1 | /* RAxML-VI-HPC (version 2.2) a program for sequential and parallel estimation of phylogenetic trees |
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2 | * Copyright August 2006 by Alexandros Stamatakis |
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3 | * |
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4 | * Partially derived from |
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5 | * fastDNAml, a program for estimation of phylogenetic trees from sequences by Gary J. Olsen |
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6 | * |
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7 | * and |
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8 | * |
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9 | * Programs of the PHYLIP package by Joe Felsenstein. |
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10 | * |
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11 | * This program is free software; you may redistribute it and/or modify its |
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12 | * under the terms of the GNU General Public License as published by the Free |
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13 | * Software Foundation; either version 2 of the License, or (at your option) |
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14 | * any later version. |
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15 | * |
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16 | * This program is distributed in the hope that it will be useful, but |
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17 | * WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY |
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18 | * or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License |
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19 | * for more details. |
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20 | * |
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21 | * |
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22 | * For any other enquiries send an Email to Alexandros Stamatakis |
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23 | * Alexandros.Stamatakis@epfl.ch |
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24 | * |
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25 | * When publishing work that is based on the results from RAxML-VI-HPC please cite: |
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26 | * |
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27 | * Alexandros Stamatakis:"RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models". |
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28 | * Bioinformatics 2006; doi: 10.1093/bioinformatics/btl446 |
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29 | */ |
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30 | |
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31 | #ifndef WIN32 |
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32 | #include <sys/times.h> |
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33 | #include <sys/types.h> |
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34 | #include <sys/time.h> |
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35 | #include <unistd.h> |
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36 | #endif |
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37 | |
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38 | #include <math.h> |
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39 | #include <time.h> |
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40 | #include <stdlib.h> |
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41 | #include <stdio.h> |
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42 | #include <ctype.h> |
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43 | #include <string.h> |
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44 | |
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45 | #include "axml.h" |
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46 | |
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47 | extern FILE *INFILE; |
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48 | extern char infoFileName[1024]; |
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49 | extern char tree_file[1024]; |
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50 | extern char *likelihood_key; |
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51 | extern char *ntaxa_key; |
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52 | extern char *smoothed_key; |
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53 | extern int partCount; |
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54 | extern double masterTime; |
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55 | |
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56 | |
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57 | |
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58 | |
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59 | |
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60 | stringHashtable *initStringHashTable(hashNumberType n) |
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61 | { |
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62 | /* |
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63 | init with primes |
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64 | */ |
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65 | |
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66 | static const hashNumberType initTable[] = {53, 97, 193, 389, 769, 1543, 3079, 6151, 12289, 24593, 49157, 98317, |
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67 | 196613, 393241, 786433, 1572869, 3145739, 6291469, 12582917, 25165843, |
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68 | 50331653, 100663319, 201326611, 402653189, 805306457, 1610612741}; |
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69 | |
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70 | |
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71 | /* init with powers of two |
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72 | |
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73 | static const hashNumberType initTable[] = {64, 128, 256, 512, 1024, 2048, 4096, 8192, 16384, |
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74 | 32768, 65536, 131072, 262144, 524288, 1048576, 2097152, |
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75 | 4194304, 8388608, 16777216, 33554432, 67108864, 134217728, |
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76 | 268435456, 536870912, 1073741824, 2147483648U}; |
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77 | */ |
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78 | |
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79 | stringHashtable *h = (stringHashtable*)rax_malloc(sizeof(stringHashtable)); |
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80 | |
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81 | hashNumberType |
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82 | tableSize, |
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83 | i, |
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84 | primeTableLength = sizeof(initTable)/sizeof(initTable[0]), |
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85 | maxSize = (hashNumberType)-1; |
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86 | |
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87 | assert(n <= maxSize); |
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88 | |
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89 | i = 0; |
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90 | |
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91 | while(initTable[i] < n && i < primeTableLength) |
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92 | i++; |
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93 | |
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94 | assert(i < primeTableLength); |
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95 | |
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96 | tableSize = initTable[i]; |
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97 | |
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98 | h->table = (stringEntry**)rax_calloc(tableSize, sizeof(stringEntry*)); |
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99 | h->tableSize = tableSize; |
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100 | |
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101 | return h; |
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102 | } |
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103 | |
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104 | |
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105 | static hashNumberType hashString(char *p, hashNumberType tableSize) |
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106 | { |
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107 | hashNumberType h = 0; |
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108 | |
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109 | for(; *p; p++) |
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110 | h = 31 * h + *p; |
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111 | |
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112 | return (h % tableSize); |
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113 | } |
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114 | |
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115 | |
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116 | |
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117 | void addword(char *s, stringHashtable *h, int nodeNumber) |
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118 | { |
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119 | hashNumberType position = hashString(s, h->tableSize); |
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120 | stringEntry *p = h->table[position]; |
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121 | |
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122 | for(; p!= NULL; p = p->next) |
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123 | { |
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124 | if(strcmp(s, p->word) == 0) |
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125 | return; |
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126 | } |
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127 | |
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128 | p = (stringEntry *)rax_malloc(sizeof(stringEntry)); |
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129 | |
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130 | assert(p); |
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131 | |
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132 | p->nodeNumber = nodeNumber; |
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133 | p->word = (char *)rax_malloc((strlen(s) + 1) * sizeof(char)); |
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134 | |
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135 | strcpy(p->word, s); |
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136 | |
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137 | p->next = h->table[position]; |
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138 | |
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139 | h->table[position] = p; |
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140 | } |
