Opened 11 years ago

Last modified 9 years ago

#421 new enhancement

Chimera check shall optionally annotate possible sources

Reported by: westram Owned by: westram
Priority: normal Milestone:
Component: no idea Version: SVN
Keywords: Cc:

Description (last modified by westram)

  • allow to specify "column-clusters" defined by quality-output of existing chimera check
    • e.g. specifying sth like "123,789" defines 3 column-types:
      • all columns with quality 1, 2 or 3
      • same for 7,8 and 9
      • rest (will be considered irrelevant)
    • for each column-type find column-clusters, specified by
      • max. percentage of "other qualities" inside the cluster and
      • min. length of cluster
  • perform relative-search for each column-cluster (do position-specific search, maybe also global search if none found)
  • for any found relative. calculate
    • mean degree of relatedness for each cluster type
    • mean sequence offset (only applies if global search is performed)
  • sort found relatives "according to their probability to be a source of the suspected chimera"
    • annotate into a database field of the chimera

Change History (2)

comment:1 Changed 11 years ago by westram

  • Description modified (diff)

comment:2 Changed 9 years ago by westram

  • Milestone work2013 deleted
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