source: trunk/arb_CHANGES.txt

Last change on this file was 19532, checked in by westram, 5 weeks ago
  • reintegrates 'help' into 'trunk'
    • tweak arb documentation:
      • automatically link
        • ticket references to arb bug tracker (only affects html version).
        • found URLs.
      • page titles
        • warn about long titles.
        • introduce SUBTITLEs (automatically triggered by multi-line titles in source files).
        • increase allowed length (limited by subwindow width).
      • cleanup header sections in all helpfiles.
      • fix and/or update several help files.
      • document syntax of help sources.
      • build issues:
        • when xml validation fails, next build no longer uses invalid xml ⇒ keeps failing.
        • remove output files on error (including files below ARBHOME/lib).
        • pipe output through logs to ensure proper wrapping in Entering/Leaving lines.
    • moves Tree admin + NDS menu entries to top of menu
  • adds: log:branches/help@18783:19531
  • Property svn:eol-style set to native
  • Property svn:keywords set to Author Date Id Revision
File size: 26.7 KB
Line 
1ARB change log
2
3Ticket references
4
5    Referenced ticket numbers are linked when you view this information
6    at http://help.arb-home.de/changes.html
7
8Major changes for next release:
9
10 - tweaked 'Helix settings' in EDIT4
11   - defaults changed for GG ('#'->'='), TT + UU ('+'->'#'), ambiguity codes (''->'%')
12   - added several predefined configs (traditional, two handling ambiguity codes)
13 - detect poorly aligned helical regions in editor (#854)
14 - include SINA (1.7.2 patched)
15   - interface auto-adapts to sina version (still compatible with 1.3; currently needs patched version for 1.7.2)
16   - added script arb_sina_install_from_fat_tarball.sh (allows to install sina from fat-tarballs provided via arb homepage)
17 - split alignments (#846)
18 - tweaked progress
19   - better estimation for NJ, ConsensusTree, matrix calculation + PVP
20   - support for longer periods; prefer overestimation
21   - log to console (estimates finish)
22 - FastTree
23   - added support for protein sequences.
24   - customizable from GUI (rate categories, NJ, bootstraps).
25   - upgraded to version 2.1.11
26   - arb now provides single+multi processor versions of FastTree
27 - NDS (Node display setup)
28   - specifying a zero WIDTH now means "unlimited" (backward compatible).
29   - avoid unwanted truncation (NDS-export, saved distance matrix).
30   - tree/export (using NDS)
31     - no longer truncates labels.
32     - group-labels are generated by NDS now.
33     - raise an error if non-ASCII characters are used in label (optionally).
34
35Fixes for arb-7.0.1 (31 Jan 2022):
36
37 - fix perl compatibility for macOS 12
38
39Major changes for arb-7.0 (1 Sep 2021):
40
41 - ARB PARSIMONY
42   * topology optimization
43     - now (by default) strictly restricted to marked/visible parts of the tree (#640)
44     - restriction now customizable (marked/all; visible/all)
45     - tree costs for protein-data were not independent from root-position (as expected by model; #633).
46       Caused infinite running optimization under some circumstances.
47     - optimize-modes now strictly restrict to clicked subtrees. single/repeated optimization possible.
48     - KL-optimizer
49       * static path reduction slightly changed meaning. changed default settings.
50       * removed randomness (was just covering some bugs)
51       * improved general optimization speed
52   * branchlength calculation
53     - "forgot" to recalculate lengths under some conditions. fixed.
54     - is now independent of tree-root position (#641)
55   * adding species
56     - 'add partial species' failed if two partial species had NO overlap (#609). fixed.
57     - in 'add species + NNI' local optimization quality depended on insert position. fixed.
58     - insertion of multiple species is now done independently (=unordered; #643)
59     - performance improved (esp. for many added species/big trees; #643)
60   * generally improved combine performance (using SSE)
61   * generally reduced the number of performed combines (skipping many useless)
62   * added function to randomize (parts of) the tree
63   * warns about insufficient sequence data (e.g. as result of too restrictive filtering; #631)
64   * fixed 'RESTORE' (crashed after deleting species from tree; #528)
65   * corrected handling of dots ('.') while combining ancestor sequences
66   * fixed a bunch of internal bugs (#620, #627, #645, ...)