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141 | |
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142 | int lookupWord(char *s, stringHashtable *h) |
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143 | { |
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144 | hashNumberType position = hashString(s, h->tableSize); |
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145 | stringEntry *p = h->table[position]; |
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146 | |
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147 | for(; p!= NULL; p = p->next) |
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148 | { |
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149 | if(strcmp(s, p->word) == 0) |
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150 | return p->nodeNumber; |
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151 | } |
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152 | |
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153 | return -1; |
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154 | } |
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155 | |
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156 | |
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157 | int countTips(nodeptr p, int numsp) |
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158 | { |
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159 | if(isTip(p->number, numsp)) |
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160 | return 1; |
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161 | { |
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162 | nodeptr q; |
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163 | int tips = 0; |
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164 | |
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165 | q = p->next; |
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166 | while(q != p) |
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167 | { |
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168 | tips += countTips(q->back, numsp); |
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169 | q = q->next; |
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170 | } |
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171 | |
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172 | return tips; |
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173 | } |
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174 | } |
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175 | |
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176 | |
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177 | static double getBranchLength(tree *tr, int perGene, nodeptr p) |
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178 | { |
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179 | double |
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180 | z = 0.0, |
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181 | x = 0.0; |
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182 | |
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183 | assert(perGene != NO_BRANCHES); |
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184 | |
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185 | if(!tr->multiBranch) |
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186 | { |
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187 | assert(tr->fracchange != -1.0); |
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188 | z = p->z[0]; |
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189 | if (z < zmin) |
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190 | z = zmin; |
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191 | |
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192 | x = -log(z) * tr->fracchange; |
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193 | } |
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194 | else |
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195 | { |
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196 | if(perGene == SUMMARIZE_LH) |
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197 | { |
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198 | int |
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199 | i; |
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200 | |
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201 | double |
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202 | avgX = 0.0; |
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203 | |
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204 | for(i = 0; i < tr->numBranches; i++) |
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205 | { |
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206 | assert(tr->partitionContributions[i] != -1.0); |
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207 | assert(tr->fracchanges[i] != -1.0); |
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208 | z = p->z[i]; |
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209 | if(z < zmin) |
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210 | z = zmin; |
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211 | x = -log(z) * tr->fracchanges[i]; |
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212 | avgX += x * tr->partitionContributions[i]; |
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213 | } |
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214 | |
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215 | x = avgX; |
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216 | } |
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217 | else |
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218 | { |
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219 | assert(tr->fracchanges[perGene] != -1.0); |
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220 | assert(perGene >= 0 && perGene < tr->numBranches); |
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221 | |
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222 | z = p->z[perGene]; |
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223 | |
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224 | if(z < zmin) |
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225 | z = zmin; |
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226 | |
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227 | x = -log(z) * tr->fracchanges[perGene]; |
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228 | } |
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229 | } |
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230 | |
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231 | return x; |
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232 | } |
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233 | |
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234 | |
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235 | |
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236 | |
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237 | |
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238 | static char *Tree2StringREC(char *treestr, tree *tr, nodeptr p, boolean printBranchLengths, boolean printNames, |
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239 | boolean printLikelihood, boolean rellTree, boolean finalPrint, int perGene, boolean branchLabelSupport, boolean printSHSupport, boolean printIC, boolean printSHSupports) |
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240 | { |
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241 | char *nameptr; |
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242 | |
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243 | if(isTip(p->number, tr->rdta->numsp)) |
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244 | { |
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245 | if(printNames) |
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246 | { |
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247 | nameptr = tr->nameList[p->number]; |
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248 | sprintf(treestr, "%s", nameptr); |
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249 | } |
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250 | else |
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251 | sprintf(treestr, "%d", p->number); |
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252 | |
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253 | while (*treestr) treestr++; |
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254 | } |
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255 | else |
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256 | { |
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257 | *treestr++ = '('; |
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258 | treestr = Tree2StringREC(treestr, tr, p->next->back, printBranchLengths, printNames, printLikelihood, rellTree, |
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259 | finalPrint, perGene, branchLabelSupport, printSHSupport, printIC, printSHSupports); |
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260 | *treestr++ = ','; |
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261 | treestr = Tree2StringREC(treestr, tr, p->next->next->back, printBranchLengths, printNames, printLikelihood, rellTree, |
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262 | finalPrint, perGene, branchLabelSupport, printSHSupport, printIC, printSHSupports); |
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263 | if(p == tr->start->back) |
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264 | { |
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265 | *treestr++ = ','; |
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266 | treestr = Tree2StringREC(treestr, tr, p->back, printBranchLengths, printNames, printLikelihood, rellTree, |
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267 | finalPrint, perGene, branchLabelSupport, printSHSupport, printIC, printSHSupports); |
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268 | } |
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269 | *treestr++ = ')'; |
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270 | } |
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271 | |
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272 | if(p == tr->start->back) |
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273 | { |
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274 | if(printBranchLengths && !rellTree) |
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275 | sprintf(treestr, ":0.0;\n"); |
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276 | else |
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277 | sprintf(treestr, ";\n"); |
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278 | } |
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279 | else |
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280 | { |
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281 | if(rellTree || branchLabelSupport || printSHSupport || printIC || printSHSupports) |
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282 | { |
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283 | if(( !isTip(p->number, tr->rdta->numsp)) && |
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284 | ( !isTip(p->back->number, tr->rdta->numsp))) |
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285 | { |
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286 | assert(p->bInf != (branchInfo *)NULL); |
