source: trunk/arb_CHANGES.txt

Last change on this file was 19575, checked in by westram, 18 hours ago
  • reintegrates 'help' into 'trunk'
    • preformatted text gets checked for width now (to enforce it fits into the arb help window).
    • fixed help following these checks, using the following steps:
      • ignore problems in foreign documentation.
      • increase default help window width.
      • introduce control comments to
        • accept oversized preformatted sections.
        • enforce preformatted style for whole sections.
        • simply define single-line preformatted sections
          Used intensive for definition of internal script languages.
    • fixed several non-related problems found in documentation.
    • minor layout changes for HTML version of arb help (more compacted; highlight anchored/all sections).
    • refactor system interface (GUI version) and use it from help module.
  • adds: log:branches/help@19532:19574
  • Property svn:eol-style set to native
  • Property svn:keywords set to Author Date Id Revision
File size: 26.9 KB
Line 
1ARB change log
2
3Ticket references
4
5    Referenced ticket numbers are linked when you view this information
6    at http://help.arb-home.de/changes.html
7
8Major changes for next release:
9
10 - tweaked 'Helix settings' in EDIT4
11   - defaults changed for GG ('#'->'='), TT + UU ('+'->'#'), ambiguity codes (''->'%')
12   - added several predefined configs (traditional, two handling ambiguity codes)
13 - detect poorly aligned helical regions in editor (#854)
14 - include SINA (1.7.2 patched)
15   - interface auto-adapts to sina version (still compatible with 1.3; currently needs patched version for 1.7.2)
16   - added script arb_sina_install_from_fat_tarball.sh (allows to install sina from fat-tarballs provided via arb homepage)
17 - split alignments (#846)
18 - tweaked progress
19   - better estimation for NJ, ConsensusTree, matrix calculation + PVP
20   - support for longer periods; prefer overestimation
21   - log to console (estimates finish)
22 - FastTree
23   - added support for protein sequences.
24   - customizable from GUI (rate categories, NJ, bootstraps).
25   - upgraded to version 2.1.11
26   - arb now provides single+multi processor versions of FastTree
27 - NDS (Node display setup)
28   - specifying a zero WIDTH now means "unlimited" (backward compatible).
29   - avoid unwanted truncation (NDS-export, saved distance matrix).
30   - tree/export (using NDS)
31     - no longer truncates labels.
32     - group-labels are generated by NDS now.
33     - raise an error if non-ASCII characters are used in label (optionally).
34 - documentation (arb integrated help):
35   - length checked + corrected for preformatted text and titles
36   - minor layout changes
37   - link tickets and URLs (html)
38
39Fixes for arb-7.0.1 (31 Jan 2022):
40
41 - fix perl compatibility for macOS 12
42
43Major changes for arb-7.0 (1 Sep 2021):
44
45 - ARB PARSIMONY
46   * topology optimization
47     - now (by default) strictly restricted to marked/visible parts of the tree (#640)
48     - restriction now customizable (marked/all; visible/all)
49     - tree costs for protein-data were not independent from root-position (as expected by model; #633).
50       Caused infinite running optimization under some circumstances.
51     - optimize-modes now strictly restrict to clicked subtrees. single/repeated optimization possible.
52     - KL-optimizer
53       * static path reduction slightly changed meaning. changed default settings.
54       * removed randomness (was just covering some bugs)
55       * improved general optimization speed
56   * branchlength calculation
57     - "forgot" to recalculate lengths under some conditions. fixed.
58     - is now independent of tree-root position (#641)
59   * adding species
60     - 'add partial species' failed if two partial species had NO overlap (#609). fixed.
61     - in 'add species + NNI' local optimization quality depended on insert position. fixed.
62     - insertion of multiple species is now done independently (=unordered; #643)
63     - performance improved (esp. for many added species/big trees; #643)
64   * generally improved combine performance (using SSE)
65   * generally reduced the number of performed combines (skipping many useless)
66   * added function to randomize (parts of) the tree
67   * warns about insufficient sequence data (e.g. as result of too restrictive filtering; #631)
68   * fixed 'RESTORE' (crashed after deleting species from tree; #528)
69   * corrected handling of dots ('.') while combining ancestor sequences
70   * fixed a bunch of internal bugs (#620, #627, #645, ...)