67   * added species-info mode
68 - added missing translation tables (genetic codes 24-31)
69 - added amino acid code Xle(=J), which means Ile(=I) or Leu(=L)
70 - DNA realigner
71   * several unjustified failures will no longer happen (fixes #419 and most likely #145)
72     - correctly re-syncs after 'X' (if possible at all)
73     - no longer fails for 'B', 'J' and 'Z'
74     - accepts 3 or more consecutive IUPAC codes in DNA
75   * added option to cut-off DNA sequence (was done at end of sequence by old version. fixed)
76   * fixed several minor bugs (#563,..)
77 - ARB probeSpec: visualisation of probe set specificity (thanks to Paavo Jumppanen, CSIRO)
78 - species selections (editor configurations):
79   * visualisation of multiple selections in standard tree view (#658; example in database demo.arb)
80   * order can be changed; each configuration has a comment
81 - import/export (species,sequence):
82   * manage/edit/test import-/export-filter-definitions from inside ARB (#691)
83   * import can store configuration of imported species (#607)
84   * field transfer sets (#562) may be used to customize import/export behavior (also usable from arb merge-tool)
85   * corrected EMBL export filter (numbers at seq.data; #638)
86   * detected duplicates no longer abort complete import (#779)
87   * new CLI sequence exporter 'arb_export_seq_filtered' (#743)
88 - Tree shading (#443)
89   * according to values stored in database
90   * according to given topology (useful when comparing topologies)
91   * added customisable color ranges (#682)
92 - support for extra database compression (using gzip, bzip2, xz; #665); databases cannot be opened by versions before arb-7.0
93 - ARB_EDIT4:
94   * display selected database fields as flags (allowing to toggle their value; #261).
95     Example use: easily mark sequence as "curated" after manually checking its alignment.
96   * allow to load missing SAIs
97   * "view differences" to a reference sequence:
98      - customizable:
99        * char used for "equality" (i.e. what is displayed where a sequence is equal to selected sequence)
100        * case-sensitivity
101        * ignore different gap-types
102      - equal data also gets hidden in consensus
103      - refresh differences of all displayed sequences, when data of selected sequences changes
104      - change reference sequence using CTRL-R or automatically let it follow the cursor
105      - added hotkey to toggle mode: CTRL-D
106      - fixed minor bugs
107   * consensus calculation in ARB_EDIT4 and calculation of CONSENSUS SAI
108     - now both calculations are strictly consistent (#663):
109       * gaps are now ignored while deciding whether to simplify using IUPAC ambiguity codes
110       * IUPAC ambiguity codes encountered in sequence data are now counted proportionally (=> fewer 'N's occur in consensus)
111     - added sliders to consensus definition windows
112     - user defined consensus settings exchangable between both consensus setups
113     - fixed and updated documentation
114   * added species-info mode + database save (#52,#362)
115   * predefined SAI color translation for PVP
116 - changes to SAI generation
117   * MAX_FREQUENCY:
118     - considers IUPAC ambiguity codes proportionally
119     - amino acids: if MAX_FREQUENCY is below 10% SAI now shows '1' (prev. it did show '0', i.e. 100%)
120   * POS_VAR_BY_PARSIMONY (PVP):
121     - now (again) works with amino acid data (#782)
122     - added CLI tool 'arb_calc_pvp' (#701)
123   * implemented a SAI calculator (allows to modify or combine multiple SAIs)
124 - expand zombies in tree (unfold groups; #22)
125 - compare taxonomy (and mark differences; #651)
126 - search&query for taxonomic groups (#652)
127   - many search criteria (name, size, marked, nesting-level, ingroup-distance (#653), ...)
128   - search multiple trees, detect duplicate and missing groups
129   - operations on found groups (delete, rename, fold, mark)
130 - added concept of "inverse groups" (aka "keeled groups"; #735)
131 - group transfer between trees (#780):
132   - penalties can be customized in detail
133   - quality reports (to log and optionally to target name)
134 - synchronize positions of roots of multiple trees (#449)
135 - external (command line) aligners (#504):
136   * fixed incorrect handling of 'T' vs 'U': now all aligned sequences will contain the correct base depending on alignment type
137   * preserve gap-type ('-' vs '.') and upper-/lower-case of original alignment
138   * no longer ask what to do with aligned sequence, just overwrite it
139     - only warn about real sequence changes (so please do NOT ignore from now on!)