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287 | |
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288 | assert(rellTree + branchLabelSupport + printSHSupport + printSHSupports == 1); |
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289 | |
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290 | if(rellTree) |
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291 | { |
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292 | if(printIC) |
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293 | sprintf(treestr, "%1.2f:%8.20f", p->bInf->ic, p->z[0]); |
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294 | else |
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295 | sprintf(treestr, "%d:%8.20f", p->bInf->support, p->z[0]); |
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296 | } |
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297 | |
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298 | if(branchLabelSupport) |
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299 | { |
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300 | if(printIC) |
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301 | sprintf(treestr, ":%8.20f[%1.2f,%1.2f]", p->z[0], p->bInf->ic, p->bInf->icAll); |
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302 | else |
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303 | sprintf(treestr, ":%8.20f[%d]", p->z[0], p->bInf->support); |
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304 | } |
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305 | |
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306 | if(printSHSupport) |
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307 | sprintf(treestr, ":%8.20f[%d]", getBranchLength(tr, perGene, p), p->bInf->support); |
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308 | |
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309 | if(printSHSupports) |
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310 | { |
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311 | int |
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312 | model; |
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313 | |
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314 | sprintf(treestr, ":%8.20f[", getBranchLength(tr, perGene, p)); |
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315 | while(*treestr) |
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316 | treestr++; |
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317 | |
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318 | for(model = 0; model < tr->NumberOfModels - 1; model++) |
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319 | { |
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320 | sprintf(treestr, "%d,", p->bInf->supports[model]); |
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321 | while(*treestr) |
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322 | treestr++; |
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323 | } |
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324 | |
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325 | sprintf(treestr, "%d]", p->bInf->supports[model]); |
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326 | } |
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327 | |
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328 | } |
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329 | else |
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330 | { |
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331 | if(rellTree || branchLabelSupport) |
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332 | sprintf(treestr, ":%8.20f", p->z[0]); |
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333 | if(printSHSupport || printSHSupports) |
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334 | sprintf(treestr, ":%8.20f", getBranchLength(tr, perGene, p)); |
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335 | } |
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336 | } |
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337 | else |
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338 | { |
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339 | if(printBranchLengths) |
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340 | sprintf(treestr, ":%8.20f", getBranchLength(tr, perGene, p)); |
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341 | else |
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342 | sprintf(treestr, "%s", "\0"); |
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343 | } |
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344 | } |
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345 | |
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346 | while (*treestr) treestr++; |
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347 | return treestr; |
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348 | } |
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349 | |
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350 | |
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351 | static void collectSubtrees(tree *tr, nodeptr *subtrees, int *count, int ogn) |
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352 | { |
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353 | int i; |
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354 | for(i = tr->mxtips + 1; i <= tr->mxtips + tr->mxtips - 2; i++) |
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355 | { |
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356 | nodeptr p, q; |
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357 | p = tr->nodep[i]; |
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358 | if(countTips(p, tr->rdta->numsp) == ogn) |
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359 | { |
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360 | subtrees[*count] = p; |
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361 | *count = *count + 1; |
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362 | } |
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363 | q = p->next; |
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364 | while(q != p) |
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365 | { |
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366 | if(countTips(q, tr->rdta->numsp) == ogn) |
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367 | { |
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368 | subtrees[*count] = q; |
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369 | *count = *count + 1; |
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370 | } |
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371 | q = q->next; |
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372 | } |
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373 | } |
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374 | } |
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375 | |
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376 | static void checkOM(nodeptr p, int *n, int *c, tree *tr) |
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377 | { |
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378 | if(isTip(p->number, tr->rdta->numsp)) |
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379 | { |
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380 | n[*c] = p->number; |
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381 | *c = *c + 1; |
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382 | } |
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383 | else |
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384 | { |
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385 | nodeptr q = p->next; |
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386 | |
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387 | while(q != p) |
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388 | { |
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389 | checkOM(q->back, n, c, tr); |
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390 | q = q->next; |
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391 | } |
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392 | } |
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393 | } |
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394 | |
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395 | static char *rootedTreeREC(char *treestr, tree *tr, nodeptr p, boolean printBranchLengths, boolean printNames, |
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396 | boolean printLikelihood, boolean rellTree, |
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397 | boolean finalPrint, analdef *adef, int perGene, boolean branchLabelSupport, boolean printSHSupport) |
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398 | { |
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399 | char *nameptr; |
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400 | |
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401 | if(isTip(p->number, tr->rdta->numsp)) |
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402 | { |
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403 | if(printNames) |
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404 | { |
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405 | nameptr = tr->nameList[p->number]; |
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406 | sprintf(treestr, "%s", nameptr); |
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407 | } |
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408 | else |
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409 | sprintf(treestr, "%d", p->number); |
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410 | |
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411 | while (*treestr) treestr++; |
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412 | } |
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413 | else |
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414 | { |
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415 | *treestr++ = '('; |
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416 | treestr = rootedTreeREC(treestr, tr, p->next->back, printBranchLengths, printNames, printLikelihood, |
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417 | rellTree, finalPrint, adef, perGene, branchLabelSupport, printSHSupport); |
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418 | *treestr++ = ','; |
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419 | treestr = rootedTreeREC(treestr, tr, p->next->next->back, printBranchLengths, printNames, printLikelihood, |
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420 | rellTree, finalPrint, adef, perGene, branchLabelSupport, printSHSupport); |
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421 | *treestr++ = ')'; |
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422 | } |
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423 | |
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424 | if(rellTree || branchLabelSupport || printSHSupport) |
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425 | { |
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426 | if(( !isTip(p->number, tr->rdta->numsp)) && |
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427 | ( !isTip(p->back->number, tr->rdta->numsp))) |
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428 | { |
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429 | assert(p->bInf != (branchInfo *)NULL); |
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430 | |