71   * added species-info mode
72 - added missing translation tables (genetic codes 24-31)
73 - added amino acid code Xle(=J), which means Ile(=I) or Leu(=L)
74 - DNA realigner
75   * several unjustified failures will no longer happen (fixes #419 and most likely #145)
76     - correctly re-syncs after 'X' (if possible at all)
77     - no longer fails for 'B', 'J' and 'Z'
78     - accepts 3 or more consecutive IUPAC codes in DNA
79   * added option to cut-off DNA sequence (was done at end of sequence by old version. fixed)
80   * fixed several minor bugs (#563,..)
81 - ARB probeSpec: visualisation of probe set specificity (thanks to Paavo Jumppanen, CSIRO)
82 - species selections (editor configurations):
83   * visualisation of multiple selections in standard tree view (#658; example in database demo.arb)
84   * order can be changed; each configuration has a comment
85 - import/export (species,sequence):
86   * manage/edit/test import-/export-filter-definitions from inside ARB (#691)
87   * import can store configuration of imported species (#607)
88   * field transfer sets (#562) may be used to customize import/export behavior (also usable from arb merge-tool)
89   * corrected EMBL export filter (numbers at seq.data; #638)
90   * detected duplicates no longer abort complete import (#779)
91   * new CLI sequence exporter 'arb_export_seq_filtered' (#743)
92 - Tree shading (#443)
93   * according to values stored in database
94   * according to given topology (useful when comparing topologies)
95   * added customisable color ranges (#682)
96 - support for extra database compression (using gzip, bzip2, xz; #665); databases cannot be opened by versions before arb-7.0
97 - ARB_EDIT4:
98   * display selected database fields as flags (allowing to toggle their value; #261).
99     Example use: easily mark sequence as "curated" after manually checking its alignment.
100   * allow to load missing SAIs
101   * "view differences" to a reference sequence:
102      - customizable:
103        * char used for "equality" (i.e. what is displayed where a sequence is equal to selected sequence)
104        * case-sensitivity
105        * ignore different gap-types
106      - equal data also gets hidden in consensus
107      - refresh differences of all displayed sequences, when data of selected sequences changes
108      - change reference sequence using CTRL-R or automatically let it follow the cursor
109      - added hotkey to toggle mode: CTRL-D
110      - fixed minor bugs
111   * consensus calculation in ARB_EDIT4 and calculation of CONSENSUS SAI
112     - now both calculations are strictly consistent (#663):
113       * gaps are now ignored while deciding whether to simplify using IUPAC ambiguity codes
114       * IUPAC ambiguity codes encountered in sequence data are now counted proportionally (=> fewer 'N's occur in consensus)
115     - added sliders to consensus definition windows
116     - user defined consensus settings exchangable between both consensus setups
117     - fixed and updated documentation
118   * added species-info mode + database save (#52,#362)
119   * predefined SAI color translation for PVP
120 - changes to SAI generation
121   * MAX_FREQUENCY:
122     - considers IUPAC ambiguity codes proportionally
123     - amino acids: if MAX_FREQUENCY is below 10% SAI now shows '1' (prev. it did show '0', i.e. 100%)
124   * POS_VAR_BY_PARSIMONY (PVP):
125     - now (again) works with amino acid data (#782)
126     - added CLI tool 'arb_calc_pvp' (#701)
127   * implemented a SAI calculator (allows to modify or combine multiple SAIs)
128 - expand zombies in tree (unfold groups; #22)
129 - compare taxonomy (and mark differences; #651)
130 - search&query for taxonomic groups (#652)
131   - many search criteria (name, size, marked, nesting-level, ingroup-distance (#653), ...)
