tree and set it up */ |
---|
821 | long nextnode, lparens, i; |
---|
822 | boolean *names; |
---|
823 | |
---|
824 | root = treenode[spp]; |
---|
825 | nextnode = spp; |
---|
826 | root->back = NULL; |
---|
827 | names = (boolean *)Malloc(spp*sizeof(boolean)); |
---|
828 | for (i = 0; i < (spp); i++) |
---|
829 | names[i] = false; |
---|
830 | lparens = 0; |
---|
831 | mix_addelement(&root, &nextnode, &lparens, names); |
---|
832 | if (global_ch == '[') { |
---|
833 | do |
---|
834 | global_ch = gettc(intree); |
---|
835 | while (global_ch != ']'); |
---|
836 | global_ch = gettc(intree); |
---|
837 | } |
---|
838 | findch(';', &global_ch, which); |
---|
839 | if (progress) |
---|
840 | printf("."); |
---|
841 | scan_eoln(intree); |
---|
842 | free(names); |
---|
843 | } /* mix_treeread */ |
---|
844 | |
---|
845 | |
---|
846 | void describe() |
---|
847 | { |
---|
848 | /* prints ancestors, steps and table of numbers of steps in |
---|
849 | each character */ |
---|
850 | |
---|
851 | if (treeprint) |
---|
852 | fprintf(outfile, "\nrequires a total of %10.3f\n", -like); |
---|
853 | putc('\n', outfile); |
---|
854 | if (stepbox) |
---|
855 | writesteps(weights, numsteps); |
---|
856 | if (questions && (!noroot || didreroot)) |
---|
857 | guesstates(guess); |
---|
858 | if (ancseq) { |
---|
859 | hypstates(fullset, full, noroot, didreroot, root, wagner, |
---|
860 | zeroanc, oneanc, treenode, guess, garbage); |
---|
861 | putc('\n', outfile); |
---|
862 | } |
---|
863 | putc('\n', outfile); |
---|
864 | if (trout) { |
---|
865 | col = 0; |
---|
866 | treeout2(root, &col, root); |
---|
867 | } |
---|
868 | } /* describe */ |
---|
869 | |
---|
870 | |
---|
871 | void maketree() |
---|
872 | { |
---|
873 | /* constructs a binary tree from the pointers in treenode. |
---|
874 | adds each node at location which yields highest "likelihood" |
---|
875 | then rearranges the tree for greatest "likelihood" */ |
---|
876 | long i, j, numtrees; |
---|
877 | double gotlike; |
---|
878 | node2 *item, *nufork, *dummy; |
---|
879 | |
---|
880 | fullset = (1L << (bits + 1)) - (1L << 1); |
---|
881 | for (i=0 ; i<words ; ++i){ |
---|
882 | fulzeroanc[i]=fullset; |
---|
883 | empzeroanc[i]= 0;} |
---|
884 | if (!usertree) { |
---|
885 | for (i = 1; i <= (spp); i++) |
---|
886 | enterorder[i - 1] = i; |
---|
887 | if (jumble) |
---|
888 | randumize(seed, enterorder); |
---|
889 | root = treenode[enterorder[0] - 1]; |
---|
890 | add3(treenode[enterorder[0] - 1], treenode[enterorder[1] - 1], |
---|
891 | treenode[spp], &root, treenode); |
---|
892 | if (progress) { |
---|
893 | printf("Adding species:\n"); |
---|
894 | writename(0, 2, enterorder); |
---|
895 | #ifdef WIN32 |
---|
896 | phyFillScreenColor(); |
---|
897 | #endif |
---|
898 | } |
---|
899 | lastrearr = false; |
---|
900 | for (i = 3; i <= (spp); i++) { |
---|
901 | bestyet = -350.0 * spp * chars; |
---|
902 | item = treenode[enterorder[i - 1] - 1]; |
---|
903 | nufork = treenode[spp + i - 2]; |
---|
904 | addpreorder(root, item, nufork); |
---|
905 | add3(there, item, nufork, &root, treenode); |
---|
906 | like = bestyet; |
---|
907 | rearrange(&root); |
---|
908 | if (progress) { |
---|
909 | writename(i - 1, 1, enterorder); |
---|
910 | #ifdef WIN32 |
---|
911 | phyFillScreenColor(); |
---|
912 | #endif |
---|
913 | } |
---|
914 | lastrearr = (i == spp); |
---|
915 | if (lastrearr) { |
---|
916 | if (progress) { |
---|
917 | printf("\nDoing global rearrangements\n"); |
---|
918 | printf(" !"); |
---|
919 | for (j = 1; j <= (nonodes); j++) |
---|
920 | putchar('-'); |
---|