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431 | if(rellTree) |
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432 | sprintf(treestr, "%d:%8.20f", p->bInf->support, p->z[0]); |
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433 | if(branchLabelSupport) |
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434 | sprintf(treestr, ":%8.20f[%d]", p->z[0], p->bInf->support); |
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435 | if(printSHSupport) |
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436 | sprintf(treestr, ":%8.20f[%d]", getBranchLength(tr, perGene, p), p->bInf->support); |
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437 | } |
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438 | else |
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439 | { |
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440 | if(rellTree || branchLabelSupport) |
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441 | sprintf(treestr, ":%8.20f", p->z[0]); |
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442 | if(printSHSupport) |
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443 | sprintf(treestr, ":%8.20f", getBranchLength(tr, perGene, p)); |
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444 | } |
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445 | } |
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446 | else |
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447 | { |
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448 | if(printBranchLengths) |
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449 | sprintf(treestr, ":%8.20f", getBranchLength(tr, perGene, p)); |
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450 | else |
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451 | sprintf(treestr, "%s", "\0"); |
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452 | } |
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453 | |
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454 | while (*treestr) treestr++; |
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455 | return treestr; |
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456 | } |
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457 | |
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458 | static char *rootedTree(char *treestr, tree *tr, nodeptr p, boolean printBranchLengths, boolean printNames, |
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459 | boolean printLikelihood, boolean rellTree, |
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460 | boolean finalPrint, analdef *adef, int perGene, boolean branchLabelSupport, boolean printSHSupport) |
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461 | { |
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462 | double oldz[NUM_BRANCHES]; |
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463 | |
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464 | for(int i = 0; i < tr->numBranches; i++) |
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465 | oldz[i] = p->z[i]; |
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466 | |
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467 | if(rellTree) |
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468 | { |
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469 | p->z[0] = p->back->z[0] = oldz[0] * 0.5; |
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470 | /*printf("%f\n", p->z[0]);*/ |
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471 | } |
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472 | else |
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473 | { |
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474 | if(printBranchLengths) |
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475 | { |
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476 | double rz, z; |
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477 | assert(perGene != NO_BRANCHES); |
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478 | |
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479 | if(!tr->multiBranch) |
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480 | { |
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481 | assert(tr->fracchange != -1.0); |
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482 | z = -log(p->z[0]) * tr->fracchange; |
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483 | rz = exp(-(z * 0.5)/ tr->fracchange); |
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484 | p->z[0] = p->back->z[0] = rz; |
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485 | } |
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486 | else |
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487 | { |
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488 | if(perGene == SUMMARIZE_LH) |
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489 | { |
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490 | for(int i = 0; i < tr->numBranches; i++) |
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491 | { |
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492 | assert(tr->fracchanges[i] != -1.0); |
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493 | z = -log(p->z[i]) * tr->fracchanges[i]; |
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494 | rz = exp(-(z * 0.5)/ tr->fracchanges[i]); |
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495 | p->z[i] = p->back->z[i] = rz; |
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496 | } |
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497 | } |
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498 | else |
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499 | { |
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500 | assert(tr->fracchanges[perGene] != -1.0); |
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501 | assert(perGene >= 0 && perGene < tr->numBranches); |
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502 | z = -log(p->z[perGene]) * tr->fracchanges[perGene]; |
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503 | rz = exp(-(z * 0.5)/ tr->fracchanges[perGene]); |
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504 | p->z[perGene] = p->back->z[perGene] = rz; |
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505 | } |
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506 | } |
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507 | } |
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508 | } |
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509 | |
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510 | *treestr = '('; |
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511 | treestr++; |
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512 | treestr = rootedTreeREC(treestr, tr, p, printBranchLengths, printNames, printLikelihood, rellTree, finalPrint, |
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513 | adef, perGene, branchLabelSupport, printSHSupport); |
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514 | *treestr = ','; |
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515 | treestr++; |
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516 | treestr = rootedTreeREC(treestr, tr, p->back, printBranchLengths, printNames, printLikelihood, rellTree, finalPrint, |
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517 | adef, perGene, branchLabelSupport, printSHSupport); |
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518 | sprintf(treestr, ");\n"); |
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519 | while (*treestr) treestr++; |
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520 | |
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521 | |
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522 | for(int i = 0; i < tr->numBranches; i++) |
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523 | p->z[i] = p->back->z[i] = oldz[i]; |
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524 | |
---|
525 | return treestr; |
---|
526 | } |
---|
527 | |
---|
528 | |
---|
529 | |
---|
530 | char *Tree2String(char *treestr, tree *tr, nodeptr p, boolean printBranchLengths, boolean printNames, boolean printLikelihood, |
---|
531 | boolean rellTree, |
---|
532 | boolean finalPrint, analdef *adef, int perGene, boolean branchLabelSupport, boolean printSHSupport, boolean printIC, boolean printSHSupports) |
---|
533 | { |
---|
534 | |
---|
535 | if(rellTree) |
---|
536 | assert(!branchLabelSupport && !printSHSupport); |
---|
537 | |
---|
538 | if(branchLabelSupport) |
---|
539 | assert(!rellTree && !printSHSupport); |
---|
540 | |
---|
541 | if(printSHSupport) |
---|
542 | assert(!branchLabelSupport && !rellTree); |
---|
543 | |
---|
544 | if(finalPrint && adef->outgroup) |
---|
545 | { |
---|
546 | nodeptr startNode = tr->start; |
---|
547 | |
---|
548 | if(tr->numberOfOutgroups > 1) |
---|
549 | { |
---|
550 | nodeptr root; |
---|
551 | nodeptr *subtrees = (nodeptr *)rax_malloc(sizeof(nodeptr) * tr->mxtips); |
---|
552 | int i, k, count = 0; |
---|
553 | int *nodeNumbers = (int*)rax_malloc(sizeof(int) * tr->numberOfOutgroups); |
---|
554 | int *foundVector = (int*)rax_malloc(sizeof(int) * tr->numberOfOutgroups); |
---|
555 | boolean monophyletic = FALSE; |
---|
556 | |
---|
557 | collectSubtrees(tr, subtrees, &count, tr->numberOfOutgroups); |
---|
558 | |
---|
559 | /*printf("Found %d subtrees of size %d\n", count, tr->numberOfOutgroups);*/ |
---|
560 | |
---|
561 | for(i = 0; (i < count) && (!monophyletic); i++) |
---|
562 | { |
---|
563 | int l, sum, nc = 0; |
---|
564 | for(k = 0; k < tr->numberOfOutgroups; k++) |
---|
565 | { |
---|
566 | nodeNumbers[k] = -1; |
---|
567 | foundVector[k] = 0; |
---|
568 | } |
---|
569 | |
---|
570 | checkOM(subtrees[i], nodeNumbers, &nc, tr); |
---|
571 | |
---|
572 | for(l = 0; l < tr->numberOfOutgroups; l++) |
---|
573 | for(k = 0; k < tr->numberOfOutgroups; k++) |
---|
574 | { |
---|
575 | if(nodeNumbers[l] == tr->outgroupNums[k]) |
---|
576 | foundVector[l] = 1; |
---|
577 | } |
---|
578 | |
---|
579 | sum = 0; |
---|
580 | for(l = 0; l < tr->numberOfOutgroups; l++) |
---|
581 | sum += foundVector[l]; |
---|
582 | |
---|
583 | if(sum == tr->numberOfOutgroups) |
---|
584 | { |
---|
585 | root = subtrees[i]; |
---|
586 | tr->start = root; |
---|
587 | /*printf("outgroups are monphyletic!\n");*/ |
---|
588 | monophyletic = TRUE; |
---|
589 | } |
---|
590 | else |
---|
591 | { |
---|
592 | if(sum > 0) |
---|
593 | { |
---|
594 | /*printf("outgroups are NOT monophyletic!\n");*/ |
---|
595 | monophyletic = FALSE; |
---|
596 | } |
---|
597 | } |
---|
598 | } |
---|
599 | |
---|
600 | if(!monophyletic) |
---|
601 | { |
---|
602 | printf("WARNING, outgroups are not monophyletic, using first outgroup \"%s\"\n", tr->nameList[tr->outgroupNums[0]]); |
---|
603 | printf("from the list to root the tree!\n"); |
---|
604 | |
---|
605 | |
---|
606 | { |
---|
607 | FILE *infoFile = myfopen(infoFileName, "ab"); |
---|
608 | |
---|
609 | fprintf(infoFile, "\nWARNING, outgroups are not monophyletic, using first outgroup \"%s\"\n", tr->nameList[tr->outgroupNums[0]]); |
---|
610 | fprintf(infoFile, "from the list to root the tree!\n"); |
---|
611 | |
---|
612 | fclose(infoFile); |
---|
613 | } |
---|
614 | |
---|
615 | |
---|
616 | tr->start = tr->nodep[tr->outgroupNums[0]]; |
---|
617 | |
---|
618 | rootedTree(treestr, tr, tr->start->back, printBranchLengths, printNames, printLikelihood, rellTree, |
---|
619 | finalPrint, adef, perGene, branchLabelSupport, printSHSupport); |
---|
620 | } |
---|
621 | else |
---|
622 | { |
---|