132   - search multiple trees, detect duplicate and missing groups
133   - operations on found groups (delete, rename, fold, mark)
134 - added concept of "inverse groups" (aka "keeled groups"; #735)
135 - group transfer between trees (#780):
136   - penalties can be customized in detail
137   - quality reports (to log and optionally to target name)
138 - synchronize positions of roots of multiple trees (#449)
139 - external (command line) aligners (#504):
140   * fixed incorrect handling of 'T' vs 'U': now all aligned sequences will contain the correct base depending on alignment type
141   * preserve gap-type ('-' vs '.') and upper-/lower-case of original alignment
142   * no longer ask what to do with aligned sequence, just overwrite it
143     - only warn about real sequence changes (so please do NOT ignore from now on!)
144 - config-managers:
145   * possibility to restore factory defaults
146   * added comment field for configurations
147   * added them throughout arb (#647)
148 - added slide controls throughout arb (#656)
149 - tree (display) options:
150   * fine grained scaling
151   * group display (shading, customizable counters (#118,#209), triangle clades, name display position)
152   * bootstrap values (filter by upper/lower limits, display position/styles, on/off toggle; #614)
153   * diagonal branch style (#578)
154   * parent branch position
155   * all options are now also supported by ARB_PARSIMONY
156   * improved auto-jump; now also works for groups
157   * added optional auto-unfolding (to selected group/species)
158   * select group on fold/unfold/create/move/..
159   * draw selected group in cursor-color (#709)
160   * added keys for tree-traversal (moving to selected species or group; #687)
161 - synchronized tree scrolling (#683)
162 - colorsets were invalidated by generating new IDs (#660). fixed.
163 - added alternate RAxML (DNA only; version 8.2.8)
164   - multicore support (automatically activates recommended number of threads)
165   - evaluation, optimization and extension of existing trees with RAxML (#681)
166 - fix performance of
167   * "format sequences" (broken in arb-6.0.x series; #702)
168   * nameserver for huge databases (#646)
169   * closing arb (if database uses fastload file; #649)
170 - ACI
171   - added boolean operators, numeric comparisons, floating point arithmetic and several other new commands
172   - allow access to other species via ID or accession number (findspec, ...)
173   - improved ACI debugging: more verbose tracing (console log accessible from inside ARB)
174 - NDS optionally uses only visible definitions
175 - Search&Query:
176   * sort results numerically (#203)
177   * recursive search through all fields (#773)
178 - Species information window: improved detachment, field selection (#695)
179 - improved macro compatibility:
180   * check compatibility with installed perl version during arb startup (#754)
181   * esp. tweaked compatibility of 'Search&Query' and 'Species information window'
182   * fixed a lot of internal names (missing or duplicated) which are used for macros (#429)
183 - improved OSX compatibility (thx to Jan Gerken)
184 - updated integrated documentation (#409)
185
186
187Fixes for arb-6.0.6 (22 Aug 2016):
188
189 - fixes for gcc 6.1.0
190 - tested gcc 4.9.4 + 5.4.0
191
192Fixes for arb-6.0.5 (4 May 2016):
193
194 - fixes for ubuntu 16.04 build
195
196Fixes for arb-6.0.4 (2 May 2016):
197
198 - fixes for OSX build (SIP, accepted compilers)
199
200Fixes for arb-6.0.3 (19 Nov 2015):
201
202 - fixes permission problems when multiple users share databases or ptservers (thx to Alan McCulloch)
203
204Fixes for arb-6.0.2 (8 Aug 2014):
205
206 - compile issues on Snow Leopard (OSX 10.6)
207 - merge Debian security fix for CVE-2008-5378
208 - small changes to build system for Debian
209 - add desktop integration files
210
211Fixes for arb-6.0.1 (22 Jul 2014):
212
213 - arb_parsimony
214   - skip unwanted automatic branchlength recalculations (e.g. by unfolding a group)
215   - corrected branchlength calculation for "Add marked partial species"
216   - dots were treated as gaps for protein sequences (now treated as 'X'; analog to DNA treating gaps as 'N'; #144). thx to Yan Shi for detecting that problem!