140 - config-managers:
141   * possibility to restore factory defaults
142   * added comment field for configurations
143   * added them throughout arb (#647)
144 - added slide controls throughout arb (#656)
145 - tree (display) options:
146   * fine grained scaling
147   * group display (shading, customizable counters (#118,#209), triangle clades, name display position)
148   * bootstrap values (filter by upper/lower limits, display position/styles, on/off toggle; #614)
149   * diagonal branch style (#578)
150   * parent branch position
151   * all options are now also supported by ARB_PARSIMONY
152   * improved auto-jump; now also works for groups
153   * added optional auto-unfolding (to selected group/species)
154   * select group on fold/unfold/create/move/..
155   * draw selected group in cursor-color (#709)
156   * added keys for tree-traversal (moving to selected species or group; #687)
157 - synchronized tree scrolling (#683)
158 - colorsets were invalidated by generating new IDs (#660). fixed.
159 - added alternate RAxML (DNA only; version 8.2.8)
160   - multicore support (automatically activates recommended number of threads)
161   - evaluation, optimization and extension of existing trees with RAxML (#681)
162 - fix performance of
163   * "format sequences" (broken in arb-6.0.x series; #702)
164   * nameserver for huge databases (#646)
165   * closing arb (if database uses fastload file; #649)
166 - ACI
167   - added boolean operators, numeric comparisons, floating point arithmetic and several other new commands
168   - allow access to other species via ID or accession number (findspec, ...)
169   - improved ACI debugging: more verbose tracing (console log accessible from inside ARB)
170 - NDS optionally uses only visible definitions
171 - Search&Query:
172   * sort results numerically (#203)
173   * recursive search through all fields (#773)
174 - Species information window: improved detachment, field selection (#695)
175 - improved macro compatibility:
176   * check compatibility with installed perl version during arb startup (#754)
177   * esp. tweaked compatibility of 'Search&Query' and 'Species information window'
178   * fixed a lot of internal names (missing or duplicated) which are used for macros (#429)
179 - improved OSX compatibility (thx to Jan Gerken)
180 - updated integrated documentation (#409)
181
182
183Fixes for arb-6.0.6 (22 Aug 2016):
184
185 - fixes for gcc 6.1.0
186 - tested gcc 4.9.4 + 5.4.0
187
188Fixes for arb-6.0.5 (4 May 2016):
189
190 - fixes for ubuntu 16.04 build
191
192Fixes for arb-6.0.4 (2 May 2016):
193
194 - fixes for OSX build (SIP, accepted compilers)
195
196Fixes for arb-6.0.3 (19 Nov 2015):
197
198 - fixes permission problems when multiple users share databases or ptservers (thx to Alan McCulloch)
199
200Fixes for arb-6.0.2 (8 Aug 2014):
201
202 - compile issues on Snow Leopard (OSX 10.6)
203 - merge Debian security fix for CVE-2008-5378
204 - small changes to build system for Debian
205 - add desktop integration files
206
207Fixes for arb-6.0.1 (22 Jul 2014):
208
209 - arb_parsimony
210   - skip unwanted automatic branchlength recalculations (e.g. by unfolding a group)
211   - corrected branchlength calculation for "Add marked partial species"
212   - dots were treated as gaps for protein sequences (now treated as 'X'; analog to DNA treating gaps as 'N'; #144). thx to Yan Shi for detecting that problem!