623 | if(isTip(tr->start->number, tr->rdta->numsp)) |
---|
624 | { |
---|
625 | printf("Outgroup-Monophyly ERROR; tr->start is a tip \n"); |
---|
626 | errorExit(-1); |
---|
627 | } |
---|
628 | if(isTip(tr->start->back->number, tr->rdta->numsp)) |
---|
629 | { |
---|
630 | printf("Outgroup-Monophyly ERROR; tr->start is a tip \n"); |
---|
631 | errorExit(-1); |
---|
632 | } |
---|
633 | |
---|
634 | rootedTree(treestr, tr, tr->start->back, printBranchLengths, printNames, printLikelihood, rellTree, |
---|
635 | finalPrint, adef, perGene, branchLabelSupport, printSHSupport); |
---|
636 | } |
---|
637 | |
---|
638 | rax_free(foundVector); |
---|
639 | rax_free(nodeNumbers); |
---|
640 | rax_free(subtrees); |
---|
641 | } |
---|
642 | else |
---|
643 | { |
---|
644 | tr->start = tr->nodep[tr->outgroupNums[0]]; |
---|
645 | rootedTree(treestr, tr, tr->start->back, printBranchLengths, printNames, printLikelihood, rellTree, |
---|
646 | finalPrint, adef, perGene, branchLabelSupport, printSHSupports); |
---|
647 | } |
---|
648 | |
---|
649 | tr->start = startNode; |
---|
650 | } |
---|
651 | else |
---|
652 | Tree2StringREC(treestr, tr, p, printBranchLengths, printNames, printLikelihood, rellTree, |
---|
653 | finalPrint, perGene, branchLabelSupport, printSHSupport, printIC, printSHSupports); |
---|
654 | |
---|
655 | |
---|
656 | while (*treestr) treestr++; |
---|
657 | |
---|
658 | return treestr; |
---|
659 | } |
---|
660 | |
---|
661 | |
---|
662 | void printTreePerGene(tree *tr, analdef *adef, const char *fileName, const char *permission) |
---|
663 | { |
---|
664 | FILE *treeFile; |
---|
665 | char extendedTreeFileName[1024]; |
---|
666 | char buf[16]; |
---|
667 | int i; |
---|
668 | |
---|
669 | assert(adef->perGeneBranchLengths); |
---|
670 | |
---|
671 | for(i = 0; i < tr->numBranches; i++) |
---|
672 | { |
---|
673 | strcpy(extendedTreeFileName, fileName); |
---|
674 | sprintf(buf,"%d", i); |
---|
675 | strcat(extendedTreeFileName, ".PARTITION."); |
---|
676 | strcat(extendedTreeFileName, buf); |
---|
677 | /*printf("Partitiuon %d file %s\n", i, extendedTreeFileName);*/ |
---|
678 | Tree2String(tr->tree_string, tr, tr->start->back, TRUE, TRUE, FALSE, FALSE, TRUE, adef, i, FALSE, FALSE, FALSE, FALSE); |
---|
679 | treeFile = myfopen(extendedTreeFileName, permission); |
---|
680 | fprintf(treeFile, "%s", tr->tree_string); |
---|
681 | fclose(treeFile); |
---|
682 | } |
---|
683 | |
---|
684 | } |
---|
685 | |
---|
686 | |
---|
687 | |
---|
688 | /*=======================================================================*/ |
---|
689 | /* Read a tree from a file */ |
---|
690 | /*=======================================================================*/ |
---|
691 | |
---|
692 | |
---|
693 | /* 1.0.A Processing of quotation marks in comment removed |
---|
694 | */ |
---|
695 | |
---|
696 | static int treeFinishCom (FILE *fp, char **strp) |
---|
697 | { |
---|
698 | int ch; |
---|
699 | |
---|
700 | while ((ch = getc(fp)) != EOF && ch != ']') { |
---|
701 | if (strp != NULL) *(*strp)++ = ch; /* save character */ |
---|
702 | if (ch == '[') { /* nested comment; find its end */ |
---|
703 | if ((ch = treeFinishCom(fp, strp)) == EOF) break; |
---|
704 | if (strp != NULL) *(*strp)++ = ch; /* save closing ] */ |
---|
705 | } |
---|
706 | } |
---|
707 | |
---|
708 | if (strp != NULL) **strp = '\0'; /* terminate string */ |
---|
709 | return ch; |
---|
710 | } /* treeFinishCom */ |
---|
711 | |
---|
712 | |
---|
713 | static int treeGetCh (FILE *fp) /* get next nonblank, noncomment character */ |
---|
714 | { /* treeGetCh */ |
---|
715 | int ch; |
---|
716 | |
---|
717 | while ((ch = getc(fp)) != EOF) { |
---|
718 | if (whitechar(ch)) ; |
---|
719 | else if (ch == '[') { /* comment; find its end */ |
---|
720 | if ((ch = treeFinishCom(fp, (char **) NULL)) == EOF) break; |
---|
721 | } |
---|
722 | else break; |
---|
723 | } |
---|
724 | |
---|
725 | return ch; |
---|
726 | } /* treeGetCh */ |
---|
727 | |
---|
728 | |
---|
729 | static boolean treeLabelEnd (int ch) |
---|
730 | { |
---|
731 | switch (ch) |
---|
732 | { |
---|
733 | case EOF: |
---|
734 | case '\0': |
---|
735 | case '\t': |
---|
736 | case '\n': |
---|
737 | case '\r': |
---|
738 | case ' ': |
---|
739 | case ':': |
---|
740 | case ',': |
---|
741 | case '(': |
---|
742 | case ')': |
---|
743 | case ';': |
---|
744 | return TRUE; |
---|
745 | default: |
---|
746 | break; |
---|
747 | } |
---|
748 | return FALSE; |
---|
749 | } |
---|
750 | |
---|
751 | |
---|
752 | static boolean treeGetLabel (FILE *fp, char *lblPtr, int maxlen) |
---|
753 | { |
---|
754 | int ch; |
---|
755 | boolean done, quoted, lblfound; |
---|
756 | |
---|
757 | if (--maxlen < 0) |
---|
758 | lblPtr = (char *) NULL; |
---|
759 | else |
---|
760 | if (lblPtr == NULL) |
---|
761 | maxlen = 0; |
---|
762 | |
---|
763 | ch = getc(fp); |
---|
764 | done = treeLabelEnd(ch); |
---|
765 | |
---|
766 | lblfound = ! done; |
---|
767 | quoted = (ch == '\''); |
---|
768 | if (quoted && ! done) |
---|
769 | { |
---|
770 | ch = getc(fp); |
---|
771 | done = (ch == EOF); |
---|
772 | } |
---|
773 | |
---|
774 | while (! done) |
---|
775 | { |
---|
776 | if (quoted) |
---|
777 | { |
---|
778 | if (ch == '\'') |
---|
779 | { |
---|
780 | ch = getc(fp); |
---|
781 | if (ch != '\'') |
---|
782 | break; |
---|
783 | } |
---|
784 | } |
---|
785 | else |
---|
786 | if (treeLabelEnd(ch)) break; |
---|
787 | |
---|
788 | if (--maxlen >= 0) *lblPtr++ = ch; |
---|
789 | ch = getc(fp); |
---|
790 | if (ch == EOF) break; |
---|
791 | } |
---|
792 | |
---|
793 | if (ch != EOF) (void) ungetc(ch, fp); |
---|
794 | |
---|
795 | if (lblPtr != NULL) *lblPtr = '\0'; |
---|
796 | |
---|
797 | return lblfound; |
---|
798 | } |
---|
799 | |
---|
800 | |
---|
801 | static boolean treeFlushLabel (FILE *fp) |
---|
802 | { |
---|
803 | return treeGetLabel(fp, (char *) NULL, (int) 0); |
---|
804 | } |
---|
805 | |
---|
806 | |
---|
807 | |
---|
808 | |
---|
809 | static int treeFindTipByLabelString(char *str, tree *tr, boolean check) |
---|
810 | { |
---|
811 | int |
---|
812 | lookup = lookupWord(str, tr->nameHash); |
---|
813 | |
---|
814 | if(lookup > 0) |
---|
815 | { |
---|
816 | if(check) |
---|
817 | assert(! tr->nodep[lookup]->back); |
---|
818 | return lookup; |
---|
819 | } |
---|
820 | else |
---|
821 | { |
---|
822 | printf("ERROR: Cannot find tree species: %s\n", str); |
---|
823 | return 0; |
---|
824 | } |
---|
825 | } |
---|
826 | |
---|
827 | |
---|
828 | int treeFindTipName(FILE *fp, tree *tr, boolean check) |
---|
829 | { |
---|
830 | char str[nmlngth+2]; |
---|
831 | int n; |
---|
832 | |
---|
833 | if(treeGetLabel(fp, str, nmlngth+2)) |
---|
834 | n = treeFindTipByLabelString(str, tr, check); |
---|
835 | else |
---|
836 | n = 0; |
---|
837 | |
---|
838 | |
---|
839 | return n; |
---|
840 | } |
---|
841 | |
---|
842 | |
---|
843 | |
---|
844 | static void treeEchoContext (FILE *fp1, FILE *fp2, int n) |
---|
845 | { /* treeEchoContext */ |
---|
846 | int ch; |
---|
847 | boolean waswhite; |
---|
848 | |
---|
849 | waswhite = TRUE; |
---|
850 | |
---|
851 | while (n > 0 && ((ch = getc(fp1)) != EOF)) { |
---|
852 | if (whitechar(ch)) { |
---|
853 | ch = waswhite ? '\0' : ' '; |
---|
854 | waswhite = TRUE; |
---|
855 | } |
---|
856 | else { |
---|
857 | waswhite = FALSE; |
---|
858 | } |
---|
859 | |
---|
860 | if (ch > '\0') {putc(ch, fp2); n--;} |
---|
861 | } |
---|
862 | } /* treeEchoContext */ |
---|
863 | |
---|
864 | static boolean treeNeedCh (FILE *fp, int c1, const char *where); |
---|
865 | |
---|
866 | |
---|
867 | static boolean treeProcessLength (FILE *fp, double *dptr, int *branchLabel, boolean storeBranchLabels, tree *tr) |
---|
868 | { |
---|
869 | int |
---|
870 | ch; |
---|
871 | |
---|
872 | if((ch = treeGetCh(fp)) == EOF) |
---|
873 | return FALSE; /* Skip comments */ |
---|
874 | (void) ungetc(ch, fp); |
---|
875 | |
---|
876 | if(fscanf(fp, "%lf", dptr) != 1) |
---|
877 | { |
---|
878 | printf("ERROR: treeProcessLength: Problem reading branch length\n"); |
---|
879 | treeEchoContext(fp, stdout, 40); |
---|
880 | printf("\n"); |
---|
881 | return FALSE; |
---|
882 | } |
---|
883 | |
---|
884 | if((ch = getc(fp)) != EOF) |
---|
885 | { |
---|
886 | if(ch == '[') |
---|
887 | { |
---|
888 | if(fscanf(fp, "%d", branchLabel) != 1) |
---|
889 | goto handleError; |
---|
890 | |
---|
891 | //printf("Branch label: %d\n", *branchLabel); |
---|
892 | |
---|
893 | if((ch = getc(fp)) != ']') |
---|
894 | { |
---|
895 | handleError: |
---|
896 | printf("ERROR: treeProcessLength: Problem reading branch label\n"); |
---|
897 | treeEchoContext(fp, stdout, 40); |
---|
898 | printf("\n"); |
---|
899 | return FALSE; |
---|
900 | } |
---|
901 | |
---|
902 | if(storeBranchLabels) |
---|
903 | tr->branchLabelCounter = tr->branchLabelCounter + 1; |
---|
904 | |
---|
905 | } |
---|
906 | else |
---|
907 | (void)ungetc(ch, fp); |
---|
908 | } |
---|
909 | |
---|
910 | return TRUE; |
---|
911 | } |
---|
912 | |
---|
913 | |
---|
914 | static int treeFlushLen (FILE *fp, tree *tr) |
---|
915 | { |
---|
916 | double |
---|
917 | dummy; |
---|
918 | int |
---|
919 | dummyLabel, |
---|
920 | ch; |
---|
921 | |
---|
922 | ch = treeGetCh(fp); |
---|
923 | |
---|
924 | if (ch == ':') |
---|
925 | { |
---|
926 | ch = treeGetCh(fp); |
---|
927 | |
---|
928 | ungetc(ch, fp); |
---|
929 | if(!treeProcessLength(fp, &dummy, &dummyLabel, FALSE, tr)) |
---|
930 | return 0; |
---|
931 | return 1; |
---|
932 | } |
---|
933 | |
---|
934 | |
---|
935 | |
---|
936 | if (ch != EOF) (void) ungetc(ch, fp); |
---|
937 | return 1; |
---|
938 | } |
---|
939 | |
---|
940 | |
---|
941 | |
---|
942 | |
---|
943 | |
---|
944 | static boolean treeNeedCh (FILE *fp, int c1, const char *where) |
---|
945 | { |
---|
946 | int c2; |
---|
947 | |
---|
948 | if ((c2 = treeGetCh(fp)) == c1) return TRUE; |
---|
949 | |
---|
950 | printf("ERROR: Expecting '%c' %s tree; found:", c1, where); |
---|
951 | if (c2 == EOF) |
---|
952 | { |
---|
953 | printf("End-of-File"); |
---|
954 | } |
---|
955 | else |
---|
956 | { |
---|
957 | ungetc(c2, fp); |
---|
958 | treeEchoContext(fp, stdout, 40); |
---|
959 | } |
---|
960 | putchar('\n'); |
---|
961 | |
---|
962 | printf("RAxML may be expecting to read a tree that contains branch lengths\n"); |
---|
963 | |
---|
964 | return FALSE; |
---|
965 | } |
---|
966 | |
---|
967 | |
---|
968 | |
---|
969 | static boolean addElementLen (FILE *fp, tree *tr, nodeptr p, boolean readBranchLengths, boolean readNodeLabels, int *lcount, analdef *adef, boolean storeBranchLabels) |
---|
970 | { |
---|
971 | nodeptr q; |
---|
972 | int n, ch, fres; |
---|
973 | |
---|
974 | if ((ch = treeGetCh(fp)) == '(') |
---|
975 | { |
---|
976 | n = (tr->nextnode)++; |
---|
977 | if (n > 2*(tr->mxtips) - 2) |
---|
978 | { |
---|
979 | if (tr->rooted || n > 2*(tr->mxtips) - 1) |
---|
980 | { |
---|
981 | printf("ERROR: Too many internal nodes. Is tree rooted?\n"); |
---|
982 | printf(" Deepest splitting should be a trifurcation.\n"); |
---|
983 | return FALSE; |
---|
984 | } |
---|
985 | else |
---|
986 | { |
---|
987 | if(readNodeLabels) |
---|
988 | { |
---|
989 | printf("The program will exit with an error in the next source code line\n"); |
---|
990 | printf("You are probably trying to read in rooted trees with a RAxML option \n"); |
---|
991 | printf("that for some reason expects unrooted binary trees\n\n"); |
---|
992 | } |
---|
993 | |
---|
994 | assert(!readNodeLabels); |
---|
995 | tr->rooted = TRUE; |
---|
996 | } |
---|
997 | } |
---|
998 | |
---|
999 | q = tr->nodep[n]; |
---|
1000 | |
---|
1001 | if (! addElementLen(fp, tr, q->next, readBranchLengths, readNodeLabels, lcount, adef, storeBranchLabels)) return FALSE; |