217 - print
218   - preview failed (showed empty postscript file)
219   - print to file now always saves in user home
220 - raxml (import tree with bootstrap values)
221
222Major changes for arb-6.0 (4 Jun 2014):
223
224 - merge databases allows to
225   - merge from an existing database into the database loaded in ARB_NT
226   - merge to existing databases from the database loaded in ARB_NT
227 - ARB can now
228   - be restarted with another database and
229   - a second instance of ARB can be opened
230 - ARB_DIST
231   - Detect clusters of species with similar sequences (OTUs)
232   - allow automatic recalculation of matrix and/or tree whenever some parameter or
233     data changes (only makes sense for smaller species sets)
234   - extract distance matrix from tree
235 - Rewrote chimera check. Allows filtering
236 - added RNACMA (computes clusters of correlated positions)
237 - PT-Server
238   - changed behavior
239     - no longer report less hits for a part of a probe than for the probe itself (occurred at 3'-end of alignment)
240     - reports previously missing hits in joined genes
241     - reports more hits at 3'-end of alignment (when using mismatches the PT-server now reports possible
242       matches that go beyond the end of the sequence)
243     - dots in the middle of the alignment act like the sequence ends there
244     - minimum probe length reduced to 2 (was 6)
245     - allow up to 50% of probe to mismatch
246   - performance
247     - optimized memory-estimation (will build in fewer passes)
248     - uses any number of passes (not only 1, 5, 25, ...)
249     - allows to define used memory by setting environment variable ARB_MEMORY
250     - reduced memory needed to build/run ptserver (approx. 50%)
251     - reduced size of indexfile (.pt) to ~50%
252     - fast startup of existing ptservers
253   - probe design
254     - faster in many cases
255     - allow to design probes of length 8 (previously 10)
256     - allow to design probes with different lengths (specifying min/max length)
257     - fixed number of outgroup hits reported when decreasing temperature
258       (now each outgroup member only occurs once)
259     - show possible reasons why no probes could be designed
260   - probe match (allow any number of mismatches)
261   - next relative search
262     - can be restricted to column ranges (needs a PT-Server calculated from aligned sequences)
263     - corrected and improved scaling of relative scores
264     - more accurate scores (due to fixes in PT-Server; see below)
265     - faster in many cases
266   - show errors from ptserver build in ARB
267 - fast-aligner
268   - searches next-relatives based on selected column-block
269   - align multiple column-blocks based on SAI
270 - Rewrote alignment adaption during merge
271 - Insert/delete columns using a SAI to define affected columns
272 - ARB_EDIT4
273   - improved support for using multiple edit-windows
274   - smoother refreshes
275   - tweaked ORF display
276 - tree importer/exporter
277   - ARBs extended newick format (with bootstrap values) handled more restrictive now
278   - fixed several bugs; improved errors/warnings
279 - consensus trees
280   - calculate from multiple existing trees (also allows to merge not completely overlapping trees)
281   - fixed NJ-bootstrapping (no longer drops species)
282 - tree display
283   - Show brackets on open groups (dendrogram tree only)
284   - rewrote IRS (folded) display
285   - fixed tree key-bindings (mark, fold, ...)
286   - improved several tree-commands (move, rotate, spread, length, width)
287 - added a branch analysis tool
288   - groups several functions previously available via menuitems (e.g. mark long branches, etc.)
289   - added leaf-distance analysis
290 - other tree functionality
291   - treelist sortable now
292   - new beautify-tree modes (radial tree / according to other tree)
293   - function to remove marked/zombies from ALL trees
294   - create multifurcations (by branchlength/bootstrap limit)
295   - toggle 100% bootstrap values
296 - tweaked printing (interface, overlapping)
297 - if YOU edit a helpfile it will be automatically packed into an archive ready to be sent to ARB developers
298 - probe design:
299   - added LOAD to result window
300 - automation
301   - macro recording works in ARB client applications (ARB_EDIT4, ARB_PARS, ARB_MERGE, ..)