213 - print
214   - preview failed (showed empty postscript file)
215   - print to file now always saves in user home
216 - raxml (import tree with bootstrap values)
217
218Major changes for arb-6.0 (4 Jun 2014):
219
220 - merge databases allows to
221   - merge from an existing database into the database loaded in ARB_NT
222   - merge to existing databases from the database loaded in ARB_NT
223 - ARB can now
224   - be restarted with another database and
225   - a second instance of ARB can be opened
226 - ARB_DIST
227   - Detect clusters of species with similar sequences (OTUs)
228   - allow automatic recalculation of matrix and/or tree whenever some parameter or
229     data changes (only makes sense for smaller species sets)
230   - extract distance matrix from tree
231 - Rewrote chimera check. Allows filtering
232 - added RNACMA (computes clusters of correlated positions)
233 - PT-Server
234   - changed behavior
235     - no longer report less hits for a part of a probe than for the probe itself (occurred at 3'-end of alignment)
236     - reports previously missing hits in joined genes
237     - reports more hits at 3'-end of alignment (when using mismatches the PT-server now reports possible
238       matches that go beyond the end of the sequence)
239     - dots in the middle of the alignment act like the sequence ends there
240     - minimum probe length reduced to 2 (was 6)
241     - allow up to 50% of probe to mismatch
242   - performance
243     - optimized memory-estimation (will build in fewer passes)
244     - uses any number of passes (not only 1, 5, 25, ...)
245     - allows to define used memory by setting environment variable ARB_MEMORY
246     - reduced memory needed to build/run ptserver (approx. 50%)
247     - reduced size of indexfile (.pt) to ~50%
248     - fast startup of existing ptservers
249   - probe design
250     - faster in many cases
251     - allow to design probes of length 8 (previously 10)
252     - allow to design probes with different lengths (specifying min/max length)
253     - fixed number of outgroup hits reported when decreasing temperature
254       (now each outgroup member only occurs once)
255     - show possible reasons why no probes could be designed
256   - probe match (allow any number of mismatches)
257   - next relative search
258     - can be restricted to column ranges (needs a PT-Server calculated from aligned sequences)
259     - corrected and improved scaling of relative scores
260     - more accurate scores (due to fixes in PT-Server; see below)
261     - faster in many cases
262   - show errors from ptserver build in ARB
263 - fast-aligner
264   - searches next-relatives based on selected column-block
265   - align multiple column-blocks based on SAI
266 - Rewrote alignment adaption during merge
267 - Insert/delete columns using a SAI to define affected columns
268 - ARB_EDIT4
269   - improved support for using multiple edit-windows
270   - smoother refreshes
271   - tweaked ORF display
272 - tree importer/exporter
273   - ARBs extended newick format (with bootstrap values) handled more restrictive now
274   - fixed several bugs; improved errors/warnings
275 - consensus trees
276   - calculate from multiple existing trees (also allows to merge not completely overlapping trees)
277   - fixed NJ-bootstrapping (no longer drops species)
278 - tree display
279   - Show brackets on open groups (dendrogram tree only)
280   - rewrote IRS (folded) display
281   - fixed tree key-bindings (mark, fold, ...)
282   - improved several tree-commands (move, rotate, spread, length, width)
283 - added a branch analysis tool
284   - groups several functions previously available via menuitems (e.g. mark long branches, etc.)
285   - added leaf-distance analysis
286 - other tree functionality
287   - treelist sortable now
288   - new beautify-tree modes (radial tree / according to other tree)
289   - function to remove marked/zombies from ALL trees
290   - create multifurcations (by branchlength/bootstrap limit)
291   - toggle 100% bootstrap values
292 - tweaked printing (interface, overlapping)
293 - if YOU edit a helpfile it will be automatically packed into an archive ready to be sent to ARB developers
294 - probe design:
295   - added LOAD to result window
296 - automation
297   - macro recording works in ARB client applications (ARB_EDIT4, ARB_PARS, ARB_MERGE, ..)