921 | printf("!\n"); |
---|
922 | #ifdef WIN32 |
---|
923 | phyFillScreenColor(); |
---|
924 | #endif |
---|
925 | } |
---|
926 | bestlike = bestyet; |
---|
927 | if (jumb == 1) { |
---|
928 | bstlike2 = bestlike; |
---|
929 | nextree = 1; |
---|
930 | } |
---|
931 | do { |
---|
932 | if (progress) |
---|
933 | printf(" "); |
---|
934 | gotlike = bestlike; |
---|
935 | for (j = 0; j < (nonodes); j++) { |
---|
936 | bestyet = -350.0 * spp * chars; |
---|
937 | item = treenode[j]; |
---|
938 | if (item != root) { |
---|
939 | re_move3(&item, &nufork, &root, treenode); |
---|
940 | there = root; |
---|
941 | addpreorder(root, item, nufork); |
---|
942 | add3(there, item, nufork, &root, treenode); |
---|
943 | } |
---|
944 | if (progress) { |
---|
945 | putchar('.'); |
---|
946 | fflush(stdout); |
---|
947 | } |
---|
948 | } |
---|
949 | if (progress) { |
---|
950 | putchar('\n'); |
---|
951 | #ifdef WIN32 |
---|
952 | phyFillScreenColor(); |
---|
953 | #endif |
---|
954 | } |
---|
955 | } while (bestlike > gotlike); |
---|
956 | } |
---|
957 | } |
---|
958 | if (progress) |
---|
959 | putchar('\n'); |
---|
960 | for (i = spp - 1; i >= 1; i--) |
---|
961 | re_move3(&treenode[i], &dummy, &root, treenode); |
---|
962 | if (jumb == njumble) { |
---|
963 | if (treeprint) { |
---|
964 | putc('\n', outfile); |
---|
965 | if (nextree == 2) |
---|
966 | fprintf(outfile, "One most parsimonious tree found:\n"); |
---|
967 | else |
---|
968 | fprintf(outfile, "%6ld trees in all found\n", nextree - 1); |
---|
969 | } |
---|
970 | if (nextree > maxtrees + 1) { |
---|
971 | if (treeprint) |
---|
972 | fprintf(outfile, "here are the first%4ld of them\n",(long)maxtrees); |
---|
973 | nextree = maxtrees + 1; |
---|
974 | } |
---|
975 | if (treeprint) |
---|
976 | putc('\n', outfile); |
---|
977 | for (i = 0; i <= (nextree - 2); i++) { |
---|
978 | root = treenode[0]; |
---|
979 | add3(treenode[0], treenode[1], treenode[spp], &root, treenode); |
---|
980 | for (j = 3; j <= (spp); j++) |
---|
981 | add3(treenode[bestrees[i][j - 1] - 1], treenode[j - 1], |
---|
982 | treenode[spp + j - 2], &root, treenode); |
---|
983 | if (noroot) |
---|
984 | reroot(treenode[outgrno - 1]); |
---|
985 | didreroot = (outgropt && noroot); |
---|
986 | evaluate(root); |
---|
987 | printree(treeprint, noroot, didreroot, root); |
---|
988 | describe(); |
---|
989 | for (j = 1; j < (spp); j++) |
---|
990 | re_move3(&treenode[j], &dummy, &root, treenode); |
---|
991 | } |
---|
992 | } |
---|
993 | } else { |
---|
994 | openfile(&intree,INTREE,"input tree file", "r",progname,intreename); |
---|
995 | numtrees = countsemic(&intree); |
---|
996 | if (numtrees > 2) |
---|
997 | initseed(&inseed, &inseed0, seed); |
---|
998 | if (treeprint) { |
---|
999 | fprintf(outfile, "User-defined tree"); |
---|
1000 | if (numtrees > 1) |
---|
1001 | putc('s', outfile); |
---|
1002 | fprintf(outfile, ":\n\n"); |
---|
1003 | } |
---|
1004 | which = 1; |
---|
1005 | if (progress) |
---|
1006 | printf(" "); |
---|
1007 | while (which <= numtrees ) { |
---|
1008 | mix_treeread(); |
---|
1009 | didreroot = (outgropt && noroot); |
---|
1010 | if (noroot) |
---|
1011 | reroot(treenode[outgrno - 1]); |
---|
1012 | evaluate(root); |
---|
1013 | printree(treeprint, noroot, didreroot, root); |
---|
1014 | describe(); |
---|
1015 | which++; |
---|
1016 | } |
---|
1017 | if (progress) |
---|
1018 | printf("\n"); |
---|
1019 | FClose(intree); |
---|
1020 | fprintf(outfile, "\n\n"); |
---|
1021 | if (numtrees > 2 && chars > 1 ) { |
---|
1022 | if (progress) |
---|
1023 | printf(" sampling for SH test\n"); |