302   - arb_ntree can execute macro from command line
303   - added "Never ask again" to modal question boxes (for better compatibility with macros)
304   - a macro can be called for all marked species (once for each)
305   - macros can be nested (i.e. can call other macros)
306 - support for user-specific customization:
307   - of GDE menus (in ~/.arb_prop/gde)
308   - of import/export filters (in ~/.arb_prop/filter)
309 - ACI (some new commands, bugfixes)
310 - updated/added external tools:
311   - added FastTree (version 2.1.7)
312   - added MAFFT (version 7.055)
313   - added MrBayes (version 3.2.1)
314   - added MUSCLE (version 3.8.31)
315   - added PHYML (2013/07/08; also kept old version 2.4.5)
316   - added PROBCONS (version 1.12)
317   - updated RAxML (version 7.7.2)
318 - load/save for window specific settings (e.g. allows to share parts of configuration with other users)
319 - Support for mouse-wheel
320 - many unlisted bugfixes
321 - many internal refactorings
322
323
324Fixes for arb_5.5 (15 Nov 2012):
325
326 * arb_5.4 was broken (several external tools missing)
327
328
329Fixes for arb_5.4 (14 Nov 2012):
330
331 * make it obvious when probe matches are truncated. Truncate all hits beyond 1 million (was 100000)
332 * fixed realigner (better interaction with fields 'transl_table' and 'codon_start'; improved error handling)
333 * fixed several compilation issues (OSX; recent distro releases)
334
335
336Fixes for arb_5.3 (10 Nov 2011):
337
338 - bugfixes
339   - fixed wrong absolute/ecoli position reported for some designed probes
340   - decompression error handling (pt-server build issues)
341   - fixed 'codon_start' generated with wrong type
342   - fixed a buffer overflow in ACI
343   - report failures to write to /tmp
344 - changes
345   - markSpecies.pl:
346     mark by accession number
347     partial/ambiguous matches
348 - internal fixes
349   - compilation fixes for OSX
350   - some patches for debian version (removed refs to xview, textedit, removed molphy(protml))
351   - removed obsolete dependency from libXp
352
353
354Fixes for arb_5.2 (5 Sep 2010):
355
356 - bugfixes
357   - quicksave did silently do nothing (especially not save anything) if an error occurred
358   - ARB_EDIT4: crashed when using config with MANY unknown species
359   - ARB_SECEDIT: crashed when trying to paint strand w/o any base
360   - ARB_NTREE/ARB_PARS: crashed when clicking on inner tree node w/o groupinfo
361 - changes
362   - ARB uses xdg-open to display web-pages
363 - internal fixes
364   - karmic koala (gcc 4.4.1)
365   - installation script
366   - arb build process uses xsltproc instead of sablotron
367
368
369Fixes for arb_5.1 (1 Oct 2009):
370
371 - fixed a bug in 'Create species from consensus' (created sequence was corrupted)
372 - fixed 2 bugs in optimize DB (alignment w/o data, missing transaction)
373 - updated installation instructions, fixed install script, added OSX instruction (thx to Matt Cottrell)
374 - fixed broken demo.arb
375
376
377Major changes for arb_5.00 (4 Sep 2009):
378
379 - ARB 64bit version
380 - new genome importer
381 - search for next relatives improved (normal search and fast-aligner)
382   - new parameters to precise search
383   - improved speed
384   - partial sequence reach normal scores
385 - search&query
386   - supports regular expressions and ACI
387   - track hit information
388   - result sorting
389 - Nameservers with add.field have to be started with default value
390   You need to correct parameter -f in lib/arb_tcp.dat (according to lib/arb_tcp_org.dat)
391 - multiple PT-servers may be used in parallel
392 - fixed multiprobe
393 - type-conversion for DB fields
394 - SILVA compatible import filters
395 - Newick tree export:
396   - optionally save in human-readable format (big)
397   - closer to newick standard format (quoting style, comment, special chars in data)
398 - Upgraded RAxML to 7.0.3 (many features now usable from ARB interface)
399 - Fixed sequence quality calculation
400 - Secondary structures for proteins (DSSP)
401 - Distance matrix (arb_dist): mark by distance to selected
402 - ARB core
403   - many bugfixes and improvements to reliability
404   - faster sorting (general speedup)
405   - improved sequence compression (avoid worse trees, better ratio)
406   - improved handling of temporary files (permission/removal)
407   - prints backtraces in userland
408   - regular expression are POSIX standard now
409 - macro record/playback
410   - fixed several bugs
411   - you need to re-record your old macros!