---|
1002 | if (! treeNeedCh(fp, ',', "in")) return FALSE; |
---|
1003 | if (! addElementLen(fp, tr, q->next->next, readBranchLengths, readNodeLabels, lcount, adef, storeBranchLabels)) return FALSE; |
---|
1004 | if (! treeNeedCh(fp, ')', "in")) return FALSE; |
---|
1005 | |
---|
1006 | if(readNodeLabels) |
---|
1007 | { |
---|
1008 | char label[64]; |
---|
1009 | int support; |
---|
1010 | |
---|
1011 | if(treeGetLabel (fp, label, 10)) |
---|
1012 | { |
---|
1013 | int val = sscanf(label, "%d", &support); |
---|
1014 | |
---|
1015 | assert(val == 1); |
---|
1016 | |
---|
1017 | /*printf("LABEL %s Number %d\n", label, support);*/ |
---|
1018 | p->support = q->support = support; |
---|
1019 | /*printf("%d %d %d %d\n", p->support, q->support, p->number, q->number);*/ |
---|
1020 | assert(p->number > tr->mxtips && q->number > tr->mxtips); |
---|
1021 | *lcount = *lcount + 1; |
---|
1022 | } |
---|
1023 | } |
---|
1024 | else |
---|
1025 | (void) treeFlushLabel(fp); |
---|
1026 | } |
---|
1027 | else |
---|
1028 | { |
---|
1029 | ungetc(ch, fp); |
---|
1030 | if ((n = treeFindTipName(fp, tr, TRUE)) <= 0) return FALSE; |
---|
1031 | q = tr->nodep[n]; |
---|
1032 | if (tr->start->number > n) tr->start = q; |
---|
1033 | (tr->ntips)++; |
---|
1034 | } |
---|
1035 | |
---|
1036 | if(readBranchLengths) |
---|
1037 | { |
---|
1038 | double |
---|
1039 | branch; |
---|
1040 | |
---|
1041 | int |
---|
1042 | startCounter = tr->branchLabelCounter, |
---|
1043 | endCounter, |
---|
1044 | branchLabel = -1; |
---|
1045 | |
---|
1046 | if (! treeNeedCh(fp, ':', "in")) return FALSE; |
---|
1047 | if (! treeProcessLength(fp, &branch, &branchLabel, storeBranchLabels, tr)) |
---|
1048 | return FALSE; |
---|
1049 | |
---|
1050 | endCounter = tr->branchLabelCounter; |
---|
1051 | |
---|
1052 | /*printf("Branch %8.20f %d\n", branch, tr->numBranches);*/ |
---|
1053 | if(adef->mode == CLASSIFY_ML) |
---|
1054 | { |
---|
1055 | double |
---|
1056 | x[NUM_BRANCHES]; |
---|
1057 | |
---|
1058 | assert(tr->NumberOfModels == 1); |
---|
1059 | assert(adef->useBinaryModelFile); |
---|
1060 | assert(tr->numBranches == 1); |
---|
1061 | |
---|
1062 | x[0] = exp(-branch / tr->fracchange); |
---|
1063 | |
---|
1064 | hookup(p, q, x, tr->numBranches); |
---|
1065 | } |
---|
1066 | else |
---|
1067 | hookup(p, q, &branch, tr->numBranches); |
---|
1068 | |
---|
1069 | if(storeBranchLabels && (endCounter > startCounter)) |
---|
1070 | { |
---|
1071 | assert(!isTip(p->number, tr->mxtips) && !isTip(q->number, tr->mxtips)); |
---|
1072 | assert(branchLabel >= 0); |
---|
1073 | p->support = q->support = branchLabel; |
---|
1074 | } |
---|
1075 | } |
---|
1076 | else |
---|
1077 | { |
---|
1078 | fres = treeFlushLen(fp, tr); |
---|
1079 | if(!fres) return FALSE; |
---|
1080 | |
---|
1081 | hookupDefault(p, q, tr->numBranches); |
---|
1082 | } |
---|
1083 | return TRUE; |
---|
1084 | } |
---|
1085 | |
---|
1086 | |
---|
1087 | |
---|
1088 | |
---|
1089 | |
---|
1090 | |
---|
1091 | |
---|
1092 | |
---|
1093 | |
---|
1094 | |
---|
1095 | |
---|
1096 | static nodeptr uprootTree (tree *tr, nodeptr p, boolean readBranchLengths, boolean readConstraint) |
---|
1097 | { |
---|
1098 | nodeptr q, r, s, start; |
---|
1099 | int n; |
---|
1100 | |
---|
1101 | for(int i = tr->mxtips + 1; i < 2 * tr->mxtips - 1; i++) |
---|
1102 | assert(i == tr->nodep[i]->number); |
---|
1103 | |
---|
1104 | |
---|
1105 | |
---|
1106 | |
---|
1107 | if(isTip(p->number, tr->mxtips) || p->back) |
---|
1108 | { |
---|
1109 | printf("ERROR: Unable to uproot tree.\n"); |
---|
1110 | printf(" Inappropriate node marked for removal.\n"); |
---|
1111 | assert(0); |
---|
1112 | } |
---|
1113 | |
---|
1114 | assert(p->back == (nodeptr)NULL); |
---|
1115 | |
---|
1116 | tr->nextnode = tr->nextnode - 1; |
---|
1117 | |
---|
1118 | assert(tr->nextnode < 2 * tr->mxtips); |
---|
1119 | |
---|
1120 | n = tr->nextnode; |
---|
1121 | |
---|
1122 | assert(tr->nodep[tr->nextnode]); |
---|
1123 | |
---|
1124 | if (n != tr->mxtips + tr->ntips - 1) |
---|
1125 | { |
---|
1126 | printf("ERROR: Unable to uproot tree. Inconsistent\n"); |
---|
1127 | printf(" number of tips and nodes for rooted tree.\n"); |
---|
1128 | assert(0); |
---|
1129 | } |
---|
1130 | |
---|
1131 | q = p->next->back; /* remove p from tree */ |
---|
1132 | r = p->next->next->back; |
---|
1133 | assert(p->back == (nodeptr)NULL); |
---|
1134 | |
---|
1135 | if(readBranchLengths) |
---|
1136 | { |
---|
1137 | double b[NUM_BRANCHES]; |
---|
1138 | for(int i = 0; i < tr->numBranches; i++) |
---|
1139 | { |
---|
1140 | b[i] = (r->z[i] + q->z[i]); |
---|
1141 | } |
---|
1142 | hookup (q, r, b, tr->numBranches); |
---|
1143 | } |
---|
1144 | else |
---|
1145 | hookupDefault(q, r, tr->numBranches); |
---|
1146 | |
---|
1147 | tr->leftRootNode = p->next->back; |
---|
1148 | tr->rightRootNode = p->next->next->back; |
---|
1149 | |
---|
1150 | if(readConstraint && tr->grouped) |
---|
1151 | { |
---|
1152 | if(tr->constraintVector[p->number] != 0) |
---|
1153 | { |
---|
1154 | printf("Root node to remove should have top-level grouping of 0\n"); |
---|
1155 | assert(0); |
---|
1156 | } |
---|
1157 | } |
---|
1158 | |
---|
1159 | assert(!(isTip(r->number, tr->mxtips) && isTip(q->number, tr->mxtips))); |
---|
1160 | |
---|
1161 | assert(p->number > tr->mxtips); |
---|
1162 | |
---|
1163 | if(tr->ntips > 2 && p->number != n) |
---|
1164 | { |
---|
1165 | q = tr->nodep[n]; /* transfer last node's conections to p */ |
---|
1166 | r = q->next; |
---|
1167 | s = q->next->next; |
---|
1168 | |
---|
1169 | if(readConstraint && tr->grouped) |
---|
1170 | tr->constraintVector[p->number] = tr->constraintVector[q->number]; |
---|
1171 | |
---|
1172 | hookup(p, q->back, q->z, tr->numBranches); /* move connections to p */ |
---|
1173 | hookup(p->next, r->back, r->z, tr->numBranches); |
---|
1174 | hookup(p->next->next, s->back, s->z, tr->numBranches); |
---|
1175 | |
---|
1176 | if(q == tr->leftRootNode || q == tr->rightRootNode) |
---|
1177 | { |
---|
1178 | if(q == tr->leftRootNode) |
---|
1179 | { |
---|
1180 | if(p->back == tr->rightRootNode) |
---|
1181 | tr->leftRootNode = p; |
---|
1182 | else |
---|
1183 | { |
---|
1184 | if(p->next->back == tr->rightRootNode) |
---|
1185 | tr->leftRootNode = p->next; |
---|
1186 | else |
---|
1187 | { |
---|
1188 | if(p->next->next->back == tr->rightRootNode) |
---|
1189 | tr->leftRootNode = p->next->next; |
---|
1190 | else |
---|
1191 | assert(0); |
---|
1192 | } |
---|
1193 | } |
---|
1194 | } |
---|
1195 | else |
---|
1196 | { |
---|
1197 | assert(q == tr->rightRootNode); |
---|
1198 | |
---|
1199 | if(p->back == tr->leftRootNode) |
---|
1200 | tr->rightRootNode = p; |
---|
1201 | else |
---|
1202 | { |
---|
1203 | if(p->next->back == tr->leftRootNode) |
---|
1204 | tr->rightRootNode = p->next; |
---|
1205 | else |
---|
1206 | { |
---|
1207 | if(p->next->next->back == tr->leftRootNode) |
---|
1208 | tr->rightRootNode = p->next->next; |
---|
1209 | else |
---|
1210 | assert(0); |
---|
1211 | } |
---|
1212 | } |
---|
1213 | } |
---|
1214 | } |
---|
1215 | |
---|
1216 | q->back = q->next->back = q->next->next->back = (nodeptr) NULL; |
---|
1217 | } |
---|
1218 | else |
---|
1219 | { |
---|
1220 | assert(tr->ntips > 2); |
---|
1221 | p->back = p->next->back = p->next->next->back = (nodeptr) NULL; |
---|
1222 | } |
---|
1223 | |
---|
1224 | |
---|
1225 | |
---|
1226 | assert(tr->ntips > 2); |
---|
1227 | |
---|
1228 | start = findAnyTip(tr->nodep[tr->mxtips + 1], tr->mxtips); |
---|
1229 | |
---|
1230 | assert(isTip(start->number, tr->mxtips)); |
---|
1231 | tr->rooted = FALSE; |
---|
1232 | return start; |
---|
1233 | } |
---|
1234 | |
---|
1235 | |
---|
1236 | int treeReadLen (FILE *fp, tree *tr, boolean readBranches, boolean readNodeLabels, boolean topologyOnly, analdef *adef, boolean completeTree, boolean storeBranchLabels) |
---|
1237 | { |
---|
1238 | nodeptr |
---|
1239 | p; |
---|
1240 | |
---|
1241 | int |
---|
1242 | i, |
---|
1243 | ch, |
---|
1244 | lcount = 0; |
---|
1245 | |
---|
1246 | tr->branchLabelCounter = 0; |
---|
1247 | |
---|
1248 | for (i = 1; i <= tr->mxtips; i++) |
---|
1249 | { |
---|
1250 | tr->nodep[i]->back = (node *) NULL; |
---|
1251 | if(topologyOnly) |
---|
1252 | tr->nodep[i]->support = -1; |
---|
1253 | } |
---|
1254 | |
---|
1255 | for(i = tr->mxtips + 1; i < 2 * tr->mxtips; i++) |
---|
1256 | { |
---|
1257 | tr->nodep[i]->back = (nodeptr)NULL; |
---|
1258 | tr->nodep[i]->next->back = (nodeptr)NULL; |
---|
1259 | tr->nodep[i]->next->next->back = (nodeptr)NULL; |
---|
1260 | tr->nodep[i]->number = i; |
---|
1261 | tr->nodep[i]->next->number = i; |
---|
1262 | tr->nodep[i]->next->next->number = i; |
---|
1263 | |
---|
1264 | if(topologyOnly) |
---|
1265 | { |
---|
1266 | tr->nodep[i]->support = -2; |
---|
1267 | tr->nodep[i]->next->support = -2; |
---|
1268 | tr->nodep[i]->next->next->support = -2; |
---|
1269 | } |
---|
1270 | } |
---|
1271 | |
---|
1272 | if(topologyOnly) |
---|
1273 | tr->start = tr->nodep[tr->mxtips]; |
---|
1274 | else |
---|
1275 | tr->start = tr->nodep[1]; |
---|
1276 | |
---|
1277 | tr->ntips = 0; |
---|
1278 | tr->nextnode = tr->mxtips + 1; |
---|
1279 | |
---|
1280 | for(i = 0; i < tr->numBranches; i++) |
---|
1281 | tr->partitionSmoothed[i] = FALSE; |
---|
1282 | |
---|
1283 | tr->rooted = FALSE; |
---|
1284 | tr->wasRooted = FALSE; |
---|
1285 | |
---|
1286 | p = tr->nodep[(tr->nextnode)++]; |
---|
1287 | |
---|
1288 | while((ch = treeGetCh(fp)) != '('); |
---|
1289 | |
---|
1290 | if(!topologyOnly) |
---|
1291 | { |
---|
1292 | if(adef->mode != CLASSIFY_ML) |
---|
1293 | { |
---|
1294 | if(adef->mode != OPTIMIZE_BR_LEN_SCALER) |
---|
1295 | assert(readBranches == FALSE && readNodeLabels == FALSE); |
---|
1296 | else |
---|
1297 | assert(readBranches == TRUE && readNodeLabels == FALSE); |
---|
1298 | } |
---|
1299 | else |
---|
1300 | { |
---|
1301 | if(adef->useBinaryModelFile) |
---|
1302 | assert(readBranches == TRUE && readNodeLabels == FALSE); |
---|
1303 | else |
---|
1304 | assert(readBranches == FALSE && readNodeLabels == FALSE); |
---|
1305 | } |
---|
1306 | } |
---|
1307 | |
---|
1308 | |
---|
1309 | if (! addElementLen(fp, tr, p, readBranches, readNodeLabels, &lcount, adef, storeBranchLabels)) |
---|
1310 | assert(0); |
---|
1311 | if (! treeNeedCh(fp, ',', "in")) |
---|
1312 | assert(0); |
---|
1313 | if (! addElementLen(fp, tr, p->next, readBranches, readNodeLabels, &lcount, adef, storeBranchLabels)) |
---|
1314 | assert(0); |
---|
1315 | if (! tr->rooted) |
---|
1316 | { |
---|
1317 | if ((ch = treeGetCh(fp)) == ',') |
---|
1318 | { |
---|
1319 | if (! addElementLen(fp, tr, p->next->next, readBranches, readNodeLabels, &lcount, adef, storeBranchLabels)) |
---|
1320 | assert(0); |
---|
1321 | } |
---|
1322 | else |
---|
1323 | { |
---|
1324 | /* A rooted format */ |
---|
1325 | |
---|
1326 | tr->rooted = TRUE; |
---|
1327 | tr->wasRooted = TRUE; |
---|
1328 | |
---|
1329 | if (ch != EOF) (void) ungetc(ch, fp); |
---|
1330 | } |
---|
1331 | } |
---|
1332 | else |
---|
1333 | { |
---|
1334 | p->next->next->back = (nodeptr) NULL; |
---|
1335 | tr->wasRooted = TRUE; |
---|
1336 | } |
---|
1337 | |
---|
1338 | if(!tr->rooted && adef->mode == ANCESTRAL_STATES) |
---|
1339 | { |
---|
1340 | printf("Error: The ancestral state computation mode requires a rooted tree as input, exiting ....\n"); |
---|
1341 | exit(0); |
---|
1342 | } |
---|
1343 | |
---|
1344 | if (! treeNeedCh(fp, ')', "in")) |
---|
1345 | assert(0); |
---|
1346 | |
---|
1347 | if(topologyOnly) |
---|
1348 | assert(!(tr->rooted && readNodeLabels)); |