298   - arb_ntree can execute macro from command line
299   - added "Never ask again" to modal question boxes (for better compatibility with macros)
300   - a macro can be called for all marked species (once for each)
301   - macros can be nested (i.e. can call other macros)
302 - support for user-specific customization:
303   - of GDE menus (in ~/.arb_prop/gde)
304   - of import/export filters (in ~/.arb_prop/filter)
305 - ACI (some new commands, bugfixes)
306 - updated/added external tools:
307   - added FastTree (version 2.1.7)
308   - added MAFFT (version 7.055)
309   - added MrBayes (version 3.2.1)
310   - added MUSCLE (version 3.8.31)
311   - added PHYML (2013/07/08; also kept old version 2.4.5)
312   - added PROBCONS (version 1.12)
313   - updated RAxML (version 7.7.2)
314 - load/save for window specific settings (e.g. allows to share parts of configuration with other users)
315 - Support for mouse-wheel
316 - many unlisted bugfixes
317 - many internal refactorings
318
319
320Fixes for arb_5.5 (15 Nov 2012):
321
322 * arb_5.4 was broken (several external tools missing)
323
324
325Fixes for arb_5.4 (14 Nov 2012):
326
327 * make it obvious when probe matches are truncated. Truncate all hits beyond 1 million (was 100000)
328 * fixed realigner (better interaction with fields 'transl_table' and 'codon_start'; improved error handling)
329 * fixed several compilation issues (OSX; recent distro releases)
330
331
332Fixes for arb_5.3 (10 Nov 2011):
333
334 - bugfixes
335   - fixed wrong absolute/ecoli position reported for some designed probes
336   - decompression error handling (pt-server build issues)
337   - fixed 'codon_start' generated with wrong type
338   - fixed a buffer overflow in ACI
339   - report failures to write to /tmp
340 - changes
341   - markSpecies.pl:
342     mark by accession number
343     partial/ambiguous matches
344 - internal fixes
345   - compilation fixes for OSX
346   - some patches for debian version (removed refs to xview, textedit, removed molphy(protml))
347   - removed obsolete dependency from libXp
348
349
350Fixes for arb_5.2 (5 Sep 2010):
351
352 - bugfixes
353   - quicksave did silently do nothing (especially not save anything) if an error occurred
354   - ARB_EDIT4: crashed when using config with MANY unknown species
355   - ARB_SECEDIT: crashed when trying to paint strand w/o any base
356   - ARB_NTREE/ARB_PARS: crashed when clicking on inner tree node w/o groupinfo
357 - changes
358   - ARB uses xdg-open to display web-pages
359 - internal fixes
360   - karmic koala (gcc 4.4.1)
361   - installation script
362   - arb build process uses xsltproc instead of sablotron
363
364
365Fixes for arb_5.1 (1 Oct 2009):
366
367 - fixed a bug in 'Create species from consensus' (created sequence was corrupted)
368 - fixed 2 bugs in optimize DB (alignment w/o data, missing transaction)
369 - updated installation instructions, fixed install script, added OSX instruction (thx to Matt Cottrell)
370 - fixed broken demo.arb
371
372
373Major changes for arb_5.00 (4 Sep 2009):
374
375 - ARB 64bit version
376 - new genome importer
377 - search for next relatives improved (normal search and fast-aligner)
378   - new parameters to precise search
379   - improved speed
380   - partial sequence reach normal scores
381 - search&query
382   - supports regular expressions and ACI
383   - track hit information
384   - result sorting
385 - Nameservers with add.field have to be started with default value
386   You need to correct parameter -f in lib/arb_tcp.dat (according to lib/arb_tcp_org.dat)
387 - multiple PT-servers may be used in parallel
388 - fixed multiprobe
389 - type-conversion for DB fields
390 - SILVA compatible import filters
391 - Newick tree export:
392   - optionally save in human-readable format (big)
393   - closer to newick standard format (quoting style, comment, special chars in data)
394 - Upgraded RAxML to 7.0.3 (many features now usable from ARB interface)
395 - Fixed sequence quality calculation
396 - Secondary structures for proteins (DSSP)
397 - Distance matrix (arb_dist): mark by distance to selected
398 - ARB core
399   - many bugfixes and improvements to reliability
400   - faster sorting (general speedup)
401   - improved sequence compression (avoid worse trees, better ratio)
402   - improved handling of temporary files (permission/removal)
403   - prints backtraces in userland
404   - regular expression are POSIX standard now
405 - macro record/playback
406   - fixed several bugs
407   - you need to re-record your old macros!