412 - GUI:
413   - disabled auto-focus, you need to click now
414   - auto-raise windows on access
415 - Minor things:
416   - Ubuntu: packet installation for ARB
417   - Fixed novice/expert mode
418   - Mark deep/degenerated branches
419   - Increased NDS entries
420 - up-to-date Mac port (thx to Matt Cottrell)
421
422Major changes in ARB 07.12.07org (7 Dec 2007):
423
424 - rewrote secondary structure editor
425 - Sequence quality check
426 - Nameserver may use one field additional to 'acc' (useful to keep multiple species with same acc)
427 - tweaked base frequency filter generation
428 - Normal export (not using readseq) improved:
429   - supports filters and gap removal
430   - optimized for big amount of data
431   - reworked export filters
432 - Display translation with different ORFs in EDIT4
433 - ARB exports in FIG 3.2 format (optionally in colors). Thanks to Elmar Pruesse.
434 - added PHYML 2.4.5 (thanks to Stephane Guidon for the permission to distribute that great tool)
435 - more compact display in EDIT4
436 - capable to use iso10646 fonts
437 - supports various gcc versions (2.95.3 - 4.1.1)
438 - fixed a bug in DB optimization (occurred when fields had bigger protection than current)
439 - Bootstrap circles may be displayed as ellipses; upper size limit configurable; uses
440   different color for size-limited circles; fixed xfig-export-bug
441 - Allows Branchlength <-> Bootstrap value transfer (lossy!)
442 - fixed several scaling bugs in "folded tree"-mode
443 - improved import-filter error-messages
444 - NDS-display of groups (e.g. in tree) is now handled by ACI-command 'taxonomy'. This gives
445   several new possibilities:
446   - export taxonomy via 'Export NDS list'
447   - display taxonomy in Editor etc.
448   - display of cascaded taxonomies
449   - display taxonomy of tree_1 in tree_2
450   - allows to write taxonomy into database field of species
451   - compare taxonomies of two trees
452   - ...
453 - ACI:
454   - many new ACI commands
455   - unified handling of binary ACI-operators
456   - tracing of ACI actions for debugging purpose
457 - ARB Neighbour joining:
458   - bootstrap limit configurable
459   - bugfix: when aborting bootstrap calculation, sometimes no tree was generated
460 - EDIT4:
461   - added unalign right (block-op)
462   - added 'Save loaded properties'
463 - GENE MAP:
464   - multiple views possible at the same time
465   - origin now at "12 o'clock"
466   - implemented 'jump to gene'
467 - tweaked file selection
468 - Enhanced Search Depth for Probe Match --> max 20 MM
469 - CLUSTALW:
470   - separated menus for fast and slow alignment
471   - most parameters accessible from inside ARB now
472 - upgraded to PHYLIP 3.6 (adds PROML)
473 - external programs may be called parallel (e.g. several treeing programs)
474 - fixed bugs in protml and integration of protml
475 - rewrote ASCII database import
476 - arb_repair for databases of any size (script for database repair)
477 - fixed bug in data compression
478 - increased internal cache size (alignments up to 400.000bp possible w/o performance collapse)
479 - ARBparsimony: increase hardcoded species limit (50.000 -> 250.000)
480 - GDE menus cleanup
481 - translation/re-alignment tweaked
482 - unalign right (EDIT4)
483 - visualization of SAIs in Probe Match Results
484 - changed formatting of probe match results; increase # of allowed matches to 100.000;
485   warn if results are truncated
486 - PT server for genes
487 - Probe design performance optimized
488 - fixed NEXUS export format
489 - exports group names into Newick format
490 - import XML tree files
491 - help for external tools now properly shown inside ARB
492
493Major changes in Beta 2003_08_22 (22 Aug 2003):
494
495 - automatic formatting of alignments
496 - SECEDIT may use EDIT4 colors
497 - fixed bootstrapping (DNAPARS, PROTPARS, PROTML(experimental!))