---|
1349 | |
---|
1350 | (void) treeFlushLabel(fp); |
---|
1351 | |
---|
1352 | if (! treeFlushLen(fp, tr)) |
---|
1353 | assert(0); |
---|
1354 | |
---|
1355 | if (! treeNeedCh(fp, ';', "at end of")) |
---|
1356 | assert(0); |
---|
1357 | |
---|
1358 | if (tr->rooted) |
---|
1359 | { |
---|
1360 | assert(!readNodeLabels); |
---|
1361 | |
---|
1362 | p->next->next->back = (nodeptr) NULL; |
---|
1363 | tr->start = uprootTree(tr, p->next->next, readBranches, FALSE); |
---|
1364 | |
---|
1365 | |
---|
1366 | /*tr->leftRootNode = p->back; |
---|
1367 | tr->rightRootNode = p->next->back; |
---|
1368 | */ |
---|
1369 | |
---|
1370 | if (! tr->start) |
---|
1371 | { |
---|
1372 | printf("FATAL ERROR UPROOTING TREE\n"); |
---|
1373 | assert(0); |
---|
1374 | } |
---|
1375 | } |
---|
1376 | else |
---|
1377 | tr->start = findAnyTip(p, tr->rdta->numsp); |
---|
1378 | |
---|
1379 | if(!topologyOnly || adef->mode == CLASSIFY_MP) |
---|
1380 | { |
---|
1381 | assert(tr->ntips <= tr->mxtips); |
---|
1382 | |
---|
1383 | |
---|
1384 | if(tr->ntips < tr->mxtips) |
---|
1385 | { |
---|
1386 | if(completeTree) |
---|
1387 | { |
---|
1388 | printBothOpen("Hello this is your friendly RAxML tree parsing routine\n"); |
---|
1389 | printBothOpen("The RAxML option you are uisng requires to read in only complete trees\n"); |
---|
1390 | printBothOpen("with %d taxa, there is at least one tree with %d taxa though ... exiting\n", tr->mxtips, tr->ntips); |
---|
1391 | exit(-1); |
---|
1392 | } |
---|
1393 | else |
---|
1394 | { |
---|
1395 | if(adef->computeDistance) |
---|
1396 | { |
---|
1397 | printBothOpen("Error: pairwise distance computation only allows for complete, i.e., containing all taxa\n"); |
---|
1398 | printBothOpen("bifurcating starting trees\n"); |
---|
1399 | exit(-1); |
---|
1400 | } |
---|
1401 | if(adef->mode == CLASSIFY_ML || adef->mode == CLASSIFY_MP) |
---|
1402 | { |
---|
1403 | printBothOpen("RAxML placement algorithm: You provided a reference tree with %d taxa; alignmnet has %d taxa\n", tr->ntips, tr->mxtips); |
---|
1404 | printBothOpen("%d query taxa will be placed using %s\n", tr->mxtips - tr->ntips, (adef->mode == CLASSIFY_ML)?"maximum likelihood":"parsimony"); |
---|
1405 | if(adef->mode == CLASSIFY_ML) |
---|
1406 | classifyML(tr, adef); |
---|
1407 | else |
---|
1408 | { |
---|
1409 | assert(adef->mode == CLASSIFY_MP); |
---|
1410 | classifyMP(tr, adef); |
---|
1411 | } |
---|
1412 | } |
---|
1413 | else |
---|
1414 | { |
---|
1415 | printBothOpen("You provided an incomplete starting tree %d alignmnet has %d taxa\n", tr->ntips, tr->mxtips); |
---|
1416 | makeParsimonyTreeIncomplete(tr, adef); |
---|
1417 | } |
---|
1418 | } |
---|
1419 | } |
---|
1420 | else |
---|
1421 | { |
---|
1422 | if(adef->mode == PARSIMONY_ADDITION) |
---|
1423 | { |
---|
1424 | printBothOpen("Error you want to add sequences to a trees via MP stepwise addition, but \n"); |
---|
1425 | printBothOpen("you have provided an input tree that already contains all taxa\n"); |
---|
1426 | exit(-1); |
---|
1427 | } |
---|
1428 | if(adef->mode == CLASSIFY_ML || adef->mode == CLASSIFY_MP) |
---|
1429 | { |
---|
1430 | printBothOpen("Error you want to place query sequences into a tree using %s, but\n", tr->mxtips - tr->ntips, (adef->mode == CLASSIFY_ML)?"maximum likelihood":"parsimony"); |
---|
1431 | printBothOpen("you have provided an input tree that already contains all taxa\n"); |
---|
1432 | exit(-1); |
---|
1433 | } |
---|
1434 | } |
---|
1435 | |
---|
1436 | onlyInitrav(tr, tr->start); |
---|
1437 | } |
---|
1438 | |
---|
1439 | |
---|
1440 | return lcount; |
---|
1441 | } |
---|
1442 | |
---|
1443 | |
---|
1444 | |
---|
1445 | /********************************MULTIFURCATIONS************************************************/ |
---|
1446 | |
---|
1447 | |
---|
1448 | static boolean addElementLenMULT (FILE *fp, tree *tr, nodeptr p, int partitionCounter) |
---|
1449 | { |
---|
1450 | nodeptr q, r, s; |
---|
1451 | int n, ch, fres, rn; |
---|
1452 | double randomResolution; |
---|
1453 | int old; |
---|
1454 | |
---|
1455 | tr->constraintVector[p->number] = partitionCounter; |
---|
1456 | |
---|
1457 | if ((ch = treeGetCh(fp)) == '(') |
---|
1458 | { |
---|
1459 | partCount++; |
---|
1460 | old = partCount; |
---|
1461 | |
---|
1462 | n = (tr->nextnode)++; |
---|
1463 | if (n > 2*(tr->mxtips) - 2) |
---|
1464 | { |
---|
1465 | if (tr->rooted || n > 2*(tr->mxtips) - 1) |
---|
1466 | { |
---|
1467 | printf("ERROR: Too many internal nodes. Is tree rooted?\n"); |
---|
1468 | printf(" Deepest splitting should be a trifurcation.\n"); |
---|
1469 | return FALSE; |
---|
1470 | } |
---|
1471 | else |
---|
1472 | { |
---|
1473 | tr->rooted = TRUE; |
---|
1474 | } |
---|
1475 | } |
---|
1476 | q = tr->nodep[n]; |
---|
1477 | tr->constraintVector[q->number] = partCount; |
---|
1478 | if (! addElementLenMULT(fp, tr, q->next, old)) return FALSE; |
---|
1479 | if (! treeNeedCh(fp, ',', "in")) return FALSE; |
---|
1480 | if (! addElementLenMULT(fp, tr, q->next->next, old)) return FALSE; |
---|
1481 | |
---|
1482 | hookupDefault(p, q, tr->numBranches); |
---|
1483 | |
---|
1484 | while((ch = treeGetCh(fp)) == ',') |
---|
1485 | { |
---|
1486 | n = (tr->nextnode)++; |
---|
1487 | if (n > 2*(tr->mxtips) - 2) |
---|
1488 | { |
---|
1489 | if (tr->rooted || n > 2*(tr->mxtips) - 1) |
---|
1490 | { |
---|
1491 | printf("ERROR: Too many internal nodes. Is tree rooted?\n"); |
---|
1492 | printf(" Deepest splitting should be a trifurcation.\n"); |
---|
1493 | return FALSE; |
---|
1494 | } |
---|
1495 | else |
---|
1496 | { |
---|
1497 | tr->rooted = TRUE; |
---|
1498 | } |
---|
1499 | } |
---|
1500 | r = tr->nodep[n]; |
---|
1501 | tr->constraintVector[r->number] = partCount; |
---|
1502 | |
---|
1503 | rn = randomInt(10000); |
---|
1504 | if(rn == 0) |
---|
1505 | randomResolution = 0; |
---|
1506 | else |
---|
1507 | randomResolution = ((double)rn)/10000.0; |
---|
1508 | |
---|
1509 | if(randomResolution < 0.5) |
---|
1510 | { |
---|
1511 | s = q->next->back; |
---|
1512 | r->back = q->next; |
---|
1513 | q->next->back = r; |
---|
1514 | r->next->back = s; |
---|
1515 | s->back = r->next; |
---|
1516 | addElementLenMULT(fp, tr, r->next->next, old); |
---|
1517 | } |
---|
1518 | else |
---|
1519 | { |
---|
1520 | s = q->next->next->back; |
---|
1521 | r->back = q->next->next; |
---|
1522 | q->next->next->back = r; |
---|
1523 | r->next->back = s; |
---|
1524 | s->back = r->next; |
---|
1525 | addElementLenMULT(fp, tr, r->next->next, old); |
---|
1526 | } |
---|
1527 | } |
---|
1528 | |
---|
1529 | if(ch != ')') |
---|
1530 | { |
---|
1531 | printf("Missing /) in treeReadLenMULT\n"); |
---|
1532 | exit(-1); |
---|
1533 | } |
---|
1534 | |
---|
1535 | |
---|
1536 | |
---|
1537 | (void) treeFlushLabel(fp); |
---|
1538 | } |
---|
1539 | else |
---|
1540 | { |
---|
1541 | ungetc(ch, fp); |
---|
1542 | if ((n = treeFindTipName(fp, tr, TRUE)) <= 0) return FALSE; |
---|
1543 | q = tr->nodep[n]; |
---|
1544 | tr->constraintVector[q->number] = partitionCounter; |
---|
1545 | |
---|
1546 | if (tr->start->number > n) tr->start = q; |
---|
1547 | (tr->ntips)++; |
---|
1548 | hookupDefault(p, q, tr->numBranches); |
---|
1549 | } |
---|
1550 | |
---|
1551 | fres = treeFlushLen(fp, tr); |
---|
1552 | if(!fres) return FALSE; |
---|
1553 | |
---|
1554 | return TRUE; |
---|
1555 | } |
---|
1556 | |
---|
1557 | |
---|
1558 | |
---|
1559 | |
---|
1560 | |
---|
1561 | boolean treeReadLenMULT (FILE *fp, tree *tr, analdef *adef) |
---|
1562 | { |
---|
1563 | nodeptr p, r, s; |
---|
1564 | int i, ch, n, rn; |
---|
1565 | int partitionCounter = 0; |
---|
1566 | double randomResolution; |
---|
1567 | |
---|
1568 | srand((unsigned int) time(NULL)); |
---|
1569 | |
---|
1570 | for(i = 0; i < 2 * tr->mxtips; i++) |
---|
1571 | tr->constraintVector[i] = -1; |
---|
1572 | |
---|
1573 | for (i = 1; i <= tr->mxtips; i++) |
---|
1574 | tr->nodep[i]->back = (node *) NULL; |
---|
1575 | |
---|
1576 | for(i = tr->mxtips + 1; i < 2 * tr->mxtips; i++) |
---|
1577 | { |
---|
1578 | tr->nodep[i]->back = (nodeptr)NULL; |
---|
1579 | tr->nodep[i]->next->back = (nodeptr)NULL; |
---|
1580 | tr->nodep[i]->next->next->back = (nodeptr)NULL; |
---|
1581 | tr->nodep[i]->number = i; |
---|
1582 | tr->nodep[i]->next->number = i; |
---|
1583 | tr->nodep[i]->next->next->number = i; |
---|
1584 | } |
---|
1585 | |
---|
1586 | |
---|
1587 | tr->start = tr->nodep[tr->mxtips]; |
---|
1588 | tr->ntips = 0; |
---|
1589 | tr->nextnode = tr->mxtips + 1; |
---|
1590 | |
---|
1591 | for(i = 0; i < tr->numBranches; i++) |
---|
1592 | tr->partitionSmoothed[i] = FALSE; |
---|
1593 | |
---|
1594 | tr->rooted = FALSE; |
---|
1595 | |
---|
1596 | p = tr->nodep[(tr->nextnode)++]; |
---|
1597 | while((ch = treeGetCh(fp)) != '('); |
---|
1598 | |
---|
1599 | if (! addElementLenMULT(fp, tr, p, partitionCounter)) return FALSE; |
---|
1600 | if (! treeNeedCh(fp, ',', "in")) return FALSE; |
---|
1601 | if (! addElementLenMULT(fp, tr, p->next, partitionCounter)) return FALSE; |
---|
1602 | if (! tr->rooted) |
---|
1603 | { |
---|
1604 | if ((ch = treeGetCh(fp)) == ',') |
---|
1605 | { |
---|
1606 | if (! addElementLenMULT(fp, tr, p->next->next, partitionCounter)) return FALSE; |
---|
1607 | |
---|
1608 | while((ch = treeGetCh(fp)) == ',') |
---|
1609 | { |
---|
1610 | n = (tr->nextnode)++; |
---|
1611 | assert(n <= 2*(tr->mxtips) - 2); |
---|
1612 | |
---|
1613 | r = tr->nodep[n]; |
---|
1614 | tr->constraintVector[r->number] = partitionCounter; |
---|
1615 | |
---|
1616 | rn = randomInt(10000); |
---|
1617 | if(rn == 0) |
---|
1618 | randomResolution = 0; |
---|
1619 | else |
---|
1620 | randomResolution = ((double)rn)/10000.0; |
---|
1621 | |
---|
1622 | |
---|
1623 | if(randomResolution < 0.5) |
---|
1624 | { |
---|
1625 | s = p->next->next->back; |
---|
1626 | r->back = p->next->next; |
---|
1627 | p->next->next->back = r; |
---|
1628 | r->next->back = s; |
---|
1629 | s->back = r->next; |
---|
1630 | addElementLenMULT(fp, tr, r->next->next, partitionCounter); |
---|
1631 | } |
---|
1632 | else |
---|
1633 | { |
---|
1634 | s = p->next->back; |
---|
1635 | r->back = p->next; |
---|
1636 | p->next->back = r; |
---|
1637 | r->next->back = s; |
---|
1638 | s->back = r->next; |
---|
1639 | addElementLenMULT(fp, tr, r->next->next, partitionCounter); |
---|
1640 | } |
---|
1641 | } |
---|
1642 | |
---|
1643 | if(ch != ')') |
---|
1644 | { |
---|
1645 | printf("Missing /) in treeReadLenMULT\n"); |
---|
1646 | exit(-1); |
---|
1647 | } |
---|
1648 | else |
---|
1649 | ungetc(ch, fp); |
---|
1650 | } |
---|
1651 | else |
---|
1652 | { |
---|
1653 | tr->rooted = TRUE; |
---|
1654 | if (ch != EOF) (void) ungetc(ch, fp); |
---|
1655 | } |
---|
1656 | } |
---|
1657 | else |
---|
1658 | { |
---|
1659 | p->next->next->back = (nodeptr) NULL; |
---|
1660 | } |
---|
1661 | |
---|
1662 | if (! treeNeedCh(fp, ')', "in")) return FALSE; |
---|
1663 | (void) treeFlushLabel(fp); |
---|
1664 | if (! treeFlushLen(fp, tr)) return FALSE; |
---|
1665 | |
---|
1666 | if (! treeNeedCh(fp, ';', "at end of")) return FALSE; |
---|
1667 | |
---|
1668 | |
---|
1669 | if (tr->rooted) |
---|
1670 | { |
---|
1671 | p->next->next->back = (nodeptr) NULL; |
---|
1672 | tr->start = uprootTree(tr, p->next->next, FALSE, TRUE); |
---|
1673 | if (! tr->start) return FALSE; |
---|
1674 | } |
---|
1675 | else |
---|
1676 | { |
---|
1677 | tr->start = findAnyTip(p, tr->rdta->numsp); |
---|
1678 | } |
---|
1679 | |
---|
1680 | |
---|
1681 | |
---|
1682 | |
---|
1683 | if(tr->ntips < tr->mxtips) |
---|
1684 | makeParsimonyTreeIncomplete(tr, adef); |
---|
1685 | |
---|
1686 | |
---|