408 - GUI:
409   - disabled auto-focus, you need to click now
410   - auto-raise windows on access
411 - Minor things:
412   - Ubuntu: packet installation for ARB
413   - Fixed novice/expert mode
414   - Mark deep/degenerated branches
415   - Increased NDS entries
416 - up-to-date Mac port (thx to Matt Cottrell)
417
418Major changes in ARB 07.12.07org (7 Dec 2007):
419
420 - rewrote secondary structure editor
421 - Sequence quality check
422 - Nameserver may use one field additional to 'acc' (useful to keep multiple species with same acc)
423 - tweaked base frequency filter generation
424 - Normal export (not using readseq) improved:
425   - supports filters and gap removal
426   - optimized for big amount of data
427   - reworked export filters
428 - Display translation with different ORFs in EDIT4
429 - ARB exports in FIG 3.2 format (optionally in colors). Thanks to Elmar Pruesse.
430 - added PHYML 2.4.5 (thanks to Stephane Guidon for the permission to distribute that great tool)
431 - more compact display in EDIT4
432 - capable to use iso10646 fonts
433 - supports various gcc versions (2.95.3 - 4.1.1)
434 - fixed a bug in DB optimization (occurred when fields had bigger protection than current)
435 - Bootstrap circles may be displayed as ellipses; upper size limit configurable; uses
436   different color for size-limited circles; fixed xfig-export-bug
437 - Allows Branchlength <-> Bootstrap value transfer (lossy!)
438 - fixed several scaling bugs in "folded tree"-mode
439 - improved import-filter error-messages
440 - NDS-display of groups (e.g. in tree) is now handled by ACI-command 'taxonomy'. This gives
441   several new possibilities:
442   - export taxonomy via 'Export NDS list'
443   - display taxonomy in Editor etc.
444   - display of cascaded taxonomies
445   - display taxonomy of tree_1 in tree_2
446   - allows to write taxonomy into database field of species
447   - compare taxonomies of two trees
448   - ...
449 - ACI:
450   - many new ACI commands
451   - unified handling of binary ACI-operators
452   - tracing of ACI actions for debugging purpose
453 - ARB Neighbour joining:
454   - bootstrap limit configurable
455   - bugfix: when aborting bootstrap calculation, sometimes no tree was generated
456 - EDIT4:
457   - added unalign right (block-op)
458   - added 'Save loaded properties'
459 - GENE MAP:
460   - multiple views possible at the same time
461   - origin now at "12 o'clock"
462   - implemented 'jump to gene'
463 - tweaked file selection
464 - Enhanced Search Depth for Probe Match --> max 20 MM
465 - CLUSTALW:
466   - separated menus for fast and slow alignment
467   - most parameters accessible from inside ARB now
468 - upgraded to PHYLIP 3.6 (adds PROML)
469 - external programs may be called parallel (e.g. several treeing programs)
470 - fixed bugs in protml and integration of protml
471 - rewrote ASCII database import
472 - arb_repair for databases of any size (script for database repair)
473 - fixed bug in data compression
474 - increased internal cache size (alignments up to 400.000bp possible w/o performance collapse)
475 - ARBparsimony: increase hardcoded species limit (50.000 -> 250.000)
476 - GDE menus cleanup
477 - translation/re-alignment tweaked
478 - unalign right (EDIT4)
479 - visualization of SAIs in Probe Match Results
480 - changed formatting of probe match results; increase # of allowed matches to 100.000;
481   warn if results are truncated
482 - PT server for genes
483 - Probe design performance optimized
484 - fixed NEXUS export format
485 - exports group names into Newick format
486 - import XML tree files
487 - help for external tools now properly shown inside ARB
488
489Major changes in Beta 2003_08_22 (22 Aug 2003):
490
491 - automatic formatting of alignments
492 - SECEDIT may use EDIT4 colors
493 - fixed bootstrapping (DNAPARS, PROTPARS, PROTML(experimental!))