498 - updated clustalw to version 1.83
499 - Restore window sizes for ALL windows (too small sizes are ignored)
500 - new algorithm to add partial sequences to an existing tree
501 - PROT-parsimony was completely redesigned and works now most similar to DNA/RNA-parsimony
502 - Top area of ARB_NTREE may be reduced to maximize display area
503 - All arb menus may be detached (click dashed line at top of menu)
504 - visualization of SAIs (as background color behind Sequences)
505 - ARB_EDIT4 may save/use alignment-specific and alignment-type-specific properties
506 - PT-server occupies more memory => does less passes; more diagnostic output
507 - small changes to status window (unhide behavior/time estimation)
508 - menus and menu-hotkeys reorganized
509 - colored buttons in color config windows
510 - alignment concatenation (e.g. several different genes)
511 - merging data of similar species (according selected database field)
512 - keyboard commands for ARB_NTREE (mark/unmark/invert, collapse/expand)
513 - expanded sellists
514 - save/load fixed for multi probes
515 - Binary SAIs are editable in ARB_EDIT4
516 - Information windows are detachable (allows to have multiple windows showing different items)
517 - Scanning for hidden/unknown database fields improved and separated;
518   possibility to remove unused fields.
519 - new tabbed format in 'Export NDS' and 'Export matrix' (useful for star-calc/excel/etc.)
520 - updated fastDNAml to 1.2.2
521 - added AxML (accelerated fastDNAml 1.2.2)
522 - Field transfer definitions for exporting gene-species
523 - File Selection: - recursive search available
524 - The ARB_NTREE macro recording/execution has been fixed
525 - Colorize species (see demo.arb)
526 - Fixed missing-character-bug in Xfig, Print and Edit4-Info-Display
527 - 'IslandHopper' -- a new integrated aligner (beta)
528 - Many improvements and bugfixes to secondary structure editor:
529   - highlighting of search (i.e for probes) like in EDIT4
530   - interactive constraint editing (stretch/compress)
531   - probe info
532   - editing secondary structure in XFIG now possible
533   - visualization of SAIs
534 - import reads Unix, DOS, and MAC linefeeds
535 - NTREE/SAI/Etc/GnuPlot: calls gnuplot directly; more plotting features; basic help
536 - tree and sequence export to XML ( DTDs are provided in ./lib/dtd )
537   (reloading of these XML files is planned for the future)
538 - fixed problems with phylip-tree import/export (bootstrap values,comments,...)
539 - search in all database fields possible ('[all fields]')
540 - up to 10 quicksaves are kept
541 - new ACI functions: upper, lower, caps, eval
542 - variables for import filter programming
543 - extract gene-species: creates acc; extraction to existing alignments
544 - sequence of selected gene is mirrored in ARB_EDIT4/local_signature
545   (=> selected gene can be highlighted in primary editor)
546 - PCR primer-design for single genes
547 - when selecting a gene, the corresponding gene-species is selected (if found)
548 - save configuration for several windows (e.g. Search&Query, WWW, NDS, ...)
549 - file selection box in import window
550 - mark item with double click works in all search&query windows
551 - User masks: create new; 'edit enable' and 'marked' toggles (like in info window)
552 - Fixed command line help for all Arb-modules
553 - Fixed problem parsing fonts (should fix display problems with default fonts)
554 - Mark mode now works in list-view as well (ARB_NTREE)
555 - Fixed appearance of 'tiny little boxes' (everywhere)
556 - Redesign of ARB help:
557     - a HTML version is in $ARBHOME/lib/help_html
558     - a text version is in $ARBHOME/lib/help (like before, but now generated)
559
560Major changes in Beta 2001_11_07 (7 Nov 2001):
561
562 - design probes to maximum length of 60 nucleotides
563 - fastAligner1.03 bug fixed (chooses best match now in 'auto search' mode)
564 - import default changed to foreign data format, ali name '16s'
565 - printing of multi-page-trees works again
566 - implemented user defineable masks to access database fields
567 - fixed bugs in pt-server (lockup, unknown species just after building pt-server)
568 - improved performance during pt-server-build
569 - several programs coming along with ARB where updated (PHYLIP,...)
570 - reads EMBL genom files
571 - support for experiments (genom databases only)
572
573Major changes in Beta 2001_07_24 (24 Jul 2001):
574
575 - basic support for genoms (Gene Map, reads Genebank files)
576 - ported to libc6
577
578Changes in ancient versions (last century):
579
580 - see http://help.arb-home.de/version.html
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