1687 | if(!adef->rapidBoot) |
---|
1688 | onlyInitrav(tr, tr->start); |
---|
1689 | return TRUE; |
---|
1690 | } |
---|
1691 | |
---|
1692 | |
---|
1693 | |
---|
1694 | |
---|
1695 | |
---|
1696 | |
---|
1697 | void getStartingTree(tree *tr, analdef *adef) |
---|
1698 | { |
---|
1699 | tr->likelihood = unlikely; |
---|
1700 | |
---|
1701 | if(adef->restart) |
---|
1702 | { |
---|
1703 | INFILE = myfopen(tree_file, "rb"); |
---|
1704 | |
---|
1705 | if(!adef->grouping) |
---|
1706 | { |
---|
1707 | switch(adef->mode) |
---|
1708 | { |
---|
1709 | case ANCESTRAL_STATES: |
---|
1710 | assert(!tr->saveMemory); |
---|
1711 | |
---|
1712 | tr->leftRootNode = (nodeptr)NULL; |
---|
1713 | tr->rightRootNode = (nodeptr)NULL; |
---|
1714 | |
---|
1715 | treeReadLen(INFILE, tr, FALSE, FALSE, FALSE, adef, TRUE, FALSE); |
---|
1716 | |
---|
1717 | assert(tr->leftRootNode && tr->rightRootNode); |
---|
1718 | break; |
---|
1719 | case CLASSIFY_MP: |
---|
1720 | treeReadLen(INFILE, tr, TRUE, FALSE, TRUE, adef, FALSE, FALSE); |
---|
1721 | break; |
---|
1722 | case OPTIMIZE_BR_LEN_SCALER: |
---|
1723 | treeReadLen(INFILE, tr, TRUE, FALSE, FALSE, adef, TRUE, FALSE); |
---|
1724 | break; |
---|
1725 | case CLASSIFY_ML: |
---|
1726 | if(adef->useBinaryModelFile) |
---|
1727 | { |
---|
1728 | if(tr->saveMemory) |
---|
1729 | treeReadLen(INFILE, tr, TRUE, FALSE, TRUE, adef, FALSE, FALSE); |
---|
1730 | else |
---|
1731 | treeReadLen(INFILE, tr, TRUE, FALSE, FALSE, adef, FALSE, FALSE); |
---|
1732 | } |
---|
1733 | else |
---|
1734 | { |
---|
1735 | if(tr->saveMemory) |
---|
1736 | treeReadLen(INFILE, tr, FALSE, FALSE, TRUE, adef, FALSE, FALSE); |
---|
1737 | else |
---|
1738 | treeReadLen(INFILE, tr, FALSE, FALSE, FALSE, adef, FALSE, FALSE); |
---|
1739 | } |
---|
1740 | break; |
---|
1741 | default: |
---|
1742 | if(tr->saveMemory) |
---|
1743 | treeReadLen(INFILE, tr, FALSE, FALSE, TRUE, adef, FALSE, FALSE); |
---|
1744 | else |
---|
1745 | treeReadLen(INFILE, tr, FALSE, FALSE, FALSE, adef, FALSE, FALSE); |
---|
1746 | break; |
---|
1747 | } |
---|
1748 | } |
---|
1749 | else |
---|
1750 | { |
---|
1751 | assert(adef->mode != ANCESTRAL_STATES); |
---|
1752 | |
---|
1753 | partCount = 0; |
---|
1754 | if (! treeReadLenMULT(INFILE, tr, adef)) |
---|
1755 | exit(-1); |
---|
1756 | } |
---|
1757 | |
---|
1758 | if(adef->mode == PARSIMONY_ADDITION) |
---|
1759 | return; |
---|
1760 | |
---|
1761 | if(adef->mode != CLASSIFY_MP) |
---|
1762 | { |
---|
1763 | if(adef->mode == OPTIMIZE_BR_LEN_SCALER) |
---|
1764 | { |
---|
1765 | assert(tr->numBranches == tr->NumberOfModels); |
---|
1766 | scaleBranches(tr, TRUE); |
---|
1767 | evaluateGenericInitrav(tr, tr->start); |
---|
1768 | } |
---|
1769 | else |
---|
1770 | { |
---|
1771 | evaluateGenericInitrav(tr, tr->start); |
---|
1772 | treeEvaluate(tr, 1); |
---|
1773 | } |
---|
1774 | } |
---|
1775 | |
---|
1776 | fclose(INFILE); |
---|
1777 | } |
---|
1778 | else |
---|
1779 | { |
---|
1780 | assert(adef->mode != PARSIMONY_ADDITION && |
---|
1781 | adef->mode != MORPH_CALIBRATOR && |
---|
1782 | adef->mode != ANCESTRAL_STATES && |
---|
1783 | adef->mode != OPTIMIZE_BR_LEN_SCALER); |
---|
1784 | |
---|
1785 | if(adef->randomStartingTree) |
---|
1786 | makeRandomTree(tr, adef); |
---|
1787 | else |
---|
1788 | makeParsimonyTree(tr, adef); |
---|
1789 | |
---|
1790 | if(adef->startingTreeOnly) |
---|
1791 | { |
---|
1792 | printStartingTree(tr, adef, TRUE); |
---|
1793 | exit(0); |
---|
1794 | } |
---|
1795 | else |
---|
1796 | printStartingTree(tr, adef, FALSE); |
---|
1797 | |
---|
1798 | |
---|
1799 | evaluateGenericInitrav(tr, tr->start); |
---|
1800 | |
---|
1801 | |
---|
1802 | |
---|
1803 | treeEvaluate(tr, 1); |
---|
1804 | |
---|
1805 | |
---|
1806 | |
---|
1807 | } |
---|
1808 | |
---|
1809 | tr->start = tr->nodep[1]; |
---|
1810 | } |
---|
1811 | |
---|
1812 | |
---|
1813 | |
---|
1814 | /****** functions for reading true multi-furcating trees *****/ |
---|
1815 | |
---|
1816 | /****************************************************************************/ |
---|
1817 | |
---|
1818 | static boolean addMultifurcation (FILE *fp, tree *tr, nodeptr _p, analdef *adef, int *nextnode) |
---|
1819 | { |
---|
1820 | nodeptr |
---|
1821 | p, |
---|
1822 | initial_p; |
---|
1823 | |
---|
1824 | int |
---|
1825 | n, |
---|
1826 | ch, |
---|
1827 | fres; |
---|
1828 | |
---|
1829 | if ((ch = treeGetCh(fp)) == '(') |
---|
1830 | { |
---|
1831 | int |
---|
1832 | i = 0; |
---|
1833 | |
---|
1834 | initial_p = p = tr->nodep[*nextnode]; |
---|
1835 | *nextnode = *nextnode + 1; |
---|
1836 | |
---|
1837 | do |
---|
1838 | { |
---|
1839 | p->next = tr->nodep[*nextnode]; |
---|
1840 | *nextnode = *nextnode + 1; |
---|
1841 | p = p->next; |
---|
1842 | |
---|
1843 | addMultifurcation(fp, tr, p, adef, nextnode); |
---|
1844 | i++; |
---|
1845 | } |
---|
1846 | while((ch = treeGetCh(fp)) == ','); |
---|
1847 | |
---|
1848 | ungetc(ch, fp); |
---|
1849 | |
---|
1850 | p->next = initial_p; |
---|
1851 | |
---|
1852 | if (! treeNeedCh(fp, ')', "in")) |
---|
1853 | assert(0); |
---|
1854 | |
---|
1855 | treeFlushLabel(fp); |
---|
1856 | } |
---|
1857 | else |
---|
1858 | { |
---|
1859 | ungetc(ch, fp); |
---|
1860 | if ((n = treeFindTipName(fp, tr, FALSE)) <= 0) |
---|
1861 | return FALSE; |
---|
1862 | p = tr->nodep[n]; |
---|
1863 | initial_p = p; |
---|
1864 | tr->start = p; |
---|
1865 | (tr->ntips)++; |
---|
1866 | } |
---|
1867 | |
---|
1868 | |
---|
1869 | fres = treeFlushLen(fp, tr); |
---|
1870 | if(!fres) |
---|
1871 | return FALSE; |
---|
1872 | |
---|
1873 | hookupDefault(initial_p, _p, tr->numBranches); |
---|
1874 | |
---|
1875 | return TRUE; |
---|
1876 | } |
---|
1877 | |
---|
1878 | static void printMultiFurc(nodeptr p, tree *tr) |
---|
1879 | { |
---|
1880 | if(isTip(p->number, tr->mxtips)) |
---|
1881 | printf("%s", tr->nameList[p->number]); |
---|
1882 | else |
---|
1883 | { |
---|
1884 | nodeptr |
---|
1885 | q = p->next; |
---|
1886 | |
---|
1887 | printf("("); |
---|
1888 | |
---|
1889 | while(q != p) |
---|
1890 | { |
---|
1891 | printMultiFurc(q->back, |
---|
1892 | tr); |
---|
1893 | q = q->next; |
---|
1894 | if(q != p) |
---|
1895 | printf(","); |
---|
1896 | } |
---|
1897 | |
---|
1898 | printf(")"); |
---|
1899 | } |
---|
1900 | } |
---|
1901 | |
---|
1902 | void allocateMultifurcations(tree *tr, tree *smallTree) |
---|
1903 | { |
---|
1904 | int |
---|
1905 | i, |
---|
1906 | tips, |
---|
1907 | inter; |
---|
1908 | |
---|
1909 | smallTree->numBranches = tr->numBranches; |
---|
1910 | |
---|
1911 | smallTree->mxtips = tr->mxtips; |
---|
1912 | |
---|
1913 | smallTree->nameHash = tr->nameHash; |
---|
1914 | |
---|
1915 | tips = tr->mxtips; |
---|
1916 | inter = tr->mxtips - 1; |
---|
1917 | |
---|
1918 | smallTree->nodep = (nodeptr *)rax_malloc((tips + 3 * inter) * sizeof(nodeptr)); |
---|
1919 | |
---|
1920 | smallTree->nodep[0] = (node *) NULL; |
---|
1921 | |
---|
1922 | for (i = 1; i <= tips; i++) |
---|
1923 | { |
---|
1924 | smallTree->nodep[i] = (nodeptr)rax_malloc(sizeof(node)); |
---|
1925 | memcpy(smallTree->nodep[i], tr->nodep[i], sizeof(node)); |
---|
1926 | smallTree->nodep[i]->back = (node *) NULL; |
---|
1927 | smallTree->nodep[i]->next = (node *) NULL; |
---|
1928 | } |
---|
1929 | |
---|
1930 | for(i = tips + 1; i < tips + 3 * inter; i++) |
---|
1931 | { |
---|
1932 | smallTree->nodep[i] = (nodeptr)rax_malloc(sizeof(node)); |
---|
1933 | smallTree->nodep[i]->number = i; |
---|
1934 | smallTree->nodep[i]->back = (node *) NULL; |
---|
1935 | smallTree->nodep[i]->next = (node *) NULL; |
---|
1936 | } |
---|
1937 | |
---|
1938 | } |
---|
1939 | |
---|
1940 | void freeMultifurcations(tree *tr) |
---|
1941 | { |
---|
1942 | int |
---|
1943 | i, |
---|
1944 | tips = tr->mxtips, |
---|
1945 | inter = tr->mxtips - 1; |
---|
1946 | |
---|
1947 | for (i = 1; i < tips + 3 * inter; i++) |
---|
1948 | rax_free(tr->nodep[i]); |
---|
1949 | |
---|
1950 | rax_free(tr->nodep); |
---|
1951 | } |
---|
1952 | |
---|
1953 | static void relabelInnerNodes(nodeptr p, tree *tr, int n, int *nodeCounter) |
---|
1954 | { |
---|
1955 | if(isTip(p->number, tr->mxtips)) |
---|
1956 | { |
---|
1957 | assert(0); |
---|
1958 | } |
---|
1959 | else |
---|
1960 | { |
---|
1961 | nodeptr |
---|
1962 | q = p->next; |
---|
1963 | |
---|
1964 | int |
---|
1965 | _n = n; |
---|
1966 | |
---|
1967 | tr->nodep[p->number]->number = n; |
---|
1968 | p->x = 1; |
---|
1969 | |
---|
1970 | while(q != p) |
---|
1971 | { |
---|
1972 | tr->nodep[q->number]->number = n; |
---|
1973 | q->x = 0; |
---|
1974 | |
---|
1975 | if(!isTip(q->back->number, tr->mxtips)) |
---|
1976 | { |
---|
1977 | _n++; |
---|
1978 | *nodeCounter = *nodeCounter + 1; |
---|
1979 | relabelInnerNodes(q->back, tr, _n, nodeCounter); |
---|
1980 | } |
---|
1981 | q = q->next; |
---|
1982 | } |
---|
1983 | } |
---|
1984 | } |
---|
1985 | |
---|
1986 | |
---|
1987 | int readMultifurcatingTree(FILE *fp, tree *tr, analdef *adef) |
---|
1988 | { |
---|
1989 | nodeptr |
---|
1990 | p, |
---|
1991 | initial_p; |
---|
1992 | |
---|
1993 | int |
---|
1994 | innerBranches = 0, |
---|
1995 | nextnode, |
---|
1996 | i, |
---|
1997 | ch, |
---|
1998 | tips = tr->mxtips, |
---|
1999 | inter = tr->mxtips - 1; |
---|
2000 | |
---|
2001 | //clean up before parsing ! |
---|
2002 | |
---|
2003 | for (i = 1; i < tips + 3 * inter; i++) |
---|
2004 | { |
---|
2005 | tr->nodep[i]->back = (node *) NULL; |
---|
2006 | tr->nodep[i]->next = (node *) NULL; |
---|
2007 | tr->nodep[i]->x = 0; |
---|
2008 | } |
---|
2009 | |
---|
2010 | for(i = tips + 1; i < tips + 3 * inter; i++) |
---|
2011 | tr->nodep[i]->number = i; |
---|
2012 | |
---|
2013 | tr->ntips = 0; |
---|
2014 | nextnode = tr->mxtips + 1; |
---|
2015 | |
---|
2016 | while((ch = treeGetCh(fp)) != '('); |
---|
2017 | |
---|
2018 | i = 0; |
---|
2019 | |
---|
2020 | do |
---|
2021 | { |
---|
2022 | if(i == 0) |
---|
2023 | { |
---|
2024 | initial_p = p = tr->nodep[nextnode]; |
---|
2025 | nextnode++; |
---|
2026 | } |
---|
2027 | else |
---|
2028 | { |
---|
2029 | p->next = tr->nodep[nextnode]; |
---|
2030 | p = p->next; |
---|
2031 | nextnode++; |
---|
2032 | } |
---|
2033 | |
---|
2034 | addMultifurcation(fp, tr, p, adef, &nextnode); |
---|
2035 | |
---|
2036 | i++; |
---|
2037 | } |
---|
2038 | while((ch = treeGetCh(fp)) == ','); |
---|
2039 | |
---|
2040 | if(i < 3) |
---|
2041 | { |
---|
2042 | printBothOpen("You need to provide unrooted input trees!\n"); |
---|
2043 | assert(0); |
---|
2044 | } |
---|
2045 | |
---|
2046 | ungetc(ch, fp); |
---|
2047 | |
---|
2048 | p->next = initial_p; |
---|
2049 | |
---|
2050 | if (! treeNeedCh(fp, ')', "in")) |
---|
2051 | assert(0); |
---|
2052 | |
---|
2053 | (void)treeFlushLabel(fp); |
---|
2054 | |
---|
2055 | if (! treeFlushLen(fp, tr)) |
---|
2056 | assert(0); |
---|
2057 | |
---|
2058 | if (! treeNeedCh(fp, ';', "at end of")) |
---|
2059 | assert(0); |
---|
2060 | |
---|
2061 | //printf("%d tips found, %d inner nodes used start %d maxtips %d\n", tr->ntips, tr->nextnode - tr->mxtips, tr->start->number, tr->mxtips); |
---|
2062 | |
---|
2063 | assert(isTip(tr->start->number, tr->mxtips)); |
---|
2064 | |
---|
2065 | relabelInnerNodes(tr->start->back, tr, tr->mxtips + 1, &innerBranches); |
---|
2066 | |
---|
2067 | //printf("Inner branches %d\n", innerBranches); |
---|
2068 | |
---|
2069 | if(0) |
---|
2070 | { |
---|
2071 | printf("("); |
---|
2072 | printMultiFurc(tr->start, tr); |
---|
2073 | printf(","); |
---|
2074 | printMultiFurc(tr->start->back, tr); |
---|
2075 | printf(");\n"); |
---|
2076 | } |
---|
2077 | |
---|
2078 | return innerBranches; |
---|
2079 | } |
---|
2080 | |
---|