494 - updated clustalw to version 1.83
495 - Restore window sizes for ALL windows (too small sizes are ignored)
496 - new algorithm to add partial sequences to an existing tree
497 - PROT-parsimony was completely redesigned and works now most similar to DNA/RNA-parsimony
498 - Top area of ARB_NTREE may be reduced to maximize display area
499 - All arb menus may be detached (click dashed line at top of menu)
500 - visualization of SAIs (as background color behind Sequences)
501 - ARB_EDIT4 may save/use alignment-specific and alignment-type-specific properties
502 - PT-server occupies more memory => does less passes; more diagnostic output
503 - small changes to status window (unhide behavior/time estimation)
504 - menus and menu-hotkeys reorganized
505 - colored buttons in color config windows
506 - alignment concatenation (e.g. several different genes)
507 - merging data of similar species (according selected database field)
508 - keyboard commands for ARB_NTREE (mark/unmark/invert, collapse/expand)
509 - expanded sellists
510 - save/load fixed for multi probes
511 - Binary SAIs are editable in ARB_EDIT4
512 - Information windows are detachable (allows to have multiple windows showing different items)
513 - Scanning for hidden/unknown database fields improved and separated;
514   possibility to remove unused fields.
515 - new tabbed format in 'Export NDS' and 'Export matrix' (useful for star-calc/excel/etc.)
516 - updated fastDNAml to 1.2.2
517 - added AxML (accelerated fastDNAml 1.2.2)
518 - Field transfer definitions for exporting gene-species
519 - File Selection: - recursive search available
520 - The ARB_NTREE macro recording/execution has been fixed
521 - Colorize species (see demo.arb)
522 - Fixed missing-character-bug in Xfig, Print and Edit4-Info-Display
523 - 'IslandHopper' -- a new integrated aligner (beta)
524 - Many improvements and bugfixes to secondary structure editor:
525   - highlighting of search (i.e for probes) like in EDIT4
526   - interactive constraint editing (stretch/compress)
527   - probe info
528   - editing secondary structure in XFIG now possible
529   - visualization of SAIs
530 - import reads Unix, DOS, and MAC linefeeds
531 - NTREE/SAI/Etc/GnuPlot: calls gnuplot directly; more plotting features; basic help
532 - tree and sequence export to XML ( DTDs are provided in ./lib/dtd )
533   (reloading of these XML files is planned for the future)
534 - fixed problems with phylip-tree import/export (bootstrap values,comments,...)
535 - search in all database fields possible ('[all fields]')
536 - up to 10 quicksaves are kept
537 - new ACI functions: upper, lower, caps, eval
538 - variables for import filter programming
539 - extract gene-species: creates acc; extraction to existing alignments
540 - sequence of selected gene is mirrored in ARB_EDIT4/local_signature
541   (=> selected gene can be highlighted in primary editor)
542 - PCR primer-design for single genes
543 - when selecting a gene, the corresponding gene-species is selected (if found)
544 - save configuration for several windows (e.g. Search&Query, WWW, NDS, ...)
545 - file selection box in import window
546 - mark item with double click works in all search&query windows
547 - User masks: create new; 'edit enable' and 'marked' toggles (like in info window)
548 - Fixed command line help for all Arb-modules
549 - Fixed problem parsing fonts (should fix display problems with default fonts)
550 - Mark mode now works in list-view as well (ARB_NTREE)
551 - Fixed appearance of 'tiny little boxes' (everywhere)
552 - Redesign of ARB help:
553     - a HTML version is in $ARBHOME/lib/help_html
554     - a text version is in $ARBHOME/lib/help (like before, but now generated)
555
556Major changes in Beta 2001_11_07 (7 Nov 2001):
557
558 - design probes to maximum length of 60 nucleotides
559 - fastAligner1.03 bug fixed (chooses best match now in 'auto search' mode)
560 - import default changed to foreign data format, ali name '16s'
561 - printing of multi-page-trees works again
562 - implemented user defineable masks to access database fields
563 - fixed bugs in pt-server (lockup, unknown species just after building pt-server)
564 - improved performance during pt-server-build
565 - several programs coming along with ARB where updated (PHYLIP,...)
566 - reads EMBL genom files
567 - support for experiments (genom databases only)
568
569Major changes in Beta 2001_07_24 (24 Jul 2001):
570
571 - basic support for genoms (Gene Map, reads Genebank files)
572 - ported to libc6
573
574Changes in ancient versions (last century):
575
576 - see http://help.arb-home.de/version.html
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