---|
1024 | standev(numtrees, minwhich, minsteps, nsteps, fsteps, seed); |
---|
1025 | } |
---|
1026 | } |
---|
1027 | if (jumb == njumble) { |
---|
1028 | if (progress) { |
---|
1029 | printf("\nOutput written to file \"%s\"\n\n", outfilename); |
---|
1030 | if (trout) |
---|
1031 | printf("Trees also written onto file \"%s\"\n", outtreename); |
---|
1032 | putchar('\n'); |
---|
1033 | } |
---|
1034 | } |
---|
1035 | if (ancseq) |
---|
1036 | freegarbage(&garbage); |
---|
1037 | } /* maketree */ |
---|
1038 | |
---|
1039 | int main(int argc, Char *argv[]) |
---|
1040 | { /* Mixed parsimony by uphill search */ |
---|
1041 | #ifdef MAC |
---|
1042 | argc = 1; /* macsetup("Mix",""); */ |
---|
1043 | argv[0] = "Mix"; |
---|
1044 | #endif |
---|
1045 | init(argc, argv); |
---|
1046 | progname = argv[0]; |
---|
1047 | openfile(&infile,INFILE,"input file", "r",argv[0],infilename); |
---|
1048 | openfile(&outfile,OUTFILE,"output file", "w",argv[0],outfilename); |
---|
1049 | |
---|
1050 | ibmpc = IBMCRT; |
---|
1051 | ansi = ANSICRT; |
---|
1052 | mulsets = false; |
---|
1053 | msets = 1; |
---|
1054 | firstset = true; |
---|
1055 | garbage = NULL; |
---|
1056 | bits = 8*sizeof(long) - 1; |
---|
1057 | doinit(); |
---|
1058 | if (weights || justwts) |
---|
1059 | openfile(&weightfile,WEIGHTFILE,"weights file","r",argv[0],weightfilename); |
---|
1060 | if (trout) |
---|
1061 | openfile(&outtree,OUTTREE,"output tree file", "w",argv[0],outtreename); |
---|
1062 | if(ancvar) |
---|
1063 | openfile(&ancfile,ANCFILE,"ancestors file", "r",argv[0],ancfilename); |
---|
1064 | if(mixture) |
---|
1065 | openfile(&mixfile,MIXFILE,"mixture file", "r",argv[0],mixfilename); |
---|
1066 | |
---|
1067 | for (ith = 1; ith <= msets; ith++) { |
---|
1068 | if(firstset){ |
---|
1069 | if (allsokal && !mixture) |
---|
1070 | fprintf(outfile, "Camin-Sokal parsimony method\n\n"); |
---|
1071 | if (allwagner && !mixture) |
---|
1072 | fprintf(outfile, "Wagner parsimony method\n\n"); |
---|
1073 | } |
---|
1074 | doinput(); |
---|
1075 | if (msets > 1 && !justwts) { |
---|
1076 | fprintf(outfile, "Data set # %ld:\n\n",ith); |
---|
1077 | if (progress) |
---|
1078 | printf("\nData set # %ld:\n",ith); |
---|
1079 | } |
---|
1080 | if (justwts){ |
---|
1081 | if(firstset && mixture && printdata) |
---|
1082 | printmixture(outfile, wagner); |
---|
1083 | fprintf(outfile, "Weights set # %ld:\n\n", ith); |
---|
1084 | if (progress) |
---|
1085 | printf("\nWeights set # %ld:\n\n", ith); |
---|
1086 | } |
---|
1087 | else if (mixture && printdata) |
---|
1088 | printmixture(outfile, wagner); |
---|
1089 | if (printdata){ |
---|
1090 | if (weights || justwts) |
---|
1091 | printweights(outfile, 0, chars, weight, "Characters"); |
---|
1092 | if (ancvar) |
---|
1093 | printancestors(outfile, anczero, ancone); |
---|
1094 | } |
---|
1095 | |
---|
1096 | |
---|
1097 | if (ith == 1) |
---|
1098 | firstset = false; |
---|
1099 | for (jumb = 1; jumb <= njumble; jumb++) |
---|
1100 | maketree(); |
---|
1101 | } |
---|
1102 | free(place); |
---|
1103 | free(steps); |
---|
1104 | free(zeroanc); |
---|
1105 | free(oneanc); |
---|
1106 | free(fulzeroanc); |
---|
1107 | free(empzeroanc); |
---|
1108 | FClose(outfile); |
---|
1109 | FClose(infile); |
---|
1110 | FClose(outtree); |
---|
1111 | #ifdef MAC |
---|
1112 | fixmacfile(outtreename); |
---|
1113 | fixmacfile(outfilename); |
---|
1114 | #endif |
---|
1115 | #ifdef WIN32 |
---|
1116 | phyRestoreConsoleAttributes(); |
---|
1117 | #endif |
---|
1118 | return 0; |
---|
1119 | } /* Mixed parsimony by uphill search */ |
---|